Administration of melatonin and related indoles prevents exercise-induced cellular oxidative changes in rats

NeuroSignals

Volumn 6, Issue 2, 1997, Pages 90-100

  Hara, Masayuki ^a   Iigo, Masayuki ^a   Ohtani Kaneko, Ritsuko ^a   Nakamura, Naoko ^a   Suzuki, Takuro ^a   Reiter, Russel J ^b   Hirata, Kazuaki ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

5 Methoxytryptamine; 6 Hydroxymelatonin; Brain; Liver; Melatonin; Oxidative stress; Skeletal muscle

Indexed keywords

5 METHOXYTRYPTAMINE; 6 HYDROXYMELATONIN; FREE RADICAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; INDOLEAMINE; MALONALDEHYDE; MELATONIN; SCAVENGER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; EXERCISE; LIPID PEROXIDATION; LIVER; MUSCLE LEVEL; NONHUMAN; OXIDATION; OXIDATIVE STRESS; RAT; SWIMMING;

5-METHOXYTRYPTAMINE; ANIMALS; BRAIN; EXERTION; FREE RADICALS; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; LIVER; MALE; MELATONIN; MUSCLE, SKELETAL; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SWIMMING;

ANIMALIA; LETHRINIDAE;

EID: 0030844416     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000109113     Document Type: Article

References (46)

