The neuroprotective agents chlomethiazole and SB203580 inhibit IL-1β signalling but not its biosynthesis in rat cortical glial cells

Journal of Neurochemistry

Volumn 83, Issue 3, 2002, Pages 727-737

  Simi, Anastasia ^a   Porsmyr Palmertz, Margareta ^a   Hjertén, Anna ^a   Ingelman Sundberg, Magnus ^a   Tindberg, Niclas ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Chlomethiazole; Glia; Interleukin 1 ; Neuroprotection; p38 MAP kinase

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CLOMETHIAZOLE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GLIA CELL; MONOCYTE; NEUROPROTECTION; NEWBORN; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; CEREBRAL CORTEX; CHLORMETHIAZOLE; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEEDBACK, BIOCHEMICAL; IMIDAZOLES; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROGLIA; NEUROPROTECTIVE AGENTS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-FOS; PYRIDINES; RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0036829772     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01178.x     Document Type: Article

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