메뉴 건너뛰기




Volumn 14, Issue 1, 2003, Pages 156-172

A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN B; FUNGAL ENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MIXED LINEAGE KINASE 3; PHOSPHATASE; PLASMID DNA; PROTEIN KINASE NIMA; PROTEIN SERINE THREONINE KINASE; RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 0037238388     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-02-0115     Document Type: Article
Times cited : (43)

References (93)
  • 1
    • 0034237676 scopus 로고    scopus 로고
    • Spindle assembly and the art of regulating microtubule dynamics by MAPs and Stathmin/Op18
    • Andersen, S.S. (2000). Spindle assembly and the art of regulating microtubule dynamics by MAPs and Stathmin/Op18. Trends Cell Biol. 10, 261-267.
    • (2000) Trends Cell Biol. , vol.10 , pp. 261-267
    • Andersen, S.S.1
  • 2
    • 0032499243 scopus 로고    scopus 로고
    • Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system
    • Arama, E., Yanai, A., Kilfin, G., Bernstein, A., and Motro, B. (1998). Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system. Oncogene 16, 1813-1823.
    • (1998) Oncogene , vol.16 , pp. 1813-1823
    • Arama, E.1    Yanai, A.2    Kilfin, G.3    Bernstein, A.4    Motro, B.5
  • 3
    • 0028353367 scopus 로고
    • PCM-1, a 228-kD centrosome autoantigen with a distinct cell cycle distribution
    • Balczon, R., Bao, L., and Zimmer, W.E. (1994). PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution. J. Cell Biol. 124, 783-793.
    • (1994) J. Cell Biol. , vol.124 , pp. 783-793
    • Balczon, R.1    Bao, L.2    Zimmer, W.E.3
  • 4
    • 0026686259 scopus 로고
    • Cloning of chromosome I DNA from Saccharomyces cerevisiae: Analysis of the FUN52 gene, whose product has homology to protein kinases
    • Barton, A.B., Davies, C.J., Hutchison, C.A., and Kaback, D.B. (1992). Cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the FUN52 gene, whose product has homology to protein kinases. Gene 117, 137-140.
    • (1992) Gene , vol.117 , pp. 137-140
    • Barton, A.B.1    Davies, C.J.2    Hutchison, C.A.3    Kaback, D.B.4
  • 5
    • 0025109181 scopus 로고
    • Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts
    • Belmont, L.D., Hyman, A.A., Sawin, K.E., and Mitchison, T.J. (1990). Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts. Cell 62, 579-589.
    • (1990) Cell , vol.62 , pp. 579-589
    • Belmont, L.D.1    Hyman, A.A.2    Sawin, K.E.3    Mitchison, T.J.4
  • 6
    • 0035923665 scopus 로고    scopus 로고
    • SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
    • Bennett, B.L. et al. (2001). SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. USA 98, 13681-13686.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 13681-13686
    • Bennett, B.L.1
  • 7
    • 0021278818 scopus 로고
    • S-phase, G2, and nuclear division mutants of Aspergillus nidulans
    • Bergen, L.G., Upshall, A., and Morris, N.R. (1984). S-phase, G2, and nuclear division mutants of Aspergillus nidulans. J. Bacteriol. 159, 114-119.
    • (1984) J. Bacteriol. , vol.159 , pp. 114-119
    • Bergen, L.G.1    Upshall, A.2    Morris, N.R.3
  • 8
    • 0040211565 scopus 로고    scopus 로고
    • Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation
    • Bock, B.C., Vacratsis, P.O., Qamirani, E., and Gallo, K.A. (2000). Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation. J. Biol. Chem, 275, 14231-14241.
    • (2000) J. Biol. Chem. , vol.275 , pp. 14231-14241
    • Bock, B.C.1    Vacratsis, P.O.2    Qamirani, E.3    Gallo, K.A.4
  • 10
    • 0028786020 scopus 로고
    • A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
    • Burbelo, P.D., Drechsel, D., and Hall, A. (1995). A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases. J. Biol. Chem. 270, 29071-29074.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29071-29074
    • Burbelo, P.D.1    Drechsel, D.2    Hall, A.3
  • 11
    • 0027215350 scopus 로고
    • Novel protein kinases expressed in human breast cancer
    • Cance, W,G., Craven, R.J., Weiner, T,M., and Liu, E.T. (1993). Novel protein kinases expressed in human breast cancer. Int. J. Cancer 54, 571-577.
    • (1993) Int. J. Cancer , vol.54 , pp. 571-577
    • Cance, W.G.1    Craven, R.J.2    Weiner, T.M.3    Liu, E.T.4
  • 12
    • 0033005733 scopus 로고    scopus 로고
    • Accessory protein regulation of microtubule dynamics throughout the cell cycle
    • Cassimeris, L. (1999). Accessory protein regulation of microtubule dynamics throughout the cell cycle. Curr. Opin. Cell Biol. 11, 134-141.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 134-141
    • Cassimeris, L.1
  • 13
    • 0033046083 scopus 로고    scopus 로고
    • NIMA-related kinases: Isolation and characterization of murine nek3 and nek4 cDNAs, and chromosomal localization of nek1, nek2 and nek3
    • Chen, A., Yanai, A., Arama, E., Kilfin, G., and Motro, B. (1999). NIMA-related kinases: isolation and characterization of murine nek3 and nek4 cDNAs, and chromosomal localization of nek1, nek2 and nek3. Gene 234, 127-137.
