메뉴 건너뛰기




Volumn 170, Issue 1, 2003, Pages 300-307

Activated STAT4 and a functional role for IL-12 in human Peyer's patches

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; NUCLEAR PROTEIN; RECEPTOR SUBUNIT; STAPHYLOCOCCUS ENTEROTOXIN B; STAT4 PROTEIN;

EID: 0037222550     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.1.300     Document Type: Article
Times cited : (19)

References (56)
  • 1
    • 0025127277 scopus 로고
    • Immunomorphological characteristics of human Peyer's patches
    • Brandtzaeg, P., and K. Bjerke. 1990. Immunomorphological characteristics of human Peyer's patches. Digestion 46(Suppl. 2):262.
    • (1990) Digestion , vol.46 , Issue.SUPPL. 2 , pp. 262
    • Brandtzaeg, P.1    Bjerke, K.2
  • 2
    • 0000980950 scopus 로고
    • Number, size and distribution of Peyer's patches in the human small intestine
    • Comes, J. S. 1965. Number, size and distribution of Peyer's patches in the human small intestine. Gut 6:225.
    • (1965) Gut , vol.6 , pp. 225
    • Comes, J.S.1
  • 3
    • 0032403091 scopus 로고    scopus 로고
    • T cell immunity to oral allergens
    • MacDonald, T. T. 1998. T cell immunity to oral allergens. Curr. Opin. Immunol. 10:620.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 620
    • MacDonald, T.T.1
  • 4
    • 0030847054 scopus 로고    scopus 로고
    • Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
    • Weiner, H. L. 1997. Oral tolerance: Immune mechanisms and treatment of autoimmune diseases. Immunol. Today 18:335.
    • (1997) Immunol. Today , vol.18 , pp. 335
    • Weiner, H.L.1
  • 5
    • 0031966706 scopus 로고    scopus 로고
    • Immune responses to dietary antigens: Oral tolerance
    • Strobel, S., and A. M. Mowat. 1998. Immune responses to dietary antigens: Oral tolerance. Immunol. Today. 19:173.
    • (1998) Immunol. Today. , vol.19 , pp. 173
    • Strobel, S.1    Mowat, A.M.2
  • 7
    • 0344848755 scopus 로고    scopus 로고
    • Oral tolerance with an HLA-peptide mimicking retinal autoantigen as a treatment of autoimmune uveitis
    • Thurau, S. R., M. Diedrichs-Mohring, H. Fricke, C. Burchardi, and G. Wildner. 1999. Oral tolerance with an HLA-peptide mimicking retinal autoantigen as a treatment of autoimmune uveitis. Immunol. Lett. 68:205.
    • (1999) Immunol. Lett. , vol.68 , pp. 205
    • Thurau, S.R.1    Diedrichs-Mohring, M.2    Fricke, H.3    Burchardi, C.4    Wildner, G.5
  • 9
    • 0028358048 scopus 로고
    • Induction of anergy or active suppression following oral tolerance is determined by antigen dosage
    • Friedman, A., and H. L. Weiner. 1994. Induction of anergy or active suppression following oral tolerance is determined by antigen dosage. Proc. Natl. Acad. Sci. USA 91:6688.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6688
    • Friedman, A.1    Weiner, H.L.2
  • 10
    • 0027941138 scopus 로고
    • Oral tolerance to MBP induces regulatory TGFβ secreting T cells in Peyer's patches of SJL mice
    • Santos, L. M., A. al-Sabbagh, A. Londono, and H. L. Weiner. 1994. Oral tolerance to MBP induces regulatory TGFβ secreting T cells in Peyer's patches of SJL mice. Cell. Immunol. 157:439.
    • (1994) Cell. Immunol. , vol.157 , pp. 439
    • Santos, L.M.1    Al-Sabbagh, A.2    Londono, A.3    Weiner, H.L.4
  • 11
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differntial upregulation of transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain
    • Khoury, S. J., W. W. Hancock, and H. L. Weiner. 1992. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differntial upregulation of transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain. J. Exp. Med. 176:1355.
