An analysis of interferon γ, IL-4, IL-5 and IL-10 production by ELISPOT and quantitative reverse transcriptase-PCR in human Peyer's patches

Cytokine

Volumn 10, Issue 8, 1998, Pages 627-634

  Hauer, A Christina ^a   Bajaj Elliott, Mona ^a   Williams, Christopher B ^a   Walker Smith, John A ^a   MacDonald, Thomas T ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Cytokines; Human; Mucosa; Peyer's patch; T lymphocytes

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA;

ARTICLE; CELL SECRETION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; LAMINA PROPRIA; LYMPHOCYTE; MONONUCLEAR CELL; PEYER PATCH; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032146680     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1997.0337     Document Type: Article

References (29)

1. 1. Cebra JJ, Shroff K (1994) Peyer's patches as inductive sites for IgA commitment. In: Ogra PL, Lamm ME, McGhee JR, Mestecky J, Strober W, Bienenstock J. Handbook of Musosal Immunology, Academic Press, San Diego, pp. 151-158.
2. 2. Kato T, Owen RL (1994) Structure and function of intestinal mucosal epithelium. In: Ogra PL, Lamm ME, McGhee JR, Mestecky J, Strober W, Bienenstock J. Handbook of Mucosal Immunology, Academic Press, San Diego, pp. 11-26.
3. 3. Spencer J, Finn T, Isaacson PG (1986) Human Peyer's patches, an immunohistochemical study. Gut 27:405-410.
4. 4. Dogan A, Dunn-Walters D, MacDonald TT, Spencer J (1996) Demonstration of local clonality of mucosal T cells in human colon using DNA obtained by microdissection of immunohistochemically stained tissue sections. Eur J Immunol 26:1240-1245.
5. 5. Craig SW, Cebra JJ (1971) Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit. J Exp Med 134:188-200.
6. 6. Guy-Grand D, Griscelli C, Vassalli P (1978) The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions. J Exp Med 148:1661-1667.
7. 7. Mowat AM (1987) The regulation of immune responses to dietary protein antigens. Immunol Today 8:93-98.
8. 8. Weiner HL (1996) Oral tolerance: immunologic mechanisms and treatment of autoimmune diseases. In: Kagnoff MF, Kiyono H, (eds), Essentials of Mucosal Immunity, Academic Press, San Diego, pp. 555-561.
9. 9. Xu-Amanu J, Kiyono H, Jackson RJ, Staats HF, Fujihashi K, Burrows PD, Elson CO, Pillai S, McGhee JR (1993) Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. J Exp Med 178:1309-1320.
10. 10. Marinaro M, Staats HF, Hiroi T, Jackson RJ, Coste M, Boyaka PN, Okahashi N, Yamamoto M, Kiyono H, Bluethmann H, Fujihashi K, McGhee JR (1995) Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4. J Immunol 155:4621-4629.
11. 11. Coffman RL, Schrader B, Carty J, Mosmann TR, Bond MW (1987) A mouse T cell product that preferentially enhances IgA production. 1. Biologic characterization. J Immunol 139:3685-3696.
12. 12. Taguchi T, McGhee JR, Coffman RL, Beagley KW, Eldridge JH, Takatsu K, Kiyono H (1990) Analysis of Th1 and Th2 cells in murine gut-associated tissues. Frequencies of CD4+ and CD8+ T cells that secrete IFN-γ and IL-5. J Immunol 145:68-77.
13. 13. Wilson AD, Bailey M, Williams NA, Stokes CR (1991) The in vitro production of cytokines by mucosal lymphocytes immunized by oral administration of keyhole limpet hemocyanin using cholera toxin as an adjuvant. Eur J Immunol 21:2333-2339.
14. 14. Cornes JS (1965) Number, size, and distribution of Peyer's patches in the human small intestine. Part 2. The effect of age on Peyer's patches. Gut 6:230-233.
