New variation on a theme: Structure and mechanism of action of hydrolytic antibody 7F11, an aspartate rich relation of catalytic antibodies 17E8 and 29G11

Journal of Immunological Methods

Volumn 269, Issue 1-2, 2002, Pages 173-195

  Cross, Simon S J ^a   Brady, Kevin ^a   Stevenson, James D ^a   Sackin, Jenny R ^a   Kenward, Nigel ^a   Dietel, Anja ^a   Thomas, Neil R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Aspartate proteinases; AutoDock; Catalytic antibody; Chemiluminescence; Homology model; Molecular dynamics simulation

Indexed keywords

ANTIBODY 17E8; ANTIBODY 29G11; ANTIBODY 7F11; ASPARTATE PROTEINASE; ASPARTIC ACID DERIVATIVE; BENZOATE ESTER; BENZOIC ACID DERIVATIVE; CATALYTIC ANTIBODY; HAPTEN; PEPSIN A; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBODY COMBINING SITE; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; CATALYSIS; CHEMOLUMINESCENCE; COMPUTER MODEL; HYDROLYSIS; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; SIMULATION;

ANTIBODIES, CATALYTIC; ASPARTIC ACID; COMPUTER SIMULATION; GENE EXPRESSION; HYDROLYSIS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036837165     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(02)00232-6     Document Type: Article

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