-
1
-
-
0023555012
-
1,2-Diacylglycerols, but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells
-
Kolesnick R.N., Paley A.E. 1,2-Diacylglycerols, but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells. J. Biol. Chem. 262:1987;9204-9210.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 9204-9210
-
-
Kolesnick, R.N.1
Paley, A.E.2
-
2
-
-
0024795059
-
Sphingomyelin turnover induced by vitamin D3 in HL-60 cells
-
Okazaki T., Bell R.M., Hannun Y.A. Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. J. Biol. Chem. 264:1989;19076-19080.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 19076-19080
-
-
Okazaki, T.1
Bell, R.M.2
Hannun, Y.A.3
-
3
-
-
0028095477
-
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase
-
Cifone M.G., De Maria R., Roncaioli P., Rippo M.R., Azuma M., Lanier L.L., Santoni A., Testi R. Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J. Exp. Med. 180:1994;1547-1552.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1547-1552
-
-
Cifone, M.G.1
De Maria, R.2
Roncaioli, P.3
Rippo, M.R.4
Azuma, M.5
Lanier, L.L.6
Santoni, A.7
Testi, R.8
-
4
-
-
0028964917
-
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway
-
Gulbins E., Bissonnette R., Mahboubi A., Martin S., Nishioka W., Brunner T., Baier G., Baier-Bitterlich G., Byrd C., Lang F., Kolesnick R., Altman A., Green D. FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity. 2:1995;341-351.
-
(1995)
Immunity
, vol.2
, pp. 341-351
-
-
Gulbins, E.1
Bissonnette, R.2
Mahboubi, A.3
Martin, S.4
Nishioka, W.5
Brunner, T.6
Baier, G.7
Baier-Bitterlich, G.8
Byrd, C.9
Lang, F.10
Kolesnick, R.11
Altman, A.12
Green, D.13
-
5
-
-
0028790239
-
Multiple pathways originate at the Fas/APO-1 (CD95) receptor: Sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal
-
Cifone M.G., Roncaioli P., De Maria R., Camarda G., Santoni A., Ruberti G., Testi R. Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal. EMBO J. 14:1995;5859-5868.
-
(1995)
EMBO J.
, vol.14
, pp. 5859-5868
-
-
Cifone, M.G.1
Roncaioli, P.2
De Maria, R.3
Camarda, G.4
Santoni, A.5
Ruberti, G.6
Testi, R.7
-
6
-
-
0026458406
-
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
-
Schütze S., Potthoff K., Machleidt T., Berkovic D., Wiegmann K., Krönke M. TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell. 71:1992;765-776.
-
(1992)
Cell
, vol.71
, pp. 765-776
-
-
Schütze, S.1
Potthoff, K.2
Machleidt, T.3
Berkovic, D.4
Wiegmann, K.5
Krönke, M.6
-
7
-
-
0027461121
-
Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta
-
Mathias S., Younes A., Kan C.C., Orlow I., Joseph C., Kolesnick R.N. Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta. Science. 259:1993;519-522.
-
(1993)
Science
, vol.259
, pp. 519-522
-
-
Mathias, S.1
Younes, A.2
Kan, C.C.3
Orlow, I.4
Joseph, C.5
Kolesnick, R.N.6
-
8
-
-
16044364385
-
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
-
Santana P., Pena L.A., Haimovitz-Friedman A., Martin S., Green D., McLoughlin M., Cordon-Cardo C., Schuchman E.H., Fuks Z., Kolesnick R. Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell. 86:1996;189-199.
-
(1996)
Cell
, vol.86
, pp. 189-199
-
-
Santana, P.1
Pena, L.A.2
Haimovitz-Friedman, A.3
Martin, S.4
Green, D.5
McLoughlin, M.6
Cordon-Cardo, C.7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
9
-
-
0035853751
-
Involvement of the acid sphingomyelinase pathway in UVA-induced apoptosis
-
Zhang Y., Mattjus P., Schmid P.C., Dong Z., Zhong S., Ma W.Y., Brown R.E., Bode A.M., Schmid H.H., Dong Z. Involvement of the acid sphingomyelinase pathway in UVA-induced apoptosis. J. Biol. Chem. 276:2001;11775-11782.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11775-11782
-
-
Zhang, Y.1
Mattjus, P.2
Schmid, P.C.3
Dong, Z.4
Zhong, S.5
Ma, W.Y.6
Brown, R.E.7
Bode, A.M.8
Schmid, H.H.9
Dong, Z.10
-
10
-
-
0034488193
-
Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis
-
Yu Z.F., Nikolova-Karakashian M., Zhou D., Cheng G., Schuchman E.H., Mattson P. Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis. J. Mol. Neurosci. 15:2000;85-97.
