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Volumn 120, Issue 1, 2003, Pages 107-116

Transdifferentiation of pancreas to liver

Author keywords

C enhancer binding protein; Glucocorticoids; Liver; Metaplasia; Pancreas; PDX 1; Transdifferentiation

Indexed keywords

BINDING PROTEIN; GLUCOCORTICOID; HEPATOCYTE NUCLEAR FACTOR 3; HEPATOCYTE NUCLEAR FACTOR 4; ISOPROTEIN; KERATINOCYTE GROWTH FACTOR; MESSENGER RNA; NUCLEAR FACTOR I; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CCAAT ENHANCER BINDING PROTEIN; DNA BINDING PROTEIN; MLX PROTEIN, HUMAN; PHOSPHOPROTEIN; TRANSCRIPTION FACTOR;

EID: 0037213612     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(02)00337-4     Document Type: Review
Times cited : (108)

References (90)
  • 1
    • 0032525981 scopus 로고    scopus 로고
    • Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
    • Ahlgren U., Jonsson J., Jonsson L., Simu K., Edlund H. Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev. 12:1998;1763-1768.
    • (1998) Genes Dev. , vol.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5
  • 2
    • 0031773563 scopus 로고    scopus 로고
    • Liver stem cells: A two compartment system
    • Alison M. Liver stem cells: a two compartment system. Curr. Opin. Cell Biol. 10:1998;710-715.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 710-715
    • Alison, M.1
  • 4
    • 0017707035 scopus 로고
    • Differentiation of lens and pigment cells in cultures of neural retinal cells of early chick embryos
    • Araki M., Okada T.S. Differentiation of lens and pigment cells in cultures of neural retinal cells of early chick embryos. Dev. Biol. 60:1977;278-286.
    • (1977) Dev. Biol. , vol.60 , pp. 278-286
    • Araki, M.1    Okada, T.S.2
  • 6
    • 0025317804 scopus 로고
    • Direct transdifferentiation: Can cells change their phenotype without dividing?
    • Beresford W.A. Direct transdifferentiation: can cells change their phenotype without dividing? Cell Differ Dev. 29:1990;81-93.
    • (1990) Cell Differ Dev. , vol.29 , pp. 81-93
    • Beresford, W.A.1
  • 7
    • 0031080308 scopus 로고    scopus 로고
    • In vivo footprinting with limiting amounts of embryo tissues: A role for C/EBP beta in early hepatic development
    • Bossard P., McPherson C.E., Zaret K.S. In vivo footprinting with limiting amounts of embryo tissues: a role for C/EBP beta in early hepatic development. Methods. 11:1997;180-188.
    • (1997) Methods , vol.11 , pp. 180-188
    • Bossard, P.1    McPherson, C.E.2    Zaret, K.S.3
  • 8
    • 0029962261 scopus 로고    scopus 로고
    • Liver-enriched transcription factors and hepatocyte differentiation
    • Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation. FASEB J. 10:1996;267-282.
    • (1996) FASEB J. , vol.10 , pp. 267-282
    • Cereghini, S.1
  • 9
    • 0023841285 scopus 로고
    • Regulation of rat liver maturation in vitro by glucocorticoids
    • Chou J.Y., Wan Y.-J.Y., Sakiyama T. Regulation of rat liver maturation in vitro by glucocorticoids. Mol. Cell Biol. 8:1988;203-209.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 203-209
    • Chou, J.Y.1    Wan, Y.-J.Y.2    Sakiyama, T.3
  • 10
    • 0028340889 scopus 로고
    • Pancreatic tumoral cell line AR42J: An amphicrine model
    • Christophe J. Pancreatic tumoral cell line AR42J: an amphicrine model. Am. J. Physiol. 266:1994;G963-G971.
    • (1994) Am. J. Physiol. , vol.266 , pp. 963-G971
    • Christophe, J.1
  • 11
    • 0033453239 scopus 로고    scopus 로고
    • Attenuation of green fluorescent protein half-like in mammalian cells
    • Corish P., Tyler-Smith C. Attenuation of green fluorescent protein half-like in mammalian cells. Protein Eng. 12:1999;1035-1040.
