Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system

European Journal of Neuroscience

Volumn 17, Issue 2, 2003, Pages 260-270

  Rosenblad, Carl ^a   Georgievska, Biljana ^b   Kirik, Deniz ^b  

^a NsGene AS   (Denmark)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Autoradiography; Lentivirus; Rat; Striatum; Substantia nigra

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BRAIN MONOAMINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GREEN FLUORESCENT PROTEIN; MAZINDOL; MESSENGER RNA; RECOMBINANT PROTEIN; SPIPERONE DERIVATIVE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BRAIN NERVE CELL; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE UPTAKE; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; DOWN REGULATION; DRUG BINDING; DRUG BRAIN LEVEL; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOREACTIVITY; MOLECULAR BIOLOGY; NERVE ENDING; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SUBSTANTIA NIGRA; SYNAPSE; TISSUE DISTRIBUTION; VENTRAL TEGMENTUM;

ANIMALS; CORPUS STRIATUM; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC VECTORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LENTIVIRUS; LUMINESCENT PROTEINS; NERVE GROWTH FACTORS; NEURONS; PLASMIDS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUBSTANTIA NIGRA; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 0037267170     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02456.x     Document Type: Article

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