Structure-Function of the Putative I-domain within the Integrin β 2 Subunit

Journal of Biological Chemistry

Volumn 276, Issue 22, 2001, Pages 19340-19349

  Xiong, Yu Mei ^b   Zhang, Li ^a  

^a HOLLAND LABORATORY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DIMERS; HYDROPHILICITY; MUTAGENESIS; PROTEINS; SUBSTITUTION REACTIONS;

HETERODIMERS; LIGANDS;

BIOCHEMISTRY;

ALPHAM BETA2 INTEGRIN; BETA2 INTEGRIN; BETA3 INTEGRIN; CALCIUM ION; EPITOPE; GLUTAMIC ACID; MONOCLONAL ANTIBODY; MUTANT PROTEIN; PROLINE; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; CALCIUM; CD18 ANTIGEN; LIGAND;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DIMERIZATION; EPITOPE MAPPING; HUMAN; HUMAN CELL; HYDROPHILICITY; LIGAND BINDING; MOLECULAR RECOGNITION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; CELL ADHESION; CELL LINE; CELL SEPARATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; FLOW CYTOMETRY; GENETIC TRANSFECTION; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANTIGENS, CD18; BINDING SITES; CALCIUM; CELL ADHESION; CELL LINE; CELL SEPARATION; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITOPE MAPPING; EPITOPES; FLOW CYTOMETRY; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0035377569     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008903200     Document Type: Article

References (65)

