메뉴 건너뛰기




Volumn 46, Issue 5, 2002, Pages 1335-1344

A conserved mitogen-activated protein kinase pathway is required for mating in Candida albicans

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHEROMONE; CEK1 PROTEIN, CANDIDA ALBICANS; CPH1 PROTEIN, CANDIDA ALBICANS; FUNGAL PROTEIN; FUS3 PROTEIN, S CEREVISIAE; MITOGEN ACTIVATED PROTEIN KINASE 3; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSCRIPTION FACTOR;

EID: 0036885807     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.03249.x     Document Type: Article
Times cited : (120)

References (42)
  • 1
    • 0032446353 scopus 로고    scopus 로고
    • Differential regulation of transcription: Repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins
    • Bardwell, L., Cook, J.G., Zhu-Shimoni, J.X., Voora, D., and Thorner, J. (1998) Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proc Natl Acad Sci USA 95: 15400-15405.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15400-15405
    • Bardwell, L.1    Cook, J.G.2    Zhu-Shimoni, J.X.3    Voora, D.4    Thorner, J.5
  • 2
    • 0035928744 scopus 로고    scopus 로고
    • MAPK specificity in the yeast pheromone response independent of transcriptional activation
    • Breitkreutz, A., Boucher, L., and Tyers, M. (2001) MAPK specificity in the yeast pheromone response independent of transcriptional activation. Curr Biol 11: 1266-1271.
    • (2001) Curr Biol , vol.11 , pp. 1266-1271
    • Breitkreutz, A.1    Boucher, L.2    Tyers, M.3
  • 3
    • 0034458993 scopus 로고    scopus 로고
    • Crk1, a novel Cdc2-related protein kinase, is required for hyphal development and virulence in Candida albicans
    • Chen, J., Zhou, S., Wang, Q., Chen, X., Pan, T., and Liu, H. (2000) Crk1, a novel Cdc2-related protein kinase, is required for hyphal development and virulence in Candida albicans. Mol Cell Biol 20: 8696-8708.
    • (2000) Mol Cell Biol , vol.20 , pp. 8696-8708
    • Chen, J.1    Zhou, S.2    Wang, Q.3    Chen, X.4    Pan, T.5    Liu, H.6
  • 4
    • 0029804618 scopus 로고    scopus 로고
    • Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae
    • Cook, J.G., Bardwell, L., Kron, S.J., and Thorner, J. (1996) Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev 10: 2831-2848.
    • (1996) Genes Dev , vol.10 , pp. 2831-2848
    • Cook, J.G.1    Bardwell, L.2    Kron, S.J.3    Thorner, J.4
  • 5
    • 0031596819 scopus 로고    scopus 로고
    • Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis
    • Csank, C., Schroppel, K., Leberer, E., Harcus, D., Mohamed, O., Meloche, S., et al. (1998) Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis. Infect Immun 66: 2713-2721.
    • (1998) Infect Immun , vol.66 , pp. 2713-2721
    • Csank, C.1    Schroppel, K.2    Leberer, E.3    Harcus, D.4    Mohamed, O.5    Meloche, S.6
  • 6
    • 0027525415 scopus 로고
    • Morphogenesis-independent regulation of actin transcript levels in the pathogenic yeast Candida albicans
    • Delbruck, S., and Ernst, J.F. (1993) Morphogenesis-independent regulation of actin transcript levels in the pathogenic yeast Candida albicans. Mol Microbiol 10: 859-866.
    • (1993) Mol Microbiol , vol.10 , pp. 859-866
    • Delbruck, S.1    Ernst, J.F.2
  • 7
    • 0033647489 scopus 로고    scopus 로고
    • Pheromone response, mating and cell biology
    • Elion, E.A. (2000) Pheromone response, mating and cell biology. Curr Opin Microbiol 3: 573-581.
