Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the mouse melanocortin receptors. 1. Modifications at the his position

Journal of Medicinal Chemistry

Volumn 45, Issue 13, 2002, Pages 2801-2810

  Holder, Jerry Ryan ^a   Bauzo, Rayna M ^a   Xiang, Zhimin ^a   Haskell Luevano, Carrie ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 PYRIDINYL)ALANINE; ACETYLAMINO 3 (2 THIENYL)ALANINE DEXTRO PHENYLALANYLARGINYLTRYPTOPHANAMINE; ACETYLHISTIDYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHANAMINE; AMINO 2 NAPHTHYLCARBOXYLIC ACID; AMINO ACID DERIVATIVE; BETA (2 THIENYL)ALANINE; HISTIDINE; IMIDAZOLE DERIVATIVE; MELANOCORTIN; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 5 RECEPTOR; MELANOCORTIN RECEPTOR; PEPTIDE LIBRARY; TETRAPEPTIDE; UNCLASSIFIED DRUG;

AGONIST; AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL MODIFICATION; CHIRALITY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ALPHA-MSH; ANIMALS; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; HISTIDINE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RECEPTOR, MELANOCORTIN, TYPE 3; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, CORTICOTROPIN; RECEPTORS, MELANOCORTIN; RECEPTORS, PEPTIDE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037142333     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0104872     Document Type: Article

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