-
(2000)
J. Mol. Neurosci.
, vol.15
, pp. 85-97
-
-
Yu, Z.F.1
Nikolova-Karakashian, M.2
Zhou, D.3
Cheng, G.4
Schuchman, E.H.5
Mattson, P.6
-
11
-
-
0035175328
-
Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells
-
Esen M., Schreiner B., Jendrossek V., Lang F., Fassbender K., Grassmé H., Gulbins E. Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells. Apoptosis. 6:2001;441-445.
-
(2001)
Apoptosis
, vol.6
, pp. 441-445
-
-
Esen, M.1
Schreiner, B.2
Jendrossek, V.3
Lang, F.4
Fassbender, K.5
Grassmé, H.6
Gulbins, E.7
-
12
-
-
0033918950
-
Sindbis virus entry into cells triggers apoptosis by activating sphingomyelinase, leading to the release of ceramide
-
Jan J.T., Chatterjee S., Griffin D.E. Sindbis virus entry into cells triggers apoptosis by activating sphingomyelinase, leading to the release of ceramide. J. Virol. 74:2000;6425-6432.
-
(2000)
J. Virol.
, vol.74
, pp. 6425-6432
-
-
Jan, J.T.1
Chatterjee, S.2
Griffin, D.E.3
-
13
-
-
0036134864
-
Ceramide-rich membrane rafts mediate CD40 clustering
-
Grassmé H., Jendrossek V., Bock J., Riehle A., Gulbins E. Ceramide-rich membrane rafts mediate CD40 clustering. J. Immunol. 168:2002;298-307.
-
(2002)
J. Immunol.
, vol.168
, pp. 298-307
-
-
Grassmé, H.1
Jendrossek, V.2
Bock, J.3
Riehle, A.4
Gulbins, E.5
-
14
-
-
0033137104
-
Signaling through CD5 involves acidic sphingomyelinase, protein kinase c-zeta, mitogen activated protein kinase, and c-Jun NH2 terminal kinase
-
Simarro M., Calvo J., Vila J.M., Places L., Padilla O., Alberola-Ila J., Vives J., Lozano F. Signaling through CD5 involves acidic sphingomyelinase, protein kinase c-zeta, mitogen activated protein kinase, and c-Jun NH2 terminal kinase. J. Immunol. 162:1999;5149-5155.
-
(1999)
J. Immunol.
, vol.162
, pp. 5149-5155
-
-
Simarro, M.1
Calvo, J.2
Vila, J.M.3
Places, L.4
Padilla, O.5
Alberola-Ila, J.6
Vives, J.7
Lozano, F.8
-
15
-
-
0033136777
-
Signaling pathways activated by leukocyte function-associated Ag-1-dependent costimulation
-
Ni H.T., Deeths M.J., Mueller D.L., Mescher M.F. Signaling pathways activated by leukocyte function-associated Ag-1-dependent costimulation. J. Immunol. 162:1999;5183-5189.
-
(1999)
J. Immunol.
, vol.162
, pp. 5183-5189
-
-
Ni, H.T.1
Deeths, M.J.2
Mueller, D.L.3
Mescher, M.F.4
-
16
-
-
0029036715
-
CD28 signals through acidic sphingomyelinase
-
Boucher L.M., Wiegmann K., Futterer A., Pfeffer K., Machleidt T., Schütze S., Mak T.W., Krönke M. CD28 signals through acidic sphingomyelinase. J. Exp. Med. 181:1995;2059-2068.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 2059-2068
-
-
Boucher, L.M.1
Wiegmann, K.2
Futterer, A.3
Pfeffer, K.4
Machleidt, T.5
Schütze, S.6
Mak, T.W.7
Krönke, M.8
-
17
-
-
0030775369
-
Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells
-
Grassmé H., Gulbins E., Brenner B., Ferlinz K., Sandhoff K., Harzer K., Lang F., Meyer T.F. Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells. Cell. 91:1997;605-615.
