메뉴 건너뛰기




Volumn 16, Issue 10, 1998, Pages 961-965

Formation of A Catalytically Active Dimer by tRNAval -driven Short Ribozymes

Author keywords

Antisense; Gene inactivation; Minizymes

Indexed keywords

DIMER; RIBOZYME; TRANSFER RNA;

EID: 3543096756     PISSN: 0733222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1098-961     Document Type: Article
Times cited : (64)

References (42)
  • 1
    • 0024436928 scopus 로고
    • Self-cleavage of RNA in the replication of small pathogens of plants and animals
    • Symons, R.H. 1989. Self-cleavage of RNA in the replication of small pathogens of plants and animals. Trends Biochem. Sci. 14:445-450.
    • (1989) Trends Biochem. Sci , vol.14 , pp. 445-450
    • Symons, R.H.1
  • 2
    • 0026666130 scopus 로고
    • A trinucleotide can promote metal ion-dependent specific cleavage of RNA
    • Kazakov, S. and Altman, S. 1992. A trinucleotide can promote metal ion-dependent specific cleavage of RNA. Proc. Natl. Acad. Sci. USA 89:7939-7943.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7939-7943
    • Kazakov, S.1    Altman, S.2
  • 3
    • 0027398505 scopus 로고
    • Metal ion catalysis in the Tetrahymena ribozyme reaction
    • Piccirilli, J.A., Vyle, J.S., Caruthers, M.H., and Cech, T.R. 1993. Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature 361:85-88.
    • (1993) Nature , vol.361 , pp. 85-88
    • Piccirilli, J.A.1    Vyle, J.S.2    Caruthers, M.H.3    Cech, T.R.4
  • 4
    • 0025998488 scopus 로고
    • Role of divalent metal ions in the hammerhead RNA cleavage reaction
    • Dahm, S.C, Derrick, W.B., and Uhlenbeck, O.C. 1993. Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry 30:9464-9469.
    • (1993) Biochemistry , vol.30 , pp. 9464-9469
    • Dahm, S.C.1    Derrick, W.B.2    Uhlenbeck, O.C.3
  • 5
    • 0027184481 scopus 로고
    • A general two-metal-ion mechanism for catalytic RNA
    • Steitz, T.A. and Steitz, J.A. 1993. A general two-metal-ion mechanism for catalytic RNA. Proc. Natl. Acad. Sci. USA 90:6498-6502.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6498-6502
    • Steitz, T.A.1    Steitz, J.A.2
  • 7
    • 0030800470 scopus 로고    scopus 로고
    • A second catalytic metal ion on group 1 ribozyme
    • Weinstein, L.B., Jones, B.C., Cosstick, R., and Cech, T.R. 1997. A second catalytic metal ion on group 1 ribozyme. Nature 388:805-808.
    • (1997) Nature , vol.388 , pp. 805-808
    • Weinstein, L.B.1    Jones, B.C.2    Cosstick, R.3    Cech, T.R.4
  • 8
    • 0029168512 scopus 로고
    • Kinetic evidence based on solvent isotope effects for the nonexistence of a proton-transfer process in reactions catalyzed by a hammerhead ribozyme: Implication to the double-metal-ion mechanism of catalysis
    • Sawata, S., Komiyama, M., and Taira, K. 1995. Kinetic evidence based on solvent isotope effects for the nonexistence of a proton-transfer process in reactions catalyzed by a hammerhead ribozyme: implication to the double-metal-ion mechanism of catalysis. J. Am. Chem. Soc. 117:2357-2358.
    • (1995) J. Am. Chem. Soc , vol.117 , pp. 2357-2358
    • Sawata, S.1    Komiyama, M.2    Taira, K.3
  • 9
    • 0031461748 scopus 로고    scopus 로고
    • Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion-effects on the cleavage rates of 5′-oxy and 5′-thio substrates by a hammerhead ribozyme
    • Zhou, D.-M., Zhang, L.-H., and Taira, K. 1997. Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion-effects on the cleavage rates of 5′-oxy and 5′-thio substrates by a hammerhead ribozyme. Proc. Natl. Acad. Sci. USA 94:14343-14348.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14343-14348