    • (1999) Protein Eng. , vol.12 , pp. 1035-1040
    • Corish, P.1    Tyler-Smith, C.2
  • 12
    • 0028892856 scopus 로고
    • Transcription factor and liver-specific mRNA expression in facultative epithelial progenitor cells of liver and pancreas
    • Dabeva M.D., Hurston E., Sharitz D.A. Transcription factor and liver-specific mRNA expression in facultative epithelial progenitor cells of liver and pancreas. Am. J. Pathol. 147:1995;1633-1648.
    • (1995) Am. J. Pathol. , vol.147 , pp. 1633-1648
    • Dabeva, M.D.1    Hurston, E.2    Sharitz, D.A.3
  • 14
    • 0032515065 scopus 로고    scopus 로고
    • The role of C/EBP genes in adipocyte differentiation
    • Darlington G.J., Ross S.E., MacDougald O.A. The role of C/EBP genes in adipocyte differentiation. J Biol. Chem. 273:1998;30057-30060.
    • (1998) J Biol. Chem. , vol.273 , pp. 30057-30060
    • Darlington, G.J.1    Ross, S.E.2    MacDougald, O.A.3
  • 15
    • 0025936177 scopus 로고
    • Liver-enriched and transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA
    • Descombes P., Schibler U.A. Liver-enriched and transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell. 67:1991;569-579.
    • (1991) Cell , vol.67 , pp. 569-579
    • Descombes, P.1    Schibler, U.A.2
  • 16
    • 0035072545 scopus 로고    scopus 로고
    • A bipotential precursor population for pancreas and liver within the embryonic endoderm
    • Deutsch G., Jung J., Zheng M., Lora J., Zaret K.S. A bipotential precursor population for pancreas and liver within the embryonic endoderm. Development. 128:2001;871-881.
    • (2001) Development , vol.128 , pp. 871-881
    • Deutsch, G.1    Jung, J.2    Zheng, M.3    Lora, J.4    Zaret, K.S.5
  • 17
    • 0032553315 scopus 로고    scopus 로고
    • Role of CCAAT/enhancer binding proteins in regulation of liver regenerative growth
    • Diehl A.M. Role of CCAAT/enhancer binding proteins in regulation of liver regenerative growth. J. Biol. Chem. 273:1998;30843-40846.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30843-40846
    • Diehl, A.M.1
  • 19
    • 0015788201 scopus 로고
    • Differentiation of lens tissue from the progeny of chick retinal pigment cells cultured in vitro: A demonstration of a switch of cell types in clonal cell culture
    • Eguchi G., Okada T.S. Differentiation of lens tissue from the progeny of chick retinal pigment cells cultured in vitro: a demonstration of a switch of cell types in clonal cell culture. Proc. Natl. Acad. Sci. USA. 70:1973;1495-1499.
    • (1973) Proc. Natl. Acad. Sci. USA , vol.70 , pp. 1495-1499
    • Eguchi, G.1    Okada, T.S.2
  • 20
    • 0001007689 scopus 로고
    • Introduction: Transdifferentiation
    • Eguchi G. Introduction: transdifferentiation. Semin. Cell Biol. 6:1995;105-108.
    • (1995) Semin. Cell Biol. , vol.6 , pp. 105-108
    • Eguchi, G.1
  • 21
    • 0026742624 scopus 로고
    • Hepatocyte nuclear factor 1α is expressed in a hamster insulinoma line and transactivates the rat insulin I gene
    • Emens L.A., Landers D.W., Moss L.G. Hepatocyte nuclear factor 1α is expressed in a hamster insulinoma line and transactivates the rat insulin I gene. Proc. Natl. Acad. Sci. USA. 89:1992;7300-7304.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7300-7304
    • Emens, L.A.1    Landers, D.W.2    Moss, L.G.3
  • 23
    • 0035545794 scopus 로고    scopus 로고
    • Stem cells: Is there a future in plastic?
    • Goodell M.A. Stem cells: is there a future in plastic? Curr. Opin. Cell Biol. 13:2001;662-665.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 662-665
    • Goodell, M.A.1
  • 24
    • 0035112448 scopus 로고    scopus 로고
    • Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes
    • Grapin-Botton A., Majithia A.R., Melton D.A. Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes. Genes Dev. 15:2001;444-454.