-
(1997)
Cell
, vol.91
, pp. 605-615
-
-
Grassmé, H.1
Gulbins, E.2
Brenner, B.3
Ferlinz, K.4
Sandhoff, K.5
Harzer, K.6
Lang, F.7
Meyer, T.F.8
-
18
-
-
0032579258
-
Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development
-
Schissel S.L., Jiang X., Tweedie-Hardman J., Jeong T., Camejo E.H., Najib J., Rapp J.H., Williams K.J., Tabas I. Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development. J. Biol. Chem. 273:1998;2738-2746.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2738-2746
-
-
Schissel, S.L.1
Jiang, X.2
Tweedie-Hardman, J.3
Jeong, T.4
Camejo, E.H.5
Najib, J.6
Rapp, J.H.7
Williams, K.J.8
Tabas, I.9
-
19
-
-
0032540959
-
The cellular trafficking and zinc dependence of secretory and lysosomal sphingomyelinase, two products of the acid sphingomyelinase gene
-
Schissel S.L., Keesler G.A., Schuchman E.H., Williams K.J., Tabas I. The cellular trafficking and zinc dependence of secretory and lysosomal sphingomyelinase, two products of the acid sphingomyelinase gene. J. Biol. Chem. 273:1998;18250-18259.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18250-18259
-
-
Schissel, S.L.1
Keesler, G.A.2
Schuchman, E.H.3
Williams, K.J.4
Tabas, I.5
-
20
-
-
0035827632
-
CD95 signaling via ceramide-rich membrane rafts
-
Grassmé H., Jekle A., Riehle A., Schwarz H., Berger J., Sandhoff K., Kolesnick R., Gulbins E. CD95 signaling via ceramide-rich membrane rafts. J. Biol. Chem. 276:2001;20589-20596.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20589-20596
-
-
Grassmé, H.1
Jekle, A.2
Riehle, A.3
Schwarz, H.4
Berger, J.5
Sandhoff, K.6
Kolesnick, R.7
Gulbins, E.8
-
21
-
-
0021055866
-
The active site of lysosomal sphingomyelinase: Evidence for the involvement of hydrophobic and ionic groups
-
Callahan J.W., Jones C.S., Davidson D.J., Shankaran P. The active site of lysosomal sphingomyelinase: evidence for the involvement of hydrophobic and ionic groups. J. Neurosci. Res. 10:1983;151-163.
-
(1983)
J. Neurosci. Res.
, vol.10
, pp. 151-163
-
-
Callahan, J.W.1
Jones, C.S.2
Davidson, D.J.3
Shankaran, P.4
-
22
-
-
0029778534
-
Functional analysis of the glycosylation of murine acid sphingomyelinase
-
Newrzella D., Stoffel W. Functional analysis of the glycosylation of murine acid sphingomyelinase. J. Biol. Chem. 271:1996;32089-32095.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32089-32095
-
-
Newrzella, D.1
Stoffel, W.2
-
23
-
-
0035093880
-
Phosphoinositide 3-kinase crosstalk between Trk A tyrosine kinase and p75 (NTR)-dependent sphingolipid signaling pathways
-
Bilderback T.R., Gazula V.R., Dobrowsky R.T. Phosphoinositide 3-kinase crosstalk between Trk A tyrosine kinase and p75 (NTR)-dependent sphingolipid signaling pathways. Neurochemistry. 76:2001;1540-1551.
-
(2001)
Neurochemistry
, vol.76
, pp. 1540-1551
-
-
Bilderback, T.R.1
Gazula, V.R.2
Dobrowsky, R.T.3
-
24
-
-
0032489554
-
TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase
-
Schwandner R., Wiegmann K., Bernardo K., Kreder D., Krönke M. TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase. J. Biol. Chem. 273:1998;5916-5922.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5916-5922
-
-
Schwandner, R.1
Wiegmann, K.2
Bernardo, K.3
Kreder, D.4
Krönke, M.5
-
25
-
-
0027281373
-
A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen
-
Itoh N., Nagata S. A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. J. Biol. Chem. 268:1993;10932-10937.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10932-10937
-
-
Itoh, N.1
Nagata, S.2
-
26
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/Apo-1- and TNF receptor-induced cell death
-
Boldin M.P., Goncharov T.M., Goltsev Y.V., Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/Apo-1- and TNF receptor-induced cell death. Cell. 85:1996;803-815.
