-
1
-
-
0026483281
-
Variations in patterns of DNA damage induced in human colorectal tumour cells by 5-fluorodcoxyuridine: Implications for mechanisms of resistance and cytotoxicity
-
Canman, C. E., Tang, H. Y., Normolle, D. P., Lawrence, T. S. and Maybaum, J. (1992). Variations in patterns of DNA damage induced in human colorectal tumour cells by 5-fluorodcoxyuridine: Implications for mechanisms of resistance and cytotoxicity. Proc. Nat. Acad. Sci. USA 89, 10474-10478.
-
(1992)
Proc. Nat. Acad. Sci. USA
, vol.89
, pp. 10474-10478
-
-
Canman, C.E.1
Tang, H.Y.2
Normolle, D.P.3
Lawrence, T.S.4
Maybaum, J.5
-
2
-
-
0021271862
-
The interleukin-2 cell system: A new cell growth model
-
Cantrell, D. A. and Smith, K. A. (1984) The interleukin-2 cell system: a new cell growth model. Science 224, 1312-1316.
-
(1984)
Science
, vol.224
, pp. 1312-1316
-
-
Cantrell, D.A.1
Smith, K.A.2
-
3
-
-
0029753773
-
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and radiation
-
Chen, Y.-R., Wang, X., Templeton, D., Davis, R. J. and Tan, T-H. (1996) The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and radiation. J. Biol. Chem. 271, 31929-31936.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31929-31936
-
-
Chen, Y.-R.1
Wang, X.2
Templeton, D.3
Davis, R.J.4
Tan, T.-H.5
-
4
-
-
0027485719
-
1/S transition in activated human T-lymphoblasts
-
1/S transition in activated human T-lymphoblasts. J. Biol. Chem. 268, 26144-26149.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26144-26149
-
-
Churcher, Y.1
Moss, S.K.2
-
6
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Derijard, B., Hibi, M., Wu, I.-H., Barett, T., Su, B., Deng, T., Karin, M. and Davis, R. J. (1994). JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.-H.3
Barett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
7
-
-
0030826412
-
A cytoplasmic inhibitor of the JNK signal transduction pathway
-
Dickens, M., Rogers, J. S., Cavanagh, J., Raitano, A., Xia, Z., Halpern, J. R., Greenberg, M. E., Sawyers, C. L. and Davis, R. J. (1997) A cytoplasmic inhibitor of the JNK signal transduction pathway. Science 277, 693-696.
-
(1997)
Science
, vol.277
, pp. 693-696
-
-
Dickens, M.1
Rogers, J.S.2
Cavanagh, J.3
Raitano, A.4
Xia, Z.5
Halpern, J.R.6
Greenberg, M.E.7
Sawyers, C.L.8
Davis, R.J.9
-
9
-
-
0025940709
-
cdc2 tyrosine phosphorylation cycle in early sea urchin embryos
-
cdc2 tyrosine phosphorylation cycle in early sea urchin embryos. EMBO J 10, 3769-3775.
-
(1991)
EMBO J
, vol.10
, pp. 3769-3775
-
-
Edgecombe, M.1
Patel, R.2
Whitaker, M.3
-
10
-
-
0029808466
-
Cell cycle checkpoints: Preventing an identity crisis
-
Elledge, S. J. (1996) Cell cycle checkpoints: preventing an identity crisis. Science 274, 1664-1672.
-
(1996)
Science
, vol.274
, pp. 1664-1672
-
-
Elledge, S.J.1
-
11
-
-
0030746053
-
Hsp70 prevents activation of stress kinases
-
Gabai, V. L., Meriin, A. B., Mosser, D. D., Caron, A. W., Rits, S., Shifrin, V. I. and Sherman, M. Y. (1997). Hsp70 prevents activation of stress kinases. J. Biol. Chem. 272, 18033-18037.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18033-18037
-
-
Gabai, V.L.1
Meriin, A.B.2
Mosser, D.D.3
Caron, A.W.4
Rits, S.5
Shifrin, V.I.6
Sherman, M.Y.7
-
12
-
-
0028905076
-
Transcription factor ATF2 regulation by the Jnk signal transduction pathway
-
Gupta, S., Campbell, D., Derijard, B. and Davis, R. J. (1995). Transcription factor ATF2 regulation by the Jnk signal transduction pathway. Science 267, 389-393.
