Treatment with a monoclonal antibody to IL-8 attenuates the pleocytosis in experimental pneumococcal meningitis in rabbits when given intravenously, but not intracisternally

Clinical and Experimental Immunology

Volumn 122, Issue 2, 2000, Pages 207-211

  Stergaard, C ^a   Yieng Kow, R V ^a   Larsen, C G ^b   Mukaida, N ^c   Matsushima, K ^d   Benfield, T ^e   Frimodt Moller N ^a   Espersen, F ^a   Kharazmi, A ^f   Lundgren, J D ^e  

^a STATENS SERUM INSTITUT   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c KANAZAWA UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e HVIDOVRE HOSPITAL   (Denmark)

^f University of Copenhagen   (Denmark)

Author keywords

IL 8; Meningitis; Streptococcus pneumoniae

Indexed keywords

INTERLEUKIN 8; MONOCLONAL ANTIBODY; RECOMBINANT INTERLEUKIN 8;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL MENINGITIS; BRAIN; CEREBROSPINAL FLUID ANALYSIS; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG EFFICACY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PLEOCYTOSIS; PRIORITY JOURNAL; RABBIT; STREPTOCOCCUS PNEUMONIAE; VASCULAR ENDOTHELIUM; ANIMAL; CEREBROSPINAL FLUID; CISTERNA MAGNA; COMPARATIVE STUDY; DRUG ANTAGONISM; IMMUNOLOGY; INJECTION; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTOSIS; VASCULARIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN; CISTERNA MAGNA; ENDOTHELIUM, VASCULAR; INJECTIONS; INJECTIONS, INTRAVENOUS; INTERLEUKIN-8; LEUKOCYTOSIS; MENINGITIS, PNEUMOCOCCAL; RABBITS;

EID: 0033623579     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01357.x     Document Type: Article

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