-
1
-
-
0027494653
-
The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction
-
Muller, M., J. Briscoe, C. Laxton, D. Guschin, A. Ziemiecki, O. Silvennoinen, A. G. Harpur, G. Barbieri, B. A. Witthuhn, C. Schindler, et al. 1993. The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction. Nature 366:129.
-
(1993)
Nature
, vol.366
, pp. 129
-
-
Muller, M.1
Briscoe, J.2
Laxton, C.3
Guschin, D.4
Ziemiecki, A.5
Silvennoinen, O.6
Harpur, A.G.7
Barbieri, G.8
Witthuhn, B.A.9
Schindler, C.10
-
2
-
-
0027914818
-
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-γ signal transduction pathway
-
Watling, D., D. Guschin, M. Muller, O. Silvennoinen, B. A. Witthuhn, F. W. Quelle, N. C. Rogers, C. Schindler, G. R. Stark, J. N. Ihle, et al. 1993. Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-γ signal transduction pathway. Nature 366:166.
-
(1993)
Nature
, vol.366
, pp. 166
-
-
Watling, D.1
Guschin, D.2
Muller, M.3
Silvennoinen, O.4
Witthuhn, B.A.5
Quelle, F.W.6
Rogers, N.C.7
Schindler, C.8
Stark, G.R.9
Ihle, J.N.10
-
3
-
-
0028845212
-
Cytokine receptor signalling
-
Ihle, J. N. 1995. Cytokine receptor signalling. Nature 377:591.
-
(1995)
Nature
, vol.377
, pp. 591
-
-
Ihle, J.N.1
-
4
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J. E., Jr., I. M. Kerr, and G. R. Stark. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415.
-
(1994)
Science
, vol.264
, pp. 1415
-
-
Darnell J.E., Jr.1
Kerr, I.M.2
Stark, G.R.3
-
5
-
-
0030704646
-
Jaks and Stats in cytokine signaling
-
Ihle, J. N., T. Nosaka, W. Thierfelder, F. W. Quelle, and K. Shimoda. 1997. Jaks and Stats in cytokine signaling. Stem Cells 15(Suppl. 1):105.
-
(1997)
Stem Cells
, vol.15
, Issue.SUPPL. 1
, pp. 105
-
-
Ihle, J.N.1
Nosaka, T.2
Thierfelder, W.3
Quelle, F.W.4
Shimoda, K.5
-
6
-
-
0026632288
-
A protein tyrosine kinase in the interferon cdr3 signaling pathway
-
Velazquez, L., M. Fellous, G. R. Stark, and S. Pellegrini. 1992. A protein tyrosine kinase in the interferon cdr3 signaling pathway. Cell 70:313.
-
(1992)
Cell
, vol.70
, pp. 313
-
-
Velazquez, L.1
Fellous, M.2
Stark, G.R.3
Pellegrini, S.4
-
7
-
-
0033711641
-
Tyk2 plays a restricted role in IFNα signaling, although it is required for IL-12-mediated T cell function
-
Shimoda, K., K. Kato, K. Aoki, T. Matsuda, A. Miyamoto, M. Shibamori, M. Yamashita, A. Numata, K. Takase, S. Kobayashi, et al. 2000. Tyk2 plays a restricted role in IFNα signaling, although it is required for IL-12-mediated T cell function. Immunity 13:561.
-
(2000)
Immunity
, vol.13
, pp. 561
-
-
Shimoda, K.1
Kato, K.2
Aoki, K.3
Matsuda, T.4
Miyamoto, A.5
Shibamori, M.6
Yamashita, M.7
Numata, A.8
Takase, K.9
Kobayashi, S.10
-
8
-
-
0033696404
-
Partial impairment of cytokine responses in Tyk2-deficient mice
-
Karaghiosoff, M., H. Neubauer, C. Lassnig, P. Kovarik, H. Schindler, H. Pircher, B. McCoy, C. Bogdan, T. Decker, G. Brem, et al. 2000. Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity 13:549.
-
(2000)
Immunity
, vol.13
, pp. 549
-
-
Karaghiosoff, M.1
Neubauer, H.2
Lassnig, C.3
Kovarik, P.4
Schindler, H.5
Pircher, H.6
McCoy, B.7
Bogdan, C.8
Decker, T.9
Brem, G.10
-
9
-
-
0032076183
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
Rodig, S. J., M. A. Meraz, J. M. White, P. A. Lampe, J. K. Riley, C. D. Arthur, K. L. King, K. C. Sheehan, L. Yin, D. Pennica, et al. 1998. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 93:373.
-
(1998)
Cell
, vol.93
, pp. 373
-
-
Rodig, S.J.1
Meraz, M.A.2
White, J.M.3
Lampe, P.A.4
Riley, J.K.5
Arthur, C.D.6
King, K.L.7
Sheehan, K.C.8
Yin, L.9
Pennica, D.10
-
10
-
-
13344282731
-
Targeted disruption of the Statl gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz, M. A., J. M. White, K. C. Sheehan, E. A. Bach, S. J. Rodig, A. S. Dighe, D. H. Kaplan, J. K. Riley, A. C. Greenlund, D. Campbell, et al. 1996. Targeted disruption of the Statl gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84:431.