    • (1999) Gene , vol.234 , pp. 127-137
    • Chen, A.1    Yanai, A.2    Arama, E.3    Kilfin, G.4    Motro, B.5
  • 14
    • 0023392945 scopus 로고
    • High-efficiency transformation of mammalian cells by plasmid DNA
    • Chen, C., and Okayama, H. (1987). High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2745-2752
    • Chen, C.1    Okayama, H.2
  • 15
    • 0032503045 scopus 로고    scopus 로고
    • The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinases (SAPKs/JNKs)
    • Clerk, A., and Sugden, P.H. (1998). The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinases (SAPKs/JNKs). FEBS Lett. 426, 93-96.
    • (1998) FEBS Lett. , vol.426 , pp. 93-96
    • Clerk, A.1    Sugden, P.H.2
  • 16
    • 0032473350 scopus 로고    scopus 로고
    • The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1
    • Crenshaw, D.G., Yang, J., Means, A.R., and Kornbluth, S. (1998). The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1. EMBO J. 17, 1315-1327.
    • (1998) EMBO J. , vol.17 , pp. 1315-1327
    • Crenshaw, D.G.1    Yang, J.2    Means, A.R.3    Kornbluth, S.4
  • 17
    • 0345363151 scopus 로고    scopus 로고
    • Mini spindles: A gene encoding a conserved microtubule-associated protein required for the integrity of the mitotic spindle in Drosophila
    • Cullen, C.F., Deak, P., Glover, D.M., and Ohkura, H. (1999). mini spindles: a gene encoding a conserved microtubule-associated protein required for the integrity of the mitotic spindle in Drosophila. J. Cell Biol. 146, 1005-1018.
    • (1999) J. Cell Biol. , vol.146 , pp. 1005-1018
    • Cullen, C.F.1    Deak, P.2    Glover, D.M.3    Ohkura, H.4
  • 18
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis, R.J. (2000). Signal transduction by the JNK group of MAP kinases. Cell 103, 239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 19
    • 0034604329 scopus 로고    scopus 로고
    • Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans
    • De Souza, C.P., Osmani, A.H., Wu, L.P., Spotts, J.L., and Osmani, S.A. (2000). Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans. Cell 102, 293-302.
    • (2000) Cell , vol.102 , pp. 293-302
    • De Souza, C.P.1    Osmani, A.H.2    Wu, L.P.3    Spotts, J.L.4    Osmani, S.A.5
  • 20
    • 0022560286 scopus 로고
    • Microtubule dynamics during the cell cycle: The effects of taxol and nocodazole on the microtubule system of PtK2 cells at different stages of the mitotic cycle
    • DeBrabander, M., Geuens, G., Nuydens, R., Willebrords, R., Aerts, F., DeMey, J., and McIntosh, J.R. (1986). Microtubule dynamics during the cell cycle: the effects of taxol and nocodazole on the microtubule system of PtK2 cells at different stages of the mitotic cycle. Int. Rev. Cytol. 101, 215-275.
    • (1986) Int. Rev. Cytol. , vol.101 , pp. 215-275
    • DeBrabander, M.1    Geuens, G.2    Nuydens, R.3    Willebrords, R.4    Aerts, F.5    DeMey, J.6    McIntosh, J.R.7
  • 21
    • 0025949412 scopus 로고
    • Nuclear targeting sequences - A consensus?
    • Dingwall, C., and Laskey, R.A. (1991). Nuclear targeting sequences - a consensus? Trends Biochem. Sci. 16, 478-481.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 478-481
    • Dingwall, C.1    Laskey, R.A.2
  • 22
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S.M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 23
    • 0028140164 scopus 로고
    • PTK1, a novel protein kinase required for proliferation of human melanocytes
    • Ezoe, K., Lee, S.T., Strunk, K.M., and Spritz, R.A. (1994). PTK1, a novel protein kinase required for proliferation of human melanocytes. Oncogene 9, 935-938.
    • (1994) Oncogene , vol.9 , pp. 935-938
    • Ezoe, K.1    Lee, S.T.2    Strunk, K.M.3    Spritz, R.A.4
  • 24
    • 0032518798 scopus 로고    scopus 로고
    • A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
    • Fry, A.M., Meraldi, P., and Nigg, E.A. (1998). A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. EMBO J. 17, 470-481.