-
(1995)
Science
, vol.267
, pp. 389-393
-
-
Gupta, S.1
Campbell, D.2
Derijard, B.3
Davis, R.J.4
-
13
-
-
0029885419
-
Selective interaction of JNK protein kinase isoforms with transcription factors
-
Gupta, S., Barrett, T., Whitmarsh, A. J., Cavanagh, J., Sluss, H. K., Derijard, B. and Davis, R. J. (1996) Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J. 15, 2760-2770.
-
(1996)
EMBO J.
, vol.15
, pp. 2760-2770
-
-
Gupta, S.1
Barrett, T.2
Whitmarsh, A.J.3
Cavanagh, J.4
Sluss, H.K.5
Derijard, B.6
Davis, R.J.7
-
14
-
-
0027936755
-
A MAP kinase targeted by endotoxins and hyperosmolarity in mammalian cells
-
Man, J., Lee, J. D., Bibbs, L. and Ulevitch, R. J. (1994) A MAP kinase targeted by endotoxins and hyperosmolarity in mammalian cells. Science 265, 808-811.
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Man, J.1
Lee, J.D.2
Bibbs, L.3
Ulevitch, R.J.4
-
15
-
-
0024425887
-
Checkpoints: Controls that ensure the order of cell cycle events
-
Hartwell, L. and Weinert, T. (1989). Checkpoints: controls that ensure the order of cell cycle events. Science 246, 629-634.
-
(1989)
Science
, vol.246
, pp. 629-634
-
-
Hartwell, L.1
Weinert, T.2
-
16
-
-
0027967944
-
Rules to replicate by
-
Heichman, K. A. and Roberts, J. M. (1994). Rules to replicate by. Cell 79, 557-562.
-
(1994)
Cell
, vol.79
, pp. 557-562
-
-
Heichman, K.A.1
Roberts, J.M.2
-
17
-
-
0027938209
-
Cyclins and cancer II: Cyclin I and CDK inhibitors come of age
-
Hunter, T. and Pines, J. (1994) Cyclins and cancer II: cyclin I) and CDK inhibitors come of age. Cell 79, 573-582.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
18
-
-
0029973389
-
Cell-cycle control and its watchman
-
Jacks, T. and Weinberg, R. A. (1996). Cell-cycle control and its watchman Nature 381, 643-644.
-
(1996)
Nature
, vol.381
, pp. 643-644
-
-
Jacks, T.1
Weinberg, R.A.2
-
19
-
-
0021004695
-
Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA
-
Jackson, R. J. and Hunt, T. (1983). Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA. Meth. Enzymol. 96, 50-74.
-
(1983)
Meth. Enzymol.
, vol.96
, pp. 50-74
-
-
Jackson, R.J.1
Hunt, T.2
-
20
-
-
0026685693
-
I-β-D-arabinosylcytosine and 5-azacytidine induce intranucleosomal DNA fragmentation and cell death in thymocytes
-
Kizaki, H., Ohnishi, Y., Azuma, Y., Mizuno, Y. and Ohsaka, F. (1992) I-β-D-arabinosylcytosine and 5-azacytidine induce intranucleosomal DNA fragmentation and cell death in thymocytes. lmmunopharmacology 24, 219-227.
