Suppression of oxygen toxicity by melatonin

Acta Pharmacologica Sinica

Volumn 19, Issue 6, 1998, Pages 575-581

  Reiter, Russel J ^a   Tan, Dun Xian ^a   Qi, Wen Bo ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Aging; Antioxidants; Free radicals; Melatonin; Oxidative stress

Indexed keywords

ANTIOXIDANT; FREE RADICAL; GLUTATHIONE REDUCTASE; MELATONIN; NITRIC OXIDE SYNTHASE; SUPEROXIDE DISMUTASE;

AGING; ANTIOXIDANT ACTIVITY; CATALYSIS; DETOXIFICATION; DNA DAMAGE; ENZYME ACTIVITY; ENZYME RELEASE; OXIDATIVE STRESS; OXYGEN TOXICITY; PINEAL BODY; SHORT SURVEY;

ALZHEIMER DISEASE; ANIMALS; ANTIOXIDANTS; FREE RADICAL SCAVENGERS; HUMANS; MELATONIN;

EID: 0031743140     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (60)

1. Fridovich I. The biology of oxygen radicals. Science 1978; 201: 875-880.
2. Pryor WA, Squadrito GL. The chemistry of peroxynitrite, a product of the reaction of nitric oxide with superoxide. Am J Physiol 1995; 268: L699-L722.
3. Reiter RJ. Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr Rev 1991, 12: 151-180.
4. Reiter RJ, Melchiorri D, Sewerynek E, Poeggeler B, Barlow-Walden L, Chuang SH, et al. A review of the evidence supporting melatonin's role as an antioxidant. J Pineal Res 1995; 18: 1-11.
5. Costa EJ, Lopes RH, Lamy-Freund MT. Permeability of pure lipid bilayers to melatonin. J Pineal Res 1995; 18: 123-6.
6. Shida CS, Castrucci AML, Lamy-Freund MT. High melatonin solubility in aqueous medium. J Pineal Res 1994; 16: 198-201.
7. Ianas O, Olenescu R, Badescu I. Melatonin involvement in oxidative stress. Rom J Endocrinol 1991; 29: 147-53.
8. Tan DX, Chen LD, Poeggeler B, Manchester LC, Reiter RJ. Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocrine J 1993; 1: 57-60.
9. Matuszek Z, Reszka KJ, Chignell CF. Reaction of melatonin and related indoles with hydroxyl radical: EPR and spin trapping investigations. Free Radical Biol Med 1997; 23: 367-72.
10. Susa N, Ueno S, Furukawa Y, Ueda J, Sugiyama M. Potent protective effect of melatonin on chromium (VI)-induced DNA single strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes. Toxicol Appl Pharmacol 1997; 144: 377-84.
11. Stasica P, Ulanski P, Rosiak JM. Melatonin as a hydroxyl radical scavenger. J Pineal Res 1998; 25: 65-6.
12. Li XJ, Zhang LM, Gu J, Zhang AZ, Sun FY. Melatonin decreases production of hydroxyl radical during cerebral ischemia-reperfusion. Acta Pharmacol Sin 1997; 18: 394-96.
13. Pieri C, Marra M, Moroni F, Recchioni R, Marcheselli F. Melatonin: a peroxyl radical scavenger more effective than vitamin E. Life Sci 1994; 55: 271-6.
14. Marshall KA, Reiter RJ, Poeggeler B, Aruoma OI, Halliwell B. Evaluation of the antioxidant activity of melatonin in vitro. Free Radical Biol Med 1996; 21: 307-15.
15. Longoni B, Salgo MG, Pryor WA, Marchiafava PL. Effects of melatonin on lipid peroxidation induced by oxygen radicals. Life Sci 1998; 62: 853-9.
16. Reiter RJ. Antioxidant actions of melatonin. Adv Pharmacol 1997; 38: 103-17.
17. Cagnoli CM, Atabay C, Kharlamova E, Manev H. Melatonin protects neurons from singlet oxygen-induced apoptosis. J Pineal Res 1995; 18: 222-6.
18. Gilad E, Cuzzocrea S, Zingarelli B, Salzman AL, Szabo C. Melatonin is a scavenger of peroxynitrite anion. Life Sci 1997; 60: PL-169-74.