-
(1996)
Cell
, vol.84
, pp. 431
-
-
Meraz, M.A.1
White, J.M.2
Sheehan, K.C.3
Bach, E.A.4
Rodig, S.J.5
Dighe, A.S.6
Kaplan, D.H.7
Riley, J.K.8
Greenlund, A.C.9
Campbell, D.10
-
11
-
-
0030024563
-
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
-
Durbin, J. E., R. Hackenmiller, M. C. Simon, and D. E. Levy. 1996. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84:443.
-
(1996)
Cell
, vol.84
, pp. 443
-
-
Durbin, J.E.1
Hackenmiller, R.2
Simon, M.C.3
Levy, D.E.4
-
12
-
-
0034515268
-
Immune response in Stat2 knockout mice
-
Park, C., S. Li, E. Cha, and C. Schindler. 2000. Immune response in Stat2 knockout mice. Immunity 13:795.
-
(2000)
Immunity
, vol.13
, pp. 795
-
-
Park, C.1
Li, S.2
Cha, E.3
Schindler, C.4
-
13
-
-
0031962665
-
Impairment of T and B cell development by treatment with a type I interferon
-
Lin, Q., C. Dong, and M. D. Cooper. 1998. Impairment of T and B cell development by treatment with a type I interferon. J. Exp. Med. 187:79.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 79
-
-
Lin, Q.1
Dong, C.2
Cooper, M.D.3
-
14
-
-
0034284454
-
Stat-1 is not essential for inhibition of B lymphopoiesis by type I IFNs
-
Gongora, R., R. P. Stephan, R. D. Schreiber, and M. D. Cooper. 2000. Stat-1 is not essential for inhibition of B lymphopoiesis by type I IFNs. J. Immunol. 165:2362.
-
(2000)
J. Immunol.
, vol.165
, pp. 2362
-
-
Gongora, R.1
Stephan, R.P.2
Schreiber, R.D.3
Cooper, M.D.4
-
15
-
-
0034948684
-
An essential role for Daxx in the inhibition of B lymphopoiesis by type I interferons
-
Gongora, R., R. P. Stephan, Z. Zhang, and M. D. Cooper. 2001. An essential role for Daxx in the inhibition of B lymphopoiesis by type I interferons. Immunity 14:727.
-
(2001)
Immunity
, vol.14
, pp. 727
-
-
Gongora, R.1
Stephan, R.P.2
Zhang, Z.3
Cooper, M.D.4
-
16
-
-
0027331409
-
Suppression of B lymphopoiesis during normal pregnancy
-
Medina, K. L., G. Smithson, and P. W. Kincade. 1993. Suppression of B lymphopoiesis during normal pregnancy. J. Exp. Med. 178:1507.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1507
-
-
Medina, K.L.1
Smithson, G.2
Kincade, P.W.3
-
17
-
-
0035031325
-
Limitin: An interferon-like cytokine without myeloerythroid suppressive properties
-
Oritani, K., P. W. Kincade, and Y. Tomiyama. 2001. Limitin: An interferon-like cytokine without myeloerythroid suppressive properties. J. Mol. Med. 79:168.
-
(2001)
J. Mol. Med.
, vol.79
, pp. 168
-
-
Oritani, K.1
Kincade, P.W.2
Tomiyama, Y.3
-
18
-
-
0025737489
-
Support of early B-cell differentiation in mouse fetal liver by stromal cells and interleukin-7
-
Gunji, Y., T. Sudo, J. Suda, Y. Yamaguchi, H. Nakauchi, S. Nishikawa, N. Yanai, M. Obinata, M. Yanagisawa, Y. Miura, et al. 1991. Support of early B-cell differentiation in mouse fetal liver by stromal cells and interleukin-7. Blood 77:2612.
-
(1991)
Blood
, vol.77
, pp. 2612
-
-
Gunji, Y.1
Sudo, T.2
Suda, J.3
Yamaguchi, Y.4
Nakauchi, H.5
Nishikawa, S.6
Yanai, N.7
Obinata, M.8
Yanagisawa, M.9
Miura, Y.10
-
19
-
-
0030754121
-
Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colonystimulating factor
-
Shimoda, K., J. Feng, H. Murakami, S. Nagata, D. Watling, N. C. Rogers, G. R. Stark, I. M. Kerr, and J. N. Ihle. 1997. Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colonystimulating factor. Blood 90:597.