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
27
-
-
15844412409
-
FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing complex
-
Muzio M., Chinnaiyan A.M., Kischkel F.C., O'Rourke K., Shevchenko A., Ni J., Scaffidi C., Bretz J.D., Zhang M., Gentz R., Mann M., Krammer P.H., Peter M.E., Dixit V.M. FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing complex. Cell. 85:1996;817-827.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
Mann, M.11
Krammer, P.H.12
Peter, M.E.13
Dixit, V.M.14
-
28
-
-
0031873198
-
Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases
-
Brenner B., Ferlinz K., Grassmé H., Weller M., Koppenhoefer U., Dichgans J., Sandhoff K., Lang F., Gulbins E. Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases. Cell Death Differ. 5:1998;29-37.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 29-37
-
-
Brenner, B.1
Ferlinz, K.2
Grassmé, H.3
Weller, M.4
Koppenhoefer, U.5
Dichgans, J.6
Sandhoff, K.7
Lang, F.8
Gulbins, E.9
-
29
-
-
0034708455
-
CD95 (Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis
-
Grullich C., Sullards M.C., Fuks Z., Merrill A.H. Jr., Kolesnick R. CD95 (Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis. J. Biol. Chem. 275:2000;8650-8656.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8650-8656
-
-
Grullich, C.1
Sullards, M.C.2
Fuks, Z.3
Merrill A.H., Jr.4
Kolesnick, R.5
-
31
-
-
0030803278
-
Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153
-
Brenner B., Koppenhoefer U., Weinstock C., Linderkamp O., Lang F., Gulbins E. Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153. J. Biol. Chem. 272:1997;22173-22181.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22173-22181
-
-
Brenner, B.1
Koppenhoefer, U.2
Weinstock, C.3
Linderkamp, O.4
Lang, F.5
Gulbins, E.6
-
32
-
-
9544254849
-
Ras signaling in tumor necrosis factor-induced apoptosis
-
Trent J.C., McConkey D.J., Loughlin S.M., Harbison M.T., Fernandez A., Ananthaswamy H.M. Ras signaling in tumor necrosis factor-induced apoptosis. EMBO J. 15:1996;4497-4505.
-
(1996)
EMBO J.
, vol.15
, pp. 4497-4505
-
-
Trent, J.C.1
McConkey, D.J.2
Loughlin, S.M.3
Harbison, M.T.4
Fernandez, A.5
Ananthaswamy, H.M.6
-
33
-
-
0022976008
-
Role of cytoskeleton changes and expression of the H-ras oncogene during promotion of neoplastic transformation in mouse epidermal JB6 cells
-
Takahasi K., Heine U.I., Junker J.L., Colburn N.H., Rice J.M. Role of cytoskeleton changes and expression of the H-ras oncogene during promotion of neoplastic transformation in mouse epidermal JB6 cells. Cancer Res. 46:1986;5923-5932.
-
(1986)
Cancer Res.
, vol.46
, pp. 5923-5932
-
-
Takahasi, K.1
Heine, U.I.2
Junker, J.L.3
Colburn, N.H.4
Rice, J.M.5
-
34
-
-
0026654125
-
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
-
Ridley A.J., Peterson H.F., Johnston C.L., Diekmann D., Hall A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell. 70:1992;401-410.
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Peterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
35
-
-
0026512314
-
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface
-
Brown D.A., Rose J.K. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell. 68:1992;533-544.
-
(1992)
Cell
, vol.68
, pp. 533-544
-
-
Brown, D.A.1
Rose, J.K.2
-
36
-
-
0025695634
-
Cholesterol controls the clustering of the glycosphingolipid-anchored membrane receptor for 5-methyltetrahydrofolate
-
Rothberg K.G., Yang Y.S., Kamen B.A., Anderson R.G. Cholesterol controls the clustering of the glycosphingolipid-anchored membrane receptor for 5-methyltetrahydrofolate. J. Cell Biol. 111:1990;2931-2938.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 2931-2938
-
-
Rothberg, K.G.1
Yang, Y.S.2
Kamen, B.A.3
Anderson, R.G.4
-
37
-
-
0028151351
-
Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behaviour
-
Schroeder R., London E., Brown D. Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behaviour. Proc. Natl. Acad. Sci. U. S. A. 91:1994;12130-12134.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 12130-12134
-
-
Schroeder, R.1
London, E.2
Brown, D.3
-
38
-
-
0025118707
-
Organization of glycosphingolipids in phosphatidylcholine bilayers: Use of antibody molecules and Fab fragments as morphologic markers
-
Rock P., Allietta M., Young W.W., Thompson T.E., Tillack T.W. Organization of glycosphingolipids in phosphatidylcholine bilayers: use of antibody molecules and Fab fragments as morphologic markers. Biochemistry. 29:1990;8484-8490.
