A chemiluminescent catalytic antibody

Chemical Communications

Volumn , Issue 20, 1999, Pages 2105-2106

  Stevenson, James D ^a   Dietel, Anja ^a   Thomas, Neil R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOIC ACID; CATALYTIC ANTIBODY; ESTER; MONOCLONAL ANTIBODY; PHOSPHONIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY COMBINING SITE; ARTICLE; CHEMOLUMINESCENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; HYBRIDOMA; MOUSE; NONHUMAN;

EID: 0033592615     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/a906566k     Document Type: Article

References (26)

1. Reviews: D. R. Liu and P. G. Schultz, Angew. Chem., Int. Ed., 1999, 38, 36; J.-L. Reymond, Top. Curr. Chem., 1999, 200, 59; G. M. Blackburn, A. Datta, H. Denham and P. Wentworth, Adv. Phys. Org. Chem., 1998, 31, 249; N. R. Thomas, Nat. Prod. Rep., 1996, 13, 479.
2. Reviews: D. R. Liu and P. G. Schultz, Angew. Chem., Int. Ed., 1999, 38, 36; J.-L. Reymond, Top. Curr. Chem., 1999, 200, 59; G. M. Blackburn, A. Datta, H. Denham and P. Wentworth, Adv. Phys. Org. Chem., 1998, 31, 249; N. R. Thomas, Nat. Prod. Rep., 1996, 13, 479.
3. Reviews: D. R. Liu and P. G. Schultz, Angew. Chem., Int. Ed., 1999, 38, 36; J.-L. Reymond, Top. Curr. Chem., 1999, 200, 59; G. M. Blackburn, A. Datta, H. Denham and P. Wentworth, Adv. Phys. Org. Chem., 1998, 31, 249; N. R. Thomas, Nat. Prod. Rep., 1996, 13, 479.
4. Reviews: D. R. Liu and P. G. Schultz, Angew. Chem., Int. Ed., 1999, 38, 36; J.-L. Reymond, Top. Curr. Chem., 1999, 200, 59; G. M. Blackburn, A. Datta, H. Denham and P. Wentworth, Adv. Phys. Org. Chem., 1998, 31, 249; N. R. Thomas, Nat. Prod. Rep., 1996, 13, 479.
5. J. R. Crowther, ELISA Theory & Practice, Humana Press, Totowa, New Jersey, 1995.
6. A synthesis for an alternative hapten and proposed antibody chemiluminescence reaction was reported during the course of this work: M. Sawa, Y. Imaeda, J. Hiratake, R. Fujii, R. Umeshita, M. Watanabe, H. Kondo and J. Oda, Bioorg. Med. Chem. Lett., 1998, 8, 647. However the generation of an antibody catalyst by these workers has yet to be reported. A catalytic antibody for the luminol-peroxidase reaction has also been reported: L. J. Kricka and X. Ji, Biolumin. Chemilum.: Proc. Int. Symp. 7th 1993, 1993, 518. The authors were not able to demonstrate unequivocally that this activity, which was short-lived, was not due to a contaminating enzyme, or purely a hydrophobic effect.
7. A synthesis for an alternative hapten and proposed antibody chemiluminescence reaction was reported during the course of this work: M. Sawa, Y. Imaeda, J. Hiratake, R. Fujii, R. Umeshita, M. Watanabe, H. Kondo and J. Oda, Bioorg. Med. Chem. Lett., 1998, 8, 647. However the generation of an antibody catalyst by these workers has yet to be reported. A catalytic antibody for the luminol-peroxidase reaction has also been reported: L. J. Kricka and X. Ji, Biolumin. Chemilum.: Proc. Int. Symp. 7th 1993, 1993, 518. The authors were not able to demonstrate unequivocally that this activity, which was short-lived, was not due to a contaminating enzyme, or purely a hydrophobic effect.
8. J. A. Smiley and S. J. Benkovic, Proc. Natl. Acad. Sci. U.S.A., 1994, 91, 8319.
9. N. Bensel, N. Bahr, M. T. Reymond, C. Schenkels and J.-L. Reymond, Helv. Chim. Acta, 1999, 82, 44
10. B. Avalle, S. Vanwetswinkel and J. Fastrez, Bioog. Med. Chem. Lett., 1997, 7, 479; C. F. Barbas, A. Heine, G. F. Zhong, T. Hoffman, S. Gramatikova, R. Bjornestedt, B. List, J. Anderson, E. A. Stura, I. A. Wilson and R. A. Lerner, Science, 1997, 278, 2085.
