Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: Tetraploid rescue of Hnf-4(-/-) embryos

Development

Volumn 124, Issue 2, 1997, Pages 279-287

  Duncan, Stephen A ^a   Nagy, Andras ^b   Chan, Wendy ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

ES cells; Gastrulation; HNF 4; Mouse; Tetraploid; Transcription; Visceral endoderm

Indexed keywords

ALPHA FETOPROTEIN; APOLIPOPROTEIN; PREALBUMIN; RETINOL BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSFERRIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; ECTODERM; EMBRYO; ENDODERM; GASTRULATION; GENE EXPRESSION; GERM LAYER; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; TETRAPLOIDY;

ANIMALS; DNA-BINDING PROTEINS; EMBRYONIC AND FETAL DEVELOPMENT; ENDODERM; GASTRULA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; HEPATOCYTE NUCLEAR FACTOR 4; IN SITU HYBRIDIZATION; MICE; MICE, KNOCKOUT; PHOSPHOPROTEINS; POLYMERASE CHAIN REACTION; POLYPLOIDY; RNA, MESSENGER; STEM CELLS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VISCERA;

ANIMALIA; MURINAE;

EID: 0031054568     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Ang, S. L. and Rossant, J. (1994). HNF-3β is essential for node and notochord formation in mouse development. Cell 78, 561-574.
2. Barton, S. C., Surani, M. A. H. and Norris, M. L. (1984). Role of paternal and maternal genomes in mouse development. Nature 311, 374-376.
3. Basheeruddin, K., Stein, P., Strickland, S. and Williams, D. L. (1987) Expression of the murine apolipoprotein E gene is coupled to the differentiated state of F9 embryonal carcinoma cells. Proc. Natl. Acad. Sci. USA 84, 709-713.
4. Brent, R. L., Beckman, D. A., Jensen, M. and Koszalka, T. R. (1990). Experimental yolk sac dysfunction as a model for studying nutritional disturbances in the embryo during organogenesis. Teratology 41, 405-413.
5. Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Erberhardt, C., Declercq, C., Pawling, J., Moons, L., Collen, D., Risau, W. and Nagy, A. (1996). Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380, 435-439.
6. Cereghini, S., Ott, M.-O., Power, S. and Maury, M. (1992). Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles. Development 116, 783-797.
7. Chen, W. S., Manova, K., Weinstein, D. C., Duncan, S. A., Plump, A. S., Prezioso, V. R., Bachvarova, R. F. and Darnell, J. E., Jr. (1994). Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev. 8, 2466-2477.
8. Coucouvanis, E. and Martin, G. R. (1995). Signals for death and survival: a two-step mechanism for cavitation in the vertebrate embryo. Cell 83, 279-287.
9. Doetschman, T. C., Eistetter, H., Katz, M., Schmidt, W. and Kemler, R. (1985). The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J. Embryol. Exp. Morphol. 87, 27-45.
10. Drewes, T., Senkel, S., Holewa, B. and Ryffel, G. U. (1996). Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes. Mol. Cell Biol. 16, 925-931.
11. Duncan, S. A., Manova, K., Chen, W. S., Hoodless, P., Weinstein, D. C., Bachvarova, R. F. and Darnell, J. E., Jr. (1994). Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc. Natl. Acad. Sci. USA 91, 7598-7602.
12. Episkopou, V., Maeda, S., Nishiguchi, S., Kazunori, S., Gaitanaris, G. A., Gottesman, M. E. and Robertson, E. J. (1993). Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone. Proc. Nat. Acad. Sci. USA 90, 2375-2379.
13. Evans, M. J. and Kaufman, M. H. (1981). Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156.
14. Farese, R. V., Ruland, S. L., Flynn, L. M., Stokowski, R. P. and Young, S. G. (1995). Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. Proc. Natl. Acad. Sci. USA 92, 1774-1778.
15. Gardner, R. L. (1983). Origin and differentiation of extraembryonic endoderm in the mouse. J. Embryol. Exp. Morphol. 80, 251-288.
16. Grover, A., Andrews, G. and Adamson, E. D. (1983a). Role of laminin in epithelium formation by F9 aggregates. J. Cell Biol. 97, 137-144.
17. Grover, A., Oshima, R. G. and Adamson, E. D. (1983b). Epithelial layer formation in differentiating aggregates of F9 embryonal carcinoma cells. J. Cell Biol. 96, 1690-1696.
18. Guillemot, F., Nagy, A., Auerbach, A. and Joyner, A. L. (1994). Essential role of Mash-2 in extraembryonic development. Nature 371, 333-336.
19. Harrison, S. M., Dunwoodie, S. L., Arkell, R. M., Lerach, H. and Beddington, R. S. P. (1995). Isolation of novel tissue-specific genes from cDNA libraries representing the individual constituents of the gastrulating mouse embryo. Development 121, 2479-2489.
20. Heath, J. K. and Deller, M. J. (1983). Serum-free culture of PC13 murine embryonal carcinoma cells. J. Cell. Physiol. 115, 225-230.
21. Hooper, M., Hardy, K., Handyside, A., Hunter, S. and Monk, M. (1987) HPRT-deficient (Lesch-Nyan) mouse embryos derived from germline colonization by cultured cells. Nature 326, 292-295.
22. Huang, L. S., Voyiaziakis, E., Markenson, D. F., Sokol, K. A., Hayek, T. and Breslow, J. L. (1995). Apo B gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and Apo A-I transport rates in heterozygotes. J. Clin. Invest. 96, 2152-2161.