-
(1997)
Blood
, vol.90
, pp. 597
-
-
Shimoda, K.1
Feng, J.2
Murakami, H.3
Nagata, S.4
Watling, D.5
Rogers, N.C.6
Stark, G.R.7
Kerr, I.M.8
Ihle, J.N.9
-
20
-
-
0024282606
-
Stimulation of B-cell progenitors by cloned murine interleukin-7
-
Namen, A. E., S. Lupton, K. Hjerrild, J. Wignall, D. Y. Mochizuki, A. Schmierer, B. Mosley, C. J. March, D. Urdal, and S. Gillis. 1988. Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature 333:571.
-
(1988)
Nature
, vol.333
, pp. 571
-
-
Namen, A.E.1
Lupton, S.2
Hjerrild, K.3
Wignall, J.4
Mochizuki, D.Y.5
Schmierer, A.6
Mosley, B.7
March, C.J.8
Urdal, D.9
Gillis, S.10
-
21
-
-
0032544309
-
Activation of apoptosis signal-regulating kinase I (ASK1) by the adapter protein Daxx
-
Chang, H. Y., H. Nishitoh, X. Yang, H. Ichijo, and D. Baltimore. 1998. Activation of apoptosis signal-regulating kinase I (ASK1) by the adapter protein Daxx. Science 281:1860.
-
(1998)
Science
, vol.281
, pp. 1860
-
-
Chang, H.Y.1
Nishitoh, H.2
Yang, X.3
Ichijo, H.4
Baltimore, D.5
-
22
-
-
0034906821
-
TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation
-
Perlman, R., W. P. Schiemann, M. W. Brooks, H. F. Lodish, and R. A. Weinberg. 2001. TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation. Nat. Cell Biol. 3:708.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 708
-
-
Perlman, R.1
Schiemann, W.P.2
Brooks, M.W.3
Lodish, H.F.4
Weinberg, R.A.5
-
23
-
-
0031587883
-
Daxx, a novel Fas-binding protein that activates JNK and apoptosis
-
Yang, X., R. Khosravi-Far, H. Y. Chang, and D. Baltimore. 1997. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89:1067.
-
(1997)
Cell
, vol.89
, pp. 1067
-
-
Yang, X.1
Khosravi-Far, R.2
Chang, H.Y.3
Baltimore, D.4
-
24
-
-
0033574058
-
Dissecting Fas signaling with an altered-specificity death-domain mutant: Requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation
-
Chang, H. Y., X. Yang, and D. Baltimore. 1999. Dissecting Fas signaling with an altered-specificity death-domain mutant: Requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proc. Natl. Acad. Sci. USA 96:1252.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.896
, pp. 1252
-
-
Chang, H.Y.1
Yang, X.2
Baltimore, D.3
-
25
-
-
0030892234
-
Apoptosis by death factor
-
Nagata, S. 1997. Apoptosis by death factor. Cell 88:355.
-
(1997)
Cell
, vol.88
, pp. 355
-
-
Nagata, S.1
-
26
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin, M. P., T. M. Goncharov, Y. V. Goltsev, and D. Wallach. 1996. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85:803.
-
(1996)
Cell
, vol.85
, pp. 803
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
27
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
Muzio, M., A. M. Chinnaiyan, F. C. Kischkel, K. O'Rourke, A. Shevchenko, J. Ni, C. Scaffidi, J. D. Bretz, M. Zhang, R. Gentz, et al. 1996. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85:817.
-
(1996)
Cell
, vol.85
, pp. 817
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
-
28
-
-
0033179775
-
Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development
-
Michaelson, J. S., D. Bader, F. Kuo, C. Kozak, and P. Leder. 1999. Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development. Genes Dev. 13:1918.
-
(1999)
Genes Dev.
, vol.13
, pp. 1918
-
-
Michaelson, J.S.1
Bader, D.2
Kuo, F.3
Kozak, C.4
Leder, P.5
-
29
-
-
0028009763
-
Lymphoma models for B cell activation and tolerance. X. Anti-μ-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc
-
Fischer, G., S. C. Kent, L. Joseph, D. R. Green, and D. W. Scott. 1994. Lymphoma models for B cell activation and tolerance. X. Anti-μ-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc. J. Exp. Med. 179:221.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 221
-
-
Fischer, G.1
Kent, S.C.2
Joseph, L.3
Green, D.R.4
Scott, D.W.5
-
30
-
-
0033229827
-
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs)
-
Torii, S., D. A. Egan, R. A. Evans, and J. C. Reed. 1999. Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs). EMBO J. 18:6037.
-
(1999)
EMBO J.
, vol.18
, pp. 6037
-
-
Torii, S.1
Egan, D.A.2
Evans, R.A.3
Reed, J.C.4
-
31
-
-
0034695883
-
Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis
-
Zhong, S., P. Salomoni, S. Ronchetti, A. Guo, D. Ruggero, and P. P. Pandolfi. 2000. Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. J. Exp. Med. 191:631.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 631
-
-
Zhong, S.1
Salomoni, P.2
Ronchetti, S.3
Guo, A.4
Ruggero, D.5
Pandolfi, P.P.6
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