-
(1990)
Biochemistry
, vol.29
, pp. 8484-8490
-
-
Rock, P.1
Allietta, M.2
Young, W.W.3
Thompson, T.E.4
Tillack, T.W.5
-
39
-
-
0021749841
-
Direct visualization of redistribution and capping of fluorescent gangliosides on lymphocytes
-
Spiegel S., Kassis S., Wilchek M., Fishman P.H. Direct visualization of redistribution and capping of fluorescent gangliosides on lymphocytes. J. Cell Biol. 99:1984;1575-1581.
-
(1984)
J. Cell Biol.
, vol.99
, pp. 1575-1581
-
-
Spiegel, S.1
Kassis, S.2
Wilchek, M.3
Fishman, P.H.4
-
40
-
-
0029945751
-
Cholesterol-induced interfacial area condensations of galactosylceramides and sphingomyelins with identical acyl chains
-
Smaby J.M., Momsen M., Kulkarni V.S., Brown R.E. Cholesterol-induced interfacial area condensations of galactosylceramides and sphingomyelins with identical acyl chains. Biochemistry. 35:1996;5696-5704.
-
(1996)
Biochemistry
, vol.35
, pp. 5696-5704
-
-
Smaby, J.M.1
Momsen, M.2
Kulkarni, V.S.3
Brown, R.E.4
-
41
-
-
0025602953
-
Interaction of cholesterol with various glycerophospholipids and sphingomyelin
-
Sankaram M.B., Thompson T.E. Interaction of cholesterol with various glycerophospholipids and sphingomyelin. Biochemistry. 29:1990;10670-10675.
-
(1990)
Biochemistry
, vol.29
, pp. 10670-10675
-
-
Sankaram, M.B.1
Thompson, T.E.2
-
42
-
-
0030949124
-
Functional rafts in cell membranes
-
Simons K., Ikonen E. Functional rafts in cell membranes. Nature. 387:1997;569-572.
-
(1997)
Nature
, vol.387
, pp. 569-572
-
-
Simons, K.1
Ikonen, E.2
-
43
-
-
0032192469
-
Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands
-
Boniface J.J., Rabinowitz J.D., Wülfing C., Hampl J., Reich Z., Altan J.D., Kantor R.M., Beeson C., McConnell H.M., Davis M.M. Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands. Immunity. 9:1998;459-466.
-
(1998)
Immunity
, vol.9
, pp. 459-466
-
-
Boniface, J.J.1
Rabinowitz, J.D.2
Wülfing, C.3
Hampl, J.4
Reich, Z.5
Altan, J.D.6
Kantor, R.M.7
Beeson, C.8
McConnell, H.M.9
Davis, M.M.10
-
44
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks C.R., Freiberg B.A., Kupfer H., Sciaky N., Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature. 395:1998;82-86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
45
-
-
0025187903
-
Co-capping of ras proteins with surface immunoglobulins in B lymphocytes
-
Graziadei L., Riabowol K., Bar-Sagi D. Co-capping of ras proteins with surface immunoglobulins in B lymphocytes. Nature. 347:1990;396-399.
-
(1990)
Nature
, vol.347
, pp. 396-399
-
-
Graziadei, L.1
Riabowol, K.2
Bar-Sagi, D.3
-
46
-
-
0033431772
-
A role for lipid rafts in B cell antigen receptor signaling and antigen targeting
-
Cheng P.C., Dykstra M.L., Mitchell R.N., Pierce S.K. A role for lipid rafts in B cell antigen receptor signaling and antigen targeting. J. Exp. Med. 190:1999;1549-1560.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1549-1560
-
-
Cheng, P.C.1
Dykstra, M.L.2
Mitchell, R.N.3
Pierce, S.K.4
-
47
-
-
0034601071
-
CD40 signaling in human dendritic cells is initiated within membrane rafts
-
Vidalain P.O., Azocar O., Servet-Delprat C., Rabourdin-Combe C., Gerlier D., Manie S. CD40 signaling in human dendritic cells is initiated within membrane rafts. EMBO J. 19:2000;3304-3313.
-
(2000)
EMBO J.