23. Jollie, W. P. (1990). Development, morphology, and function of the yolk-sacplacenta of laboratory rodents. Terat. 41, 361-381.
24. Kaufman, M. H., Barton, S. C. and Surani, A. A. H. (1977). Normal postimplantation development of mouse parthenogenetic embryos to the forelimb bud stage. Nature 265, 53-55.
25. Kubiak, J. C. and Tarkowski, A. K. (1985). Electrofusion of mouse blastomeres. Exp. Cell. Res. 157, 561-566.
26. Kuo, C. J., Conley, P. B., Chen, L., Sladek, F. M., Darnell, J. E., Jr. and Crabtree, G. R. (1992). A transcriptional hierarchy involved in mammalian cell-type specification. Nature 355, 458-460.
27. Lee, J. J., Radice, G., Perkins, C. P. and Constantini, F. (1992). Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine Hß58 embryonic lethal transgene insertion. Development 115, 277-288.
28. Martin, G. R. (1981). Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA 78, 7634-7638.
29. McGrath, J. and Solter, D. (1984). Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell 37, 179-183.
30. McLaughlin, K. L. (1993). Production of tetraploid embryos by electrofusion. In Guide to techniques in mouse development, (P. M. Wasserman and DePamphilis, M. L.), pp. 919-929. Academic Press, Inc., San Diego.
31. Meehan, R. R., Barlow, D. P., Hill, R. E., Hogan, B. L. M. and Hastie, N. D. (1984). Pattern of serum protein gene expression in the mouse visceral yolk sac and foetal liver. EMBO J. 3, 1881-1885.
32. Mortensen, R. M., Conner, D. A., Chao, S., Geisterfer-Lowrance, A. A. T. and Seidman, J. G. (1992). Production of homozygous mutant ES cells with a single targeting construct. Mol. Cell. Biol. 12, 2391-2395.
33. Nagy, A., Gocza, E., Diaz, E. M., Prideaux, V. R., Ivanyi, E., Markkula, M. and Rossant, J. (1990). Embryonic stem cells alone are able to support fetal development in the mouse. Development 110, 815-821.
34. Nagy, A. and Rossant, J. (1993). Production of completely ES cell-derived fetuses. In Gene Targeting: A Practical Approach, (A. Joyner), pp. 147-179. Oxford Unviersity Press, Oxford, UK.
35. Plump, A. S., Smith, j. D., Hayek, T., Aalto-Setaa, K., Walsh, A., Verstuyft, J. G., Rubin, E. M. and Breslow, J. L. (1992). Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 71, 343-353.
36. Pontoglio, M., Barra, J., Hadchouei, M., Doyen, A., Kress, C., Bach, J. P., Babinet, C. and Yaniv, M. (1996). Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria and renal Fanconi syndrome. Cell 84, 575-585.
37. Robertson, E. J. (1987). Embryo-derived stem cell lines. In Teratocarcinomas and Embryonic Stem Cells: A Practical Approach, (E. J. Robertson), pp. 71-112. IRL press, Oxford, UK.
38. Sato, M. and Muramatsu, T. (1985). Reactivity of five N-acetylgalactosamine-recognizing lectins with preimplantation embryos, early postimplantation embryos, and teratocarcinoma cells of the mouse. Diff. 29, 29-38.
39. Sladek, F. M. (1994). Hepatocyte nuclear factor 4 (HNF-4). In Transcriptional Regulation of Liver Specific Genes (ed. F. Tronch and Yanish, M.), pp. R.G. Landes Company, Austin, TX, USA.
40. Sladek, F. M., Zhong, W., Lai, E. and Darnell, J. E., Jr. (1990). Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev. 4, 2353-2365.
41. Soudais, C., Bielinska, M., Heikinheimo, M., MacArthur, C. A., Narita, N., Saffitz, J. E., Simon, M. C., Leiden, J. M. and Wilson, D. B. (1995). Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro. Development 121, 3877-3888.
42. Spyropoulos, D. D. and Capecchi, M. R. (1994). Targeted disruption of the even-skipped gene, evxl, causes early postimplantation lethality of the mouse conceptus. Genes Dev. 8, 1949-1961.
43. Sturm, K., Flannery, M. L. and Pederson, R. A. (1994). Abnormal development of embryonic and extraembryonic cell lineages in parthenogenetic mouse embryos. Dev. Dyn. 201, 11-28.
44. Surani, M. A. H., Barton, S. C. and Norris, M. L. (1984). Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature 308, 548-308.
45. Taraviras, S., Monaghan, A. P., Schutz, G. and Kelsey, G. (1994) Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis. Mech. Dev. 48, 67-79.
46. Tian, J. M. and Schibler, U. (1991). Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4. Genes Dev. 5, 2225-2234.
47. Weinstein, D. C., Altaba, A. R. i., Chen, W. S., Hoodless, P., Prezioso, V. R., Jessell, T. M. and Darnell, J. E., Jr. (1994). The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo. Cell 78, 575-588.
48. Williamson, R., Lee, D., Hagaman, J. and Maeda, N. (1992). Marked reduction in high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I. Proc. Natl. Acad. Sci. USA 89, 7134-7138.
49. Wilson, P. A. and Melton, D. A. (1994). Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication. Curr. Biol. 4, 676-686.
50. Wu, T.-C., Wan, Y.-J. and Damjanov, I. (1983). Flourescein-conjugated Badeira simplicifolia lectin as a marker of endodermal, yolk sac and trophoblastic differentiaition in the mouse embryo. Diff. 24, 55-59.
51. Zhong, W., Sladek, F. M. and Darnell, J. E., Jr. (1993). The expression pattern of a Drosophila homolog to the mouse transcription factor HNF-4 suggests a determinative role in gut formation. EMBO J. 12, 537-544.