-
1
-
-
19144369706
-
Gene therapy for amyotrophic lateral sclerosis (ALS) using a polymer encapsulated xenogenic cell line engineered to secrete hCNTF
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 851-860
-
-
Aebischer, P.1
Pochon, N.A.2
Heyd, B.3
Deglon, N.4
Joseph, J.M.5
Zurn, A.D.6
Baetge, E.E.7
Hammang, J.P.8
Goddard, M.9
Lysaght, M.10
Kaplan, F.11
Kato, A.C.12
Schluep, M.13
Hirt, L.14
Regli, F.15
Porchet, F.16
De Tribolet, N.17
-
2
-
-
15844381714
-
Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients
-
(1996)
Nat. Med.
, vol.2
, pp. 696-699
-
-
Aebischer, P.1
Schluep, M.2
Deglon, N.3
Joseph, J.M.4
Hirt, L.5
Heyd, B.6
Goddard, M.7
Hammang, J.P.8
Zurn, A.D.9
Kato, A.C.10
Regli, F.11
Baetge, E.E.12
-
8
-
-
0033135782
-
Adenovirus-mediated transgene expression in nonhuman primate brain
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1175-1184
-
-
Bohn, M.C.1
Choi-Lundberg, D.L.2
Davidson, B.L.3
Leranth, C.4
Kozlowski, D.A.5
Smith, J.C.6
O'Banion, M.K.7
Redmond D.E., Jr.8
-
12
-
-
0031019795
-
Dopaminergic neurons protected from degeneration by GDNF gene therapy
-
(1997)
Science
, vol.275
, pp. 838-841
-
-
Choi-Lundberg, D.L.1
Lin, Q.2
Chang, Y.N.3
Chiang, Y.L.4
Hay, C.M.5
Mohajeri, H.6
Davidson, B.L.7
Bohn, M.C.8
-
13
-
-
0032423612
-
Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor
-
(1998)
Exp. Neurol.
, vol.154
, pp. 261-275
-
-
Choi-Lundberg, D.L.1
Lin, Q.2
Schallert, T.3
Crippens, D.4
Davidson, B.L.5
Chang, Y.N.6
Chiang, Y.L.7
Qian, J.8
Bardwaj, L.9
Bohn, M.C.10
-
16
-
-
0032893035
-
A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 349-354
-
-
Corti, O.1
Sabate, O.2
Horellou, P.3
Colin, P.4
Dumas, S.5
Buchet, D.6
Buc-Caron, M.H.7
Mallet, J.8
-
19
-
-
0033977265
-
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 179-190
-
-
Deglon, N.1
Tseng, J.L.2
Bensadoun, J.C.3
Zurn, A.D.4
Arsenijevic, Y.5
Pereira de Almeida, L.6
Zufferey, R.7
Trono, D.8
Aebischer, P.9
-
23
-
-
0032538911
-
Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys
-
(1998)
J. Comp. Neurol.
, vol.401
, pp. 253-265
-
-
Emborg, M.E.1
Ma, S.Y.2
Mufson, E.J.3
Levey, A.I.4
Taylor, M.D.5
Brown, W.D.6
Holden, J.E.7
Kordower, J.H.8
-
28
-
-
0033029635
-
Minimum requirements for efficient transduction of dividing and nondividing cells by feline immunodeficiency virus vectors
-
(1999)
J. Virol.
, vol.73
, pp. 4991-5000
-
-
Johnston, J.C.1
Gasmi, M.2
Lim, L.E.3
Elder, J.H.4
Yee, J.K.5
Jolly, D.J.6
Campbell, K.P.7
Davidson, B.L.8
Sauter, S.L.9
-
32
-
-
0032143368
-
Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
-
(1998)
Exp. Neurol.
, vol.152
, pp. 259-277
-
-
Kirik, D.1
Rosenblad, C.2
Bjorklund, A.3
-
33
-
-
0006825141
-
-
D. Kirik, C. Rosenblad, A. Bjorklund, Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on site of administration of the trophic factor, Eur. J. Neurosci. (in press).
-
-
-
-
36
-
-
0032752994
-
Lentiviral gene transfer to the nonhuman primate brain
-
(1999)
Exp. Neurol.
, vol.160
, pp. 1-16
-
-
Kordower, J.H.1
Bloch, J.2
Ma, S.Y.3
Chu, Y.4
Palfi, S.5
Roitberg, B.Z.6
Emborg, M.7
Hantraye, P.8
Deglon, N.9
Aebischer, P.10
-
37
-
-
0006827561
-
-
J.H. Kordower, M. Emborg, J. Bloch, S.Y. Ma, Y. Chu, L. Leventhal, J. McBride, E.-Y. Chen, S. Palfi, B.Z. Roitberg, W.D. Brown, J.E. Holden, R. Pyzalski, M.D. Taylor, P. Carvey, Z. Ling, D. Trono, P. Hantraye, N. Deglon, P. Aebischer, Lentiviral vector-mediated expression of GDNF prevents motor deficits and nigrostriatal degeneration in nonhuman primate models of Parkinson's disease, Science (in press).