    • (2001) Genes Dev. , vol.15 , pp. 444-454
    • Grapin-Botton, A.1    Majithia, A.R.2    Melton, D.A.3
  • 26
    • 0035141324 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
    • Hayhurst G.P., Lee Y.H., Lambert G., Ward J.M., Gonzalez F.J. Hepatocyte nuclear factor 4 alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol. Cell. Biol. 21:2001;1393-1403.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1393-1403
    • Hayhurst, G.P.1    Lee, Y.H.2    Lambert, G.3    Ward, J.M.4    Gonzalez, F.J.5
  • 27
    • 0031904172 scopus 로고    scopus 로고
    • Misexpression of the pancreatic homeodomain protein IDX-1 by the Hoxa-4 promoter associated with agenesis of the cecum
    • Heller R.S., Stoffers D.A., Hussain M.A., Miller C.P., Habener J.F. Misexpression of the pancreatic homeodomain protein IDX-1 by the Hoxa-4 promoter associated with agenesis of the cecum. Gastroenterology. 115:1998;381-387.
    • (1998) Gastroenterology , vol.115 , pp. 381-387
    • Heller, R.S.1    Stoffers, D.A.2    Hussain, M.A.3    Miller, C.P.4    Habener, J.F.5
  • 28
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J., Carlsson L., Edlund T., Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature. 371:1994;606-609.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 29
    • 0033580985 scopus 로고    scopus 로고
    • Initiation of mammalian liver development from endoderm by fibroblast growth factors
    • Jung J., Zheng M., Goldfarb M., Zaret K.S. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science. 284:1999;1998-2003.
    • (1999) Science , vol.284 , pp. 1998-2003
    • Jung, J.1    Zheng, M.2    Goldfarb, M.3    Zaret, K.S.4
  • 32
    • 0033065925 scopus 로고    scopus 로고
    • Pancreatic expression of keratinocyte growth factor leads to differentiation of islet hepatocytes and proliferation of duct cells
    • Krakowski M.L., Kritzik M.R., Jones E.M., Krahl T., Lee J., Arnush M., Gu D., Sarvetnick N. Pancreatic expression of keratinocyte growth factor leads to differentiation of islet hepatocytes and proliferation of duct cells. Am. J. Pathol. 154:1999;683-691.
    • (1999) Am. J. Pathol. , vol.154 , pp. 683-691
    • Krakowski, M.L.1    Kritzik, M.R.2    Jones, E.M.3    Krahl, T.4    Lee, J.5    Arnush, M.6    Gu, D.7    Sarvetnick, N.8
  • 34
    • 0024560121 scopus 로고
    • Metaplastic pancreatic cells in liver tumors induced by diethylnitrosamine
    • Lee B.C., Hendricks J.D., Bailey G.S. Metaplastic pancreatic cells in liver tumors induced by diethylnitrosamine. Exp. Mol. Pathol. 50:1989;104-113.
    • (1989) Exp. Mol. Pathol. , vol.50 , pp. 104-113
    • Lee, B.C.1    Hendricks, J.D.2    Bailey, G.S.3
  • 35
    • 0034090310 scopus 로고    scopus 로고
    • Mammalian hepatocyte differentiation requires the transcription factor HNF4α
    • Li J., Ning G., Duncan S.A. Mammalian hepatocyte differentiation requires the transcription factor HNF4α Genes Dev. 14:2000;464-474.
    • (2000) Genes Dev. , vol.14 , pp. 464-474
    • Li, J.1    Ning, G.2    Duncan, S.A.3
  • 38
    • 0021961927 scopus 로고
    • Glucocorticoids increase amylase mRNA levels, secretory organelles, and secretion in pancreatic acinar AR42J cells
    • Logsdon C.D., Moessner J., William J.A., Goldfine I.D. Glucocorticoids increase amylase mRNA levels, secretory organelles, and secretion in pancreatic acinar AR42J cells. J. Cell Biol. 100:1985;1200-1208.
    • (1985) J. Cell Biol. , vol.100 , pp. 1200-1208
    • Logsdon, C.D.1    Moessner, J.2    William, J.A.3    Goldfine, I.D.4
  • 40
    • 0029815929 scopus 로고    scopus 로고
    • Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor
    • Mashima H., Shibata H., Mine T., Kojima I. Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor. Endocrinology. 137:1996;3969-3976.
