Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni

Free Radical Biology and Medicine

Volumn 32, Issue 4, 2002, Pages 319-332

  El Sokkary, Gamal H ^a   Omar, Hosam M ^a   Hassanein, Abdel Fattah M M ^a   Cuzzocrea, Salvatore ^b   Reiter, Russel J ^c,d  

^a Assiut University   (Egypt)

^b UNIVERSITY OF MESSINA   (Italy)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Free radicals; Glutathione; Lipid peroxidation; Melatonin; Oxidative stress; Schistosoma mansoni; Superoxide dismutase

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; ANION; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; DILUENT; FREE RADICAL; GLUTATHIONE; MELATONIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; PROTEIN; SUPEROXIDE DISMUTASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DEATH; CELL INFILTRATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG EFFICACY; ENZYME ACTIVITY; EOSINOPHIL; GRANULOMATOUS INFLAMMATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY TUBULE; LIPID PEROXIDATION; LIVER; LIVER INJURY; MALE; MEGAKARYOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SPLEEN; STAINING; SURVIVAL RATE; TISSUE LEVEL; ANIMAL; CYTOLOGY; METABOLISM; PARASITOLOGY; PATHOGENICITY; TIME; TISSUE DISTRIBUTION;

ALKALINE PHOSPHATASE; ANIMAL; ANTIOXIDANTS; FREE RADICALS; GLUTATHIONE; IMMUNOHISTOCHEMISTRY; KIDNEY; LIPID PEROXIDATION; MALE; MEGAKARYOCYTES; MELATONIN; MICE; NITRIC OXIDE; NITRIC-OXIDE SYNTHASE; OXIDATIVE STRESS; SCHISTOSOMA MANSONI; SPLEEN; SUPEROXIDE DISMUTASE; TIME FACTORS; TISSUE DISTRIBUTION; VITAMIN E; ANIMALS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II;

SCHISTOSOMA; SCHISTOSOMA MANSONI;

EID: 0037082351     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00753-5     Document Type: Article

References (75)

1. Role of cell-generated hydrogen peroxide in granulocyte-mediated killing of schistosomula of Schistosoma mansoni in vitro
2. Role of granulocyte oxygen products in damage of Schistosoma mansoni eggs in vitro
3. Ultrastructure of the attack eosinophils stimulated by blood mononuclear cell products on schistosomula of Schistosoma mansoni
4. Eosinophils from schistosome-induced hepatic granulomas produce superoxide and hydroxyl radical
5. Visualization of oxygen radical production in mouse liver in response to infection with Schistosoma mansoni
6. Development of eosinophil peroxidase activity and concomitant alteration of the antioxidant defenses in the liver of mice infected with Schistosoma mansoni
7. Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role of nitric oxide
8. A pilot study of the effects of d-α-tocopherol on hepatic stellate cells activation in chronic hepatitis C
9. Oxidative damage and fibrogenesis
10. Noninvasive diagnosis of hepatic fibrosis or cirrhosis
11. Endocytosis of hyaluronic acid by rat liver endothelial cells: Evidence for receptor recycling
12. Melatonin: A potent, endogenous hydroxyl radical scavenger
13. Melatonin: Its intracellular and genomic actions
14. Suppression of oxygen toxicity by melatonin
15. The oxidant/antioxidant network: Role of melatonin
16. Oxidative damage in the central nervous system: Protection by melatonin
17. 3
18. Significance of melatonin in antioxidative defense system: Reactions and products
19. Melatonin protects against stress-induced gastric lesions by scavenging the hydroxyl radical
20. Scavenging effect of melatonin on hydroxyl radical generated by alloxan
21. Scavenging of reactive oxygen species by melatonin
22. Nitrosation of melatonin by nitric oxide: A computational study
23. Nitrosation of melatonin by nitric oxide and peroxynitrite
24. Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in nonseptic shock induced by zymosan
25. Melatonin directly scavenges hydrogen peroxide: A potentially new metabolic pathway of melatonin biotransformation
26. Administration of melatonin and related indoles prevents exercise-induced cellular oxidative changes in rats
27. Pharmacological actions of melatonin in oxygen radical pathophysiology
28. Melatonin enhances tamoxifin's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation
29. Actions of melatonin in the reduction of oxidative stress: A review
30. Melatonin, mitochondria, and cellular bioenergetics
31. Microsomal lipid peroxidation
32. Measurement of vitamin E
33. Release of reactive nitrogen intermediates and reactive oxygen intermediates from peritoneal macrophages
34. Improved method for the determination of blood glutathione
35. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase
36. A colorimetric determination of serum glutamic oxaloacetic and glutamic pyrucic transaminase
37. Protein measurement with Folin phenol reagent
38. Protective effect of melatonin in carrageenan-induced models of local inflammation: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity
39. The superoxide-generating oxidase of phagocytic cells. Physiological, molecular and pathological aspects
40. Long-lived oxidants generated by human neutrophils: Characterization and bioactivity
41. Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolin
42. Microvesicular steatosis and steatohepatitis: Role of mitochondrial dysfunction and lipid peroxidation
43. Stimulation of collagen α 1(I) gene expression is associated with lipid peroxidation in hepatocellular injury: A link to tissue fibrosis?
44. On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis
45. Elevated type 1, diminished type 2 cytokines, and impaired antibody response are associated with hepatotoxicity and mortalities during Schistosoma mansoni infection of CD4-depleted mice
46. Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytes
47. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
48. Protective role of intracellular superoxide dismutase against extracellular oxidants in cultured rat gastric cells
49. Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide
50. The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury
51. Peroxynitrite-mediated DNA strand breakage activates poly-adensine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide
52. The arginine-nitric oxide pathway
53. Invited opinion: Role of nitric oxide in hemorrhagic, traumatic, and anaphylactic shock and thermal injury
54. IL-4 plays a crucial role in regulating oxidative damage in the liver during schistosomiasis
55. Permeability of pure lipid bilayers to melatonin
56. High melatonin solubility in aqueous medium
57. Delta-aminolevulenic acid-induced lipid peroxidation in rat kidney and liver is attenuated by melatonin: An in vitro and in vivo study
58. Protective effect of melatonin on indomethacin-induced gastric injury in rats
59. Inhibitory effect of melatonin on products of lipid peroxidation resulting from chronic ethanol administration
60. Protective effect of melatonin on zymosan-induced cellular damage
61. Melatonin protects against ischemia- and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain
62. Effects of melatonin on DNA damage and repair in rat brain following a transient cerebral ischemia
63. Distribution of melatonin in inmammalian tissues: Relative importance of nuclear vs. cytosolic localization
64. Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence
65. Antioxidative protection in a high-melatonin organism: The dinoflagellate Gonyaulax polydra is reduced from lethal stress by strongly elevated, but physiologically possible concentrations of melatonin
66. Melatonin protects human red blood cells from oxidative hemolysis: New insights into the radical scavenging activity
67. 3+-EDTA: Comparison with glutathione and α-tocopherol
68. Melatonin induces γ-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells
69. Rhythms of glutathione peroxidase and glutathione reductase in the brain of chick and their inhibition by light
70. Melatonin increases gene expression for antioxidative enzymes in rat brain cortex
71. Neurohormone melatonin prevents cell damage: Effect on gene expression for antioxidative enzymes
72. Melatonin stimulates brain glutathione peroxidase activity
73. Melatonin is a scavenger of peroxynitrite
74. Reaction of peroxynitrite with melatonin: A mechanistic study
75. Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin