-
1
-
-
0024436928
-
Self-cleavage of RNA in the replication of small pathogens of plants and animals
-
Symons, R.H. 1989. Self-cleavage of RNA in the replication of small pathogens of plants and animals. Trends Biochem. Sci. 14:445-450.
-
(1989)
Trends Biochem. Sci
, vol.14
, pp. 445-450
-
-
Symons, R.H.1
-
2
-
-
0026666130
-
A trinucleotide can promote metal ion-dependent specific cleavage of RNA
-
Kazakov, S. and Altman, S. 1992. A trinucleotide can promote metal ion-dependent specific cleavage of RNA. Proc. Natl. Acad. Sci. USA 89:7939-7943.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7939-7943
-
-
Kazakov, S.1
Altman, S.2
-
3
-
-
0027398505
-
Metal ion catalysis in the Tetrahymena ribozyme reaction
-
Piccirilli, J.A., Vyle, J.S., Caruthers, M.H., and Cech, T.R. 1993. Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature 361:85-88.
-
(1993)
Nature
, vol.361
, pp. 85-88
-
-
Piccirilli, J.A.1
Vyle, J.S.2
Caruthers, M.H.3
Cech, T.R.4
-
4
-
-
0025998488
-
Role of divalent metal ions in the hammerhead RNA cleavage reaction
-
Dahm, S.C, Derrick, W.B., and Uhlenbeck, O.C. 1993. Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry 30:9464-9469.
-
(1993)
Biochemistry
, vol.30
, pp. 9464-9469
-
-
Dahm, S.C.1
Derrick, W.B.2
Uhlenbeck, O.C.3
-
5
-
-
0027184481
-
A general two-metal-ion mechanism for catalytic RNA
-
Steitz, T.A. and Steitz, J.A. 1993. A general two-metal-ion mechanism for catalytic RNA. Proc. Natl. Acad. Sci. USA 90:6498-6502.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6498-6502
-
-
Steitz, T.A.1
Steitz, J.A.2
-
6
-
-
0003448574
-
-
Springer-Verlag Press, Berlin, Germany
-
Eckstein, F., and Lilley, D.M.J. (eds.). 1996. Catalytic RNA nucleic acids and molecular biology. Vol. 10. Springer-Verlag Press, Berlin, Germany.
-
(1996)
Catalytic RNA Nucleic Acids and Molecular Biology
, vol.10
-
-
Eckstein, F.1
Lilley, D.M.J.2
-
7
-
-
0030800470
-
A second catalytic metal ion on group 1 ribozyme
-
Weinstein, L.B., Jones, B.C., Cosstick, R., and Cech, T.R. 1997. A second catalytic metal ion on group 1 ribozyme. Nature 388:805-808.
-
(1997)
Nature
, vol.388
, pp. 805-808
-
-
Weinstein, L.B.1
Jones, B.C.2
Cosstick, R.3
Cech, T.R.4
-
8
-
-
0029168512
-
Kinetic evidence based on solvent isotope effects for the nonexistence of a proton-transfer process in reactions catalyzed by a hammerhead ribozyme: Implication to the double-metal-ion mechanism of catalysis
-
Sawata, S., Komiyama, M., and Taira, K. 1995. Kinetic evidence based on solvent isotope effects for the nonexistence of a proton-transfer process in reactions catalyzed by a hammerhead ribozyme: implication to the double-metal-ion mechanism of catalysis. J. Am. Chem. Soc. 117:2357-2358.