    • (1998) EMBO J. , vol.17 , pp. 470-481
    • Fry, A.M.1    Meraldi, P.2    Nigg, E.A.3
  • 25
    • 0027276149 scopus 로고
    • A Trypanosoma brucei gene family encoding protein kinases with catalytic domains structurally related to Nek1 and NIMA
    • Gale, M., Jr., and Parsons, M. (1993). A Trypanosoma brucei gene family encoding protein kinases with catalytic domains structurally related to Nek1 and NIMA. Mol. Biochem. Parasitol. 59, 111-121.
    • (1993) Mol. Biochem. Parasitol. , vol.59 , pp. 111-121
    • Gale M., Jr.1    Parsons, M.2
  • 26
    • 0028340349 scopus 로고
    • Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity
    • Gallo, K.A., Mark, M.R., Scadden, D.T., Wang, Z., Gu, Q., and Godowski, P.J. (1994). Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity. J. Biol. Chem. 269, 15092-15100.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15092-15100
    • Gallo, K.A.1    Mark, M.R.2    Scadden, D.T.3    Wang, Z.4    Gu, Q.5    Godowski, P.J.6
  • 27
    • 0034687657 scopus 로고    scopus 로고
    • The TACC domain identifies a family of centrosomal proteins that can interact with microtubules
    • Gergely, F., Karlsson, C., Still, I., Cowell, J., Kilmartin, J., and Raff, J.W. (2000). The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. Proc. Natl. Acad. Sci. USA 97, 14352-14357.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14352-14357
    • Gergely, F.1    Karlsson, C.2    Still, I.3    Cowell, J.4    Kilmartin, J.5    Raff, J.W.6
  • 28
    • 0037017398 scopus 로고    scopus 로고
    • Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
    • Giet, R., McLean, D., Descamps, S., Lee, M.J., Raff, J.W., Prigent, C., and Glover, D.M. (2002). Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J. Cell Biol. 156, 437-451.
    • (2002) J. Cell Biol. , vol.156 , pp. 437-451
    • Giet, R.1    McLean, D.2    Descamps, S.3    Lee, M.J.4    Raff, J.W.5    Prigent, C.6    Glover, D.M.7
  • 29
    • 0033135621 scopus 로고    scopus 로고
    • The JNK/SAPK activator mixed lineage kinase 3 (MLK3) transforms NIH 3T3 cells in a MEK-dependent fashion
    • Hartkamp, J., Troppmair, J., and Rapp, U.R. (1999). The JNK/SAPK activator mixed lineage kinase 3 (MLK3) transforms NIH 3T3 cells in a MEK-dependent fashion. Cancer Res. 59, 2195-2202.
    • (1999) Cancer Res. , vol.59 , pp. 2195-2202
    • Hartkamp, J.1    Troppmair, J.2    Rapp, U.R.3
  • 31
    • 0037013225 scopus 로고    scopus 로고
    • Purification, cloning, and characterization of Nek8, a novel NIMA- related kinase, and its candidate substrate Bicd2
    • Holland, P.M., Milne, A., Garka, K., Johnson, R.S., Willis, C., Sims, J.E., Rauch, C.T., Bird, T.A., and Virca, G.D. (2002). Purification, cloning, and characterization of Nek8, a novel NIMA- related kinase, and its candidate substrate Bicd2. J. Biol. Chem. 277, 16229-16240.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16229-16240
    • Holland, P.M.1    Milne, A.2    Garka, K.3    Johnson, R.S.4    Willis, C.5    Sims, J.E.6    Rauch, C.T.7    Bird, T.A.8    Virca, G.D.9
  • 32
    • 23444453486 scopus 로고
    • MLK-3: Identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain
    • Ing, Y.L., Leung, I.W., Heng, H.H., Tsui, L.C., and Lassam, N.J. (1994). MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain. Oncogene 9, 1745-1750.
    • (1994) Oncogene , vol.9 , pp. 1745-1750
    • Ing, Y.L.1    Leung, I.W.2    Heng, H.H.3    Tsui, L.C.4    Lassam, N.J.5
  • 33
    • 0028060578 scopus 로고
    • Cell cycle arrest by Colcemid differs in human normal and tumor cells
    • Jha, M.N., Bamburg, J.R., and Bedford, J.S. (1994). Cell cycle arrest by Colcemid differs in human normal and tumor cells. Cancer Res. 54, 5011-5015.
    • (1994) Cancer Res. , vol.54 , pp. 5011-5015
    • Jha, M.N.1    Bamburg, J.R.2    Bedford, J.S.3
  • 34
    • 0025369518 scopus 로고
    • Isolation of a novel protein kinase-encoding gene from yeast by oligodeoxyribonucleotide probing
    • Jones, D.G., and Rosamond, J. (1990). Isolation of a novel protein kinase-encoding gene from yeast by oligodeoxyribonucleotide probing. Gene 90, 87-92.
