A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions

Oncogene

Volumn 21, Issue 37, 2002, Pages 5704-5715

  Inga, Alberto ^a   Nahari, Dorit ^b   Velasco Miguel, Susana ^b   Friedberg, Errol C ^b   Resnick, Michael A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Enhanced transactivation; Mutational hotspots; P53 expression; P53 gene; Xpc mice; Yeast functional assay

Indexed keywords

PROTEIN BAX; PROTEIN MDM2; PROTEIN P21; PROTEIN P53;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; EXCISION REPAIR; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN TISSUE; ONCOGENE C FOS; PRIORITY JOURNAL; SKIN TUMOR; TRANSACTIVATION; ULTRAVIOLET IRRADIATION;

ALLELES; ANIMALS; APOPTOSIS; DNA DAMAGE; DNA-BINDING PROTEINS; G1 PHASE; GENES, P53; MICE; MUTATION; SKIN NEOPLASMS; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

MAMMALIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037158903     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205779     Document Type: Article

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