-
(1995)
J. Am. Chem. Soc
, vol.117
, pp. 2357-2358
-
-
Sawata, S.1
Komiyama, M.2
Taira, K.3
-
9
-
-
0031461748
-
Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion-effects on the cleavage rates of 5′-oxy and 5′-thio substrates by a hammerhead ribozyme
-
Zhou, D.-M., Zhang, L.-H., and Taira, K. 1997. Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion-effects on the cleavage rates of 5′-oxy and 5′-thio substrates by a hammerhead ribozyme. Proc. Natl. Acad. Sci. USA 94:14343-14348.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14343-14348
-
-
Zhou, D.-M.1
Zhang, L.-H.2
Taira, K.3
-
10
-
-
0031882388
-
A two metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate
-
Lott, W.B., Pontius, B.W., and von Hippei, P.H. 1998. A two metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate. Proc. Natl. Acad. Sci. USA 95:542-547.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 542-547
-
-
Lott, W.B.1
Pontius, B.W.2
Von Hippei, P.H.3
-
11
-
-
11544373758
-
The hydrolysis of RNA: From theoretical calculations to the hammerhead ribozyme-mediated cleavage of RNA
-
Zhou, D.-M., and Taira, K. 1998. The hydrolysis of RNA: from theoretical calculations to the hammerhead ribozyme-mediated cleavage of RNA. Chem. Rev. 98:991-1026.
-
(1998)
Chem. Rev
, vol.98
, pp. 991-1026
-
-
Zhou, D.-M.1
Taira, K.2
-
12
-
-
0028063567
-
Three-dimensional structure of a hammerhead ribozyme
-
Pley, H.W., Flaherty, K.M., and Mackay, D.B. 1994. Three-dimensional structure of a hammerhead ribozyme. Nature 372:68-74.
-
(1994)
Nature
, vol.372
, pp. 68-74
-
-
Pley, H.W.1
Flaherty, K.M.2
Mackay, D.B.3
-
13
-
-
0029073091
-
The crystal structure of an all-RNA hammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage
-
Scott, W.G., Finch, J.T., and Klug, A. 1995. The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage. Cell 81:991-1002.
-
(1995)
Cell
, vol.81
, pp. 991-1002
-
-
Scott, W.G.1
Finch, J.T.2
Klug, A.3
-
14
-
-
0030476765
-
Capturing the structure of a catalytic RNA intermediate: The hammerhead ribozyme
-
Scott, W.G., Murray, J.B., Arnold, J.R.R, Stoddard, B.L, and Klug, A. 1996. Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science 274:2065-2069.
-
(1996)
Science
, vol.274
, pp. 2065-2069
-
-
Scott, W.G.1
Murray, J.B.2
Arnold, J.3
Stoddard, B.L.4
Klug, A.5
-
15
-
-
0026686191
-
Minimal sequence requirements for ribozyme activity
-
McCall, M.J., Hendry, P., and Jennings, PA. 1992. Minimal sequence requirements for ribozyme activity. Proc. Natl. Acad. Sci. USA 89:5710-5714.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5710-5714
-
-
McCall, M.J.1
Hendry, P.2
Jennings, P.A.3
-
16
-
-
0027250866
-
Hammerhead ribozymes: Importance of stem-loop II activity
-
Tuschl, T. and Eckstein, F. 1993. Hammerhead ribozymes: importance of stem-loop II activity. Proc. Natl. Acad. Sci. USA 90:6991-6994.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6991-6994
-
-
Tuschl, T.1
Eckstein, F.2
-
17
-
-
0028083574
-
Hammerhead ribozymes containing non-nucleoside linkers are active RNA catalysts
-
Fu, D.J., Benseler, F, and Mclaughlin, L.W. 1994. Hammerhead ribozymes containing non-nucleoside linkers are active RNA catalysts. J. Am. Chem. Soc. 116:4591-4598.
-
(1994)
J. Am. Chem. Soc
, vol.116
, pp. 4591-4598
-
-
Fu, D.J.1
Benseler, F.2
McLaughlin, L.W.3
-
18
-
-
0028339955
-
Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions
-
Long, D.M. and Uhlenbeck, O.C. 1994. Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions. Proc. Natl. Acad. Sci. USA 91:6977-6981.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6977-6981
-
-
Long, D.M.1
Uhlenbeck, O.C.2
-
19
-
-
0029886439
-
Hammerhead minizymes with high cleavage activity: A dimeric structure as the active conformation of minizymes
-
Amontov, S. and Taira, K. 1996. Hammerhead minizymes with high cleavage activity: a dimeric structure as the active conformation of minizymes. J. Am. Chem. Soc. 118:1624-1628.