    • (2000) Curr Opin Microbiol , vol.3 , pp. 573-581
    • Elion, E.A.1
  • 8
    • 0032692954 scopus 로고    scopus 로고
    • Ras signaling is required for serum-induced hyphal differentiation in Candida albicans
    • Feng, Q., Summers, E., Guo, B., and Fink, G. (1999) Ras signaling is required for serum-induced hyphal differentiation in Candida albicans. J Bacteriol 181: 6339-6346.
    • (1999) J Bacteriol , vol.181 , pp. 6339-6346
    • Feng, Q.1    Summers, E.2    Guo, B.3    Fink, G.4
  • 9
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albicans
    • Fonzi, W.A., and Irwin, M.Y. (1993) Isogenic strain construction and gene mapping in Candida albicans. Genetics 134: 717-728.
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 10
    • 0036151624 scopus 로고    scopus 로고
    • Hyphal elongation is regulated independently of cell cycle in Candida albicans
    • Hazan, I., Sepulveda-Becerra, M., and Liu, H. (2002) Hyphal elongation is regulated independently of cell cycle in Candida albicans. Mol Biol Cell 13: 134-145.
    • (2002) Mol Biol Cell , vol.13 , pp. 134-145
    • Hazan, I.1    Sepulveda-Becerra, M.2    Liu, H.3
  • 11
    • 0001225813 scopus 로고
    • Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae
    • Jones, E.W., Pringle, J.R., and Broach, J.R. (eds). New York: Cold Spring Harbor Laboratory Press
    • Herskowitz, I., Rine, J., and Strathern, J. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. In The Molecular and Cellular Biology of the Yeast Saccharomyces, Vol. 2. Jones, E.W., Pringle, J.R., and Broach, J.R. (eds). New York: Cold Spring Harbor Laboratory Press, pp. 583-656.
    • (1992) The Molecular and Cellular Biology of the Yeast Saccharomyces , vol.2 , pp. 583-656
    • Herskowitz, I.1    Rine, J.2    Strathern, J.3
  • 12
    • 0033588031 scopus 로고    scopus 로고
    • Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans
    • Hull, C.M., and Johnson, A.D. (1999) Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans. Science 285: 1271-1275.
    • (1999) Science , vol.285 , pp. 1271-1275
    • Hull, C.M.1    Johnson, A.D.2
  • 13
    • 0034647487 scopus 로고    scopus 로고
    • Evidence for mating of the 'asexual' yeast Candida albicans in a mammalian host
    • Hull, C.M., Raisner, R.M., and Johnson, A.D. (2000) Evidence for mating of the 'asexual' yeast Candida albicans in a mammalian host. Science 289: 307-310.
    • (2000) Science , vol.289 , pp. 307-310
    • Hull, C.M.1    Raisner, R.M.2    Johnson, A.D.3
  • 14
    • 0032574776 scopus 로고    scopus 로고
    • Monosomy of a specific chromosome determines L-sorbose utilization: A novel regulatory mechanism in Candida albicans
    • Janbon, G., Sherman, F., and Rustchenko, E. (1998) Monosomy of a specific chromosome determines L-sorbose utilization: a novel regulatory mechanism in Candida albicans. Proc Natl Acad Sci USA 95: 5150-5155.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5150-5155
    • Janbon, G.1    Sherman, F.2    Rustchenko, E.3
  • 15
    • 0029832793 scopus 로고    scopus 로고
    • Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development
    • Kohler, J.R., and Fink, G.R. (1996) Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development. Proc Natl Acad Sci USA 93: 13223-13228.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13223-13228
    • Kohler, J.R.1    Fink, G.R.2
  • 16
    • 0034811675 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor Cph2 regulates hyphal development in Candida albicans partly via TEC1
    • Lane, S., Zhou, S., Pan, T., Dai, Q., and Liu, H. (2001a) The basic helix-loop-helix transcription factor Cph2 regulates hyphal development in Candida albicans partly via TEC1. Mol Cell Biol 21: 6418-6428.