    • (1990) Gene , vol.90 , pp. 87-92
    • Jones, D.G.1    Rosamond, J.2
  • 35
    • 0034283237 scopus 로고    scopus 로고
    • Isolation and characterization of two evolutionarily conserved murine kinases (Nek6 and nek7) related to the fungal mitotic regulator, NIMA
    • Kandli, M., Feige, E., Chen, A., Kilfin, G., and Motro, B. (2000). Isolation and characterization of two evolutionarily conserved murine kinases (Nek6 and nek7) related to the fungal mitotic regulator, NIMA. Genomics 68, 187-196.
    • (2000) Genomics , vol.68 , pp. 187-196
    • Kandli, M.1    Feige, E.2    Chen, A.3    Kilfin, G.4    Motro, B.5
  • 36
    • 0033971177 scopus 로고    scopus 로고
    • Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3
    • Kelkar, N., Gupta, S., Dickens, M., and Davis, R.J. (2000). Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. Mol. Cell. Biol. 20, 1030-1043.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1030-1043
    • Kelkar, N.1    Gupta, S.2    Dickens, M.3    Davis, R.J.4
  • 37
    • 0033538844 scopus 로고    scopus 로고
    • The sudden recruitment of gamma-tubulin to the centrosome at the onset of mitosis and its dynamic exchange throughout the cell cycle, do not require microtubules
    • Khodjakov, A., and Rieder, C.L. (1999). The sudden recruitment of gamma-tubulin to the centrosome at the onset of mitosis and its dynamic exchange throughout the cell cycle, do not require microtubules. J. Cell Biol. 146, 585-596.
    • (1999) J. Cell Biol. , vol.146 , pp. 585-596
    • Khodjakov, A.1    Rieder, C.L.2
  • 40
    • 0037007211 scopus 로고    scopus 로고
    • The fission yeast NIMA kinase Fin1p is required for spindle function and nuclear envelope integrity
    • Krien, M.J., West, R.R., John, U.P., Koniaras, K., McIntosh, J.R., and O'Connell, M.J. (2002). The fission yeast NIMA kinase Fin1p is required for spindle function and nuclear envelope integrity. EMBO J. 21, 1713-1722.
    • (2002) EMBO J. , vol.21 , pp. 1713-1722
    • Krien, M.J.1    West, R.R.2    John, U.P.3    Koniaras, K.4    McIntosh, J.R.5    O'Connell, M.J.6
  • 41
    • 0033615982 scopus 로고    scopus 로고
    • Centriolar satellites: Molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis
    • Kubo, A., Sasaki, H., Yuba-Kubo, A., Tsukita, S., and Shiina, N. (1999). Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis. J. Cell Biol. 147, 969-980.
    • (1999) J. Cell Biol. , vol.147 , pp. 969-980
    • Kubo, A.1    Sasaki, H.2    Yuba-Kubo, A.3    Tsukita, S.4    Shiina, N.5
  • 42
    • 0037085301 scopus 로고    scopus 로고
    • Role of MLK3-mediated Activation of p70 S6 Kinase in Rac1 Transformation
    • Lambert, J.M., Karnoub, A.E., Graves, L.M., Campbell, S.L., and Der, C.J. (2002). Role of MLK3-mediated Activation of p70 S6 Kinase in Rac1 Transformation. J. Biol. Chem. 277, 4770-7.
    • (2002) J. Biol. Chem. , vol.277 , pp. 4770-4777
    • Lambert, J.M.1    Karnoub, A.E.2    Graves, L.M.3    Campbell, S.L.4    Der, C.J.5
  • 43
    • 0026671553 scopus 로고
    • A mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells
    • Letwin, K., Mizzen, L., Motro, B., Ben-David, Y., Bernstein, A., and Pawson, T. (1992). A mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells. EMBO J. 11, 3521-3531.
    • (1992) EMBO J. , vol.11 , pp. 3521-3531
    • Letwin, K.1    Mizzen, L.2    Motro, B.3    Ben-David, Y.4    Bernstein, A.5    Pawson, T.6
  • 44
    • 0032484215 scopus 로고    scopus 로고
    • Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3
    • Leung, I.W., and Lassam, N. (1998). Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3. J. Biol. Chem. 273, 32408-32415.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32408-32415
    • Leung, I.W.1    Lassam, N.2
  • 45
    • 0035910529 scopus 로고    scopus 로고
    • The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation
    • Leung, I.W., and Lassam, N. (2001). The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation. J. Biol. Chem. 276, 1961-1967.
    • (2001) J. Biol. Chem. , vol.276 , pp. 1961-1967
    • Leung, I.W.1    Lassam, N.2
  • 46
    • 0028298944 scopus 로고
    • Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: Cloning and characterization of their expression pattern
    • Levedakou, E.N. et al. (1994). Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern. Oncogene 9, 1977-1988.
    • (1994) Oncogene , vol.9 , pp. 1977-1988
    • Levedakou, E.N.1
  • 47
    • 0021919480 scopus 로고
    • Rapid and sensitive protein similarity searches
    • Lipman, D.J., and Pearson, W.R, (1985). Rapid and sensitive protein similarity searches. Science 227, 1435-1441.