    • (1996) Endocrinology , vol.137 , pp. 3969-3976
    • Mashima, H.1    Shibata, H.2    Mine, T.3    Kojima, I.4
  • 41
    • 0018873607 scopus 로고
    • Distribution of maker enzymes and mucin in intestinal metaplasia in human stomach and relation of complete and incomplete metaplasia to minute gastric carcinomas
    • Matsukura N., Suzuki K., Kaeachi T., Aoyagi M., Sugimura T., Kitaoka H., Numajiri H., Shirota A., Habashi M., Hirota T. Distribution of maker enzymes and mucin in intestinal metaplasia in human stomach and relation of complete and incomplete metaplasia to minute gastric carcinomas. J. Natl. Cancer Inst. 65:1980;231-240.
    • (1980) J. Natl. Cancer Inst. , vol.65 , pp. 231-240
    • Matsukura, N.1    Suzuki, K.2    Kaeachi, T.3    Aoyagi, M.4    Sugimura, T.5    Kitaoka, H.6    Numajiri, H.7    Shirota, A.8    Habashi, M.9    Hirota, T.10
  • 42
    • 0028246642 scopus 로고
    • Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas
    • Miquerol L., Lopez S., Cartier N., Tulliez M., Raymondjean M., Kahn A. Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas. J. Biol. Chem. 269:1994;8944-8951.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8944-8951
    • Miquerol, L.1    Lopez, S.2    Cartier, N.3    Tulliez, M.4    Raymondjean, M.5    Kahn, A.6
  • 43
    • 0025891949 scopus 로고
    • Multicentric focal acinar cell hyperplasia and hepatocyte-like cell metaplasia are induced by nitrosomethylurea in rat pancreas
    • Monis B., Valentich M.A., Urrutia R., Rivolta M. Multicentric focal acinar cell hyperplasia and hepatocyte-like cell metaplasia are induced by nitrosomethylurea in rat pancreas. Int. J. Pancreatol. 8:1991;119-131.
    • (1991) Int. J. Pancreatol. , vol.8 , pp. 119-131
    • Monis, B.1    Valentich, M.A.2    Urrutia, R.3    Rivolta, M.4
  • 44
    • 0028291370 scopus 로고
    • Expression of hepatic transcription factors during liver development and oval cell differentiation
    • Nagy P., Bisgaard H.C., Thorgeirsson S.S. Expression of hepatic transcription factors during liver development and oval cell differentiation. J. Cell Biol. 126:1994;223-233.
    • (1994) J. Cell Biol. , vol.126 , pp. 223-233
    • Nagy, P.1    Bisgaard, H.C.2    Thorgeirsson, S.S.3
  • 47
    • 0034177614 scopus 로고    scopus 로고
    • Hepatoid carcinoma of the pancreas
    • Paner G.P., Thompson K.S., Reyes C.V. Hepatoid carcinoma of the pancreas. Cancer. 88:2000;1582-1589.
    • (2000) Cancer , vol.88 , pp. 1582-1589
    • Paner, G.P.1    Thompson, K.S.2    Reyes, C.V.3
  • 48
    • 0029585231 scopus 로고
    • Evidence for developmentally programmed transdifferentiation in mouse esophageal muscle
    • Patapoutian A., Wold B.J., Wagner R.A. Evidence for developmentally programmed transdifferentiation in mouse esophageal muscle. Science. 270:1995;1818-1821.
    • (1995) Science , vol.270 , pp. 1818-1821
    • Patapoutian, A.1    Wold, B.J.2    Wagner, R.A.3
  • 50
    • 0034100823 scopus 로고    scopus 로고
    • Reversal of insulin-dependent diabetes using islets generated in virto from pancreatic stem cells
    • Ramiya V.K., Maraist M., Arfors K.E., Schatz D.A., Peck A.B., Cornelius J.G. Reversal of insulin-dependent diabetes using islets generated in virto from pancreatic stem cells. Nat. Med. 6:2000;278-282.
    • (2000) Nat. Med. , vol.6 , pp. 278-282
    • Ramiya, V.K.1    Maraist, M.2    Arfors, K.E.3    Schatz, D.A.4    Peck, A.B.5    Cornelius, J.G.6
  • 51
    • 0020400688 scopus 로고
    • Response of chemically induced hepatocytelike cells in hamster pancreas to methyl clofenapate, a peroxisome proliferator
    • Rao M.S., Reddy M.K., Reddy J.K., Scarpelli D.G. Response of chemically induced hepatocytelike cells in hamster pancreas to methyl clofenapate, a peroxisome proliferator. J. Cell Biol. 95:1982;50-56.