    • Zhou, D.-M.1    Zhang, L.-H.2    Taira, K.3
  • 10
    • 0031882388 scopus 로고    scopus 로고
    • A two metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate
    • Lott, W.B., Pontius, B.W., and von Hippei, P.H. 1998. A two metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate. Proc. Natl. Acad. Sci. USA 95:542-547.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 542-547
    • Lott, W.B.1    Pontius, B.W.2    Von Hippei, P.H.3
  • 11
    • 11544373758 scopus 로고    scopus 로고
    • The hydrolysis of RNA: From theoretical calculations to the hammerhead ribozyme-mediated cleavage of RNA
    • Zhou, D.-M., and Taira, K. 1998. The hydrolysis of RNA: from theoretical calculations to the hammerhead ribozyme-mediated cleavage of RNA. Chem. Rev. 98:991-1026.
    • (1998) Chem. Rev , vol.98 , pp. 991-1026
    • Zhou, D.-M.1    Taira, K.2
  • 12
    • 0028063567 scopus 로고
    • Three-dimensional structure of a hammerhead ribozyme
    • Pley, H.W., Flaherty, K.M., and Mackay, D.B. 1994. Three-dimensional structure of a hammerhead ribozyme. Nature 372:68-74.
    • (1994) Nature , vol.372 , pp. 68-74
    • Pley, H.W.1    Flaherty, K.M.2    Mackay, D.B.3
  • 13
    • 0029073091 scopus 로고
    • The crystal structure of an all-RNA hammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage
    • Scott, W.G., Finch, J.T., and Klug, A. 1995. The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage. Cell 81:991-1002.
    • (1995) Cell , vol.81 , pp. 991-1002
    • Scott, W.G.1    Finch, J.T.2    Klug, A.3
  • 14
    • 0030476765 scopus 로고    scopus 로고
    • Capturing the structure of a catalytic RNA intermediate: The hammerhead ribozyme
    • Scott, W.G., Murray, J.B., Arnold, J.R.R, Stoddard, B.L, and Klug, A. 1996. Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science 274:2065-2069.
    • (1996) Science , vol.274 , pp. 2065-2069
    • Scott, W.G.1    Murray, J.B.2    Arnold, J.3    Stoddard, B.L.4    Klug, A.5
  • 16
    • 0027250866 scopus 로고
    • Hammerhead ribozymes: Importance of stem-loop II activity
    • Tuschl, T. and Eckstein, F. 1993. Hammerhead ribozymes: importance of stem-loop II activity. Proc. Natl. Acad. Sci. USA 90:6991-6994.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6991-6994
    • Tuschl, T.1    Eckstein, F.2
  • 17
    • 0028083574 scopus 로고
    • Hammerhead ribozymes containing non-nucleoside linkers are active RNA catalysts
    • Fu, D.J., Benseler, F, and Mclaughlin, L.W. 1994. Hammerhead ribozymes containing non-nucleoside linkers are active RNA catalysts. J. Am. Chem. Soc. 116:4591-4598.
    • (1994) J. Am. Chem. Soc , vol.116 , pp. 4591-4598
    • Fu, D.J.1    Benseler, F.2    McLaughlin, L.W.3
  • 18
    • 0028339955 scopus 로고
    • Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions
    • Long, D.M. and Uhlenbeck, O.C. 1994. Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions. Proc. Natl. Acad. Sci. USA 91:6977-6981.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6977-6981
    • Long, D.M.1    Uhlenbeck, O.C.2
  • 19
    • 0029886439 scopus 로고    scopus 로고
    • Hammerhead minizymes with high cleavage activity: A dimeric structure as the active conformation of minizymes
    • Amontov, S. and Taira, K. 1996. Hammerhead minizymes with high cleavage activity: a dimeric structure as the active conformation of minizymes. J. Am. Chem. Soc. 118:1624-1628.
    • (1996) J. Am. Chem. Soc , vol.118 , pp. 1624-1628
    • Amontov, S.1    Taira, K.2
  • 20
    • 0029932871 scopus 로고    scopus 로고
    • Characterization of several kinds of dimer minizyme: Simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes
