An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits

Neuropharmacology

Volumn 41, Issue 6, 2001, Pages 714-723

  Xia, H ^a   Hornby, Z D ^a   Malenka, R C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; CD8 ANTIGEN; CELL PROTEIN; HYBRID PROTEIN; MEMBRANE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL STRAIN; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HIPPOCAMPUS; LYMPHOCYTE MEMBRANE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SYNAPSE;

ANIMALS; ANTIGENS, CD8; CELL MEMBRANE; CELLS, CULTURED; ENDOPLASMIC RETICULUM; HIPPOCAMPUS; HUMANS; MUTAGENESIS, INSERTIONAL; NEURONS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; RECOMBINANT FUSION PROTEINS; SYNAPSES;

EID: 0034788270     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00103-4     Document Type: Article

References (32)

1. ER protein quality control and proteasome-mediated protein degradation
2. Role of AMPA receptor endocytosis in synaptic plasticity
3. Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins
4. Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons
5. GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors
6. Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering
7. Setting the standards: Quality control in the secretory pathway
8. PDZ domains in synapse assembly and signalling
9. Cloned glutamate receptors
10. Subtype-specific assembly of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits is mediated by their n-terminal domains
11. The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes
12. Role of AMPA receptor cycling in synaptic transmission and plasticity
13. LTP mechanisms: From silence to four-lane traffic
14. A trafficking checkpoint controls GABA(B) receptor heterodimerization
15. Phosphorylation of serine-880 in GluR2 by protein kinase C prevents its C terminus from binding with glutamate receptor-interacting protein
16. Assembly intracellular targeting and cell surface expression of the human N-methyl-D-aspartate receptor subunits NR1a and NR2A in transfected cells
17. Cell surface expression of the human N-methyl-D-aspartate receptor subunit 1a requires the co-expression of the NR2A subunit in transfected cells
18. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
19. Alternative splicing of the C-terminal domain regulates cell surface expression of the NMDA receptor NR1 subunit
20. An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing
21. PDZ domains and the organization of supramolecular complexes
22. PDZ domain suppression of an ER retention signal in NMDA receptor NR1 splice variants
23. Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the golgi apparatus
24. Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies
25. N-terminal palmitoylation of PSD-95 regulates association with cell membranes and interaction with K+ channel Kv1.4
26. The nicotinic acetylcholine receptor at the neuromuscular junction: Assembly and tyrosine phosphorylation
27. Assembly of the nicotinic acetylcholine receptor. The first transmembrane domains of truncated alpha and delta subunits are required for heterodimer formation in vivo
28. Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons
29. Mammalian ionotropic glutamate receptors
30. Actinin-associated LIM protein: Identification of a domain interaction between PDZ and spectrin-like repeat motifs
31. A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels
32. Synaptic clustering of Fascilin II and Shaker: Essential targeting sequences and role of Dlg