, vol.19
, pp. 3304-3313
-
-
Vidalain, P.O.1
Azocar, O.2
Servet-Delprat, C.3
Rabourdin-Combe, C.4
Gerlier, D.5
Manie, S.6
-
48
-
-
0034685914
-
Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling
-
Hostager B.S., Catlett I.M., Bishop G.A. Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling. J. Biol. Chem. 275:2000;15392-15398.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15392-15398
-
-
Hostager, B.S.1
Catlett, I.M.2
Bishop, G.A.3
-
50
-
-
0033517301
-
The tyrosine kinase Lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation
-
Belka C., Marini P., Lepple-Wienhues A., Budach W., Jekle A., Los M., Lang F., Schulze-Osthoff K., Gulbins E., Bamberg M. The tyrosine kinase Lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation. Oncogene. 18:1999;4983-4992.
-
(1999)
Oncogene
, vol.18
, pp. 4983-4992
-
-
Belka, C.1
Marini, P.2
Lepple-Wienhues, A.3
Budach, W.4
Jekle, A.5
Los, M.6
Lang, F.7
Schulze-Osthoff, K.8
Gulbins, E.9
Bamberg, M.10
-
51
-
-
0035968191
-
Ceramide enables Fas to cap and kill
-
Cremesti A., Paris F., Grassmé H., Holler N., Tschopp J., Fuks Z., Gulbins E., Kolesnick R. Ceramide enables Fas to cap and kill. J. Biol. Chem. 276:2001;23954-23961.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23954-23961
-
-
Cremesti, A.1
Paris, F.2
Grassmé, H.3
Holler, N.4
Tschopp, J.5
Fuks, Z.6
Gulbins, E.7
Kolesnick, R.8
-
52
-
-
0033613826
-
T lymphocyte costimulation mediated by reorganization of membrane microdomains
-
Viola A., Schroeder S., Sakakibara Y., Lanzavecchia A. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science. 283:1999;680-682.
-
(1999)
Science
, vol.283
, pp. 680-682
-
-
Viola, A.1
Schroeder, S.2
Sakakibara, Y.3
Lanzavecchia, A.4
-
53
-
-
0031693206
-
Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling
-
Natoli G., Costanzo A., Guido F., Moretti F., Levrero M. Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling. Biochem. Pharmacol. 56:1998;915-920.
-
(1998)
Biochem. Pharmacol.
, vol.56
, pp. 915-920
-
-
Natoli, G.1
Costanzo, A.2
Guido, F.3
Moretti, F.4
Levrero, M.5
-
54
-
-
0029879507
-
Localization of platelet-derived growth factor-stimulated phosphorylation cascade in caveolae
-
Liu P., Ying Y., Ko Y.G., Anderson R.G. Localization of platelet-derived growth factor-stimulated phosphorylation cascade in caveolae. J. Biol. Chem. 271:1996;10299-10303.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10299-10303
-
-
Liu, P.1
Ying, Y.2
Ko, Y.G.3
Anderson, R.G.4
-
55
-
-
0027409799
-
Syn-capping of human T lymphocyte adhesion/activation molecules and their redistribution during interaction with endothelial cells
-
Rosenman S.J., Ganji A.A., Tedder T.F., Gallatin W.M. Syn-capping of human T lymphocyte adhesion/activation molecules and their redistribution during interaction with endothelial cells. J. Leukoc. Biol. 53:1993;1-10.
-
(1993)
J. Leukoc. Biol.
, vol.53
, pp. 1-10
-
-
Rosenman, S.J.1
Ganji, A.A.2
Tedder, T.F.3
Gallatin, W.M.4
-
56
-
-
0033043757
-
Intracellular mechanisms of L-selectin induced capping
-
Junge S., Brenner B., Lepple-Wienhues A., Nilius B., Lang F., Linderkamp O., Gulbins E. Intracellular mechanisms of L-selectin induced capping. Cell. Signal. 11:1999;301-308.
-
(1999)
Cell. Signal.
