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Volumn 23, Issue 12, 2002, Pages 1093-1101

Immunomodulatory effects and mechanisms of plant alkaloid tetrandrine in autoimmune diseases

Author keywords

Alkaloids; Autoimmune diseases; T lymphocytes; Tetrandrine

Indexed keywords

ANTIMALARIAL AGENT; ANTIOXIDANT; ANTIRHEUMATIC AGENT; ASCORBIC ACID; AZATHIOPRINE; BERBAMINE; BISBENZYLISOQUINOLINE ALKALOID; CHINESE DRUG; CORTICOSTEROID; CYCLOSPORIN; DAURICINE; FANGQUINOLINE; GLUCOCORTICOID; GLUTATHIONE; GOLD SALT; HERBACEOUS AGENT; HYDROCORTISONE; HYDROXYCHLOROQUINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; ISOTETRANDRINE; LEFLUNOMIDE; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN KINASE C; SALAZOSULFAPYRIDINE; TACROLIMUS; TETRANDRINE; UNINDEXED DRUG;

EID: 0036901923     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (80)

References (83)
  • 1
    • 9244247260 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications
    • O'Dell JR, Haire CE, Erikson N, Drymalski W, Palmer W, Eckhoff PJ, et al. Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications [see comments]. N Engl J Med 1996; 334: 1287-91.
    • (1996) N Engl J Med , vol.334 , pp. 1287-1291
    • O'Dell, J.R.1    Haire, C.E.2    Erikson, N.3    Drymalski, W.4    Palmer, W.5    Eckhoff, P.J.6
  • 2
    • 0033535754 scopus 로고    scopus 로고
    • Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: A randomised trial
    • FIN-RACo trial group
    • Mottonen T, Hannonen P, Leirisalo-Repo M, Nissila M, Kautiainen H, Korpela M, et al. Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: A randomised trial. FIN-RACo trial group. Lancet 1999; 353: 1568-73.
    • (1999) Lancet , vol.353 , pp. 1568-1573
    • Mottonen, T.1    Hannonen, P.2    Leirisalo-Repo, M.3    Nissila, M.4    Kautiainen, H.5    Korpela, M.6
  • 3
    • 0036166382 scopus 로고    scopus 로고
    • COBRA combination therapy in patients with early rheumatoid arthritis: Long-term structural benefits of a brief intervention
    • Landewe RB, Boers M, Verhoeven AC, Westhovens R, van de Laar MA, Markusse HM, et al. COBRA combination therapy in patients with early rheumatoid arthritis: Long-term structural benefits of a brief intervention. Arthritis Rheum 2002; 46: 347-56.
    • (2002) Arthritis Rheum , vol.46 , pp. 347-356
    • Landewe, R.B.1    Boers, M.2    Verhoeven, A.C.3    Westhovens, R.4    Van de Laar, M.A.5    Markusse, H.M.6
  • 4
    • 0030970556 scopus 로고    scopus 로고
    • The role of T cells in the immunopathogenesis of rheumatoid arthritis: New perspectives
    • Fox DA. The role of T cells in the immunopathogenesis of rheumatoid arthritis: New perspectives. Arthritis Rheum 1997; 40: 598-609.
    • (1997) Arthritis Rheum , vol.40 , pp. 598-609
    • Fox, D.A.1
  • 5
    • 0034044349 scopus 로고    scopus 로고
    • New insights into the pathogenesis of rheumatoid arthritis
    • Weyand CM. New insights into the pathogenesis of rheumatoid arthritis. Rheumatology 2000; 39: 3-8.
    • (2000) Rheumatology , vol.39 , pp. 3-8
    • Weyand, C.M.1
  • 6
    • 0035207357 scopus 로고    scopus 로고
    • The autoimmune pathogenesis of rheumatoid arthritis: Role of autoreactive T cells and new immunotherapies
    • VanderBorght A, Geusens P, Raus J, Stinissen P. The autoimmune pathogenesis of rheumatoid arthritis: Role of autoreactive T cells and new immunotherapies. Semin Arthritis Rheum 2001; 31: 160-75.
    • (2001) Semin Arthritis Rheum , vol.31 , pp. 160-175
    • VanderBorght, A.1    Geusens, P.2    Raus, J.3    Stinissen, P.4
  • 7
    • 0035010959 scopus 로고    scopus 로고
    • Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts
    • Panayi GS, Corrigall VM, Pitzalis C. Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts. Rheum Dis Clin North Am 2001; 27: 317-34.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 317-334
    • Panayi, G.S.1    Corrigall, V.M.2    Pitzalis, C.3
  • 8
    • 0027403299 scopus 로고
    • The role of the CD28 receptor during T cell responses to antigen
    • Linsley PS, Ledbetter JA. The role of the CD28 receptor during T cell responses to antigen. Annu Rev Immunol 1993; 11: 191-212.