-
(1996)
J. Am. Chem. Soc
, vol.118
, pp. 1624-1628
-
-
Amontov, S.1
Taira, K.2
-
20
-
-
0029932871
-
Characterization of several kinds of dimer minizyme: Simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes
-
Kuwabara, T, Amontov, S., Warashina, M., Ohkawa, J., and Taira, K. 1996. Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes. Nucleic Acids Res. 24:2302-2310.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2302-2310
-
-
Kuwabara, T.1
Amontov, S.2
Warashina, M.3
Ohkawa, J.4
Taira, K.5
-
22
-
-
0030629511
-
TRNA-delivery systems for ribozymes
-
Turner, PC. (ed.). Humana Press, Totowa, NJ
-
Perriman, R. and de Feyter, R. 1997. tRNA-delivery systems for ribozymes, pp. 393-402 in Methods in molecular biology, ribozyme protocols. Turner, PC. (ed.). Humana Press, Totowa, NJ.
-
(1997)
Methods in Molecular Biology, Ribozyme Protocols
, pp. 393-402
-
-
Perriman, R.1
De Feyter, R.2
-
23
-
-
0029997458
-
Magnesium-mediated conversion of an inactive form of a hammerhead ribozyme to an active complex with its substrate. An investigation by NMR spectroscopy
-
Orita, M., Vinayak, R., Andrus, A., Warashina, M., Chiba, A., Kaniwa, H. et al. 1996. Magnesium-mediated conversion of an inactive form of a hammerhead ribozyme to an active complex with its substrate. An investigation by NMR spectroscopy. J. Biol. Chem. 271:9447-9454.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 9447-9454
-
-
Orita, M.1
Vinayak, R.2
Rus, A.3
Warashina, M.4
Chiba, A.5
Kaniwa, H.6
-
24
-
-
0025363891
-
Ribozymes as potential anti-HIV-1 therapeutic agents
-
Sarver, N., Cantin, E., Chang, P., Ladne, P., Stephens, D., Zaia, J. et al. 1990. Ribozymes as potential anti-HIV-1 therapeutic agents. Science 247:1222-1225.
-
(1990)
Science
, vol.247
, pp. 1222-1225
-
-
Sarver, N.1
Cantin, E.2
Chang, P.3
Ladne, P.4
Stephens, D.5
Zaia, J.6
-
25
-
-
0027367947
-
RNA enzyme-directed gene therapy
-
Altman, S. 1993. RNA enzyme-directed gene therapy. Proc. Natl. Acad. Sci. USA 90:10898-10900.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10898-10900
-
-
Altman, S.1
-
26
-
-
0028650692
-
Inhibition of gene expression with ribozymes
-
Marschall, P., Thomson, J.B., and Eckstein, F. 1994. Inhibition of gene expression with ribozymes. Cell Mol. Neurobiol. 14:523-538.
-
(1994)
Cell Mol. Neurobiol
, vol.14
, pp. 523-538
-
-
Marschall, P.1
Thomson, J.B.2
Eckstein, F.3
-
27
-
-
0027987902
-
Ribozyme-mediated repair of defective mRNA by targeted frans-splicing
-
Sullenger, B.A. and Cech, T.R. 1994. Ribozyme-mediated repair of defective mRNA by targeted frans-splicing. Waiure 371:619-622.