    • Kuwabara, T, Amontov, S., Warashina, M., Ohkawa, J., and Taira, K. 1996. Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes. Nucleic Acids Res. 24:2302-2310.
    • (1996) Nucleic Acids Res , vol.24 , pp. 2302-2310
    • Kuwabara, T.1    Amontov, S.2    Warashina, M.3    Ohkawa, J.4    Taira, K.5
  • 22
    • 0030629511 scopus 로고    scopus 로고
    • TRNA-delivery systems for ribozymes
    • Turner, PC. (ed.). Humana Press, Totowa, NJ
    • Perriman, R. and de Feyter, R. 1997. tRNA-delivery systems for ribozymes, pp. 393-402 in Methods in molecular biology, ribozyme protocols. Turner, PC. (ed.). Humana Press, Totowa, NJ.
    • (1997) Methods in Molecular Biology, Ribozyme Protocols , pp. 393-402
    • Perriman, R.1    De Feyter, R.2
  • 23
    • 0029997458 scopus 로고    scopus 로고
    • Magnesium-mediated conversion of an inactive form of a hammerhead ribozyme to an active complex with its substrate. An investigation by NMR spectroscopy
    • Orita, M., Vinayak, R., Andrus, A., Warashina, M., Chiba, A., Kaniwa, H. et al. 1996. Magnesium-mediated conversion of an inactive form of a hammerhead ribozyme to an active complex with its substrate. An investigation by NMR spectroscopy. J. Biol. Chem. 271:9447-9454.
    • (1996) J. Biol. Chem , vol.271 , pp. 9447-9454
    • Orita, M.1    Vinayak, R.2    Rus, A.3    Warashina, M.4    Chiba, A.5    Kaniwa, H.6
  • 24
    • 0025363891 scopus 로고
    • Ribozymes as potential anti-HIV-1 therapeutic agents
    • Sarver, N., Cantin, E., Chang, P., Ladne, P., Stephens, D., Zaia, J. et al. 1990. Ribozymes as potential anti-HIV-1 therapeutic agents. Science 247:1222-1225.
    • (1990) Science , vol.247 , pp. 1222-1225
    • Sarver, N.1    Cantin, E.2    Chang, P.3    Ladne, P.4    Stephens, D.5    Zaia, J.6
  • 25
    • 0027367947 scopus 로고
    • RNA enzyme-directed gene therapy
    • Altman, S. 1993. RNA enzyme-directed gene therapy. Proc. Natl. Acad. Sci. USA 90:10898-10900.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10898-10900
    • Altman, S.1
  • 27
    • 0027987902 scopus 로고
    • Ribozyme-mediated repair of defective mRNA by targeted frans-splicing
    • Sullenger, B.A. and Cech, T.R. 1994. Ribozyme-mediated repair of defective mRNA by targeted frans-splicing. Waiure 371:619-622.
    • (1994) Waiure , vol.371 , pp. 619-622
    • Sullenger, B.A.1    Cech, T.R.2
  • 28
    • 0029781202 scopus 로고    scopus 로고
    • Ex vivo transduction and expansion of CD4+ lymphocytes from HIV+ donors: Prelude to a ribozyme gene therapy trial
    • Leavitt, M.C., Yu, M., Wong-Staal, F, and Looney, D.J. 1996. Ex vivo transduction and expansion of CD4+ lymphocytes from HIV+ donors: prelude to a ribozyme gene therapy trial. Gene Ther. 3:599-606.
    • (1996) Gene Ther , vol.3 , pp. 599-606
    • Leavitt, M.C.1    Yu, M.2    Wong-Staal, F.3    Looney, D.J.4
  • 30
    • 0003387327 scopus 로고    scopus 로고
    • The use of ribozymes to inhibit HIV replication
    • Eckstein, F. and Lilley, D.M.J, (eds.). Springer-Verlag Press, Berlin, Germany
    • Sun, L.-Q., Gerlach, W.L., and Symonds, G. 1996. The use of ribozymes to inhibit HIV replication, pp. 329-342, in Catalytic RNA. nucleic acids and molecular biology, Vol. 10. Eckstein, F. and Lilley, D.M.J, (eds.). Springer-Verlag Press, Berlin, Germany.
    • (1996) Catalytic RNA. Nucleic Acids and Molecular Biology , vol.10 , pp. 329-342
    • Sun, L.-Q.1    Gerlach, W.L.2    Symonds, G.3
  • 31
    • 0028051280 scopus 로고
    • Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1