-
(1992)
Lmmunopharmacology
, vol.24
, pp. 219-227
-
-
Kizaki, H.1
Ohnishi, Y.2
Azuma, Y.3
Mizuno, Y.4
Ohsaka, F.5
-
21
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis, J. M. and Avruch, J. (1996) Sounding the alarm: Protein kinase cascades activated by stress and inflammation. J. Biol. Chem. 271, 24313-24316.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
22
-
-
0024997935
-
Pp54 microtubule-associated protein-2 kinase: A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine
-
Kyriakis, J. M. and Avruch, J. ( 1990). pp54 microtubule-associated protein-2 kinase: A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine. J. Biol. Chem. 265, 17355-17363.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 17355-17363
-
-
Kyriakis, J.M.1
Avruch, J.2
-
23
-
-
0025883213
-
Pp54 microtubule-associated protein-2 kinase requires both tyrosine and serine/threonine phosphorylation for activity
-
Kyriakis, J. M., Brautigan, D. L., Ingebritsen, T. S. and Avruch, J. (1991). pp54 microtubule-associated protein-2 kinase requires both tyrosine and serine/threonine phosphorylation for activity. J. Biol. Chem. 266, 10043-10046.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 10043-10046
-
-
Kyriakis, J.M.1
Brautigan, D.L.2
Ingebritsen, T.S.3
Avruch, J.4
-
24
-
-
0028567864
-
Defects in radiation signal transduction in ataxiatelangiectasia
-
Lavin, M. F., Khanna, K. K., Beamish, H., Teale, B., Hobson, K. and Walters, D. (1994). Defects in radiation signal transduction in ataxiatelangiectasia. Int. J. Rad. Biol. 66, S151-S156.
-
(1994)
Int. J. Rad. Biol.
, vol.66
-
-
Lavin, M.F.1
Khanna, K.K.2
Beamish, H.3
Teale, B.4
Hobson, K.5
Walters, D.6
-
25
-
-
0028800947
-
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
-
Martin, S. J., Reutelingsperger, C. P. M., McGahon, A. J., Rader, J. A., Van Schie, R. C. A. A., LaFace, D. M. and Green, D. R. (1994) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182, 1545-1556.
-
(1994)
J. Exp. Med.
, vol.182
, pp. 1545-1556
-
-
Martin, S.J.1
Reutelingsperger, C.P.M.2
McGahon, A.J.3
Rader, J.A.4
Van Schie, R.C.A.A.5
LaFace, D.M.6
Green, D.R.7
-
26
-
-
0028966941
-
P53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase. JNK1
-
Milne, D. M., Campbell, L. E., Campbell, D. G. and Meek, D. W. (1995) p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase. JNK1. J. Biol. Chem. 270, 5511-5518.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5511-5518
-
-
Milne, D.M.1
Campbell, L.E.2
Campbell, D.G.3
Meek, D.W.4
-
27
-
-
0029070887
-
Selective activation of the JNK signalling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
-
Minden, A., Lin, A., Claret, F-X., Abo, A. and Karin, M. (1995). Selective activation of the JNK signalling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 81, 1147-1157.
-
(1995)
Cell
, vol.81
, pp. 1147-1157
-
-
Minden, A.1
Lin, A.2
Claret, F.-X.3
Abo, A.4
Karin, M.5
-
28
-
-
0030614474
-
12:-induced G1 to S phase cell cycle progression on both Ras/mitogen-activated protein kinase and Ras/Rac/Jun N-terminal kinase cascades in NIH3T3 fibroblasts
-
12:-induced G1 to S phase cell cycle progression on both Ras/mitogen-activated protein kinase and Ras/Rac/Jun N-terminal kinase cascades in NIH3T3 fibroblasts J. Biol. Chem. 272, 4904-1910.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4904-11910
-
-
Mitsui, H.1
Takuwa, N.2
Kurokawa, K.3
Exton, J.H.4
Takuwa, V.5
-
30
-
-
0026757270
-
An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase
-
Mukhopadhyay, N. K., Price, D. J., Kyriakis, J. M., Pelech, S., Sanghera, J. and Avruch, J. (1992) An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase. J. Biol. Chem. 267, 3325-3335.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3325-3335
-
-
Mukhopadhyay, N.K.1
Price, D.J.2
Kyriakis, J.M.3
Pelech, S.4
Sanghera, J.5
Avruch, J.6
-
31
-
-
0026703325
-
Creative blocks: Cell-cycle checkpoints and feedback controls
-
Murray, A. W. (1992). Creative blocks: cell-cycle checkpoints and feedback controls. Nature 359, 599-604.