1. Plow, E. F., Haas, T. A., Zhang, L., Loftus, J. C., and Smith, J. W. (2000) J. Biol. Chem. 275, 21785-21788
2. Springer, T. A. (1995) Annu. Rev. Physiol. 57, 827-872
3. Altieri, D. C., Bader, R., Mannucci, P. M., and Edgington, T. S. (1988) J. Cell Biol. 107, 1893-1900
4. Diamond, M. S., Staunton, D. E., de Fougerolles, A. R., Stacker, S. A., Garcia-Aguilar, J., Hibbs, M. L., and Springer, T. A. (1990) J. Cell Biol. 111, 3129-3139
5. Wright, S. D., Rao, P. E., Van Voorhis, W. C., Craigmyle, L. S., Iida, K., Talle, M. A., Westberg, E. F., Goldstein, G., and Silverstein, S. C. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 5699-5703
6. Ross, G. D., Cain, J. A., and Lachmann, P. J. (1985) J. Immunol. 134, 3307-3315
7. Moyle, M., Foster, D. L., McGrath, D. E., Brown, S. M., Laroche, Y., De Meutter, J., Bogowitz, C. A., Fried, V. A., and Ely, J. A., (1994) J. Biol. Chem. 269, 10008-10015
8. Ugarova, T. P., Sotovjov, D. A., Zhang, L., Loukinov, D. I., Yee, V. C., Medved, L. V., and Plow, E. F. (1998) J. Biol. Chem. 273, 22519-22527
9. Michishita, M., Videm, V., and Arnaout, M. A. (1993) Cell 72, 857-867
10. Lee, J. O., Rieu, P., Arnaout, M. A., and Liddington, R. C. (1995) Cell 80, 631-638
11. Qu, A., and Leahy, D. J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10277-10281
12. Emsley, J., King, S. L., Bergelson, J. M., and Liddington, R. C. (1997) J. Biol. Chem. 272, 28512-28517
13. Emsley, J., Knight, C. G., Farndale, R. W., Barnes, M. J., and Liddington, R. C. (2000) Cell 101, 47-56
14. Lin, C. K. E., Ratnikov, B. I., Tsai, P. M., Gonzalez, E. R., McDonald, S., Pelletier, A. J., and Smith, J. W. (1997) J. Biol. Chem. 272, 14236-14243
15. Puzon-McLaughlin, W., and Takada, Y. (1996) J. Biol. Chem. 271, 20438-20443
16. Tozer, E. C., Liddington, R. C., Sutcliffe, M. J., Smeeton, A. H., and Loftus, J. C. (1996) J. Biol. Chem. 271, 21978-21984
17. Goodman, T. G., and Bajt, M. L. (1996) J. Biol. Chem. 271, 23729-23736
18. Tuckwell, D. S., and Humphries, M. J. (1997) FEBS Lett. 400, 297-303
19. D'Souza, S. E., Ginsberg, M. H., Burke, T. A., Lam, S. C. T., and Plow, E. F. (1988) Science 242, 91-93
20. Smith, J. W., and Cheresh, D. A. (1988) J. Biol. Chem. 263, 18726-18731
21. Lin, E. C., Ratnikov, B. I., Tsai, P. M., Carron, C. P., Myers, D. M., Barbas, C. F., and Smith, J. W. (1997) J. Biol. Chem. 272, 23912-23920
22. Takagi, J., Kamata, T., Meredith, J., Puzon-McLaughlin, W., and Takada, Y. (1997) J. Biol. Chem. 272, 19794-19800
23. Bajt, M. L., Ginsberg, M. H., Frelinger, A. L., III, Berndt, M. C., and Loftus, J. C. (1992) J. Biol. Chem. 267, 3789-3794
24. Shih, D. T., Boettiger, D., and Buck, C. A. (1997) J. Cell Sci. 110, 2619-2628
25. Takada, Y., and Puzon, W. (1993) J. Biol. Chem. 268, 17597-17601
26. Bajt, M. L., Goodman, T. G., and McGuire, S. L. (1995) J. Biol. Chem. 270, 94-98
27. Zhang, L., and Plow, E. F. (1996) J. Biol. Chem. 271, 18211-18216
28. Cunningham, B. C., Jhurani, P., Ng, P., and Wells, J. A. (1989) Science 243, 1330-1336
29. Zhang, L., and Plow, E. F. (1999) Biochemistry 38, 8064-8071
30. Zhang, L., and Plow, E. F. (1997) J. Biol. Chem. 272, 17558-17564
31. Arnaout, M. A., Dana, N., Gupta, S. K., Tenen, D. G., and Fathallah, D. M. (1990) J. Clin. Invest. 85, 977-981
32. Wardlaw, A. J., Hibbs, M. L., Stacker, S. A., and Springer, T. A. (1990) J. Exp. Med. 172, 335-345
33. Back, A. L., Kwok, W. W., and Hickstein, D. D. (1992) J. Biol. Chem. 267, 5482-5487
34. Corbi, A. L., Vara, A., Ursa, A., Garcia, R. M., Fontan, G., and Sanchez-Madrid, F. (1992) Eur. J. Immunol. 22, 1877-1881
35. Matsuura, S., Kishi, F., Tsukahara, M., Nunoi, H., Matsuda, I., Kobayashi, K., and Kajii, T. (1992) Biochem. Biophys. Res. Commun. 184, 1460-1467
36. Nelson, C., Rabb, H., and Arnaout, M. A. (1992) J. Biol. Chem. 267, 3351-3357
37. Hogg, N., Stewart, M. P., Scarth, S. L., Newton, R., Shaw, J. M., Law, S. K., and Klein, N. (1999) J. Clin. Invest. 103, 97-106
38. Lorenz, H. M., Harrer, T., Lagoo, A. S., Baur, A., Eger, G., and Kalden, J. R. (1993) Cell. Immunol. 147, 110-128
39. McNally, A. K., and Anderson, J. M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10119-10123
40. Lindbom, L., Lundberg, C., Prieto, J., Raud, J., Nortamo, P., Gahmberg, C. G., and Patarroyo, M. (1990) Clin. Immunol. Immunopathol. 57, 105-119
41. Marr, K. A., Lees, P., and Cunningham, F. M. (1999) Vet. Immunol. Immunopathol. 71, 77-88
42. Huang, C., Zang, Q., Takagi, J., and Springer, T. A. (2000) J. Biol. Chem. 275, 21514-21524
43. Puzon-McLaughlin, W., Kamata, T., and Takada, Y. (2000) J. Biol. Chem. 275, 7795-7802
44. Lee, J. O., Bankston, L. A., Arnaout, M. A., and Liddington, R. C. (1995) Structure 3, 1333-1340
45. Griggs, D. W., Schmidt, C. M., and Carron, C. P. (1998) J. Biol. Chem. 273, 22113-22119
46. Mould, A. P., Garratt, A. N., Puzon-McLaughlin, W., Takada, Y., and Humphries, M. J. (1998) Biochem. J. 331, 821-828
47. Baneres, J. L., Roquet, F., Martin, A., and Parello, J. (2000) J. Biol. Chem. 275, 5888-5903
48. Ueda, T., Rieu, P., Brayer, J., and Arnaout, M. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10680-10684
49. Dransfield, I., Cabanas, C., Craig, A., and Hogg, N. (1992) J. Cell Biol. 116, 219-226
50. Gotwals, P. J., Chi-Rosso, G., Ryan, S. T., Sizing, I., Zafari, M., Benjamin, C., Singh, J., Venyaminov, S. Y., Pepinsky, R. B., and Koteliansky, V. (1999) Biochemistry 38, 8280-8288
51. McKay, B. S., Annis, D. S., Honda, S., Christie, D., and Kunicki, T. J. (1996) J. Biol. Chem. 271, 30544-30547
52. Douglass, W. A., Hyland, R. H., Buckley, C. D., Al-Shamkhani, A., Shaw, J. M., Scarth, S. L., Simmons, D. L., and Law, S. K. (1998) FEBS Lett. 440, 414-418
53. Wippler, J., Kouns, W. C., Schlaeger, E. J., Kuhn, H., Hadvary, P., and Steiner, B. (1994) J. Biol. Chem. 269, 8754-8761
54. Springer, T. A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 65-72
55. Mould, A. P., Akiyama, S. K., and Humphries, M. J. (1996) J. Biol. Chem. 271, 20365-20374
56. Lu, C. F., and Springer, T. A. (1997) J. Immunol. 159, 268-278
57. Vetvicka, V., Thornton, B. P., and Ross, G. D. (1996) J. Clin. Invest. 98, 50-61
58. Kamata, T., Puzon, W., and Takada, Y. (1994) J. Biol. Chem. 269, 9659-9663
59. Kern, A., Briesewitz, R., Bank, I., and Marcantonio, E. E. (1994) J. Biol. Chem. 269, 22811-22816
60. Huang, C., and Springer, T. A. (1995) J. Biol. Chem. 270, 19008-19016
61. Kamata, T., Wright, R., and Takada, Y. (1995) J. Biol. Chem. 270, 12531-12535
62. Cierniewski, C. S., Byzova, T., Papierak, M., Haas, T. A., Niewiarowska, J., Zhang, L., Cieslak, M., and Plow, E. F. (1999) J. Biol. Chem. 274, 16923-16932
63. Bazzoni, G., Shih, D.-T., Buck, C. A., and Hemler, M. E. (1995) J. Biol. Chem. 270, 25570-25577
64. Bajt, M. L., and Loftus, J. C. (1994) J. Biol. Chem. 269, 20913-20919
65. Mould, A. P., Akiyama, S. K., and Humphries, M. J. (1995) J. Biol. Chem. 270, 26270-26277