    • (2001) Mol Cell Biol , vol.21 , pp. 6418-6428
    • Lane, S.1    Zhou, S.2    Pan, T.3    Dai, Q.4    Liu, H.5
  • 17
    • 0035966045 scopus 로고    scopus 로고
    • DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans
    • Lane, S., Birse, C., Zhou, S., Matson, R., and Liu, H. (2001b) DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efgl in Candida albicans. J Biol Chem 276: 48988-48996.
    • (2001) J Biol Chem , vol.276 , pp. 48988-48996
    • Lane, S.1    Birse, C.2    Zhou, S.3    Matson, R.4    Liu, H.5
  • 18
    • 0027495599 scopus 로고
    • Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: Structural and functional similarity of Ste5 to Far1
    • Leberer, E., Dignard, D., Harcus, D., Hougan, L., Whiteway, M., and Thomas, D.Y. (1993) Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: structural and functional similarity of Ste5 to Far1. Mol Gen Genet 241: 241-254.
    • (1993) Mol Gen Genet , vol.241 , pp. 241-254
    • Leberer, E.1    Dignard, D.2    Harcus, D.3    Hougan, L.4    Whiteway, M.5    Thomas, D.Y.6
  • 19
    • 10544224146 scopus 로고    scopus 로고
    • Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans
    • Leberer, E., Harcus, D., Broadbent, I.D., Clark, K.L., Dignard, D., Ziegelbauer, K., et al. (1996) Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans. Proc Natl Acad Sci USA 93: 13217-13222.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13217-13222
    • Leberer, E.1    Harcus, D.2    Broadbent, I.D.3    Clark, K.L.4    Dignard, D.5    Ziegelbauer, K.6
  • 20
    • 84907128740 scopus 로고
    • An amino acid liquid synthetic medium for development of mycelial and yeast forms of Candida albicans
    • Lee, K.L., Buckley, H.R., and Campbell, C.C. (1975) An amino acid liquid synthetic medium for development of mycelial and yeast forms of Candida albicans. Sabouraudia 13: 148-153.
    • (1975) Sabouraudia , vol.13 , pp. 148-153
    • Lee, K.L.1    Buckley, H.R.2    Campbell, C.C.3
  • 22
    • 0035204231 scopus 로고    scopus 로고
    • Transcriptional control of dimorphism in Candida albicans
    • Liu, H. (2001) Transcriptional control of dimorphism in Candida albicans. Curr Opin Microbiol 4: 728-735.
    • (2001) Curr Opin Microbiol , vol.4 , pp. 728-735
    • Liu, H.1
  • 23
    • 0028569082 scopus 로고
    • Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog
    • Liu, H., Kohler, J., and Fink, G.R. (1994) Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog. Science 266: 1723-1726.
    • (1994) Science , vol.266 , pp. 1723-1726
    • Liu, H.1    Kohler, J.2    Fink, G.R.3
  • 24
    • 0032588942 scopus 로고    scopus 로고
    • A G1 cyclin is necessary for maintenance of filamentous growth in Candida albicans
    • Loeb, J.D., Sepulveda-Becerra, M., Hazan, I., and Liu, H. (1999) A G1 cyclin is necessary for maintenance of filamentous growth in Candida albicans. Mol Cell Biol 19: 4019-4027.
    • (1999) Mol Cell Biol , vol.19 , pp. 4019-4027
    • Loeb, J.D.1    Sepulveda-Becerra, M.2    Hazan, I.3    Liu, H.4
  • 25
    • 0031977016 scopus 로고    scopus 로고
    • The riddle of MAP kinase signaling specificity
    • Madhani, H.D., and Fink, G.R. (1998a) The riddle of MAP kinase signaling specificity. Trends Genet 14: 151-155.
    • (1998) Trends Genet , vol.14 , pp. 151-155
    • Madhani, H.D.1    Fink, G.R.2
  • 26
    • 0032169261 scopus 로고    scopus 로고
    • The control of filamentous differentiation and virulence in fungi
    • Madhani, H.D., and Fink, G.R. (1998b) The control of filamentous differentiation and virulence in fungi. Trends Celi Biol 8: 348-353.
