Functional aspects of co-variant surface charges in an antibody fragment

Protein Science

Volumn 11, Issue 11, 2002, Pages 2697-2705

  Hugo, Nicolas ^a   Lafont, Virginie ^b   Beukes, Mervyn ^b   Altschuh, Danièle ^a,b  

^a Biotechnologie de Strasbourg   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Antibody surface charges; Antigen binding properties; Biacore; Co variance; Half life; Recombinant protein yield

Indexed keywords

ANTIBODY; GUANIDINE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; ANTIGEN; PEPTIDE; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ARTICLE; BIOTECHNOLOGY; CYTOPLASM; HALF LIFE TIME; KINETICS; MUTATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DENATURATION; PROTEIN FOLDING; ANTIGEN ANTIBODY REACTION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; SURFACE PROPERTY;

ANTIGEN-ANTIBODY REACTIONS; ANTIGENS; GUANIDINE; HALF-LIFE; IMMUNOGLOBULIN VARIABLE REGION; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDES; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SURFACE PROPERTIES;

EID: 0036838270     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0209302     Document Type: Article

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