    • (1992) J. Exp. Med. , vol.176 , pp. 1355
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 12
    • 0030035509 scopus 로고    scopus 로고
    • Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor β-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients
    • Fukaura, H., S. C. Kent, M. J. Pietrusewicz, S. J. Khoury, H. L. Weiner, and D. A. Hafler. 1996. Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor β-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients. J. Clin. Invest. 98:70.
    • (1996) J. Clin. Invest. , vol.98 , pp. 70
    • Fukaura, H.1    Kent, S.C.2    Pietrusewicz, M.J.3    Khoury, S.J.4    Weiner, H.L.5    Hafler, D.A.6
  • 13
    • 0026048323 scopus 로고
    • The in vitro production of cytokines by mucosal lymphocytes immunized by oral administration of keyhole limpet hemocyanin using cholera toxin as an adjuvant
    • Wilson, A. D., M. Bailey, N. A. Williams, and C. R. Stokes. 1991. The in vitro production of cytokines by mucosal lymphocytes immunized by oral administration of keyhole limpet hemocyanin using cholera toxin as an adjuvant. Eur. J. Immunol. 21:2333.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2333
    • Wilson, A.D.1    Bailey, M.2    Williams, N.A.3    Stokes, C.R.4
  • 14
    • 0027183310 scopus 로고
    • Helper T cell subsets for immunoglobulin A responses: Oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues
    • Xu-Amano, J., H. Kiyono, R. J. Jackson, H. F. Staats, K. Fujihashi, P. D. Burrows, C. O. Elson, S. Pillai, and J. R. McGhee. 1993. Helper T cell subsets for immunoglobulin A responses: Oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. J. Exp. Med. 178:1309.
    • (1993) J. Exp. Med. , vol.178 , pp. 1309
    • Xu-Amano, J.1    Kiyono, H.2    Jackson, R.J.3    Staats, H.F.4    Fujihashi, K.5    Burrows, P.D.6    Elson, C.O.7    Pillai, S.8    McGhee, J.R.9
  • 15
    • 0030587132 scopus 로고    scopus 로고
    • High dose oral tolerance in ovalbumin TCR-transgenic mice: Systemic neutralization of IL-12 augments TGF-β secretion and T cell apoptosis
    • Marth, T., W. Strober, and B. L. Kelsall. 1996. High dose oral tolerance in ovalbumin TCR-transgenic mice: Systemic neutralization of IL-12 augments TGF-β secretion and T cell apoptosis. J. Immunol. 157:2348.
    • (1996) J. Immunol. , vol.157 , pp. 2348
    • Marth, T.1    Strober, W.2    Kelsall, B.L.3
  • 16
    • 0030938148 scopus 로고    scopus 로고
    • Regulation of transforming growth factor-β production by interleukin-12
    • Marth, T., W. Strober, R. A. Seder, and B. L. Kelsall. 1997. Regulation of transforming growth factor-β production by interleukin-12. Eur. J. Immunol. 27:1213.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1213
    • Marth, T.1    Strober, W.2    Seder, R.A.3    Kelsall, B.L.4
  • 17
    • 0034665313 scopus 로고    scopus 로고
    • An intra-Peyer's patch gene transfer model for studying mucosal tolerance: Distinct roles of B7 and IL-12 in mucosal T cell tolerance
    • Chen, Y., K. Song, S. L. Eck, and Y. Chen. 2000. An intra-Peyer's patch gene transfer model for studying mucosal tolerance: Distinct roles of B7 and IL-12 in mucosal T cell tolerance. J. Immunol. 165:3145.
    • (2000) J. Immunol. , vol.165 , pp. 3145
    • Chen, Y.1    Song, K.2    Eck, S.L.3    Chen, Y.4
  • 18
    • 0032146680 scopus 로고    scopus 로고
    • An analysis of interferon γ, IL-4, IL-5 and IL-10 productions by ELISPOT and quantitative reverse transcriptase-PCR in human Peyer's patches
    • Hauer, A. C., M. Bajaj-Elliott, C. B. Williams, J. A. Walker-Smith, and T. T. MacDonald. 1998. An analysis of interferon γ, IL-4, IL-5 and IL-10 productions by ELISPOT and quantitative reverse transcriptase-PCR in human Peyer's patches. Cytokine 10:627.
