Theoretical design of antisense RNA structures substantially improves annealing kinetics and efficacy in human cells

Nature Biotechnology

Volumn 16, Issue 1, 1998, Pages 64-68

  Patzel, Volker ^a   Sczakiel, Georg ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

RNA mapping; RNA RNA hybridization; Structure function

Indexed keywords

COMPLEMENTARY RNA;

ARTICLE; CELL ADHESION; CELL KINETICS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; RNA STRUCTURE; THERMODYNAMICS; VIRUS INHIBITION;

ANIMALS; BINDING, COMPETITIVE; COMPUTER SIMULATION; DRUG DESIGN; HIV-1; HUMANS; KINETICS; RNA, ANTISENSE; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES; TRANSFECTION; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0031963785     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0198-64     Document Type: Article

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