    • (1993) Annu Rev Immunol , vol.11 , pp. 191-212
    • Linsley, P.S.1    Ledbetter, J.A.2
  • 10
    • 0027451433 scopus 로고
    • B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance
    • Boussiotis VA, Freeman GJ, Gray G, Gribben J, Nadler LM. B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance. J Exp Med 1993; 178: 1753-63.
    • (1993) J Exp Med , vol.178 , pp. 1753-1763
    • Boussiotis, V.A.1    Freeman, G.J.2    Gray, G.3    Gribben, J.4    Nadler, L.M.5
  • 11
    • 0028483990 scopus 로고
    • Treatment of murine lupus with CTLA4Ig
    • Finck BK, Linsley PS, Wofsy D. Treatment of murine lupus with CTLA4Ig. Science 1994; 265: 1225-7.
    • (1994) Science , vol.265 , pp. 1225-1227
    • Finck, B.K.1    Linsley, P.S.2    Wofsy, D.3
  • 12
  • 13
    • 0027451441 scopus 로고
    • Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion
    • Lin H, Bolling SF, Linsley PS, Wei RQ, Gordon D, Thompson CB, et al. Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. J Exp Med 1993; 178: 1801-6.
    • (1993) J Exp Med , vol.178 , pp. 1801-1806
    • Lin, H.1    Bolling, S.F.2    Linsley, P.S.3    Wei, R.Q.4    Gordon, D.5    Thompson, C.B.6
  • 14
    • 0029864501 scopus 로고    scopus 로고
    • Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection
    • Azuma H, Chandraker A, Nadeau K, Hancock WW, Carpenter CB, Tilney NL, et al. Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection [see comments]. Proc Natl Acad Sci USA 1996; 93: 12439-44.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12439-12444
    • Azuma, H.1    Chandraker, A.2    Nadeau, K.3    Hancock, W.W.4    Carpenter, C.B.5    Tilney, N.L.6
  • 15
    • 0032103321 scopus 로고    scopus 로고
    • Late blockade of T cell costimulation interrupts progression of experimental chronic allograft rejection
    • Chandraker A, Azuma H, Nadeau K, Carpenter CB, Tilney NL, Hancock WW, et al. Late blockade of T cell costimulation interrupts progression of experimental chronic allograft rejection. J Clin Invest 1998; 101: 2309-18.
    • (1998) J Clin Invest , vol.101 , pp. 2309-2318
    • Chandraker, A.1    Azuma, H.2    Nadeau, K.3    Carpenter, C.B.4    Tilney, N.L.5    Hancock, W.W.6
  • 16
    • 0030293633 scopus 로고    scopus 로고
    • Differential effect of CTLA4Ig on murine graft-versus-host disease (GVHD) development: CTLA4Ig prevents both acute and chronic GVHD development but reverses only chronic GVHD
    • Via CS, Rus V, Nguyen P, Linsley P, Gause WC. Differential effect of CTLA4Ig on murine graft-versus-host disease (GVHD) development: CTLA4Ig prevents both acute and chronic GVHD development but reverses only chronic GVHD. J Immunol 1996; 157: 4258-67.
    • (1996) J Immunol , vol.157 , pp. 4258-4267
    • Via, C.S.1    Rus, V.2    Nguyen, P.3    Linsley, P.4    Gause, W.C.5
  • 17
    • 8944232102 scopus 로고    scopus 로고
    • Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation
    • Levine BL, Mosca JD, Riley JL, Carroll RG, Vahey MT, Jagodzinski LL, et al. Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation. Science 1996; 272: 1939-43.
    • (1996) Science , vol.272 , pp. 1939-1943
    • Levine, B.L.1    Mosca, J.D.2    Riley, J.L.3    Carroll, R.G.4    Vahey, M.T.5    Jagodzinski, L.L.6
  • 18
    • 0034605033 scopus 로고    scopus 로고
    • Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells
    • Abrams JR, Kelley SL, Hayes E, Kikuchi T, Brown MJ, Kang S, et al. Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells. J Exp Med 2000; 192: 681-94.
    • (2000) J Exp Med , vol.192 , pp. 681-694
    • Abrams, J.R.1    Kelley, S.L.2    Hayes, E.3    Kikuchi, T.4    Brown, M.J.5    Kang, S.6
  • 19
    • 0035478298 scopus 로고    scopus 로고
    • Local costimulation reinvigorates tumor-specific cytolytic T lymphocytes for experimental therapy in mice with large tumor burdens
    • Bai XF, Bender J, Liu J, Zhang H, Wang Y, Li O, et al. Local costimulation reinvigorates tumor-specific cytolytic T lymphocytes for experimental therapy in mice with large tumor burdens. J Immunol 2001; 167: 3936-43.