    • (1985) Science , vol.227 , pp. 1435-1441
    • Lipman, D.J.1    Pearson, W.R.2
  • 48
    • 0032481104 scopus 로고    scopus 로고
    • The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes
    • Liu, Q., Li, M.Z., Leibham, D., Cortez, D., and Elledge, S.J. (1998). The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes. Curr. Biol. 8, 1300-1309.
    • (1998) Curr. Biol. , vol.8 , pp. 1300-1309
    • Liu, Q.1    Li, M.Z.2    Leibham, D.3    Cortez, D.4    Elledge, S.J.5
  • 49
    • 0029916122 scopus 로고    scopus 로고
    • A human peptidylprolyl isomerase essential for regulation of mitosis
    • Lu, K.P., Hanes, S.D., and Hunter, T. (1996). A human peptidylprolyl isomerase essential for regulation of mitosis. Nature 380, 544-547.
    • (1996) Nature , vol.380 , pp. 544-547
    • Lu, K.P.1    Hanes, S.D.2    Hunter, T.3
  • 50
    • 0029028584 scopus 로고
    • Evidence for a NIMA-like mitotic pathway in vertebrate cells
    • Lu, K.P., and Hunter, T. (1995). Evidence for a NIMA-like mitotic pathway in vertebrate cells. Cell 81, 413-424.
    • (1995) Cell , vol.81 , pp. 413-424
    • Lu, K.P.1    Hunter, T.2
  • 51
    • 0028223346 scopus 로고
    • Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans
    • Lu, K.P., and Means, A.R. (1994). Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans. EMBO J. 13, 2103-2113.
    • (1994) EMBO J. , vol.13 , pp. 2103-2113
    • Lu, K.P.1    Means, A.R.2
  • 52
    • 0030004228 scopus 로고    scopus 로고
    • Prediction and analysis of coiled-coil structures
    • Lupas, A. (1996). Prediction and analysis of coiled-coil structures. Methods Enzymol. 266, 513-525.
    • (1996) Methods Enzymol. , vol.266 , pp. 513-525
    • Lupas, A.1
  • 54
    • 0037089079 scopus 로고    scopus 로고
    • The FA2 gene of Chlamydomonas encodes a NIMA family kinase with roles in cell cycle progression and microtubule severing during deflagellation
    • Mahjoub, M.R., Montpetit, B., Zhao, L., Finst, R.J., Goh, B., Kim, A.C., and Quarmby, L.M. (2002). The FA2 gene of Chlamydomonas encodes a NIMA family kinase with roles in cell cycle progression and microtubule severing during deflagellation. J. Cell Sci. 115, 1759-1768.
    • (2002) J. Cell Sci. , vol.115 , pp. 1759-1768
    • Mahjoub, M.R.1    Montpetit, B.2    Zhao, L.3    Finst, R.J.4    Goh, B.5    Kim, A.C.6    Quarmby, L.M.7
  • 55
    • 0029989288 scopus 로고    scopus 로고
    • Gamma-tubulin in mammalian cells: The centrosomal and the cytosolic forms
    • Moudjou, M., Bordes, N., Paintrand, M., and Bornens, M. (1996). gamma-Tubulin in mammalian cells: the centrosomal and the cytosolic forms. J. Cell Sci. 109, 875-887.
    • (1996) J. Cell Sci. , vol.109 , pp. 875-887
    • Moudjou, M.1    Bordes, N.2    Paintrand, M.3    Bornens, M.4
  • 56
    • 0032472369 scopus 로고    scopus 로고
    • The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3
    • Nagata, K., Puls, A., Futter, C., Aspenstrom, P., Schaefer, E., Nakata, T., Hirokawa, N., and Hall, A. (1998). The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3. EMBO J. 17, 149-158.
    • (1998) EMBO J. , vol.17 , pp. 149-158
    • Nagata, K.1    Puls, A.2    Futter, C.3    Aspenstrom, P.4    Schaefer, E.5    Nakata, T.6    Hirokawa, N.7    Hall, A.8
  • 57
    • 0035796481 scopus 로고    scopus 로고
    • Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components
    • Nihalani, D., Meyer, D., Pajni, S., and Holzman, L.B. (2001). Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components. EMBO J. 20, 3447-3458.
    • (2001) EMBO J. , vol.20 , pp. 3447-3458
    • Nihalani, D.1    Meyer, D.2    Pajni, S.3    Holzman, L.B.4
  • 58
    • 0025246110 scopus 로고
    • Universal control mechanism regulating onset of M-phase
    • Nurse, P. (1990). Universal control mechanism regulating onset of M-phase. Nature 344, 503-508.
    • (1990) Nature , vol.344 , pp. 503-508
    • Nurse, P.1
  • 59
    • 0028080102 scopus 로고
    • Premature chromatin condensation upon accumulation of NIMA
    • O'Connell, M.J., Norbury, C., and Nurse, P. (1994). Premature chromatin condensation upon accumulation of NIMA. EMBO J. 13, 4926-4937.