15. 15. Lundqvist C, Melgar S, Yeung MM-W, Hammarstrom S, Hammarstrom M-L (1996) Intraepithelial lymphocytes in human gut have lytic potential and a cytokine profile that suggests T helper 1 and cytotoxic functions. J Immunol 157:1926-1934.
16. 16. Hauer AC, Breese EJ, Walker-Smith JA, MacDonald TT (1997) The frequency of cells secreting interferon-γ, IL-4, IL-5 and IL-10 in the blood and jejunal mucosa of children with cows' milk hypersensitivity. Fed Res 42:629-638.
17. 17. Bradding P, Feather IH, Howarth PH, Mueller R, Roberts JA, Britten K, Bews JP, Hunt TC, Okayama Y, Heusser CH, Bullock GR, Church MK, Holgate ST (1992) Interleukin-4 is localized to and released by human mast cells. J Exp Med 176:1381-1386.
18. 18. Nonaka M, Nonaka R, Woolley K, Adelroth E, Miura K, Okhawara Y, Glibetic M, Nakano K, O'Byrne P, Dolovich J, Jordana M, et al (1995) Distinct immunohistochemical localization of IL-4 in human inflamed airway tissues. IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils. J Immunol 155:3234-3244.
19. 19. Schieferdecker HL, Ullrich R, Hirseland H, Zeitz M (1992) T cell differentiation antigens on lymphocytes in the human intestinal lamina propria. J Immunol 149:2816-2822.
20. 20. DeMaria R, Fais S, Silvestri M, Frati L, Pallone F, Santoni A, Testi R (1993) Continuous in-vivo activation and transient hyporesponsiveness to TcR/CD3 triggering of human gut lamina propria lymphocytes. Eur J Immunol 23:3104-3108.
21. 21. MacDonald TT, Spencer J, Viney JL, Williams CB, Walker-Smith JA (1987) Selective biopsy of human Peyer's patches during ileal endoscopy.Gastroenterology 93:1356-1362.
22. 22. Wallaert B, Desreumaux P, Copin MC, Tillie I, Benard A, Colombel JF, Gossellin B, Tonnel AB, Janin A (1995) Immunoreactivity for interleukin 3 and 5 and granulocyte/macrophage colony-stimulating factor of intestinal mucosa in bronchila asthma. J Exp Med 182:1897-1904.
23. 23. Desreumaux P, Bloget F, Seguy D, Capron M, Cortot A, Colombel JF, Janin A (1996) Interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 in eosinophilic gastroenteritis. Gastroenterology 110:768-774.
24. 24. Fuss IJ, Neurath M, Boirivant M, Klein JS, de la Motte C, Strong SA, Fiocchi C, Strober W (1996) Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 157:1261-1270.
25. 25. Nilsen EM, Lundin KEA, Krajci P, Scott H, Sollid LM, Brandtzaeg P (1995) Gluten-specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon-γ. Gut 37:766-776.
26. 26. Quiding M, Nordstrom I, Kilander A, Andersson G, Hanson LA, Holmgren J, Czerkinsky C (1991) Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local imunological memory. J Clin Invest 88:143-148.
27. 27. Isaacson PG, Wright DH (1986) Immunocytochemistry of lymphoreticular tumours. In: Polak J, van Noorden S, (eds), Immunocytochemistry. Practical Applications in Pathology and Biology. John Wright and Sons. Bristol, pp. 568-598.
28. 28. Bungre J, Till SJ, Larche M, Humbert M, Robinson D, Huston D, Dickason R, Kay AB, Corrigan CP (1996) IL-5 secretion by allergen-specific CD4+ cells in short-term culture: dissociation from allergen-induced proliferation and dependence on B7-2 costimulation. J Allergy Clin Immunol 97:359-365.
29. 29. Jung HC, Eckmann L, Yang SK, Panja A, Fierer J, Morzycka Wroblewska E, Kagnoff MF (1995) A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest 95:55-65.