Plant alkaloid tetrandrine downregulates protein kinase C-dependent signaling pathway in T cells

European Journal of Pharmacology

Volumn 367, Issue 2-3, 1999, Pages 389-398

  Ho, Ling Jun ^a   Chang, Deh Ming ^b   Lee, Ta Chung ^c   Chang, Mu Lan ^b   Lai, Jenn Haung ^b  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c Army 802 Hospital   (Taiwan)

Author keywords

Apoptosis; Immunosuppression; Protein kinase C; T cell; Tetrandrine

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; HERNANDESINE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; PROTEIN KINASE C; TETRANDRINE;

APOPTOSIS; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; BLOOD; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SILICOSIS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ALKALOIDS; ANTIGENS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BENZYLISOQUINOLINES; CALCIUM CHANNEL BLOCKERS; CELL DIVISION; CYCLOSPORINE; DNA FRAGMENTATION; DOWN-REGULATION; DRUG SYNERGISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-2; IONOMYCIN; PROTEIN KINASE C; RECEPTORS, INTERLEUKIN-2; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE;

EID: 0033041740     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00941-8     Document Type: Article

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