    • (1994) EMBO J. , vol.13 , pp. 4926-4937
    • O'Connell, M.J.1    Norbury, C.2    Nurse, P.3
  • 60
    • 0020622867 scopus 로고
    • A mutation in Aspergillus nidulans that blocks the transition from interphase to prophase
    • Oakley, B.R., and Morris, N.R. (1983). A mutation in Aspergillus nidulans that blocks the transition from interphase to prophase. J. Cell Biol. 96, 1155-1158.
    • (1983) J. Cell Biol. , vol.96 , pp. 1155-1158
    • Oakley, B.R.1    Morris, N.R.2
  • 61
    • 0026048594 scopus 로고
    • Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans
    • Osmani, A.H., McGuire, S.L., and Osmani, S.A. (1991). Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans. Cell 67, 283-291.
    • (1991) Cell , vol.67 , pp. 283-291
    • Osmani, A.H.1    McGuire, S.L.2    Osmani, S.A.3
  • 62
    • 0023238668 scopus 로고
    • Regulation of the mRNA levels of nimA, a gene required for the G2-M transition in Aspergillus nidulans
    • Osmani, S.A., May, G.S., and Morris, N.R. (1987). Regulation of the mRNA levels of nimA, a gene required for the G2-M transition in Aspergillus nidulans. J. Cell Biol. 104, 1495-1504.
    • (1987) J. Cell Biol. , vol.104 , pp. 1495-1504
    • Osmani, S.A.1    May, G.S.2    Morris, N.R.3
  • 63
    • 0024294395 scopus 로고
    • Mitotic induction and maintenance by overexpression of a G2-specific gene that encodes a potential protein kinase
    • Osmani, S.A., Pu, R.T., and Morris, N.R. (1988). Mitotic induction and maintenance by overexpression of a G2-specific gene that encodes a potential protein kinase. Cell 53, 237-244.
    • (1988) Cell , vol.53 , pp. 237-244
    • Osmani, S.A.1    Pu, R.T.2    Morris, N.R.3
  • 64
    • 0030447537 scopus 로고    scopus 로고
    • Most of centrin in animal cells is not centrosome-associated and centrosomal centrin is confined to the distal lumen of centrioles
    • Paoletti, A., Moudjou, M., Paintrand, M., Salisbury, J.L., and Bornens, M. (1996). Most of centrin in animal cells is not centrosome-associated and centrosomal centrin is confined to the distal lumen of centrioles. J. Cell Sci. 109, 3089-3102.
    • (1996) J. Cell Sci. , vol.109 , pp. 3089-3102
    • Paoletti, A.1    Moudjou, M.2    Paintrand, M.3    Salisbury, J.L.4    Bornens, M.5
  • 65
    • 0031693211 scopus 로고    scopus 로고
    • p21WAF1 is dynamically associated with JNK in human T-lymphocytes during cell cycle progression
    • Patel, R., Bartosch, B., and Blank, J.L. (1998). p21WAF1 is dynamically associated with JNK in human T-lymphocytes during cell cycle progression, J. Cell Sci. 111, 2247-55.
    • (1998) J. Cell Sci. , vol.111 , pp. 2247-2255
    • Patel, R.1    Bartosch, B.2    Blank, J.L.3
  • 66
    • 0023989064 scopus 로고
    • Improved tools for biological sequence comparison
    • Pearson, W.R., and Lipman, D.J. (1988). Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85, 2444-2448.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2444-2448
    • Pearson, W.R.1    Lipman, D.J.2
  • 67
    • 0028910163 scopus 로고
    • Mitotic destruction of the cell cycle regulated NIMA protein kinase of Aspergillus nidulans is required for mitotic exit
    • Pu, R.T., and Osmani, S.A. (1995). Mitotic destruction of the cell cycle regulated NIMA protein kinase of Aspergillus nidulans is required for mitotic exit. EMBO J. 14, 995-1003.
    • (1995) EMBO J. , vol.14 , pp. 995-1003
    • Pu, R.T.1    Osmani, S.A.2
  • 68
    • 0029052804 scopus 로고
    • Isolation of a functional homolog of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans and functional analysis of conserved residues
    • Pu, R.T., Xu, G., Wu, L., Vierula, J., O'Donnell, K., Ye, X.S., and Osmani, S.A. (1995). Isolation of a functional homolog of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans and functional analysis of conserved residues. J. Biol. Chem. 270, 18110-18116.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18110-18116
    • Pu, R.T.1    Xu, G.2    Wu, L.3    Vierula, J.4    O'Donnell, K.5    Ye, X.S.6    Osmani, S.A.7
  • 69
    • 0029760613 scopus 로고    scopus 로고
    • The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1
    • Rana, A., Gallo, K., Godowski, P., Hirai, S., Ohno, S., Zon, L., Kyriakis, J.M., and Avruch, J. (1996). The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1. J. Biol. Chem. 271, 19025-19028.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19025-19028
    • Rana, A.1    Gallo, K.2    Godowski, P.3    Hirai, S.4    Ohno, S.5    Zon, L.6    Kyriakis, J.M.7    Avruch, J.8
  • 70
    • 0030738553 scopus 로고    scopus 로고
    • The NIMA-related kinase 2, Nek2, is expressed in specific stages of the meiotic cell cycle and associates with meiotic chromosomes
    • Rhee, K., and Wolgemuth, D.J. (1997). The NIMA-related kinase 2, Nek2, is expressed in specific stages of the meiotic cell cycle and associates with meiotic chromosomes. Development 124, 2167-2166.