    • (2001) J Immunol , vol.167 , pp. 3936-3943
    • Bai, X.F.1    Bender, J.2    Liu, J.3    Zhang, H.4    Wang, Y.5    Li, O.6
  • 21
    • 0032715757 scopus 로고    scopus 로고
    • Differential loss of T cell signaling molecules in metastatic melanoma patients' T lymphocyte subsets expressing distinct TCR variable regions
    • Maccalli C, Pisarra P, Vegetti C, Sensi M, Parmiani G, Anichini A. Differential loss of T cell signaling molecules in metastatic melanoma patients' T lymphocyte subsets expressing distinct TCR variable regions. J Immunol 1999; 163: 6912-23.
    • (1999) J Immunol , vol.163 , pp. 6912-6923
    • Maccalli, C.1    Pisarra, P.2    Vegetti, C.3    Sensi, M.4    Parmiani, G.5    Anichini, A.6
  • 23
    • 0032528419 scopus 로고    scopus 로고
    • Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28-T cells from rheumatoid arthritis patients
    • Schirmer M, Vallejo AN, Weyand CM, Goronzy JJ. Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28-T cells from rheumatoid arthritis patients. J Immunol 1998; 161: 1018-25.
    • (1998) J Immunol , vol.161 , pp. 1018-1025
    • Schirmer, M.1    Vallejo, A.N.2    Weyand, C.M.3    Goronzy, J.J.4
  • 24
    • 0031982940 scopus 로고    scopus 로고
    • Apoptosis in rheumatoid arthritis: A novel pathway in the regulation of synovial tissue
    • Nishioka K, Hasunuma T, Kato T, Sumida T, Kobata T. Apoptosis in rheumatoid arthritis: A novel pathway in the regulation of synovial tissue. Arthritis Rheum 1998; 41: 1-9.
    • (1998) Arthritis Rheum , vol.41 , pp. 1-9
    • Nishioka, K.1    Hasunuma, T.2    Kato, T.3    Sumida, T.4    Kobata, T.5
  • 25
    • 0035318470 scopus 로고    scopus 로고
    • Apoptosis in autoimmune diseases
    • Eguchi K. Apoptosis in autoimmune diseases. Internal Med 2001; 40: 275-84.
    • (2001) Internal Med , vol.40 , pp. 275-284
    • Eguchi, K.1
  • 26
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S. Apoptosis by death factor. Cell 1997; 88: 355-65.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 27
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson MD, Weil M, Raff MC. Programmed cell death in animal development. Cell 1997; 88: 347-54.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 28
    • 0030891492 scopus 로고    scopus 로고
    • Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus
    • Utz PJ, Hottelet M, Schur PH, Anderson P. Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus. J Exp Med 1997; 185: 843-54.
    • (1997) J Exp Med , vol.185 , pp. 843-854
    • Utz, P.J.1    Hottelet, M.2    Schur, P.H.3    Anderson, P.4
  • 29
    • 0032917731 scopus 로고    scopus 로고
    • Autoantigens as substrates for apoptotic proteases: Implications for the pathogenesis of systemic autoimmune disease
    • Rosen A, Casciola-Rosen L. Autoantigens as substrates for apoptotic proteases: Implications for the pathogenesis of systemic autoimmune disease. Cell Death Differ 1999; 6: 6-12.
    • (1999) Cell Death Differ , vol.6 , pp. 6-12
    • Rosen, A.1    Casciola-Rosen, L.2
  • 30
    • 0032914025 scopus 로고    scopus 로고
    • The role of apoptosis in autoimmunity: Immunogen, antigen, and accelerant: Genetically determined failure of activation-induced apoptosis of autoreactive T cells as a cause of multiple sclerosis
    • Levine JS, Koh JS, Pender MP. The role of apoptosis in autoimmunity: Immunogen, antigen, and accelerant: Genetically determined failure of activation-induced apoptosis of autoreactive T cells as a cause of multiple sclerosis. Semin Nephrol 1999; 19: 34-47.
    • (1999) Semin Nephrol , vol.19 , pp. 34-47
    • Levine, J.S.1    Koh, J.S.2    Pender, M.P.3
  • 31
    • 0033875820 scopus 로고    scopus 로고
    • Remnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity
    • Rovere P, Sabbadini MG, Fazzini F, Bondanza A, Zimmermann VS, Rugarli C, et al. Remnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity. Arthritis Rheum 2000; 43: 1663-72.
    • (2000) Arthritis Rheum , vol.43 , pp. 1663-1672
    • Rovere, P.1    Sabbadini, M.G.2    Fazzini, F.3    Bondanza, A.4    Zimmermann, V.S.5    Rugarli, C.6
  • 32
    • 0032528419 scopus 로고    scopus 로고
    • Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28-T cells from rheumatoid arthritis patients
    • Schirmer M, Vallejo AN, Weyand CM, Goronzy JJ. Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28-T cells from rheumatoid arthritis patients. J Immunol 1998; 161: 1018-25.
    • (1998) J Immunol , vol.161 , pp. 1018-1025
    • Schirmer, M.1    Vallejo, A.N.2    Weyand, C.M.3    Goronzy, J.J.4
  • 33
    • 0028938366 scopus 로고
    • The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity
    • Nakajima H, Golstein P, Henkart PA. The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity. J Exp Med 1995; 181: 1905-9.