    • (1998) Trends Celi Biol , vol.8 , pp. 348-353
    • Madhani, H.D.1    Fink, G.R.2
  • 27
    • 0030731714 scopus 로고    scopus 로고
    • MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
    • Madhani, H.D., Styles, C.A., and Fink, G.R. (1997) MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation. Cell 91: 673-684.
    • (1997) Cell , vol.91 , pp. 673-684
    • Madhani, H.D.1    Styles, C.A.2    Fink, G.R.3
  • 28
    • 0034647921 scopus 로고    scopus 로고
    • Induction of mating in Candida albicans by construction of MTLa and MTLalpha strains
    • Magee, B.B., and Magee, P.T. (2000) Induction of mating in Candida albicans by construction of MTLa and MTLalpha strains. Science 289: 310-313.
    • (2000) Science , vol.289 , pp. 310-313
    • Magee, B.B.1    Magee, P.T.2
  • 29
    • 0036886328 scopus 로고    scopus 로고
    • Many of the genes required for mating in Saccharomyces cerevisiae are also required for mating in Candida albicans
    • Magee, B.B., Legrand, M., Alarco A.-M., Raymond, M., and Magee P.T. (2002) Many of the genes required for mating in Saccharomyces cerevisiae are also required for mating in Candida albicans. Mol Microbiol 46: 1345-1351.
    • (2002) Mol Microbiol , vol.46 , pp. 1345-1351
    • Magee, B.B.1    Legrand, M.2    Alarco, A.-M.3    Raymond, M.4    Magee, P.T.5
  • 30
    • 0034076869 scopus 로고    scopus 로고
    • Two regulators of Ste12p inhibit pheromone-responsive transcription by separate mechanisms
    • Olson, K.A., Nelson, C., Tai, G., Hung, W., Yong, C., Astell, C., and Sadowski, I. (2000) Two regulators of Ste12p inhibit pheromone-responsive transcription by separate mechanisms. Mol Cell Biol 20: 4199-4209.
    • (2000) Mol Cell Biol , vol.20 , pp. 4199-4209
    • Olson, K.A.1    Nelson, C.2    Tai, G.3    Hung, W.4    Yong, C.5    Astell, C.6    Sadowski, I.7
  • 31
    • 0030832043 scopus 로고    scopus 로고
    • Transcriptional activation upon pheromone stimulation mediated by a small domain of Saccharomyces cerevisiae Ste12p
    • Pi, H., Chien, C.T., and Fields, S. (1997) Transcriptional activation upon pheromone stimulation mediated by a small domain of Saccharomyces cerevisiae Ste12p. Mol Cell Biol 17: 6410-6418.
    • (1997) Mol Cell Biol , vol.17 , pp. 6410-6418
    • Pi, H.1    Chien, C.T.2    Fields, S.3
  • 32
    • 0031974651 scopus 로고    scopus 로고
    • A Ste6p/P-glycoprote in homologue from the asexual yeast Candida albicans transports the a-factor mating pheromone in Saccharomyces cerevisiae
    • Raymond, M., Dignard, D., Alarco, A.M., Mainville, N., Magee, B.B., and Thomas, D.Y. (1998) A Ste6p/P-glycoprote in homologue from the asexual yeast Candida albicans transports the a-factor mating pheromone in Saccharomyces cerevisiae. Mol Microbiol 27: 587-598.
    • (1998) Mol Microbiol , vol.27 , pp. 587-598
    • Raymond, M.1    Dignard, D.2    Alarco, A.M.3    Mainville, N.4    Magee, B.B.5    Thomas, D.Y.6
  • 33
    • 0034796049 scopus 로고    scopus 로고
    • Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation
    • Sabbagh, W., Jr, Flatauer, L.J., Bardwell, A.J., and Bardwell, L. (2001) Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation. Mol Cell 8: 683-691.