11. B. Avalle, S. Vanwetswinkel and J. Fastrez, Bioog. Med. Chem. Lett., 1997, 7, 479; C. F. Barbas, A. Heine, G. F. Zhong, T. Hoffman, S. Gramatikova, R. Bjornestedt, B. List, J. Anderson, E. A. Stura, I. A. Wilson and R. A. Lerner, Science, 1997, 278, 2085.
12. F. Taran, P. Y. Renard, C. Creminon, A. Valleix, Y. Frobert, P. Pradelles, J. Grassi and C. Mioskowski, Tetrahedron Lett., 1999, 40, 1887, 1891; G. Macbeath and D. Hilvert, J. Am. Chem. Soc., 1994, 116, 6106; D. S. Tawfik, B. S. Green, R. Chap, M. Sela and Z. Eshhar, Proc. Natl. Acad. Sci. U.S.A., 1993, 90, 373.
13. F. Taran, P. Y. Renard, C. Creminon, A. Valleix, Y. Frobert, P. Pradelles, J. Grassi and C. Mioskowski, Tetrahedron Lett., 1999, 40, 1887, 1891; G. Macbeath and D. Hilvert, J. Am. Chem. Soc., 1994, 116, 6106; D. S. Tawfik, B. S. Green, R. Chap, M. Sela and Z. Eshhar, Proc. Natl. Acad. Sci. U.S.A., 1993, 90, 373.
14. F. Taran, P. Y. Renard, C. Creminon, A. Valleix, Y. Frobert, P. Pradelles, J. Grassi and C. Mioskowski, Tetrahedron Lett., 1999, 40, 1887, 1891; G. Macbeath and D. Hilvert, J. Am. Chem. Soc., 1994, 116, 6106; D. S. Tawfik, B. S. Green, R. Chap, M. Sela and Z. Eshhar, Proc. Natl. Acad. Sci. U.S.A., 1993, 90, 373.
15. J.-L. Jestin, P. Kristensen and G.Winter, Angew. Chem., Int. Ed., 1999, 38, 1196; H. Pedersen, S. Hölder, D. P. Sutherlin, U. Schwitter, D. S. King and P. G. Schultz, Proc. Natl. Acad. Sci. U.S.A., 1998, 95, 10523.
16. J.-L. Jestin, P. Kristensen and G.Winter, Angew. Chem., Int. Ed., 1999, 38, 1196; H. Pedersen, S. Hölder, D. P. Sutherlin, U. Schwitter, D. S. King and P. G. Schultz, Proc. Natl. Acad. Sci. U.S.A., 1998, 95, 10523.
17. L. E. Janes, A. C. Lowendahl and R. J. Kazlauskas, Chem. Eur. J., 1998, 4, 2324.
18. A. P. Schaap, R. S. Handley and B. P. Giri, Tetrahedron Lett., 1987, 28, 935; S. Beck and H. Köster, Anal. Chem., 1990, 62, 2258; A. P. Schaap and H. Akhavan-Tafti, US Patent (U.S.P. WO90/07511) 1990; W. Adam, I. Bronstein, A. V. Tromfimov and R. F. Vasilev, J. Am. Chem. Soc., 1999, 121, 958.
19. A. P. Schaap, R. S. Handley and B. P. Giri, Tetrahedron Lett., 1987, 28, 935; S. Beck and H. Köster, Anal. Chem., 1990, 62, 2258; A. P. Schaap and H. Akhavan-Tafti, US Patent (U.S.P. WO90/07511) 1990; W. Adam, I. Bronstein, A. V. Tromfimov and R. F. Vasilev, J. Am. Chem. Soc., 1999, 121, 958.
20. A. P. Schaap, R. S. Handley and B. P. Giri, Tetrahedron Lett., 1987, 28, 935; S. Beck and H. Köster, Anal. Chem., 1990, 62, 2258; A. P. Schaap and H. Akhavan-Tafti, US Patent (U.S.P. WO90/07511) 1990; W. Adam, I. Bronstein, A. V. Tromfimov and R. F. Vasilev, J. Am. Chem. Soc., 1999, 121, 958.
21. A. P. Schaap, R. S. Handley and B. P. Giri, Tetrahedron Lett., 1987, 28, 935; S. Beck and H. Köster, Anal. Chem., 1990, 62, 2258; A. P. Schaap and H. Akhavan-Tafti, US Patent (U.S.P. WO90/07511) 1990; W. Adam, I. Bronstein, A. V. Tromfimov and R. F. Vasilev, J. Am. Chem. Soc., 1999, 121, 958.
22. G. T. Hermanson, Bioconjugate Techniques, AP, San Diego, 1996, p. 169.
23. R. B. Saishidhar, A. K. Capoor and D. Ramana, J. Immunol. Methods, 1994, 167, 121. An average hapten density of 24 copies of 1 per BSA was found, whilst 49% of the free lysines in the polymeric KLH had been derivatised.
24. E. Harlow and D. Lane, Antibodies: A Laboratory Manual, Cold Spring Harbor, New York, 1988.
25. R. Curci, L. Lopez, L. Troisi, S. M. K. Rashid and A. P. Schaap, Tetrahedron Lett., 1987, 28, 5319.
26. R. E. Kontermann, P. Martineau, C. E. Cummings, A. Karpas, D. Allen, E. Derbyshire and G. Winter, Immunotechnology, 1997, 3, 137.