    • (1995) J Exp Med , vol.181 , pp. 1905-1909
    • Nakajima, H.1    Golstein, P.2    Henkart, P.A.3
  • 34
    • 0028036918 scopus 로고
    • Autoimmune disease. A problem of defective apoptosis
    • Mountz JD, Wu J, Cheng J, Zhou T. Autoimmune disease. A problem of defective apoptosis. Arthritis Rheum 1994; 37: 1415-20.
    • (1994) Arthritis Rheum , vol.37 , pp. 1415-1420
    • Mountz, J.D.1    Wu, J.2    Cheng, J.3    Zhou, T.4
  • 36
    • 0032495663 scopus 로고    scopus 로고
    • Genetically determined failure of activationinduced apoptosis of autoreactive T cells as a cause of multiple sclerosis
    • Pender MP. Genetically determined failure of activationinduced apoptosis of autoreactive T cells as a cause of multiple sclerosis. Lancet 1998; 351: 978-81.
    • (1998) Lancet , vol.351 , pp. 978-981
    • Pender, M.P.1
  • 37
    • 0344404151 scopus 로고    scopus 로고
    • Systemic autoimmune disease as a consequence of defective lymphocyte death
    • Hunig T, Schimpl A. Systemic autoimmune disease as a consequence of defective lymphocyte death. Curr Opin Immunol 1997; 9: 826-30.
    • (1997) Curr Opin Immunol , vol.9 , pp. 826-830
    • Hunig, T.1    Schimpl, A.2
  • 38
    • 0032942973 scopus 로고    scopus 로고
    • Apoptosis in the effector phase of autoimmune diabetes, multiple sclerosis and thyroiditis
    • Ohsako S, Elkon KB. Apoptosis in the effector phase of autoimmune diabetes, multiple sclerosis and thyroiditis. Cell Death Differ 1999; 6: 13-21.
    • (1999) Cell Death Differ , vol.6 , pp. 13-21
    • Ohsako, S.1    Elkon, K.B.2
  • 39
    • 0032573853 scopus 로고    scopus 로고
    • To die or not to die: An overview of apoptosis and its role in disease
    • Hetts SW. To die or not to die: An overview of apoptosis and its role in disease. JAMA 1998; 279: 300-7.
    • (1998) JAMA , vol.279 , pp. 300-307
    • Hetts, S.W.1
  • 40
    • 0032838994 scopus 로고    scopus 로고
    • T cells: Pathogenic cells and therapeutic targets in rheumatoid arthritis
    • Yocum DE. T cells: Pathogenic cells and therapeutic targets in rheumatoid arthritis. Semin Arthritis Rheum 1999; 29: 27-35.
    • (1999) Semin Arthritis Rheum , vol.29 , pp. 27-35
    • Yocum, D.E.1
  • 41
    • 0012096367 scopus 로고
    • Pharmacognostic and chemical identification of Fang Ji (Stephania tetrandra)
    • Feng YX, Chen H. Pharmacognostic and chemical identification of Fang Ji (Stephania tetrandra). Chin J Pharm Anal 1985; 5: 28-31.
    • (1985) Chin J Pharm Anal , vol.5 , pp. 28-31
    • Feng, Y.X.1    Chen, H.2
  • 43
    • 0024453099 scopus 로고
    • Effect of tetrandrine on immunological responses and cardiac transplant rejection in mice
    • Li SY, Teh BS, Seow WK, Ling LH, Thong YH. Effect of tetrandrine on immunological responses and cardiac transplant rejection in mice. Int Arch Allergy Appl Immunol 1989; 90: 169-73.
    • (1989) Int Arch Allergy Appl Immunol , vol.90 , pp. 169-173
    • Li, S.Y.1    Teh, B.S.2    Seow, W.K.3    Ling, L.H.4    Thong, Y.H.5
  • 44
    • 0026670777 scopus 로고
    • Selective inhibition of T-cell-dependent immune responses by bisbenzylisoquinoline alkaloids in vivo
    • Kondo Y, Imai Y, Hojo H, Hashimoto Y, Nozoe S. Selective inhibition of T-cell-dependent immune responses by bisbenzylisoquinoline alkaloids in vivo. Int J Immunopharmacol 1992; 14: 1181-6.
    • (1992) Int J Immunopharmacol , vol.14 , pp. 1181-1186
    • Kondo, Y.1    Imai, Y.2    Hojo, H.3    Hashimoto, Y.4    Nozoe, S.5
  • 45
    • 0028171220 scopus 로고
    • Anti-inflammatory activity of the isoquinoline alkaloid, tetrandrine, against established adjuvant arthritis in rats
    • Whitehouse MW, Fairlie DP, Thong YH. Anti-inflammatory activity of the isoquinoline alkaloid, tetrandrine, against established adjuvant arthritis in rats. Agents Actions 1994; 42: 123-7.