-
(1994)
Waiure
, vol.371
, pp. 619-622
-
-
Sullenger, B.A.1
Cech, T.R.2
-
28
-
-
0029781202
-
Ex vivo transduction and expansion of CD4+ lymphocytes from HIV+ donors: Prelude to a ribozyme gene therapy trial
-
Leavitt, M.C., Yu, M., Wong-Staal, F, and Looney, D.J. 1996. Ex vivo transduction and expansion of CD4+ lymphocytes from HIV+ donors: prelude to a ribozyme gene therapy trial. Gene Ther. 3:599-606.
-
(1996)
Gene Ther
, vol.3
, pp. 599-606
-
-
Leavitt, M.C.1
Yu, M.2
Wong-Staal, F.3
Looney, D.J.4
-
29
-
-
8044253998
-
Expression of small, therapeutic RNAs in human cell nuclei
-
Good, P.J., Krikos, A.J., Li, S.X., Bertrand, E., Lee, N.S., Giver, L. et al. 1997. Expression of small, therapeutic RNAs in human cell nuclei. Gene Ther. 4:45-54.
-
(1997)
Gene Ther
, vol.4
, pp. 45-54
-
-
Good, P.J.1
Krikos, A.J.2
Li, S.X.3
Bertrand, E.4
Lee, N.S.5
Giver, L.6
-
30
-
-
0003387327
-
The use of ribozymes to inhibit HIV replication
-
Eckstein, F. and Lilley, D.M.J, (eds.). Springer-Verlag Press, Berlin, Germany
-
Sun, L.-Q., Gerlach, W.L., and Symonds, G. 1996. The use of ribozymes to inhibit HIV replication, pp. 329-342, in Catalytic RNA. nucleic acids and molecular biology, Vol. 10. Eckstein, F. and Lilley, D.M.J, (eds.). Springer-Verlag Press, Berlin, Germany.
-
(1996)
Catalytic RNA. Nucleic Acids and Molecular Biology
, vol.10
, pp. 329-342
-
-
Sun, L.-Q.1
Gerlach, W.L.2
Symonds, G.3
-
31
-
-
0028051280
-
Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1
-
Yamada, O., Yu, M., Yee, J.-K., Kraus, G., Looney, D., and Wong-Staal, F. 1994. Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1. Gene Ther. 1:38-45.
-
(1994)
Gene Ther
, vol.1
, pp. 38-45
-
-
Yamada, O.1
Yu, M.2
Yee, J.-K.3
Kraus, G.4
Looney, D.5
Wong-Staal, F.6
-
32
-
-
0028147059
-
Construction and characterization of Ick- and fyn-specific tRNA:Ribozyme chimeras
-
Baier, G., Coggeshall, K.M., Baier-Bitterlich, G., Giampa, L., Telford, D., Herbert, E. et al. 1994. Construction and characterization of Ick- and fyn-specific tRNA:ribozyme chimeras. Mol. Immunol. 31:923-932.
-
(1994)
Mol. Immunol
, vol.31
, pp. 923-932
-
-
Baier, G.1
Coggeshall, K.M.2
Baier-Bitterlich, G.3
Giampa, L.4
Telford, D.5
Herbert, E.6
-
33
-
-
0028876680
-
Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1
-
Yu, M., Leavitt, M.C., Maruyama, M., Yamada, O., Young, D., Ho, A.D. et al. 1995. Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 92:699-703.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 699-703
-
-
Yu, M.1
Leavitt, M.C.2
Maruyama, M.3
Yamada, O.4
Young, D.5
Ho, A.D.6
-
34
-
-
0030056765
-
Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (P300) and luciferase
-
Kawasaki, H., Ohkawa, J., Tanishige, N., Yoshinari, K., Murata, T., Yokoyama, K.K. et al. 1996. Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (p300) and luciferase. Nucleic Acids Res. 24:3010-3016.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 3010-3016
-
-
Kawasaki, H.1
Ohkawa, J.2
Tanishige, N.3
Yoshinari, K.4
Murata, T.5
Yokoyama, K.K.6
-
35
-
-
12644252947
-
The expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization
-
Bertrand, E., Castanotto, D., Zhou, C, Carbonnele, O, Lee, N.S., Good, R et al. 1997. The expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization. RNA 3:75-88.