-
(1992)
Nature
, vol.359
, pp. 599-604
-
-
Murray, A.W.1
-
32
-
-
0028172867
-
klpl cyclin-dependent kinase inhibitor by rapamycin
-
klpl cyclin-dependent kinase inhibitor by rapamycin. Nature 372, 570-573.
-
(1994)
Nature
, vol.372
, pp. 570-573
-
-
Nourse, J.1
Firpo, E.2
Flanagan, W.M.3
Coats, S.4
Polyak, K.5
Lee, M.-H.6
Massague, J.7
Crabtree, G.R.8
Roberts, J.M.9
-
33
-
-
0029101360
-
An essential role for Rho. Rac and Cdc42 GTPases in cell cycle progression through G1
-
Olson, M. F., Ashworth, A. and Hall, A. (1995). An essential role for Rho. Rac and Cdc42 GTPases in cell cycle progression through G1. Science 269, 1270-1272.
-
(1995)
Science
, vol.269
, pp. 1270-1272
-
-
Olson, M.F.1
Ashworth, A.2
Hall, A.3
-
34
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
-
Raingeaud, J., Gupta, S., Rogers, J. S., Dickens, M., Han, J., Ulevitch, R. J. and Davis, R. J. (1995). Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270, 7420-7426.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7420-7426
-
-
Raingeaud, J.1
Gupta, S.2
Rogers, J.S.3
Dickens, M.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
35
-
-
0029589929
-
The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation
-
Raitano, A. B., Halpern, J. R., Hambuch, T. M. and Sawyers, C. L. (1995) The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation. Proc. Nat. Acad. Sci. USA 92, 11746-11750.
-
(1995)
Proc. Nat. Acad. Sci. USA
, vol.92
, pp. 11746-11750
-
-
Raitano, A.B.1
Halpern, J.R.2
Hambuch, T.M.3
Sawyers, C.L.4
-
36
-
-
0028022750
-
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylalion of the small heat shock proteins
-
Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T. and Nebrada, A. (1994). A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylalion of the small heat shock proteins. Cell 78, 1027-1037.
-
(1994)
Cell
, vol.78
, pp. 1027-1037
-
-
Rouse, J.1
Cohen, P.2
Trigon, S.3
Morange, M.4
Alonso-Llamazares, A.5
Zamanillo, D.6
Hunt, T.7
Nebrada, A.8
-
37
-
-
0025950771
-
Mechanism of DNA polymerase alpha inhibition by aphidicolin
-
Sheaff, R., Ilsley, D. and Kutcha, R. (1991). Mechanism of DNA polymerase alpha inhibition by aphidicolin. Biochemistry 30, 8590-8597.
-
(1991)
Biochemistry
, vol.30
, pp. 8590-8597
-
-
Sheaff, R.1
Ilsley, D.2
Kutcha, R.3
-
38
-
-
0029957019
-
A non enzymatic p21 protein inhibitor of stress-activated protein kinases
-
Shim, J., Lee, H., Park, J., Kim, H. and Choi, E-J. (1996). A non enzymatic p21 protein inhibitor of stress-activated protein kinases. Nature 381, 804-807.