    • (1998) Cytokine , vol.10 , pp. 627
    • Hauer, A.C.1    Bajaj-Elliott, M.2    Williams, C.B.3    Walker-Smith, J.A.4    MacDonald, T.T.5
  • 23
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787.
    • (1996) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 24
    • 0028043326 scopus 로고
    • Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
    • Trinchieri, G. 1994. Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes. Blood 84:4006.
    • (1994) Blood , vol.84 , pp. 4006
    • Trinchieri, G.1
  • 26
    • 0031568526 scopus 로고    scopus 로고
    • IFN-γ-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12
    • Kohno, K., J. Kataoka, T. Ohtsuki, Y. Suemoto, I. Okamoto, M. Usui, M. Ikeda, and M. Kurimoto. 1997. IFN-γ-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J. Immunol. 158:1541.
    • (1997) J. Immunol. , vol.158 , pp. 1541
    • Kohno, K.1    Kataoka, J.2    Ohtsuki, T.3    Suemoto, Y.4    Okamoto, I.5    Usui, M.6    Ikeda, M.7    Kurimoto, M.8
  • 29
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12Rβ2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • Szabo, S. J., A. S. Dighe, U. Gubler, and K. M. Murphy. 1997. Regulation of the interleukin (IL)-12Rβ2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 185:817.
    • (1997) J. Exp. Med. , vol.185 , pp. 817
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 31
    • 0033560023 scopus 로고    scopus 로고
    • Regulation of interleukin (IL)-12 receptor β2 subunit expression by endogenous IL-12: A critical step in the differentiation of pathogenic autoreactive T cells
    • Chang, J. T., E. M. Shevach, and B. M. Segal. 1999. Regulation of interleukin (IL)-12 receptor β2 subunit expression by endogenous IL-12: A critical step in the differentiation of pathogenic autoreactive T cells. J. Exp. Med. 189:969.
    • (1999) J. Exp. Med. , vol.189 , pp. 969
    • Chang, J.T.1    Shevach, E.M.2    Segal, B.M.3
  • 32
    • 0033215166 scopus 로고    scopus 로고
    • Depressed IL-12-mediated signal transduction in T cells from patients with Sezary syndrome is associated with the absence of IL-12 receptor β2 mRNA and highly reduced levels of STAT4
    • Showe, L. C., F. E. Fox, D. Williams, K. Au, Z. Niu, and A. H. Rook. 1999. Depressed IL-12-mediated signal transduction in T cells from patients with Sezary syndrome is associated with the absence of IL-12 receptor β2 mRNA and highly reduced levels of STAT4. J. Immunol. 163:4073.
    • (1999) J. Immunol. , vol.163 , pp. 4073
    • Showe, L.C.1    Fox, F.E.2    Williams, D.3    Au, K.4    Niu, Z.5    Rook, A.H.6
  • 34
    • 0033558107 scopus 로고    scopus 로고
    • Expression of the IL-12 receptor β1 and β2 subunits in human tuberculosis
    • Zhang, M., J. Gong, D. H. Presky, W. Xue, and P. F. Barnes. 1999. Expression of the IL-12 receptor β1 and β2 subunits in human tuberculosis. J. Immunol. 162:2441.
    • (1999) J. Immunol. , vol.162 , pp. 2441
    • Zhang, M.1    Gong, J.2    Presky, D.H.3    Xue, W.4    Barnes, P.F.5
  • 36
    • 0030046753 scopus 로고    scopus 로고
    • STATs: Signal transducers and activators of transcription
    • Ihle, J. N. 1996. STATs: Signal transducers and activators of transcription. Cell 84:331.
    • (1996) Cell , vol.84 , pp. 331
    • Ihle, J.N.1
  • 38
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    • Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity. 4:313.
    • (1996) Immunity , vol.4 , pp. 313
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 39
  • 40
    • 0034571173 scopus 로고    scopus 로고
    • The molecular basis of T helper 1 and T helper 2 cell differentiation
    • O'Garra, A., and N. Arai. 2000. The molecular basis of T helper 1 and T helper 2 cell differentiation. Trends Cell. Biol. 10:542.
