Association study of MAO-A, COMT, 5-HT2A, DRD2, and DRD4 polymorphisms with illness time course in mood disorders

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 114, Issue 4, 2002, Pages 380-390

  Cusin, Cristina ^a   Serretti, Alessandro ^a   Lattuada, Enrico ^a   Lilli, Roberta ^a   Lorenzi, Cristina ^a   Smeraldi, Enrico ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

Bipolar disorder; Depressive disorder; Genetics; Longitudinal studies; Rapid cycling

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; CATECHOL METHYLTRANSFERASE; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; SEROTONIN 2A RECEPTOR;

ADULT; AFFECTIVE NEUROSIS; ARTICLE; CONTROLLED STUDY; DEPRESSION; DISEASE COURSE; DNA DETERMINATION; FEMALE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MANIC DEPRESSIVE PSYCHOSIS; MULTIVARIATE ANALYSIS OF VARIANCE; ONSET AGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; CATECHOL O-METHYLTRANSFERASE; FEMALE; HUMANS; MALE; MIDDLE AGED; MONOAMINE OXIDASE; MOOD DISORDERS; POLYMORPHISM, GENETIC; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; RECEPTORS, SEROTONIN;

GYMNOMYZA SAMOENSIS;

EID: 0037042096     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.10358     Document Type: Article

References (122)