-
(1996)
Nature
, vol.381
, pp. 804-807
-
-
Shim, J.1
Lee, H.2
Park, J.3
Kim, H.4
Choi, E.-J.5
-
39
-
-
0026657460
-
Biphasic activation of two mitogen-activated protein kinases during the cell cycle in mammalian cells
-
Tamemoto, H., Kadowaki, T., Tobe, K., Ueki, K., Izumi, T., Chatani, Y., Kohno, M., Kasuga, M., Yazaki, Y. and Akanuma, Y. (1992). Biphasic activation of two mitogen-activated protein kinases during the cell cycle in mammalian cells. J. Biol. Chem 267, 20293-20297.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 20293-20297
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
Ueki, K.4
Izumi, T.5
Chatani, Y.6
Kohno, M.7
Kasuga, M.8
Yazaki, Y.9
Akanuma, Y.10
-
40
-
-
0347537940
-
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
-
Verheij, M., Bose, R., Lin, X. H., Yao, B., Jarvis, W. D., Grant, S., Birrer, M. J., Szabo, E., Zon, L. I., Kyriakis, J. M., Haimovitz-Friedman, A., Fuks, Z. and Kolesnick, R. N. (1996). Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 380, 75-79.
-
(1996)
Nature
, vol.380
, pp. 75-79
-
-
Verheij, M.1
Bose, R.2
Lin, X.H.3
Yao, B.4
Jarvis, W.D.5
Grant, S.6
Birrer, M.J.7
Szabo, E.8
Zon, L.I.9
Kyriakis, J.M.10
Haimovitz-Friedman, A.11
Fuks, Z.12
Kolesnick, R.N.13
-
41
-
-
0030011128
-
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
-
Waldman, T., Lengauer, C., Kinzler, K. W. and Vogelstein, B. (1996) Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381, 713-716.
-
(1996)
Nature
, vol.381
, pp. 713-716
-
-
Waldman, T.1
Lengauer, C.2
Kinzler, K.W.3
Vogelstein, B.4
-
42
-
-
0029125757
-
Integration of MAP kinase signal transduction pathways at the serum response element
-
Whitmarsh, A. J., Shore, P., Sharrocks, A. D. and Davis, R. J. (1995). Integration of MAP kinase signal transduction pathways at the serum response element Science 269, 403-407.
-
(1995)
Science
, vol.269
, pp. 403-407
-
-
Whitmarsh, A.J.1
Shore, P.2
Sharrocks, A.D.3
Davis, R.J.4
-
43
-
-
0029906759
-
The stress activated protein kinase pathway
-
Woodgett, J. R., Avruch, J. and Kyriakis, J. (1996). The stress activated protein kinase pathway. Cancer Surveys 27, 127-138.
-
(1996)
Cancer Surveys
, vol.27
, pp. 127-138
-
-
Woodgett, J.R.1
Avruch, J.2
Kyriakis, J.3
-
44
-
-
0011980938
-
ADP-ribosylation of the rhoA gene product by botulinum C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle
-
Yamamoto, M., Marui, N., Sakai, T., Morii, N., Kozaki, S., Ikai, K., Imamura, S. and Narumiya, S. (1993). ADP-ribosylation of the rhoA gene product by botulinum C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle. J. Biol. Chem. 268, 21509-21512.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21509-21512
-
-
Yamamoto, M.1
Marui, N.2
Sakai, T.3
Morii, N.4
Kozaki, S.5
Ikai, K.6
Imamura, S.7
Narumiya, S.8
-
45
-
-
0030272630
-
Adriamycin activates c-Jun N-terminal kinase in human leukemia cells: A relevance to apoptosis
-
Yu, R., Shtil, A. A., Tan, T-H., Roninson, I. B. and Kong, A-N, T. (1996). Adriamycin activates c-Jun N-terminal kinase in human leukemia cells: A relevance to apoptosis. Cancer Lett. 107, 73-81.
-
(1996)
Cancer Lett.
, vol.107
, pp. 73-81
-
-
Yu, R.1
Shtil, A.A.2
Tan, T.-H.3
Roninson, I.B.4
Kong, A.-N.T.5
-
46
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J. and Greenberg, M. E. (1995). Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Science 270, 1326-1331
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
|