    • (1997) Development , vol.124 , pp. 2167-2166
    • Rhee, K.1    Wolgemuth, D.J.2
  • 71
    • 0022971952 scopus 로고
    • Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
    • Rogers, S., Wells, R., and Rechsteiner, M. (1986). Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science 234, 364-368.
    • (1986) Science , vol.234 , pp. 364-368
    • Rogers, S.1    Wells, R.2    Rechsteiner, M.3
  • 72
    • 0036645394 scopus 로고    scopus 로고
    • Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression
    • Roig, J., Mikhailov, A., Belham, C., and Avruch, J. (2002). Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression. Genes Dev. 16, 1640-1658.
    • (2002) Genes Dev. , vol.16 , pp. 1640-1658
    • Roig, J.1    Mikhailov, A.2    Belham, C.3    Avruch, J.4
  • 73
    • 0028058885 scopus 로고
    • Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans
    • Schultz, S.J., Fry, A.M., Sutterlin, C., Ried, T., and Nigg, E.A. (1994). Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans. Cell Growth Differ. 5, 625-635.
    • (1994) Cell Growth Differ. , vol.5 , pp. 625-635
    • Schultz, S.J.1    Fry, A.M.2    Sutterlin, C.3    Ried, T.4    Nigg, E.A.5
  • 74
    • 0027674809 scopus 로고
    • Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans
    • Schultz, S.J., and Nigg, E.A. (1993). Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans. Cell Growth Differ. 4, 821-930.
    • (1993) Cell Growth Differ. , vol.4 , pp. 821-930
    • Schultz, S.J.1    Nigg, E.A.2
  • 75
    • 0026638996 scopus 로고
    • NPK1, a nonessential protein kinase gene in Saccharomyces cerevisiae with similarity to Aspergillus nidulans nimA
    • Schweitzer, B., and Philippsen, P. (1992). NPK1, a nonessential protein kinase gene in Saccharomyces cerevisiae with similarity to Aspergillus nidulans nimA. Mol. Gen. Genet. 234, 164-167.
    • (1992) Mol. Gen. Genet. , vol.234 , pp. 164-167
    • Schweitzer, B.1    Philippsen, P.2
  • 76
    • 0034721154 scopus 로고    scopus 로고
    • Chfr defines a mitotic stress checkpoint that delays entry into metaphase
    • Scolnick, D.M., and Halazonetis, T.D. (2000). Chfr defines a mitotic stress checkpoint that delays entry into metaphase. Nature 406, 430-435.
    • (2000) Nature , vol.406 , pp. 430-435
    • Scolnick, D.M.1    Halazonetis, T.D.2
  • 77
    • 0033532079 scopus 로고    scopus 로고
    • Cloning and characterization of the murine Nek3 protein kinase, a novel member of the NIMA family of putative cell cycle regulators
    • Tanaka, K., and Nigg, E.A. (1999). Cloning and characterization of the murine Nek3 protein kinase, a novel member of the NIMA family of putative cell cycle regulators. J. Biol. Chem. 274, 13491-13497.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13491-13497
    • Tanaka, K.1    Nigg, E.A.2
  • 78
    • 0029913510 scopus 로고    scopus 로고
    • Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c- Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family
    • Teramoto, H., Coso, O.A., Miyata, H., Igishi, T., Miki, T., and Gutkind, J.S. (1996). Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c- Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family. J. Biol. Chem. 271, 27225-8.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27225-27228
    • Teramoto, H.1    Coso, O.A.2    Miyata, H.3    Igishi, T.4    Miki, T.5    Gutkind, J.S.6
  • 80
    • 0033792092 scopus 로고    scopus 로고
    • Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts
    • Tournebize, R. et al. (2000). Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts. Nat. Cell Biol. 2, 13-19.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 13-19
    • Tournebize, R.1
  • 81
    • 0034623051 scopus 로고    scopus 로고
    • Zipper-mediated oligomerization of the mixed lineage kinase SPRK/MLK-3 is not required for its activation by the GTPase cdc 42 but is necessary for its activation of the JNK pathway. Monomeric SPRK L410P does not catalyze the activating phosphorylation of Thr258 of murine mitogen-activated protein kinase kinase 4
    • Vacratsis, P.O., and Gallo, K.A. (2000). Zipper-mediated oligomerization of the mixed lineage kinase SPRK/MLK-3 is not required for its activation by the GTPase cdc 42 but is necessary for its activation of the JNK pathway. Monomeric SPRK L410P does not catalyze the activating phosphorylation of Thr258 of murine mitogen-activated protein kinase kinase 4. J. Biol. Chem. 275, 27893-27900.