19. Cuzzocrea S, Zingarelli B, Costantino G, Caputi AP. Protective effect of melatonin in a non-septic shock model induced by zymosan in the rat. J Pineal Res 1998; 25: 24-33.
20. Noda Y, Mori A, Liburdy R, Packer L. Melatonin and its precursors exhibit nitric oxide scavenging activity. Pathophysiology 1998; 5 (Suppl 1): 85.
21. Guerrero JM, Reiter RJ, Ortiz GG, Pablos MI, Sewerynek E, Chuang JI. Melatonin prevents increases in neural nitric oxide and cyclic GMP production after transient brain ischemia and reperfusion in the Mongolian gerbil (Meriones unguiculatus). J Pineal Res 1997; 23:24-31.
22. Morrey KM, McLachlan JA, Serkin CD, Bakouche O. Activation of human monocytes by the pineal hormone melatonin. J Immunol 1994; 153: 2671-80.
23. Pieri C, Recchioni R, Moroni F, Marcheselli F, Marra M, Marinoni S, et al. Melatonin regulates the respiratory burst of human nutrophils and their depolarization. J Pineal Res 1998; 24: 43-9.
24. Hardeland R, Reiter RJ, Poeggeler B, Tan DX. The significance of the metabolism of the neurohormone melatonin: antioxidative protection and formation of bioactive substances. Neurosci Biobehav Rev 1993; 17: 347-57.
25. Roberts JE, Hu DN, Wishart JF. Pulse radiolysis studies of melatonin and chloromelatonin. J Photochem Photobiol 1998; 42: 125-32.
26. Kolter M, Rodriguez C, Sainz RM, Antolin I, Menendez-Pelaez A. Melatonin increases gene expression for antioxidant enzymes in rat brain cortex. J Pineal Res 1998; 24: 83-9.
27. Pablos MI, Reiter RJ, Ortiz GG, Guerrero JM, Agapito MT, Chuang JI, Sewerynek E. Rhythms of glutathione peroxidase and glutathione reductase in brain of chick and their inhibition by light. Neurochem Int 1998; 32: 69-75.
28. Sies H, Klotz LO, Sharov VS, Tanler R, Assmann A, Briviba K. Glutathione peroxidases as peroxynitrite reductases. Pathophysiology 1998; 5 (Suppl 1): 61.
29. Barlow-Walden LR, Reiter RJ, Abe M, Pablos M, Menendez-Pelaez A, Chen KD, et al. Melatonin stimulates brain glutathione peroxidase activity. Neurochem Int 1995; 26: 497-502.
30. Pozo D, Reiter RJ, Calvo JR, Guerrero JM. Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin. J Cell Biochem 1997; 65: 430-42.
31. Carlberg C, Weisenberg I. The orphan receptor family RZR/ROR, melatonin and 5-lipoxygenase: an unexpected relationship. J Pineal Res 1995; 18: 171-8.
32. Reiter RJ, Tan DX, Kim SJ, Qi W. Melatonin as a pharmacological agent against oxidative damage to lipids and DNA. Proc West Pharmacol Soc, in press.
33. Tan DX, Reiter RJ, Chen LD, Poeggeler B, Manchester LC, Barlow-Walden LR. Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. Carcinogenesis 1994; 15: 215-8.
34. Finocchiaro LM, Glikin GC. Intracellular melatonin distribution in cultured cell lines. J Pineal Res 1998; 24: 22-34.
35. Vijayalaxmi, Reiter RJ, Meltz M. Melatonin protects human blood lymphocytes from radiation-induced chromosome damage. Mutat Res 1995; 346: 23-31.
36. Vijayalaxmi, Reiter RJ, Herman TS, Meltz ML. Melatonin reduces gamma radiation-induced primary DNA damage in human blood lymphocytes. Mutat Res 1998; 397: 203-8.
37. Reiter RJ. Functional pleiotropy of the neurohormone melatonin: antioxidant protection and neuroendocrine regulation. Front Neuroendocrinol 1995; 16: 383-415.
38. Reiter RJ, Carneiro RC, Oh CS. Melatonin in relation to cellular antioxidative defense mechanisms. Horm Metab Res 1997; 29: 363-72.