    • (1982) J. Cell Biol. , vol.95 , pp. 50-56
    • Rao, M.S.1    Reddy, M.K.2    Reddy, J.K.3    Scarpelli, D.G.4
  • 52
    • 0022624097 scopus 로고
    • Characterization of pancreatic-type tissue in the liver of rat induced by polychlorinated biphenyls
    • Rao M.S., Bendayan M., Kimbrough R.D., Reddy J.K. Characterization of pancreatic-type tissue in the liver of rat induced by polychlorinated biphenyls. J. Histochem. Cytochem. 34:1986;197-201.
    • (1986) J. Histochem. Cytochem. , vol.34 , pp. 197-201
    • Rao, M.S.1    Bendayan, M.2    Kimbrough, R.D.3    Reddy, J.K.4
  • 53
    • 0022617147 scopus 로고
    • Induction of hepatocytes in the pancreas of copper-depleted rats following copper repletion
    • Rao M.S., Subbarao V., Reddy J.K. Induction of hepatocytes in the pancreas of copper-depleted rats following copper repletion. Cell Differ. 18:1986;109-117.
    • (1986) Cell Differ. , vol.18 , pp. 109-117
    • Rao, M.S.1    Subbarao, V.2    Reddy, J.K.3
  • 55
    • 0023692370 scopus 로고
    • Development of hepatocytes in the pancreas of hamsters treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Rao M.S., Subbarao V., Scarpelli D.G. Development of hepatocytes in the pancreas of hamsters treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Toxicol. Environ. Health. 25:1988;201-205.
    • (1988) J. Toxicol. Environ. Health , vol.25 , pp. 201-205
    • Rao, M.S.1    Subbarao, V.2    Scarpelli, D.G.3
  • 57
    • 0030338534 scopus 로고    scopus 로고
    • Expression of transcription factors and stem cell factor precedes hepatocyte differentiation in rat pancreas
    • Rao M.S., Yukawa M., Omori M., Thorgeirsson S.S., Reddy J.K. Expression of transcription factors and stem cell factor precedes hepatocyte differentiation in rat pancreas. Gene. Expr. 6:1996;15-22.
    • (1996) Gene. Expr. , vol.6 , pp. 15-22
    • Rao, M.S.1    Yukawa, M.2    Omori, M.3    Thorgeirsson, S.S.4    Reddy, J.K.5
  • 59
    • 0027050866 scopus 로고
    • Drosophila C/EBP: A tissue-specific DNA-binding protein required for embryonic development
    • Rørth P., Montell D.J. Drosophila C/EBP: a tissue-specific DNA-binding protein required for embryonic development. Gene Dev. 6:1992;2299-2311.
    • (1992) Gene Dev. , vol.6 , pp. 2299-2311
    • Rørth, P.1    Montell, D.J.2
  • 60
    • 0035423751 scopus 로고    scopus 로고
    • Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm
    • Rossi J.M., Dunn N.R., Hogan B.L., Zaret K.S. Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev. 15:2001;1998-2009.
    • (2001) Genes Dev. , vol.15 , pp. 1998-2009
    • Rossi, J.M.1    Dunn, N.R.2    Hogan, B.L.3    Zaret, K.S.4
  • 61
    • 0042703059 scopus 로고
    • Differentiation of regenerating pancreatic cells into hepatocyte-like cells
    • Scarpelli D.G., Rao M.S. Differentiation of regenerating pancreatic cells into hepatocyte-like cells. Proc. Natl. Acad. Sci. USA. 78:1981;2577-2581.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 2577-2581
    • Scarpelli, D.G.1    Rao, M.S.2
  • 62
    • 0029879758 scopus 로고    scopus 로고
    • Cloning and sequencing of 5′ region of the human glucose-6-phosphatase gene: Transcriptional regulation by camp, insulin and glucocorticoid in H4IIE hepatoma cells
    • Schmoll D., Allan B.B., Burchell A. Cloning and sequencing of 5′ region of the human glucose-6-phosphatase gene: transcriptional regulation by camp, insulin and glucocorticoid in H4IIE hepatoma cells. FEBS Lett. 383:1996;63-66.