    • (2000) J. Biol. Chem. , vol.275 , pp. 27893-27900
    • Vacratsis, P.O.1    Gallo, K.A.2
  • 82
    • 0028062756 scopus 로고
    • XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover
    • Vasquez, R.J., Gard, D.L., and Cassimeris, L. (1994). XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover. J. Cell Biol. 127, 985-993.
    • (1994) J. Cell Biol. , vol.127 , pp. 985-993
    • Vasquez, R.J.1    Gard, D.L.2    Cassimeris, L.3
  • 84
    • 0030031999 scopus 로고    scopus 로고
    • XKCM1: A Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly
    • Walczak, C.E., Mitchison, T.J., and Desai, A. (1996). XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly. Cell 84, 37-47.
    • (1996) Cell , vol.84 , pp. 37-47
    • Walczak, C.E.1    Mitchison, T.J.2    Desai, A.3
  • 85
    • 0034212385 scopus 로고    scopus 로고
    • Paclitaxel-induced cell death: Where the cell cycle and apoptosis come together
    • Wang, T.H., Wang, H.S., and Soong, Y.K. (2000). Paclitaxel-induced cell death: where the cell cycle and apoptosis come together. Cancer 88, 2619-2628.
    • (2000) Cancer , vol.88 , pp. 2619-2628
    • Wang, T.H.1    Wang, H.S.2    Soong, Y.K.3
  • 86
    • 0032508714 scopus 로고    scopus 로고
    • A mammalian scaffold complex that selectively mediates MAP kinase activation
    • Whitmarsh, A.J., Cavanagh, J., Tournier, C., Yasuda, J., and Davis, R.J. (1998). A mammalian scaffold complex that selectively mediates MAP kinase activation. Science 281, 1671-4.
    • (1998) Science , vol.281 , pp. 1671-1674
    • Whitmarsh, A.J.1    Cavanagh, J.2    Tournier, C.3    Yasuda, J.4    Davis, R.J.5
  • 87
    • 0032422785 scopus 로고    scopus 로고
    • Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals
    • Whitmarsh, A.J., and Davis, R.J. (1998). Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals. Trends Biochem. Sci. 23, 481-485.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 481-485
    • Whitmarsh, A.J.1    Davis, R.J.2
  • 88
    • 0034050649 scopus 로고    scopus 로고
    • Requirement of the prolyl isomerase Pin1 for the replication checkpoint
    • Winkler, K.E., Swenson, K.I., Kornbluth, S., and Means, A.R. (2000). Requirement of the prolyl isomerase Pin1 for the replication checkpoint. Science 287, 1644-1647.
    • (2000) Science , vol.287 , pp. 1644-1647
    • Winkler, K.E.1    Swenson, K.I.2    Kornbluth, S.3    Means, A.R.4
  • 89
  • 90
    • 0028904124 scopus 로고
    • The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: Coordination of two mitosis promoting kinases
    • Ye, X.S., Xu, G., Pu, R.T., Fincher, R.R., McGuire, S.L., Osmani, A.H., and Osmani, S.A. (1995). The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: coordination of two mitosis promoting kinases. EMBO Journal 14, 986-994.
    • (1995) EMBO Journal , vol.14 , pp. 986-994
    • Ye, X.S.1    Xu, G.2    Pu, R.T.3    Fincher, R.R.4    McGuire, S.L.5    Osmani, A.H.6    Osmani, S.A.7
  • 91
    • 0028231706 scopus 로고
    • Quantitative determination of the proportion of microtubule polymer present during the mitosis-interphase transition
    • Zhai, Y., and Borisy, G.G. (1994). Quantitative determination of the proportion of microtubule polymer present during the mitosis-interphase transition. J. Cell Sci. 107, 881-890.
    • (1994) J. Cell Sci. , vol.107 , pp. 881-890
    • Zhai, Y.1    Borisy, G.G.2
  • 92
    • 0029662197 scopus 로고    scopus 로고
    • Microtubule dynamics at the G2/M transition: Abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis
    • Zhai, Y., Kronebusch, P.J., Simon, P.M., and Borisy, G.G. (1996). Microtubule dynamics at the G2/M transition: abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis. J. Cell Biol. 135, 201-214.
    • (1996) J. Cell Biol. , vol.135 , pp. 201-214
    • Zhai, Y.1    Kronebusch, P.J.2    Simon, P.M.3    Borisy, G.G.4
  • 93
    • 0035824535 scopus 로고    scopus 로고
    • Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain
    • Zhang, H., and Gallo, K.A. (2001). Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain. J. Biol. Chem. 276, 45598-45603.
    • (2001) J. Biol. Chem. , vol.276 , pp. 45598-45603
    • Zhang, H.1    Gallo, K.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.