39. Li ZR, Reiter RJ, Fujimori O, Oh CS, Duan YP. Cataractogenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: preventive actions of melatonin. J Pineal Res 1997; 22: 117-23.
40. Kelly MR, Loo G. Melatonin inhibits oxidative modification of human low-density lipoprotein. J Pineal Res 1997; 22: 203-9.
41. Prine FG, Juknat AA, Maxit AG, Cardalda C, Battle A. Melatonin's antioxidant protection against δ-aminolevulinic acid-induced oxidative damage in rat cerebellum. J Pineal Res 1997; 23: 40-6.
42. Pappolla MA, Sos M, Omar RA, Bick RJ, Hickson-Bick DLM, Reiter RJ, et al. Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. J Neurosci 1997; 17: 1683-90.
43. Mesenge C, Margaill I, Verrecchia C, Allix M, Boulu RG, Plokine M. Protective effect of melatonin in a model of traumatic brain injury in mice. J Pineal Res 1998; 25: 41-6.
44. Lezoualc'h F, Sparapani M, Behl C. N-acetyl-serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF-kappa B. J Pineal Res 1998; 24: 168-78.
45. Reiter RJ. Oxidative damage in the central nervous system: protection by melatonin. Prog Neurobiol 1998; 56: 359-69.
46. Abe M, Reiter RJ, Orhii PB, Hara M, Poeggeler B. Inhibitory effect of melatonin on cataract formation in newborn rats: evidence for an antioxidative role for melatonin. J Pineal Res 1994; 17: 94-100.
47. Limson J, Nyokong T, Daya S. The interaction of melatonin and its precursors with aluminum cadmium, copper, iron, lead and zinc: an adsorptive voltammetric study. J Pineal Res 1998;24: 15-21.
48. Garcia JJ, Reiter RJ, Guerrero JM, Escames G, Yu BP, Oh CS, et al. Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation. FEBS Lett 1997; 408: 297-300.
49. Garcia JJ, Reiter RJ, Ortiz GG, Oh CS, Tang L, Yu BP, Escames G. Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation. J Membr Biol 1998; 162: 59-65.
50. Reiter RJ, Richardson BA, Johnson LY, Ferguson BN, Dinh DT, Pineal melatonin rhythm: reduction in aging Syrian hamsters. Science 1980, 210: 1372-3.
51. Reiter RJ, Tan DX, Poeggeler B, Menendez-Pelaez B, Chen LD, Saarela S. Melatonin as a free radical scavenger: implications for aging and age-related diseases. Ann NY Acad Sci 1994; 719: 1-12.
52. Reiter RJ. Oxygen radical detoxification processes during aging: the functional importance of melatonin. Aging (Milana) 1995; 7: 340-51.
53. Reiter RJ. Aging and oxygen toxicity: relation to changes in melatonin. Age 1997; 20: 201-13.
54. Tan DX, Manchester LC, Reiter RJ, Qi W, Kim SJ, El-Sokkary G. (1998) Ischemia/reperfusion induced arhythmias in the isolated rat heart: prevention by melatonin. J Pineal Res 1998; 25: 184-91.
55. Reiter RJ, Pie J, Garcia JJ. Oxidative toxicity in models of neurodegeneration: responses to melatonin. Restr Neurol Neurosci 1998; 12: 135-42.
56. Reiter RJ. Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J 1995; 9: 526-33.
57. Uz T, Giusti P, Franceschini D, Kharlamov A, Manev H. Protective effect of melatonin against hippocampal DNA damage induced by intraperitoneal administration of kainate to rats. Neuroscience 1996; 73: 631-6.
58. Harman D. Free radical theory of aging. Mutat Res 1992; 275: 257-66.
59. Reiter RJ, Tang L, Garcia JJ, Muñoz-Hoyos A. Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci 1997; 60: 2255-71.
60. Brusco LI, Marquez M, Cardinali DP. Monozygotic twins with Alzheimer's disease treated with melatonin: a case report. J Pineal Res, in press.