    • (1994) Agents Actions , vol.42 , pp. 123-127
    • Whitehouse, M.W.1    Fairlie, D.P.2    Thong, Y.H.3
  • 46
    • 0033571497 scopus 로고    scopus 로고
    • Plant alkaloid tetrandrine and its analog block CD28-costimulated activities of human peripheral blood T cells: Potential immunosuppressants in transplantation immunology
    • Lai JH, Ho LJ, Kwan CY, Chang DM, Lee TC. Plant alkaloid tetrandrine and its analog block CD28-costimulated activities of human peripheral blood T cells: Potential immunosuppressants in transplantation immunology. Transplantation 1999; 68: 1383-92.
    • (1999) Transplantation , vol.68 , pp. 1383-1392
    • Lai, J.H.1    Ho, L.J.2    Kwan, C.Y.3    Chang, D.M.4    Lee, T.C.5
  • 47
    • 0033041740 scopus 로고    scopus 로고
    • Plant alkaloid tetrandrine downregulates protein kinase C-dependent signaling pathway in T cells
    • Ho LJ, Chang DM, Lee TC, Chang ML, Lai JH. Plant alkaloid tetrandrine downregulates protein kinase C-dependent signaling pathway in T cells. Eur J Pharmacol 1999; 367: 389-98.
    • (1999) Eur J Pharmacol , vol.367 , pp. 389-398
    • Ho, L.J.1    Chang, D.M.2    Lee, T.C.3    Chang, M.L.4    Lai, J.H.5
  • 48
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function, and regulation
    • Newton AC. Protein kinase C: Structure, function, and regulation. J Biol Chem 1995; 270: 28495-8.
    • (1995) J Biol Chem , vol.270 , pp. 28495-28498
    • Newton, A.C.1
  • 49
    • 0030762437 scopus 로고    scopus 로고
    • The potential for isoenzyme-selective modulation of protein kinase C
    • Hofmann J. The potential for isoenzyme-selective modulation of protein kinase C. FASEB J 1997; 11: 649-69.
    • (1997) FASEB J , vol.11 , pp. 649-669
    • Hofmann, J.1
  • 50
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilincyclosporin A and FKBP-FK506 complexes
    • Liu J, Farmer JD, Lane WS Jr, Friedman J, Weissman I, Schreiber SL. Calcineurin is a common target of cyclophilincyclosporin A and FKBP-FK506 complexes. Cell 1991; 66: 807-15.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane W.S., Jr.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 51
    • 0027491811 scopus 로고
    • Synergy between tetrandrine and FK506 in prevention of diabetes in BB rats
    • Lieberman I, Heil BV, Seow WK, Thong YH. Synergy between tetrandrine and FK506 in prevention of diabetes in BB rats. Life Sci 1993; 53: PLA53-8.
    • (1993) Life Sci , vol.53
    • Lieberman, I.1    Heil, B.V.2    Seow, W.K.3    Thong, Y.H.4
  • 52
    • 0025261308 scopus 로고
    • Tetrandrine, a plant alkaloid, inhibits the production of tumour necrosis factor-alpha (cachectin) hy human monocytes
    • Ferrante A, Seow WK, Rowan-Kelly B, Thong YH. Tetrandrine, a plant alkaloid, inhibits the production of tumour necrosis factor-alpha (cachectin) hy human monocytes. Clin Exp Immunol 1990; 80: 232-5.
    • (1990) Clin Exp Immunol , vol.80 , pp. 232-235
    • Ferrante, A.1    Seow, W.K.2    Rowan-Kelly, B.3    Thong, Y.H.4
  • 53
    • 0028810276 scopus 로고
    • Inhibitory effects of bisbenzylisoquinoline alkaloids on induction of proinflammatory cytokines, interleukin-1 and tumor necrosis factor-alpha
    • Onai N, Tsunokawa Y, Suda M, Watanabe N, Nakamura K, Sugimoto Y, et al. Inhibitory effects of bisbenzylisoquinoline alkaloids on induction of proinflammatory cytokines, interleukin-1 and tumor necrosis factor-alpha. Planta Med 1995; 61: 497-501.
    • (1995) Planta Med , vol.61 , pp. 497-501
    • Onai, N.1    Tsunokawa, Y.2    Suda, M.3    Watanabe, N.4    Nakamura, K.5    Sugimoto, Y.6
  • 54
    • 0030898022 scopus 로고    scopus 로고
    • The effects of traditional antirheumatic herbal medicines on immune response cells
    • Chang DM, Chang WY, Kuo SY, Chang ML. The effects of traditional antirheumatic herbal medicines on immune response cells. J Rheumatol 1997; 24: 436-41.