    • (1996) FEBS Lett. , vol.383 , pp. 63-66
    • Schmoll, D.1    Allan, B.B.2    Burchell, A.3
  • 64
    • 0016192336 scopus 로고
    • Transdifferentiation in the labial gland of silk moths: Is DNA required for cellular metamorphosis?
    • Selman K., Kafatos F.C. Transdifferentiation in the labial gland of silk moths: is DNA required for cellular metamorphosis? Cell Differ. 3:1974;81-94.
    • (1974) Cell Differ. , vol.3 , pp. 81-94
    • Selman, K.1    Kafatos, F.C.2
  • 65
    • 0033672199 scopus 로고    scopus 로고
    • Molecular basis of transdifferentiation of pancreas to liver
    • Shen C.N., Slack J.M.W., Tosh D. Molecular basis of transdifferentiation of pancreas to liver. Nat. Cell Biol. 2:2000;879-887.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 879-887
    • Shen, C.N.1    Slack, J.M.W.2    Tosh, D.3
  • 66
    • 0022359072 scopus 로고
    • Homoeotic transformations in man: Implications for the mechanism of embryonic development and for the organization of epithelia
    • Slack J.M.W. Homoeotic transformations in man: implications for the mechanism of embryonic development and for the organization of epithelia. J. Theor. Biol. 114:1985;463-490.
    • (1985) J. Theor. Biol. , vol.114 , pp. 463-490
    • Slack, J.M.W.1
  • 67
    • 0022601893 scopus 로고
    • Epithelial metaplasia and the second anatomy
    • Slack J.M.W. Epithelial metaplasia and the second anatomy. Lancet. 2:1986;268-271.
    • (1986) Lancet , vol.2 , pp. 268-271
    • Slack, J.M.W.1
  • 68
    • 0034712075 scopus 로고    scopus 로고
    • Stem cells in epithelial tissues
    • Slack J.M.W. Stem cells in epithelial tissues. Science. 287:2000;1431-1433.
    • (2000) Science , vol.287 , pp. 1431-1433
    • Slack, J.M.W.1
  • 69
    • 0035479834 scopus 로고    scopus 로고
    • Transdifferentiation and metaplasia-switching cell types
    • Slack J.M.W., Tosh D. Transdifferentiation and metaplasia-switching cell types. Curr. Opin. Genet Dev. 11:2001;581-586.
    • (2001) Curr. Opin. Genet Dev. , vol.11 , pp. 581-586
    • Slack, J.M.W.1    Tosh, D.2
  • 70
    • 0025690311 scopus 로고
    • Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
    • Sladek F.M., Zhong W.M., Lai E., Darnell J.J. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev. 4:1990;2353-2365.
    • (1990) Genes Dev. , vol.4 , pp. 2353-2365
    • Sladek, F.M.1    Zhong, W.M.2    Lai, E.3    Darnell, J.J.4
  • 71
    • 0345245156 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells
    • Spath G.F., Weiss M.C. Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells. Mol. Cell. Biol. 17:1997;1913-1922.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1913-1922
    • Spath, G.F.1    Weiss, M.C.2
  • 72
    • 0032559647 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells
    • Spath G.F., Weiss M.C. Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells. J. Cell Biol. 140:1998;935-946.
    • (1998) J. Cell Biol. , vol.140 , pp. 935-946
    • Spath, G.F.1    Weiss, M.C.2
  • 73
    • 0024670402 scopus 로고
    • Differential requirements for cell-specific elastase I enhancer domains in transfected cells and transgenic mice
    • Swift G.H., Kruse F., MacDonald R.J., Hammer R.E. Differential requirements for cell-specific elastase I enhancer domains in transfected cells and transgenic mice. Genes Dev. 3:1989;687-696.
    • (1989) Genes Dev. , vol.3 , pp. 687-696
    • Swift, G.H.1    Kruse, F.2    MacDonald, R.J.3    Hammer, R.E.4
  • 74
    • 0031435337 scopus 로고    scopus 로고
    • Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene
    • Tanaka T., Yoshida N., Kishimoto T., Akira S. Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. EMBO J. 16:1997;7432-7443.