    • (2000) Trends Cell. Biol. , vol.10 , pp. 542
    • O'Garra, A.1    Arai, N.2
  • 44
    • 0035070195 scopus 로고    scopus 로고
    • Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets
    • Grogan, J. L., M. Mohrs, B. Harmon, D. A. Dacy, J. W. Sedat, and L. M. Locksley. 2001. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity. 14:205.
    • (2001) Immunity , vol.14 , pp. 205
    • Grogan, J.L.1    Mohrs, M.2    Harmon, B.3    Dacy, D.A.4    Sedat, J.W.5    Locksley, L.M.6
  • 46
    • 0030209985 scopus 로고    scopus 로고
    • + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease: Crohn's disease LP cells manifest increased secretion of IFN-γ whereas ulcerative colitis LP cells manifest increased secretion of IL-5
    • + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease: Crohn's disease LP cells manifest increased secretion of IFN-γ whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J. Immunol. 157:1261.
    • (1996) J. Immunol. , vol.157 , pp. 1261
    • Fuss, I.J.1    Neurath, M.2    Boirivant, M.3    Klein, J.S.4    De la Motte, C.5    Strong, S.A.6    Fiocchi, C.7    Strober, W.8
  • 47
    • 0030728570 scopus 로고    scopus 로고
    • The frequency of cells secreting interferon-γ and interleukin-4, -5 and -10 in the blood and duodenal mucosa of children with cow's milk hypersensitivity
    • Hauer, A. C., E. J. Breese, J. A. Walker-Smith, and T. T. MacDonald. 1997. The frequency of cells secreting interferon-γ and interleukin-4, -5 and -10 in the blood and duodenal mucosa of children with cow's milk hypersensitivity. Pediatr. Res. 42:629.
    • (1997) Pediatr. Res. , vol.42 , pp. 629
    • Hauer, A.C.1    Breese, E.J.2    Walker-Smith, J.A.3    MacDonald, T.T.4
  • 48
    • 0031864836 scopus 로고    scopus 로고
    • Spontaneous secretion of interferon γ and interleukin 4 by human intraepithelial and lamina propria gut lymphocytes
    • Carol, M., A. Lambrechts, A. Van Gossum, M. Libin, M. Goldman, and F. Mascart-Lemone. 1998. Spontaneous secretion of interferon γ and interleukin 4 by human intraepithelial and lamina propria gut lymphocytes. Gut 42:643.
    • (1998) Gut , vol.42 , pp. 643
    • Carol, M.1    Lambrechts, A.2    Van Gossum, A.3    Libin, M.4    Goldman, M.5    Mascart-Lemone, F.6
  • 50
    • 0033564668 scopus 로고    scopus 로고
    • Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells
    • Marth, T., M. Zeitz, B. R. Ludviksson, W. Strober, and B. L. Kelsall. 1999. Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells. J. Immunol. 162:7233.
    • (1999) J. Immunol. , vol.162 , pp. 7233
    • Marth, T.1    Zeitz, M.2    Ludviksson, B.R.3    Strober, W.4    Kelsall, B.L.5
  • 51
    • 0034529318 scopus 로고    scopus 로고
    • Antigen-induced mucosal T cell activation is followed by Th1 T cell suppression in continuously fed ovalbumin TCR-transgenic mice
    • Marth, T., S. Ring, D. Schulte, N. Klensch, W. Strober, B. L. Kelsall, A. Stallmach, and M. Zeitz. 2000. Antigen-induced mucosal T cell activation is followed by Th1 T cell suppression in continuously fed ovalbumin TCR-transgenic mice. Eur. J. Immunol. 30:3478.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3478
    • Marth, T.1    Ring, S.2    Schulte, D.3    Klensch, N.4    Strober, W.5    Kelsall, B.L.6    Stallmach, A.7    Zeitz, M.8
  • 54
    • 0034948805 scopus 로고    scopus 로고
    • Regulation of life and death in lamina propria T cells
    • Levine, A. D., and C. Fiocchi. 2001. Regulation of life and death in lamina propria T cells. Semin. Immunol. 13:195.
    • (2001) Semin. Immunol. , vol.13 , pp. 195
    • Levine, A.D.1    Fiocchi, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.