-
(1997)
RNA
, vol.3
, pp. 75-88
-
-
Bertrand, E.1
Castanotto, D.2
Zhou, C.3
Carbonnele, O.4
Lee, N.S.5
Good, R.6
-
36
-
-
0032554825
-
Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation
-
Kawasaki, H., Eckner, R., Yao, T.-P., Taira, K., Chiu, R., Livingston, D.M. et al. 1998. Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. Nature 393:284-289.
-
(1998)
Nature
, vol.393
, pp. 284-289
-
-
Kawasaki, H.1
Eckner, R.2
Yao, T.-P.3
Taira, K.4
Chiu, R.5
Livingston, D.M.6
-
37
-
-
0026542605
-
Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1
-
Heidenreich, O. and Eckstein, F. 1992. Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1. J. Biol. Chem. 267:1904-1909.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 1904-1909
-
-
Heidenreich, O.1
Eckstein, F.2
-
38
-
-
0027435063
-
Importance of independence in ribozyme reactions: Kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus
-
Ohkawa, J., Yuyama, N., Takebe, Y, Nishikawa, S., and Taira, K. 1993. Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 90:11302-11306.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11302-11306
-
-
Ohkawa, J.1
Yuyama, N.2
Takebe, Y.3
Nishikawa, S.4
Taira, K.5
-
39
-
-
0018077590
-
Crystal structure of yeast phenylalanine transfer RNA
-
Sussman, J.L., Holbrook, S.R., Warrant, R.W., Church, G.M., and Kim, S.H. 1978. Crystal structure of yeast phenylalanine transfer RNA. I. crystallographic refinement. J. Mol. Biol. 123:607-630.
-
(1978)
I. Crystallographic Refinement. J. Mol. Biol
, vol.123
, pp. 607-630
-
-
Sussman, J.L.1
Holbrook, S.R.2
Warrant, R.W.3
Church, G.M.4
Kim, S.H.5
-
40
-
-
0028863805
-
In vitro activity of minimized hammerhead ribozymes
-
Hendry, P., McCall, M.J., Santiago, F.S., and Jennings, PA. 1995. In vitro activity of minimized hammerhead ribozymes. Nucleic Acids Res. 23:3922-3927.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3922-3927
-
-
Hendry, P.1
McCall, M.J.2
Santiago, F.S.3
Jennings, P.A.4
-
41
-
-
0028834246
-
Structural studies of DNA three-way junctions
-
Leontis, N.B., Piotto, M.E., Hills, M.T., Malhotra, A., Ouporov, I.V., Nussbaum, J.N. et al. 1995. Structural studies of DNA three-way junctions. Methods Enzymol. 261:183-207.
-
(1995)
Methods Enzymol
, vol.261
, pp. 183-207
-
-
Leontis, N.B.1
Piotto, M.E.2
Hills, M.T.3
Malhotra, A.4
Ouporov, I.V.5
Nussbaum, J.N.6
-
42
-
-
0032580454
-
A simple assay system for examination of the inhibitory potential in vivo of decoy RNAs, ribozymes and other drugs by measuring the Tat-mediated transcription of fusion gene composed of the long terminal repeat of HIV-1 and a gene for luciferase
-
Koseki, S., Ohkawa, J., Yamamoto, R., Takebe, Y, and Taira, K. 1998. A simple assay system for examination of the inhibitory potential in vivo of decoy RNAs, ribozymes and other drugs by measuring the Tat-mediated transcription of fusion gene composed of the long terminal repeat of HIV-1 and a gene for luciferase. J. Controlled Release 53:159-173.
-
(1998)
J. Controlled Release
, vol.53
, pp. 159-173
-
-
Koseki, S.1
Ohkawa, J.2
Yamamoto, R.3
Takebe, Y.4
Taira, K.5
|