-
-
-
-
39
-
-
0031550611
-
Glial cell line-derived neurotrophic factor induces the dopaminergic and cholinergic phenotype and increases locomotor activity in aged Fischer 344 rats
-
(1997)
Neuroscience
, vol.77
, pp. 745-752
-
-
Lapchak, P.A.1
Miller, P.J.2
Jiao, S.3
-
40
-
-
0032819559
-
Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus [see comments]
-
(1999)
Gene Ther.
, vol.6
, pp. 1368-1379
-
-
Lawrence, M.S.1
Foellmer, H.G.2
Elsworth, J.D.3
Kim, J.H.4
Leranth, C.5
Kozlowski, D.A.6
Bothwell, A.L.7
Davidson, B.L.8
Bohn, M.C.9
Redmond D.E., Jr.10
-
44
-
-
0032708890
-
Recombinant adeno-associated viral vector-mediated glial cell line-derived neurotrophic factor gene transfer protects nigral dopamine neurons after onset of progressive degeneration in a rat model of Parkinson's disease
-
(1999)
Exp. Neurol.
, vol.160
, pp. 205-214
-
-
Mandel, R.J.1
Snyder, R.O.2
Leff, S.E.3
-
46
-
-
0032757387
-
Stable gene transfer to the nervous system using a non-primate lentiviral vector
-
(1999)
Gene Ther.
, vol.6
, pp. 1808-1818
-
-
Mitrophanous, K.1
Yoon, S.2
Rohll, J.3
Patil, D.4
Wilkes, F.5
Kim, V.6
Kingsman, S.7
Kingsman, A.8
Mazarakis, N.9
-
49
-
-
13044304200
-
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12816-12821
-
-
Morral, N.1
O'Neal, W.2
Rice, K.3
Leland, M.4
Kaplan, J.5
Piedra, P.A.6
Zhou, H.7
Parks, R.J.8
Velji, R.9
Aguilar-Cordova, E.10
Wadsworth, S.11
Graham, F.L.12
Kochanek, S.13
Carey, K.D.14
Beaudet, A.L.15
-
52
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
57
-
-
0031879481
-
Regulation of gene expression in vivo following transduction by two separate rAAV vectors
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 757-761
-
-
Rendahl, K.G.1
Leff, S.E.2
Otten, G.R.3
Spratt, S.K.4
Bohl, D.5
Van Roey, M.6
Donahue, B.A.7
Cohen, L.K.8
Mandel, R.J.9
Danos, O.10
Snyder, R.O.11
-
58
-
-
0033978389
-
In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member Neublastin/Artemin
-
(2000)
Mol. Cell. Neurosci.
, vol.15
, pp. 199-214
-
-
Rosenblad, C.1
Gronborg, M.2
Hansen, C.3
Blom, N.4
Meyer, M.5
Johansen, J.6
Dago, L.7
Kirik, D.8
Patel, U.A.9
Lundberg, C.10
Trono, D.11
Bjorklund, A.12
Johansen, T.E.13
-
59
-
-
0034097605
-
Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model
-
(2000)
Exp. Neurol.
, vol.161
, pp. 503-516
-
-
Rosenblad, C.1
Kirik, D.2
Bjorklund, A.3
-
61
-
-
0000609138
-
Adeno-associated viral vectors
-
Friedmann T. (Ed.), The Development of Human Gene Therapy, New York: Cold Spring Harbor
-
(1999)
, pp. 131-172
-
-
Samulski, R.J.1
Sally, M.2
Muzyczka, N.3
-
62
-
-
12944315064
-
Optimization of the helper-dependent adenovirus system for production and potency in vivo
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1002-1007
-
-
Sandig, V.1
Youil, R.2
Bett, A.J.3
Franlin, L.L.4
Oshima, M.5
Maione, D.6
Wang, F.7
Metzker, M.L.8
Savino, R.9
Caskey, C.T.10
-
63
-
-
0028220834
-
Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde and immunocytochemical study in the rat
-
(1994)
Neuroscience
, vol.59
, pp. 401-415
-
-
Sauer, H.1
Oertel, W.H.2
-
64
-
-
0033972740
-
Lentiviral vectors: turning a deadly foe into a therapeutic agent
-
(2000)
Gene Ther.
, vol.7
, pp. 20-23
-
-
Trono, D.1
-
68
-
-
0033022953
-
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
-
(1999)
Gene Ther.
, vol.6
, pp. 973-985
-
-
Zolotukhin, S.1
Byrne, B.J.2
Mason, E.3
Zolotukhin, I.4
Potter, M.5
Chesnut, K.6
Summerford, C.7
Samulski, R.J.8
Muzyczka, N.9
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