    • (1997) J Rheumatol , vol.24 , pp. 436-441
    • Chang, D.M.1    Chang, W.Y.2    Kuo, S.Y.3    Chang, M.L.4
  • 55
    • 0029812787 scopus 로고    scopus 로고
    • Tetrandrine inhibits breakdown of bloodaqueous barrier induced by endotoxin and interleukin-1 alpha in rats
    • Xiao JG, Chiou GC. Tetrandrine inhibits breakdown of bloodaqueous barrier induced by endotoxin and interleukin-1 alpha in rats. J Ocular Pharmacol Ther 1996; 12: 323-9.
    • (1996) J Ocular Pharmacol Ther , vol.12 , pp. 323-329
    • Xiao, J.G.1    Chiou, G.C.2
  • 56
    • 0027485757 scopus 로고
    • Inhibitory effect of bisbenzylisoquinoline alkaloids on nitric oxide production in activated macrophages
    • Kondo Y, Takano F, Hojo H. Inhibitory effect of bisbenzylisoquinoline alkaloids on nitric oxide production in activated macrophages. Biochem Pharmacol 1993; 46: 1887-92.
    • (1993) Biochem Pharmacol , vol.46 , pp. 1887-1892
    • Kondo, Y.1    Takano, F.2    Hojo, H.3
  • 57
    • 0026898085 scopus 로고
    • Tetrandrine on monocyte migration induced by endothelial cell-derived chemotactic factor
    • Zhou X. Tetrandrine on monocyte migration induced by endothelial cell-derived chemotactic factor. Chin Med J 1992; 72: 424-6.
    • (1992) Chin Med J , vol.72 , pp. 424-426
    • Zhou, X.1
  • 58
    • 0031977898 scopus 로고    scopus 로고
    • Inhibitory effects of tetrandrine on angiogenesis in adjuvant-induced chronic inflammation and tube formation of vascular endothelial cells
    • Kobayashi S, Inaba K, Kimura I, Kimura M. Inhibitory effects of tetrandrine on angiogenesis in adjuvant-induced chronic inflammation and tube formation of vascular endothelial cells. Biol Pharm Bull 1998; 21: 346-9.
    • (1998) Biol Pharm Bull , vol.21 , pp. 346-349
    • Kobayashi, S.1    Inaba, K.2    Kimura, I.3    Kimura, M.4
  • 59
    • 0022535575 scopus 로고
    • Inhibitory effects of tetrandrine on human neutrophil and monocyte adherence
    • Seow WK, Li SY, Thong YH. Inhibitory effects of tetrandrine on human neutrophil and monocyte adherence. Immunol Lett 1986; 13: 83-8.
    • (1986) Immunol Lett , vol.13 , pp. 83-88
    • Seow, W.K.1    Li, S.Y.2    Thong, Y.H.3
  • 60
    • 0032705352 scopus 로고    scopus 로고
    • Tetrandrine ameliorates ischaemia-reperfusion injury of rat myocardium through inhibition of neutrophil priming and activation
    • Shen YC, Chen CF, Sung YJ. Tetrandrine ameliorates ischaemia-reperfusion injury of rat myocardium through inhibition of neutrophil priming and activation. Br J Pharmacol 1999; 128: 1593-601.
    • (1999) Br J Pharmacol , vol.128 , pp. 1593-1601
    • Shen, Y.C.1    Chen, C.F.2    Sung, Y.J.3
  • 61
    • 0021367846 scopus 로고
    • Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
    • Cohen JJ, Duke RC. Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol 1984; 132: 38-42.
    • (1984) J Immunol , vol.132 , pp. 38-42
    • Cohen, J.J.1    Duke, R.C.2
  • 62
    • 1842289274 scopus 로고    scopus 로고
    • Induction of apoptosis in peripheral blood lymphocytes following treatment in vitro with hydroxychloroquine
    • Meng XW, Feller JM, Ziegler JB, Pittman SM, Ireland CM. Induction of apoptosis in peripheral blood lymphocytes following treatment in vitro with hydroxychloroquine. Arthritis Rheum 1997; 40: 927-35.
    • (1997) Arthritis Rheum , vol.40 , pp. 927-935
    • Meng, X.W.1    Feller, J.M.2    Ziegler, J.B.3    Pittman, S.M.4    Ireland, C.M.5
  • 63
    • 0029117289 scopus 로고
    • Nonsteroidal anti-inflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts
    • Lu X, Xie W, Reed D, Bradshaw WS, Simmons DL. Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts. Proc Natl Acad Sci USA 1995; 92: 7961-5.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7961-7965
    • Lu, X.1    Xie, W.2    Reed, D.3    Bradshaw, W.S.4    Simmons, D.L.5
  • 64
    • 0032891801 scopus 로고    scopus 로고
    • Mechanism of immunosuppression of the antirheumatic herb TWHf in human T cells
    • Ho LJ, Chang DM, Chang ML, Kuo SY, Lai JH. Mechanism of immunosuppression of the antirheumatic herb TWHf in human T cells. J Rheumatol 1999; 26: 14-24.