, vol.11
, pp. 301-308
-
-
Junge, S.1
Brenner, B.2
Lepple-Wienhues, A.3
Nilius, B.4
Lang, F.5
Linderkamp, O.6
Gulbins, E.7
-
57
-
-
0028784298
-
Compartmentalized production of ceramide at the cell surface
-
Liu P., Anderson R.G. Compartmentalized production of ceramide at the cell surface. J. Biol. Chem. 270:1995;27179-27185.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27179-27185
-
-
Liu, P.1
Anderson, R.G.2
-
58
-
-
0030891210
-
Association of p75 (NTR) with caveolin and localization of neutrophin-induced sphingomyelin hydrolysis to caveolae
-
Bilderback T.R., Grigsby R.J., Dobrowsky R.T. Association of p75 (NTR) with caveolin and localization of neutrophin-induced sphingomyelin hydrolysis to caveolae. J. Biol. Chem. 272:1997;10922-10927.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10922-10927
-
-
Bilderback, T.R.1
Grigsby, R.J.2
Dobrowsky, R.T.3
-
59
-
-
0037119484
-
Clustering of CD40 ligand is required to form a functional contact with CD40
-
Grassmé H., Bock J., Kun J., Gulbins E. Clustering of CD40 ligand is required to form a functional contact with CD40. J. Biol. Chem. 277:2002;30289-30399.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30289-30399
-
-
Grassmé, H.1
Bock, J.2
Kun, J.3
Gulbins, E.4
-
60
-
-
0034282716
-
CD95-mediated apoptosis in vivo involves acid sphingomyelinase
-
Kirschnek S., Paris F., Weller M., Grassmé H., Ferlinz K., Riehle A., Fuks Z., Kolesnick R., Gulbins E. CD95-mediated apoptosis in vivo involves acid sphingomyelinase. J. Biol. Chem. 275:2000;27316-27323.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27316-27323
-
-
Kirschnek, S.1
Paris, F.2
Weller, M.3
Grassmé, H.4
Ferlinz, K.5
Riehle, A.6
Fuks, Z.7
Kolesnick, R.8
Gulbins, E.9
-
61
-
-
0035191769
-
Lipopolysaccharide and ceramide docking to CD14 provokes ligand-specific receptor clustering in rafts
-
Pfeifer A., Böttcher A., Orso E., Kapinsky M., Nagy P., Bodnar A., Spreitzer I., Liebisch G., Dobnik W., Gempel K., Horn M., Holmer S., Hartung T., Multhoff G., Schütze G., Schindler H., Ulmer A.J., Heine H., Stelter F., Schütt C., Rothe G., Szöllosi J., Damjanovich S., Schmitz G. Lipopolysaccharide and ceramide docking to CD14 provokes ligand-specific receptor clustering in rafts. Eur. J. Immunol. 31:2001;3153-3164.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 3153-3164
-
-
Pfeifer, A.1
Böttcher, A.2
Orso, E.3
Kapinsky, M.4
Nagy, P.5
Bodnar, A.6
Spreitzer, I.7
Liebisch, G.8
Dobnik, W.9
Gempel, K.10
Horn, M.11
Holmer, S.12
Hartung, T.13
Multhoff, G.14
Schütze, G.15
Schindler, H.16
Ulmer, A.J.17
Heine, H.18
Stelter, F.19
Schütt, C.20
Rothe, G.21
Szöllosi, J.22
Damjanovich, S.23
Schmitz, G.24
more..
-
62
-
-
0033965898
-
Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide
-
Zundel W., Swiersz L.M., Giaccia A. Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide. Mol. Cell. Biol. 20:2000;1507-1514.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1507-1514
-
-
Zundel, W.1
Swiersz, L.M.2
Giaccia, A.3
-
63
-
-
0032536876
-
Acidic sphingomyelinase (ASM) is necessary for Fas-induced CD3 ganglioside accumulation and efficient apoptosis of lymphoid cells
-
De Maria R., Rippo M.R., Schuchman E.H., Testi R. Acidic sphingomyelinase (ASM) is necessary for Fas-induced CD3 ganglioside accumulation and efficient apoptosis of lymphoid cells. J. Exp. Med. 187:1998;897-902.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 897-902
-
-
De Maria, R.1
Rippo, M.R.2
Schuchman, E.H.3
Testi, R.4
-
64
-
-
0033786639
-
Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy
-
Morita Y., Perez G.I., Paris F., Miranda S.R., Ehleiter D., Haimovitz-Friedman A., Fuks Z., Xie Z., Reed J.C., Schuchman E.H., Kolesnick R.N., Tilly J.L. Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy. Nat. Med. 6:2000;1109-1114.
-
(2000)
Nat. Med.