    • (2001) Mol Cell , vol.8 , pp. 683-691
    • Sabbagh W., Jr.1    Flatauer, L.J.2    Bardwell, A.J.3    Bardwell, L.4
  • 34
    • 0026654255 scopus 로고
    • A G-protein alpha subunit from asexual Candida albicans functions in the mating signal transduction pathway of Saccharomyces cerevisiae and is regulated by the a1-alpha 2 repressor
    • Sadhu, C., Hoekstra, D., McEachern, M.J., Reed, S.I., and Hicks, J.B. (1992) A G-protein alpha subunit from asexual Candida albicans functions in the mating signal transduction pathway of Saccharomyces cerevisiae and is regulated by the a1-alpha 2 repressor. Mol Cell Biol 12: 1977-1985.
    • (1992) Mol Cell Biol , vol.12 , pp. 1977-1985
    • Sadhu, C.1    Hoekstra, D.2    McEachern, M.J.3    Reed, S.I.4    Hicks, J.B.5
  • 35
    • 0032927712 scopus 로고    scopus 로고
    • Host-induced, stage-specific virulence gene activation in Candida albicans during infection
    • Staib, P., Kretschmar, M., Nichterlein, T., Kohler, G., Michel, S., Hof, H., et al. (1999) Host-induced, stage-specific virulence gene activation in Candida albicans during infection. Mol Microbiol 32: 533-546.
    • (1999) Mol Microbiol , vol.32 , pp. 533-546
    • Staib, P.1    Kretschmar, M.2    Nichterlein, T.3    Kohler, G.4    Michel, S.5    Hof, H.6
  • 36
    • 0030945488 scopus 로고    scopus 로고
    • Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi
    • Stoldt, V.R., Sonneborn, A., Leuker, C.E., and Ernst, J.F. (1997) Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. EMBO J 16: 1982-1991.
    • (1997) EMBO J , vol.16 , pp. 1982-1991
    • Stoldt, V.R.1    Sonneborn, A.2    Leuker, C.E.3    Ernst, J.F.4
  • 37
    • 0031128205 scopus 로고    scopus 로고
    • Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates
    • Tedford, K., Kim, S., Sa, D., Stevens, K., and Tyers, M. (1997) Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates. Curr Biol 7: 228-238.
    • (1997) Curr Biol , vol.7 , pp. 228-238
    • Tedford, K.1    Kim, S.2    Sa, D.3    Stevens, K.4    Tyers, M.5
  • 39
    • 0023275830 scopus 로고
    • A family of yeast expression vectors containing the phage f1 intergenic region
    • Vernet, T., Dignard, D., and Thomas, D.Y. (1987) A family of yeast expression vectors containing the phage f1 intergenic region. Gene 52: 225-233.
    • (1987) Gene , vol.52 , pp. 225-233
    • Vernet, T.1    Dignard, D.2    Thomas, D.Y.3
  • 40
    • 0019450566 scopus 로고
    • Natural heterozygosity in Candida albicans
    • Whelan, W.L., and Magee, P.T. (1981) Natural heterozygosity in Candida albicans. J Bacteriol 145: 896-903.
    • (1981) J Bacteriol , vol.145 , pp. 896-903
    • Whelan, W.L.1    Magee, P.T.2
  • 41
    • 0026686669 scopus 로고
    • Dominant negative selection of heterologous genes: Isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest
    • Whiteway, M., Dignard, D., and Thomas, D.Y. (1992) Dominant negative selection of heterologous genes: isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest. Proc Natl Acad Sci USA 89: 9410-9414.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9410-9414
    • Whiteway, M.1    Dignard, D.2    Thomas, D.Y.3
  • 42
    • 0033028595 scopus 로고    scopus 로고
    • Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions
    • Wilson, R.B., Davis, D., and Mitchell, A.P. (1999) Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions. J Bacteriol 181: 1868-1874.
    • (1999) J Bacteriol , vol.181 , pp. 1868-1874
    • Wilson, R.B.1    Davis, D.2    Mitchell, A.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.