Transcriptional control of dimorphism in Candida albicans

Current Opinion in Microbiology

Volumn 4, Issue 6, 2001, Pages 728-735

  Liu, Haoping ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN CDC42; PROTEIN CPH1; PROTEIN EFG1; PROTEIN NRG1; PROTEIN RFG1; PROTEIN RIM101; PROTEIN TUP1; REPRESSOR PROTEIN; SEPTIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CZF1; TRANSCRIPTION FACTOR TEC1; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

CANDIDA ALBICANS; CELL CYCLE; CELL SPECIFICITY; CELL STRUCTURE; ENZYME MECHANISM; FUNGAL GENETICS; FUNGUS HYPHAE; GENE EXPRESSION REGULATION; MORPHOGENESIS; NONHUMAN; PHASE TRANSITION; PROTEIN LOCALIZATION; REPRESSOR GENE; REVIEW; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VIRULENCE;

CANDIDA ALBICANS; FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0035204231     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(01)00275-2     Document Type: Review

References (56)

1. Regulatory networks controlling Candida albicans morphogenesis
2. Transcription factors in Candida albicans environmental control of morphogenesis
3. Transcriptional control of cell type and morphogenesis in Candida albicans
4. Genomic evidence for a complete sexual cycle in Candida albicans
5. Signal transduction cascades regulating fungal development and virulence
6. CAP1, an adenylate cyclase-associated protein gene, regulates bud-hypha transitions, filamentous growth, and cyclic AMP levels and is required for virulence of Candida albicans
7. Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae
8. Ras signaling is required for serum-induced hyphal differentiation in Candida albicans
9. Protein kinase A encoded by TPK2 regulates dimorphism of Candida albicans
10. The three yeast A kinases have specific signaling functions in pseudohyphal growth
11. Nonfilamentous C. albicans mutants are avirulent
12. Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi
13. Sok2 regulates yeast pseudohyphal differentiation via a transcription factor cascade that regulates cell-cell adhesion
14. A positive regulator of mitosis, Sok2, functions as a negative regulator of meiosis in Saccharomyces cerevisiae
15. A potential phosphorylation site for an A type kinase in the Efgl regulator protein contributes to hyphal morphogenesis of Candida albicans
16. Efg1, a morphogenetic regulator in Candida albicans, is a sequence-specific DNA binding protein
17. Crk1, a novel Cdc2 related protein kinase, is required for hyphal development and virulence in Candida albicans
18. Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity
19. Ras regulates the polarity of the yeast actin cytoskeleton through the stress response pathway
20. Sfl1 functions via the co-repressor Ssn6-Tup1 and the cAMP-dependent protein kinase Tpk2
21. The TEA/ATTS transcription factor CaTec1 p regulates hyphal development and virulence in Candida albicans
22. Combinatorial control required for the specificity of yeast MAPK signaling
23. The basic helix-loop-helix transcription factor cph2 regulates hyphal development in Candida albicans partly via Tec1
24. Control of filament formation in Candida albicans by the transcriptional repressor TUP1
25. Identification and characterization of TUP1-regulated genes in Candida albicans
26. TUP1, CPH1 and EFG1 make independent contributions to filamentation in Candida albicans
27. Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Rox1, controls filamentous growth and virulence in Candida albicans
28. The DNA binding protein Rfg1 is a repressor of filamentation in Candida albicans
29. NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans
30. NRG1, a repressor of filamentous growth in C. albicans, is down-regulated during filament induction
31. Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae
32. PRR1, a homolog of Aspergillus nidulans paIf, controls pH-dependent gene expression and filamentation in Candida albicans
33. Effects of environmental pH on morphological development of Candida albicans is mediated via the PacC-related transcription factor encoded by PRR2
34. RIM101-dependent and -independent pathways govern pH responses in Candida albicans
35. Dominant active alleles of RIM101 (PRR2) bypass the pH restriction on filamentation of Candida albicans
36. Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene
37. Role of the mitogen-activated protein kinase Hog1 p in morphogenesis and virulence of Candida albicans
38. HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF1
39. Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1
40. Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans
41. Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis
42. Repression of hyphal proteinase expression by the mitogen-activated protein (MAP) kinase phosphatase Cpp1 p of Candida albicans is independent of the MAP kinase Cekl p
43. EFG1 null mutants of Candida albicans switch but cannot express the complete phenotype of white-phase budding cells
44. Differences in actin localization during bud and hypha formation in the yeast Candida albicans
45. Cell polarity and hyphal morphogenesis are controlled by multiple rho- protein modules in the filamentous ascomycete Ashbya gossypii
46. Virulence and hyphal formation of Candida albicans require the Ste20p-like protein kinase CaCla4p
47. A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii
48. Temporal and spatial regulation of Rho-type guanine-nucleotide exchange factors: The yeast perspective
49. A G1 cyclin is necessary for maintenance of filamentous growth in Candida albicans
50. Hyphal elongation is independent of cell cycle in Candida albicans
51. The germ tube of Candida albicans hyphae and Pseudohyphae show different patterns of septin ring localization
52. Role of the yeast Gin4p protein kinase in septin assembly and the relationship between septin assembly and septin function
53. Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis
54. Candida albicans Int1 p interacts with the septin ring in yeast and hyphal cells
55. Candida albicans INT1-induced filamentation in Saccharomyces cerevisiae depends on Sla2p
56. Isolation of the M1G1 gene from Candida albicans and effects of its disruption on catabolite repression