    • Yamada, O., Yu, M., Yee, J.-K., Kraus, G., Looney, D., and Wong-Staal, F. 1994. Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1. Gene Ther. 1:38-45.
    • (1994) Gene Ther , vol.1 , pp. 38-45
    • Yamada, O.1    Yu, M.2    Yee, J.-K.3    Kraus, G.4    Looney, D.5    Wong-Staal, F.6
  • 33
    • 0028876680 scopus 로고
    • Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1
    • Yu, M., Leavitt, M.C., Maruyama, M., Yamada, O., Young, D., Ho, A.D. et al. 1995. Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 92:699-703.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 699-703
    • Yu, M.1    Leavitt, M.C.2    Maruyama, M.3    Yamada, O.4    Young, D.5    Ho, A.D.6
  • 34
    • 0030056765 scopus 로고    scopus 로고
    • Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (P300) and luciferase
    • Kawasaki, H., Ohkawa, J., Tanishige, N., Yoshinari, K., Murata, T., Yokoyama, K.K. et al. 1996. Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (p300) and luciferase. Nucleic Acids Res. 24:3010-3016.
    • (1996) Nucleic Acids Res , vol.24 , pp. 3010-3016
    • Kawasaki, H.1    Ohkawa, J.2    Tanishige, N.3    Yoshinari, K.4    Murata, T.5    Yokoyama, K.K.6
  • 35
    • 12644252947 scopus 로고    scopus 로고
    • The expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization
    • Bertrand, E., Castanotto, D., Zhou, C, Carbonnele, O, Lee, N.S., Good, R et al. 1997. The expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization. RNA 3:75-88.
    • (1997) RNA , vol.3 , pp. 75-88
    • Bertrand, E.1    Castanotto, D.2    Zhou, C.3    Carbonnele, O.4    Lee, N.S.5    Good, R.6
  • 36
    • 0032554825 scopus 로고    scopus 로고
    • Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation
    • Kawasaki, H., Eckner, R., Yao, T.-P., Taira, K., Chiu, R., Livingston, D.M. et al. 1998. Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. Nature 393:284-289.
    • (1998) Nature , vol.393 , pp. 284-289
    • Kawasaki, H.1    Eckner, R.2    Yao, T.-P.3    Taira, K.4    Chiu, R.5    Livingston, D.M.6
  • 37
    • 0026542605 scopus 로고
    • Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1
    • Heidenreich, O. and Eckstein, F. 1992. Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1. J. Biol. Chem. 267:1904-1909.
    • (1992) J. Biol. Chem , vol.267 , pp. 1904-1909
    • Heidenreich, O.1    Eckstein, F.2
  • 38
    • 0027435063 scopus 로고
    • Importance of independence in ribozyme reactions: Kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus
    • Ohkawa, J., Yuyama, N., Takebe, Y, Nishikawa, S., and Taira, K. 1993. Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 90:11302-11306.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11302-11306
    • Ohkawa, J.1    Yuyama, N.2    Takebe, Y.3    Nishikawa, S.4    Taira, K.5
  • 42
    • 0032580454 scopus 로고    scopus 로고
    • A simple assay system for examination of the inhibitory potential in vivo of decoy RNAs, ribozymes and other drugs by measuring the Tat-mediated transcription of fusion gene composed of the long terminal repeat of HIV-1 and a gene for luciferase
    • Koseki, S., Ohkawa, J., Yamamoto, R., Takebe, Y, and Taira, K. 1998. A simple assay system for examination of the inhibitory potential in vivo of decoy RNAs, ribozymes and other drugs by measuring the Tat-mediated transcription of fusion gene composed of the long terminal repeat of HIV-1 and a gene for luciferase. J. Controlled Release 53:159-173.
    • (1998) J. Controlled Release , vol.53 , pp. 159-173
    • Koseki, S.1    Ohkawa, J.2    Yamamoto, R.3    Takebe, Y.4    Taira, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.