    • (1997) EMBO J. , vol.16 , pp. 7432-7443
    • Tanaka, T.1    Yoshida, N.2    Kishimoto, T.3    Akira, S.4
  • 75
    • 0028933919 scopus 로고
    • Expression of pancreatic enzymes (alpha-amylase, trypsinogen, and lipase) during human liver development and maturation
    • Terada T., Nakanuma Y. Expression of pancreatic enzymes (alpha-amylase, trypsinogen, and lipase) during human liver development and maturation. Gastroenterology. 108:1995;1236-1245.
    • (1995) Gastroenterology , vol.108 , pp. 1236-1245
    • Terada, T.1    Nakanuma, Y.2
  • 78
    • 0026928723 scopus 로고
    • HNF1, a homeoprotein member of the hepatic transcription regulatory network
    • Tronche F., Yaniv M. HNF1, a homeoprotein member of the hepatic transcription regulatory network. Bioessays. 14:1992;579-587.
    • (1992) Bioessays , vol.14 , pp. 579-587
    • Tronche, F.1    Yaniv, M.2
  • 79
    • 0027477125 scopus 로고
    • Immunohistochemical evidence of high concentrations of metallothionein in pancreatic hepatocytes induced by cadmium in rats
    • Waalkes M.P., Cherian M.G., Ward J.M., Goyer R.A. Immunohistochemical evidence of high concentrations of metallothionein in pancreatic hepatocytes induced by cadmium in rats. Toxicol. Pathol. 20:1992;323-326.
    • (1992) Toxicol. Pathol. , vol.20 , pp. 323-326
    • Waalkes, M.P.1    Cherian, M.G.2    Ward, J.M.3    Goyer, R.A.4
  • 81
    • 0032538883 scopus 로고    scopus 로고
    • Dominant-negative suppression of HNF-1α function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic β-cell line
    • Wang H., Maechler P., Hagenfeldt K.A., Wollheim C.B. Dominant-negative suppression of HNF-1α function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic β-cell line. EMBO J. 17:1998;6701-6713.
    • (1998) EMBO J. , vol.17 , pp. 6701-6713
    • Wang, H.1    Maechler, P.2    Hagenfeldt, K.A.3    Wollheim, C.B.4
  • 82
    • 0035132173 scopus 로고    scopus 로고
    • Liver repopulation and correction of metabolic liver disease by transplanted adult mouse pancreatic cells
    • Wang X., Al-Dhalimy M., Lagasse E., Finegold M., Grompe M. Liver repopulation and correction of metabolic liver disease by transplanted adult mouse pancreatic cells. Am. J. Pathol. 158:2001;571-579.
    • (2001) Am. J. Pathol. , vol.158 , pp. 571-579
    • Wang, X.1    Al-Dhalimy, M.2    Lagasse, E.3    Finegold, M.4    Grompe, M.5
  • 83
    • 0014993124 scopus 로고
    • Glandular neoplasia within the urinary tract. The aetiology of adenocarcinoma of the urothelium with a review of the literature
    • Ward A.M. Glandular neoplasia within the urinary tract. The aetiology of adenocarcinoma of the urothelium with a review of the literature. Virchows. Arch. Pathol. Anat. 352:1971;296-311.
    • (1971) Virchows. Arch. Pathol. Anat. , vol.352 , pp. 296-311
    • Ward, A.M.1
  • 86
    • 0029927506 scopus 로고    scopus 로고
    • The non-human primate endocrine pancreas: Development, regeneration potential and metaplasia
    • Wolfe-Coote S., Louw J., Woodroof C., Du Toit D.F. The non-human primate endocrine pancreas: development, regeneration potential and metaplasia. Cell Biol. Int. 20:1996;95-101.
    • (1996) Cell Biol. Int. , vol.20 , pp. 95-101
    • Wolfe-Coote, S.1    Louw, J.2    Woodroof, C.3    Du Toit, D.F.4
  • 88
  • 89
    • 0035479967 scopus 로고    scopus 로고
    • Hepatocyte differentiation: From the endoderm and beyond
    • Zaret K.S. Hepatocyte differentiation: from the endoderm and beyond. Curr. Opin. Genet. Dev. 11:2001;568-574.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 568-574
    • Zaret, K.S.1
  • 90
    • 0033512486 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells
    • Zhou J., Wang X., Pineyro M.A., Egan J.M. Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells. Diabetes. 48:1999;2358-2366.
    • (1999) Diabetes , vol.48 , pp. 2358-2366
    • Zhou, J.1    Wang, X.2    Pineyro, M.A.3    Egan, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.