1. Vivien-Roels B, Pevel P: Is melatonin an evolutionary conservative molecule involved in the transduction of photoperiodic information in all living organisms?; in Reiter RJ, Karasek M (eds); Advances in Pineal Research. London, Libbey, 1986. vol I, pp61-68.
2. Reiter RJ; Melatonin; That ubiquitously acting pineal hormone. News Physiol Sci 1991;6:223-227.
3. Hardeland R, Reiter RJ, Poeggeler B, Tan DX: The significance of the metabolism of the ncurohormonc melatonin: Antioxidativc protection and formation of bioactive substances. Neurosci Biobchav Rev 1993;17:374-357.
4. Axelrod J, Weissbach H: Enzymatic O-methylation of N-acctylseronton-in to melatonin. Science 1960:131; 1312.
5. Axelrod J, Weissbach H: Purification and properties of hydroxy-indole-O-mcthyltransferase. J Biol Chem 1961;236:211-213.
6. Cardinali DP, Wurtman RJ: Hy-droxyindole-O-methyltransferase in rat pineal, retina and Harderian gland. Endocrinology 1972;91:247-252.
7. Reiter RJ, Vaughan MK: A study of indoles which inhibit pineal anti-gonadotrophic activity in male hamsters. Endocr ResCommun 1975;2: 299-308.
8. Reiter RJ, Holtorf A, Champney TH, Vaughan MK: Relative efficacy of melatonin and 5-methoxytryp-tamine in terms of their antigonado-trophic and counterantigonado-trophic actions in male Syrian hamsters. J Pineal Res 1984; 1:91-98.
9. Pevet P, Haldar-Misra C, Ocal T: Effect of 5-methoxytryptophan and 5-methoxytryptamine on the reproductive system of the male golden hamsters. J Neural Transm 1981;51: 303-311.
10. Rollag MD: Ability of tryptophan derivatives to mimic melatonin’s action upon the Syrian hamster reproductive system. Life Sci 1982;31: 2699-2707.
11. Vaughan MK, Vaughan GM, Reiter RJ: Inhibition of chorionic gonadotrophin-induced hypertrophy of the ovaries and uterus in immature mice by some indoles, 6-hydroxy-melatonin and arginine vasotocin. J Endocrinol 1976;68:397-400.
12. Pierpoali W, Dall’ara A, Pcdrinis E, Regelson W: The pineal control of aging: The effects of melatonin and pineal grafting on the survival of older mice. Ann NY Acad Sci 1991; 621:291-313.
13. Reiter RJ, Poeggeler B, Tan DX, Chen LD, Manchester LC, Guerrero JM: Antioxidant capacity of melatonin: A novel action not requiring a receptor. Neuroendocrinol Lett 1993;15:103-116.
14. Tan DX, Chen LD, Poeggeler B, Manchester LC, Reiter RJ: Melatonin: A potent, endogenous hydroxyl radical scavenger. Endocr J 1993;1:57-60.
15. Blickenstaff RT, Brandstadtcr SM, Reddy S, Witt R: Potential radio-protective agents. I. Homologs of melatonin. J Pharm Sci 1994;83: 216-218.
16. Hara M, Abe M, Suzuki T, Reiter RJ: Tissue changes in glutathione metabolism and lipid peroxidation induced by swimming are partially prevented by melatonin. Pharmacol Toxicol 1996;78:308-312.
17. Mclchiorri D, Reiter RJ, Attia AM, Hara M, Nislico G: Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats. Life Sci 1995;56:83-89.
18. Griffith OW: Glutathione and glutathione disulphide; in Bergmeyer HU (ed): Methods of Enzymatic Analysis, ed 3. Wcinheim, VCH Verlags-gescllschaft, 1985, pp 265-275.
19. Estcrbaucr H, Chccseman KH: Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. Methods Enzymol 1990;186:407-421.
20. Jaskot RH, Charlet EG, Grose EC, Grady MA: An automated analysis of glutathione peroxidase, S-trans-ferase, and reductase activity in animal tissue. J Anal Toxicol 1983;7: 86-88.
21. Lowry OH, Rosebrough NJ, Farr AL. Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
22. Ji LL, Dillon D, Wu E: Alteration of antioxidant enzymes with aging in rat skeletal muscle and liver. Am J Physiol 1990;258:R918-R923.
23. Ji LL, Fu R: Responses of glutathione system and antioxidant enzymes to exhaustive exercise and hydroperoxide. J Appl Physiol 1992; 72:549-554.
24. Laughlin MH, Simpson T, Sexton WL, Brown OR, Smith JK, Korthuis RJ: Skeletal muscle oxidative capacity, antioxidant enzymes, and exercise training. J Appl Physiol 1990; 68:2337-2343.
25. Lew H, Pyke S, Quintanilha A: Change in the glutathione status of plasma, liver and muscle following exhaustive exercise in rats. FEBS Lett 1985;185:262-266.
26. Sastrc J, Asensi M, Gasco E, Pallar-do FV, Ferrero JA, Furukawa T, Vina J: Exhaustive physical exercise causes oxidation of glutathione status in blood: Prevention by antioxidant administration. Am J Physiol 1992;263:R992-R995.
27. Thompson HJ: Effect of treadmill exercise intensity on hepatic glutathione content and its relevance to mammary tumorigenesis. J Sports Med Phys Fitness 1992;32:59-63.
28. Mcistcr A: Glutathione metabolism and its selective modification. J Biol Chem 1988;263:17205-17208.
29. Halliwcll B, Guttcridgc JMC: Free Radicals in Biology and Medicine. Oxford, Clarendon Press, 1985, pp 73-75,104-106.
30. Salmincn A, Vihko V: Lipid peroxidation in exercise myopathy. Exp Mol Pathol 1983;38:380-388.
31. Davis KJA, Quintanilha T, Brooks A, Packer L: Free radicals and tissue damage produced by exercise. Bio-chem Biophys Res Commun 1982; 107:1198-1205.
32. Dillard CJ, Litov RE, Savin WM, Dumelin EE, Tappel AA: Effects of exercise, vitamin E, and ozone on pulmonary function and lipid peroxidation. J Appl Physiol 1978:45: 927-932.
33. Jackson ML, Edwards RHT, Simons MCR: Electron spin resonance studies of intact mammalian skeletal muscle. Biochim Biophys Acta 1985:847:185-190.
34. Jenkins RR: Free radical chemistry: Relationship to exercise. Sports Med 1988;5:156-170.
35. Abe M, Reiter RJ, Orhii PB, Hara M, Poeggclcr B: inhibitory effect of melatonin on cataract formation in new bom rats: Evidence for an antioxidative role for melatonin. J Pineal Res 1994;17:94-100.
36. Reiter RJ, Mclchiorri D, Scwerynek E, Pocggcler B, Barlow-Waldcn LR, Chuang J, Ortiz GG, Acuna-Castro-viejo D: A review of the evidence supporting melatonin's role as an antioxidant. J Pineal Res 1995:18: 1-11.
37. Tan DX, Reiter RJ, Chen LD, Poeg-gelcr B, Manchester LC, Barlow-Waldcn LR: Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrolc. Carcinogenesis 1994;15:215-218.
38. Pierrefiche G, Topall G, Courboin G, Henriet I, Laborit H: Antioxidant activity of melatonin in mice. Res Commun Chern Pathol Pharmacol 1993;80:211-223.
39. English J, Bojkowski CJ, Poulton AL, Symons AM, Arendt J: Metabolism and pharmacokinetics of melatonin in the ewe. J Pineal Res 1987; 4:351-358.
40. Raynaud F, Mauviard F, GeofTriau M, Claustral B, Pevct P: Plasma 6-hydroxymclalonin, 6-sulfatoxyme-latonin and melatonin kinetics after melatonin administration to rats. Biol Signals 1993;2:358-366.
41. Ji LL, Fu R, Mitchell EW: Glutathione and antioxidant enzymes in skeletal muscle: Effects of fiber type and exercise intensity. J Appl Physiol 1992;73:1854-1859.
42. Sen CK, Marin E, Kretzschmar M, Hanninen O: Skeletal muscle and liver glutathione homeostasis in response to training, exercise, and immobilization. J Appl Physiol 1992; 73:1265-1272.
43. Barlow-Walden LR, Reiter RJ, Abe M, Pablos MI, Menendes-Pelaez A, Chen LD, Poeggcler B: Melatonin stimulates brain glutathione peroxidase activity. Neurochem Int 1995; 24:497-502.
44. Troiani ME, Reiter RJ, Tannen-baum MG, Puig-Domingo M, Guerrero JM, Menendes-Pelaez A: Neither the pituitary gland nor the sympathetic nervous system is responsible for eliciting the large drop in elevated rat pineal melatonin levels due to swimming. J Neural Transm 1988;74:149-160.
45. Troiani ME, Reiter RJ, Vaughan MK, Oaknin S, Vaughan GM: Swimming depresses nighttime melatonin content without changing N-acctyltransfcrase activity in the rat pineal gland. Neuroendocrinology 1988;47:55-60.
46. Ueck M, Troiani ME, Reiter RJ: Transient reduction in pineal melatonin levels but not N-acctyltrans-fcrasc activity in rats forced to swim for 15 minutes at night. Neurocndo-crinol Lett 1988;10:81-89.