, vol.6
, pp. 1109-1114
-
-
Morita, Y.1
Perez, G.I.2
Paris, F.3
Miranda, S.R.4
Ehleiter, D.5
Haimovitz-Friedman, A.6
Fuks, Z.7
Xie, Z.8
Reed, J.C.9
Schuchman, E.H.10
Kolesnick, R.N.11
Tilly, J.L.12
-
65
-
-
0030774818
-
CD95/Fas-induced ceramide formation proceeds with slow kinetics and is not blocked by caspase 3/CPP32 inhibition
-
Tepper A.D., Cock J.G., de Vries E., Borst J., Blitterswijk W.J. CD95/Fas-induced ceramide formation proceeds with slow kinetics and is not blocked by caspase 3/CPP32 inhibition. J. Biol. Chem. 272:1997;24308-24312.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24308-24312
-
-
Tepper, A.D.1
Cock, J.G.2
De Vries, E.3
Borst, J.4
Blitterswijk, W.J.5
-
66
-
-
0035808364
-
Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts
-
Lozano J., Menendez S., Morales A., Ehleiter D., Liao W.C., Wagman R., Haimovitz-Friedman A., Fuks Z., Kolesnick R. Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts. J. Biol. Chem. 276:2001;442-448.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 442-448
-
-
Lozano, J.1
Menendez, S.2
Morales, A.3
Ehleiter, D.4
Liao, W.C.5
Wagman, R.6
Haimovitz-Friedman, A.7
Fuks, Z.8
Kolesnick, R.9
-
67
-
-
0035896515
-
Natural ceramide reverses Fas resistance of acid sphingomyelinase (-/-) hepatocytes
-
Paris F., Grassmé H., Cremesti A., Zager J., Fong Y., Haimovitz-Friedman A., Fuks Z., Gulbins E., Kolesnick R. Natural ceramide reverses Fas resistance of acid sphingomyelinase (-/-) hepatocytes. J. Biol. Chem. 276:2000;8297-8305.
-
(2000)
J. Biol. Chem.
, vol.276
, pp. 8297-8305
-
-
Paris, F.1
Grassmé, H.2
Cremesti, A.3
Zager, J.4
Fong, Y.5
Haimovitz-Friedman, A.6
Fuks, Z.7
Gulbins, E.8
Kolesnick, R.9
-
68
-
-
0035137630
-
Niemann-Pick disease versus acid sphingomyelinase deficiency
-
Lozano J., Morales A., Cremesti A., Fuks Z., Tilly J.L., Schuchman E., Gulbins E., Kolesnick R. Niemann-Pick disease versus acid sphingomyelinase deficiency. Cell Death Differ. 8:2001;100-103.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 100-103
-
-
Lozano, J.1
Morales, A.2
Cremesti, A.3
Fuks, Z.4
Tilly, J.L.5
Schuchman, E.6
Gulbins, E.7
Kolesnick, R.8
-
69
-
-
0012515044
-
Perturbation of membrane microdomains reduces mitogenic signaling and increases susceptibility to apoptosis after T cell receptor stimulation
-
Nix M., Stoffel W. Perturbation of membrane microdomains reduces mitogenic signaling and increases susceptibility to apoptosis after T cell receptor stimulation. Cell Death Differ. 8:2001;100-103.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 100-103
-
-
Nix, M.1
Stoffel, W.2
-
70
-
-
0030736420
-
Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase
-
Huang C., Wy M., Ding M., Bowden G.T., Dong Z. Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase. J. Biol. Chem. 272:1997;27753-27757.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27753-27757
-
-
Huang, C.1
Wy, M.2
Ding, M.3
Bowden, G.T.4
Dong, Z.5
-
71
-
-
0342545909
-
Radiation-induced apoptosis of endothelial cells in the murine central nervous system: Protection by fibroblast growth factor and sphingomyelinase deficiency
-
Pena L.A., Fuks Z., Kolesnick R.N. Radiation-induced apoptosis of endothelial cells in the murine central nervous system: protection by fibroblast growth factor and sphingomyelinase deficiency. Cancer Res. 60:2000;321-327.
-
(2000)
Cancer Res.
, vol.60
, pp. 321-327
-
-
Pena, L.A.1
Fuks, Z.2
Kolesnick, R.N.3
-
72
-
-
0035854479
-
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
-
Paris F., Fuks Z., Kang A., Capodieci P., Juan G., Ehleiter D., Haimovitz-Friedman A., Cordon-Cardo C., Kolesnick R. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science. 293:2001;293-297.
-
(2001)
Science
, vol.293
, pp. 293-297
-
-
Paris, F.1
Fuks, Z.2
Kang, A.3
Capodieci, P.4
Juan, G.5
Ehleiter, D.6
Haimovitz-Friedman, A.7
Cordon-Cardo, C.8
Kolesnick, R.9
|