1. Catechol O-methyltransferase pharmacogenetics: Photoaffinity labelling and Western blot analysis of human liver samples
2. Practice guideline for the treatment of patients with bipolar disorder
3. The family history method using diagnostic criteria: Reliability and validity
4. Course of affective disorders
5. The course of affective disorders
6. The depressive spectrum: Diagnostic classification and course
7. Association of dopamine D2 receptor molecular variant with schizophrenia
8. 5-HT2A receptor and bipolar affective disorder: Association studies in affected patients
9. Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants
10. Response to clozapine in acute mania is more rapid than that of chlorpromazine
11. Prediction of adolescent affective disorder: Effects of prior parental affective disorders and child psychopathology
12. The functional role of monoamine oxidases A and B in the mammalian central nervous system
13. Immunoaffinity purification and partial amino acid sequence analysis of catechol-O-methyltransferase from pig liver
14. The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain
15. Clozapine for treatment-refractory mania
16. Distribution of novel mutation in the first exon of the human dopamine D4 receptor gene in psychotic patients
17. Bipolar II illness: Course and outcome over a five-year period
18. Outcome of patients with chronic affective disorder: A five-year follow-up
19. No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms
20. Impact of clinical variables on illness time course in mood disorders
21. Influence of 5-HTTLPR and TPH variants on illness time course in mood disorders
22. Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder
23. Association between monoamine oxidase A activity in human male skin fibroblasts and genotype of the MAOA promoter-associated variable number tandem repeat
24. The role of dopamine in mood disorders
25. Saga of an adventure gene: Novelty seeking, substance abuse and the dopamine D4 receptor (D4DR) exon III repeat polymorphism
26. Personality and polymorphisms of genes involved in aminergic neurotransmission
27. A diagnostic interview: The schedule for affective disorders and schizophrenia
28. Meta-analysis of the association between the 7-repeat allele of the dopamine D(4) receptor-gene and attention deficit hyperactivity disorder
29. Conceptualization and rationale for consensus definitions of terms in major depressive disorder. Remission, recovery, relapse, and recurrence
30. Association of unipolar major depressive disorder with genes of the serotonergic and dopaminergic pathways
31. PI, GC, HP, and TF serum protein polymorphisms in Siena, Tuscany, Italy, with a review of data for Italy
32. Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promotor
33. Serotonin receptor subtypes
34. The human D2 dopamine receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP
35. Genetic variation of the 5-HT2A receptor gene and bipolar affective disorder
36. COMT and DRD3 polymorphisms, environmental exposures, and personality traits related to common mental disorders
37. A structural polymorphism of human dopamine D2 receptor, D2 (Ser311→Cys)
38. A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers
39. Dopamine D4 receptor 48-bp repeat polymorphism: No association with response to antipsychotic treatment, but association with catatonic schizophrenia
40. Serotonin-dopamine interaction and its relevance to schizophrenia
41. Possible association between monoamine oxidase A gene and bipolar affective disorder
42. Recovery in major depressive disorder: Analysis with the life table and regression models
43. Predictors of relapse in major depressive disorder
44. The longitudinal interval follow-up evaluation. A comprehensive method for assessing outcome in prospective longitudinal studies
45. Time to recovery, chronicity, and levels of psychopathology in major depression. A 5-year prospective follow-up of 431 subjects
46. Predictors of recurrence in affective disorder. A case register study
47. Recurrence in affective disorder. I. Case register study
48. The long-term outcome of depressive illness
49. Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder
50. Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5
51. How do risk factors work together? Mediators, moderators, and independent, overlapping, and proxy risk factors
52. The effects of a selective D4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia
53. No evidence for an association of affective disorders with high- or low-activity allele of catecholo-methyltransferase gene
54. A functional polymorphism in the promoter region of monoamine oxidase-A gene and mood disorders
55. Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome
56. Human catechol-O-methyltransferase pharmacogenetics: Description of a functional polymorphism and its potential application to neuropsychiatric disorders
57. Lack of association of catechol-O-methyltransferase (COMT) functional polymorphism in bipolar affective disorder
58. A rapid non-enzimatic method for the preparation of HMW DNA from blood for RFLP studies
59. Best estimate of lifetime psychiatric diagnosis: A methodological study
60. Catechol-O-methyltransferase Val158Met polymorphism: Frequency analysis in Han Chinese subjects and allelic association of the low activity allele with bipolar affective disorder
61. No evidence of association between dopamine D4 receptor variants and bipolar affective disorder
62. Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder
63. Association analysis between mood disorder and monoamine oxidase gene
64. Kinetics of human soluble and membrane-bound catechol-O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme
65. Cloning and characterization of human placental catechol-O-methyltransferase cDNA
66. Analysis of the D4 dopamine receptor gene variant in an Italian schizophrenia kindred
67. The serotonin hypothesis of major depression
68. No association between bipolar affective disorder and a serotonin receptor (5-HT2A) polymorphism
69. Dopamine D2, D3 and D4 receptor and transporter gene polymorphisms and mood disorders
70. A European multicenter association study of HTR2A receptor polymorphism in bipolar affective disorder
71. A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system
72. Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist
73. Heterogeneity of depression. Classification of depressive subtypes by longitudinal course
74. Preliminary evidence of an association between bipolar disorder in females and the catechol-O-methyltransferase gene
75. Linkage studies between affective disorder and dopamine D2, D3, and D4 receptor gene loci in four Japanese pedigrees
76. Increased prevalence and earlier onset of mood disorders among relatives of prepubertal versus adult probands
77. Dopamine D2 receptor molecular variant and schizophrenia
78. Association analysis of the monoamine oxidase A gene in bipolar affective disorder by using family-based internal controls
79. A family study of rapid-cycling bipolar illness
80. The dopamine D(4) receptor: One decade of research
81. Low activity allele of catechol-O-methyltransferase gene and Japanese unipolar depression
82. Association study between bipolar disorder and candidate genes involved in dopamine-serotonin metabolism and GABAergic neurotransmission: A preliminary report
83. Ultra-ultra rapid cycling bipolar disorder is associated with the low activity catecholamine-O-methyltransferase allele
84. Genetic association between monoamine oxidase and manic-depressive illness: Comparison of relative risk and haplotype relative risk data
85. A weak association between TH and DRD2 genes and bipolar affective disorder in a Spanish sample
86. Association between bipolar disorder and monoamine oxidase A gene polymorphisms: Results of a multicenter study
87. Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: Analysis and meta-analysis
88. A functional polymorphism in the monoamine oxidase A gene promoter
89. The monoamine oxidase-A gene and major psychosis in Japanese subjects
90. Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder
91. Dopamine receptor D4 gene is associated with delusional symptomatology in mood disorders
92. Dopamine receptor D2 ser cys311 variant associated with disorganized symptomatology of schizophrenia
93. No association between serotonin-2a receptor gene polymorphism and psychotic symptomatology of mood disorders
94. Genetic variants of dopamine receptor D4 and psychopathology
95. Dopamine receptor D2 ser/cys 311 variant is associated with delusion and disorganization symptomatology in major psychoses
96. Further evidence supporting the association between the dopamine receptor D2 ser/cys311 variant and disorganized symptomatology of schizophrenia
97. Serotonin receptor 2A, 2C, 1A genes and response to lithium prophylaxis in mood disorders
98. DRD4 exon 3 variants associated with delusional symptomatology in major psychoses: A study on 2,011 affected subjects
99. Electroconvulsive therapy and resistant depression: Clinical implications of seizure threshold
100. Association study of bipolar disorder with candidate genes involved in catecholamine neurotransmission: DRD2, DRD3, DAT1, and TH genes
101. Analysis of a functional catechol-O-methyltransferase gene polymorphism in schizophrenia: Evidence for association with aggressive and antisocial behavior
102. Association analysis of the functional monoamine oxidase A gene promoter polymorphism in psychiatric disorders
103. PNU-96415E, a potential antipsychotic agent with clozapine-like pharmacological properties
104. Dopamine D-4 receptors: Significance for molecular psychiatry at the millennium
105. Genomic organization of the human catechol-O-methyltransferase gene and its expression from two distinct promoters
106. Genetic basis of attention deficit and hyperactivity
107. MAOA: Association and linkage studies with lithium responsive bipolar disorder
108. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine
109. Multiple dopamine D4 receptor variants in the human population
110. Clinical symptoms and platelet monoamine oxidase in subgroups and different states of affective disorders
111. Association between different psychotic disorders and the DRD4 polymorphism, but no differences in the main ligand binding region of the DRD4 receptor protein compared to controls
112. Dopaminergic mechanisms in depression and mania
113. Further distinctions between manic-depressive illness (bipolar disorder) and primary depressive disorder (unipolar depression)
114. A prospective follow-up of patients with bipolar and primary unipolar affective disorder
115. A family study of manic-depressive (bipolar I) disease. Is it a distinct illness separable from primary unipolar depression?
116. Polymorphisms in dopamine receptors: What do they tell us?
117. Is clozapine a mood stabilizer?
118. Serotonin2A receptor gene polymorphism in mood disorders