    • (1999) J Rheumatol , vol.26 , pp. 14-24
    • Ho, L.J.1    Chang, D.M.2    Chang, M.L.3    Kuo, S.Y.4    Lai, J.H.5
  • 65
    • 0030909069 scopus 로고    scopus 로고
    • Cytotoxicity to macrophages of tetrandrine, an antisilicosis alkaloid, accompanied by an overproduction of prostaglandins
    • Pang L, Hoult JR. Cytotoxicity to macrophages of tetrandrine, an antisilicosis alkaloid, accompanied by an overproduction of prostaglandins. Biochem Pharmacol 1997; 53: 773-82.
    • (1997) Biochem Pharmacol , vol.53 , pp. 773-782
    • Pang, L.1    Hoult, J.R.2
  • 67
    • 0031575410 scopus 로고    scopus 로고
    • In vitro inhibition of proliferation of HL-60 cells by tetrandrine and coriolus versicolor peptide derived from Chinese medicinal herbs
    • Dong Y, Yang MM, Kwan CY. In vitro inhibition of proliferation of HL-60 cells by tetrandrine and coriolus versicolor peptide derived from Chinese medicinal herbs. Life Sci 1997; 60: PL135-40.
    • (1997) Life Sci , vol.60
    • Dong, Y.1    Yang, M.M.2    Kwan, C.Y.3
  • 68
    • 0025718742 scopus 로고
    • Demonstration of the induction of apoptosis (programmed cell death) by tetrandrine, a novel anti-inflammatory agent
    • Teh BS, Chen P, Lavin MF, Seow WK, Thong YH. Demonstration of the induction of apoptosis (programmed cell death) by tetrandrine, a novel anti-inflammatory agent. Int J Immunopharmacol 1991; 13: 1117-26.
    • (1991) Int J Immunopharmacol , vol.13 , pp. 1117-1126
    • Teh, B.S.1    Chen, P.2    Lavin, M.F.3    Seow, W.K.4    Thong, Y.H.5
  • 69
    • 0035337446 scopus 로고    scopus 로고
    • Western and Chinese antirheumatic drug-induced T cell apoptotic DNA damage uses different caspase cascades and is independent of Fas/Fas ligand interaction
    • Lai JH, Ho LJ, Lu KC, Chang DM, Shaio MF, Han SH. Western and Chinese antirheumatic drug-induced T cell apoptotic DNA damage uses different caspase cascades and is independent of Fas/Fas ligand interaction. J Immunol 2001; 166: 6914-24.
    • (2001) J Immunol , vol.166 , pp. 6914-6924
    • Lai, J.H.1    Ho, L.J.2    Lu, K.C.3    Chang, D.M.4    Shaio, M.F.5    Han, S.H.6
  • 70
    • 0029831787 scopus 로고    scopus 로고
    • Scavenging effect of tetrandrine of active oxygen radicals
    • Cao ZF. Scavenging effect of tetrandrine of active oxygen radicals. Planta Med 1996; 62: 413-4.
    • (1996) Planta Med , vol.62 , pp. 413-414
    • Cao, Z.F.1
  • 72
    • 0025361671 scopus 로고
    • Inhibition of active oxygen generation in guinea-pig neutrophils by biscoclaurine alkaloids
    • Matsuno T, Orita K, Edashige K, Kobuchi H, Sato EF, Inouye B, et al. Inhibition of active oxygen generation in guinea-pig neutrophils by biscoclaurine alkaloids. Biochem Pharmacol 1990; 39: 1255-9.
    • (1990) Biochem Pharmacol , vol.39 , pp. 1255-1259
    • Matsuno, T.1    Orita, K.2    Edashige, K.3    Kobuchi, H.4    Sato, E.F.5    Inouye, B.6
  • 74
    • 0033960220 scopus 로고    scopus 로고
    • On the role of hydroxyl radical and the effect of tetrandrine on nuclear factor-kappaB activation by phorbol 12-myristate 13-acetate
    • Ye J, Ding M, Zhang X, Rojanasakul Y, Shi X. On the role of hydroxyl radical and the effect of tetrandrine on nuclear factor-kappaB activation by phorbol 12-myristate 13-acetate. Ann Clin Lab Sci 2000; 30: 65-71.
    • (2000) Ann Clin Lab Sci , vol.30 , pp. 65-71
    • Ye, J.1    Ding, M.2    Zhang, X.3    Rojanasakul, Y.4    Shi, X.5
  • 75
    • 0031390081 scopus 로고    scopus 로고
    • Protective effect of tetrandrine on normal human mononuclear cells against ionizing irradiation
    • Chen YJ, Tu ML, Kuo HC, Chang KH, Lai YL, Chung CH, et al. Protective effect of tetrandrine on normal human mononuclear cells against ionizing irradiation. Biol Pharm Bull 1997; 20: 1160-4.
    • (1997) Biol Pharm Bull , vol.20 , pp. 1160-1164
    • Chen, Y.J.1    Tu, M.L.2    Kuo, H.C.3    Chang, K.H.4    Lai, Y.L.5    Chung, C.H.6
  • 76
    • 0032895283 scopus 로고    scopus 로고
    • Impediment to calcium influx and reactive oxygen production accounts for the inhibition of neutrophil Mac-1 Up-regulation and adhesion by tetrandrine
    • Shen YC, Chen CF, Wang SY, Sung YJ. Impediment to calcium influx and reactive oxygen production accounts for the inhibition of neutrophil Mac-1 Up-regulation and adhesion by tetrandrine. Mol Pharmacol 1999; 55: 186-93.
    • (1999) Mol Pharmacol , vol.55 , pp. 186-193
    • Shen, Y.C.1    Chen, C.F.2    Wang, S.Y.3    Sung, Y.J.4
  • 77
    • 0034757747 scopus 로고    scopus 로고
    • Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: Comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions
    • Shen YC, Chou CJ, Chiou WF, Chen CF. Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions. Mol Pharmacol 2001; 60: 1083-90.
    • (2001) Mol Pharmacol , vol.60 , pp. 1083-1090
    • Shen, Y.C.1    Chou, C.J.2    Chiou, W.F.3    Chen, C.F.4
  • 78
    • 0026531887 scopus 로고
    • Comparative effects of tetrandrine and berbamine on acute and relapsing experimental allergic encephalitis in Lewis rats
    • Wong CW, Seow WK, Thong YH. Comparative effects of tetrandrine and berbamine on acute and relapsing experimental allergic encephalitis in Lewis rats. Int Arch Allergy Immunol 1992; 97: 31-6.
    • (1992) Int Arch Allergy Immunol , vol.97 , pp. 31-36
    • Wong, C.W.1    Seow, W.K.2    Thong, Y.H.3
  • 79
    • 0026541955 scopus 로고
    • Comparative effects of tetrandrine and berbamine on production of the inflammatory cytokines interleukin-1 and tumor necrosis factor
    • Seow WK, Ferrante A, Summors A, Thong YH. Comparative effects of tetrandrine and berbamine on production of the inflammatory cytokines interleukin-1 and tumor necrosis factor. Life Sci 1992; 50: PL53-8.
    • (1992) Life Sci , vol.50
    • Seow, W.K.1    Ferrante, A.2    Summors, A.3    Thong, Y.H.4
  • 80
    • 0026687558 scopus 로고
    • Comparative effects of tetrandrine and berbamine on subcutaneous air pouch inflammation induced by interleukin-1, tumour necrosis factor and platelet-activating factor
    • Wong CW, Seow WK, O'Callaghan JW, Thong YH. Comparative effects of tetrandrine and berbamine on subcutaneous air pouch inflammation induced by interleukin-1, tumour necrosis factor and platelet-activating factor. Agents Actions 1992; 36: 112-8.
    • (1992) Agents Actions , vol.36 , pp. 112-118
    • Wong, C.W.1    Seow, W.K.2    O'Callaghan, J.W.3    Thong, Y.H.4
  • 81
    • 0024372372 scopus 로고
    • Anti-inflammatory and immunosuppressive properties of the bisbenzylisoquinolines: In vitro comparisons of tetrandrine and berbamine
    • Li SY, Ling LH, Teh BS, Seow WK, Thong YH. Anti-inflammatory and immunosuppressive properties of the bisbenzylisoquinolines: In vitro comparisons of tetrandrine and berbamine. Int J Immunopharmacol 1989; 11: 395-401.
    • (1989) Int J Immunopharmacol , vol.11 , pp. 395-401
    • Li, S.Y.1    Ling, L.H.2    Teh, B.S.3    Seow, W.K.4    Thong, Y.H.5
  • 82
    • 0025268483 scopus 로고
    • Inhibition of prostaglandin and leukotriene generation by the plant alkaloids tetrandrine and berbamine
    • Teh BS, Seow WK, Li SY, Thong YH. Inhibition of prostaglandin and leukotriene generation by the plant alkaloids tetrandrine and berbamine. Int J Immunopharmacol 1990; 12: 321-6.
    • (1990) Int J Immunopharmacol , vol.12 , pp. 321-326
    • Teh, B.S.1    Seow, W.K.2    Li, S.Y.3    Thong, Y.H.4
  • 83
    • 0025812893 scopus 로고
    • Comparative immunopharmacology and toxicology of the bisbenzylisoquinoline alkaloids tetrandrine and berbamine
    • Wong CW, Seow WK, Zeng TS, Halliday WJ, Thong YH. Comparative immunopharmacology and toxicology of the bisbenzylisoquinoline alkaloids tetrandrine and berbamine. Int J Immunopharmacol 1991; 13: 579-85.
    • (1991) Int J Immunopharmacol , vol.13 , pp. 579-585
    • Wong, C.W.1    Seow, W.K.2    Zeng, T.S.3    Halliday, W.J.4    Thong, Y.H.5


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