메뉴 건너뛰기




Volumn 4, Issue 4, 2002, Pages 101-110

Role of genetic and expression profiling in pharmacogenomics: The changing face of patient management

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CODEINE; CYTOCHROME P450 2D6; DEBRISOQUINE; FLUOROURACIL; GEMCITABINE; IRINOTECAN; ISONIAZID; MERCAPTOPURINE; METHOTREXATE; MONOCLONAL ANTIBODY; MORPHINE; NORTRIPTYLINE; ONYX 015; RECOMBINANT PROTEIN; TAMOXIFEN; THIOPURINE METHYLTRANSFERASE; TIOGUANINE; TRASTUZUMAB; WARFARIN; ANTINEOPLASTIC ANTIMETABOLITE;

EID: 0036808725     PISSN: 14673037     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (83)
  • 1
    • 0030682522 scopus 로고    scopus 로고
    • The cost of adverse drug reactions
    • Editorial
    • Editorial. 1997. The cost of adverse drug reactions. Adverse Drug React. Toxicol. Rev. 16: 75-78.
    • (1997) Adverse Drug React. Toxicol. Rev , vol.16 , pp. 75-78
  • 4
    • 0032924895 scopus 로고    scopus 로고
    • The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis
    • Banks, R.E. Dunn, MJ. Forbes, M.A. Stanley, A. Pappin, D. Naven, T. Gough, M. Harnden, P., and Selby P.J. 2000. The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis. Electrophoresis. 20: 689-700.
    • (2000) Electrophoresis , vol.20 , pp. 689-700
    • Banks, R.E.1    Dunn, M.J.2    Forbes, M.A.3    Stanley, A.4    Pappin, D.5    Naven, T.6    Gough, M.7    Harnden, P.8    Selby, P.J.9
  • 5
    • 0011280852 scopus 로고    scopus 로고
    • The pharma frenzy: In the race for gene-based therapies, big drug-makers join forces with upstarts
    • June
    • Barrett, A. 2000. The pharma frenzy: in the race for gene-based therapies, big drug-makers join forces with upstarts. Business Week June: 160-161.
    • (2000) Business Week , pp. 160-161
    • Barrett, A.1
  • 8
    • 0035201633 scopus 로고    scopus 로고
    • The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders
    • Bowater, R.P., and Wells, R.D. 2001. The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders. Prog. Nucleic Acid Res. Mol. Biol. 66: 159-202.
    • (2001) Prog. Nucleic Acid Res. Mol. Biol , vol.66 , pp. 159-202
    • Bowater, R.P.1    Wells, R.D.2
  • 9
    • 0034969758 scopus 로고    scopus 로고
    • Use of surface-enhanced laser desorption ionization protein chip system to analyze streptococcal exotoxin B activity secreted by Streptococcus pyogenes
    • Boyle, M.D. Romer, T.G. Meeker, A. K., and Sledjeski, D. D. 2001. Use of surface-enhanced laser desorption ionization protein chip system to analyze streptococcal exotoxin B activity secreted by Streptococcus pyogenes. J. Microbiol. Methods. 46:87-97.
    • (2001) J. Microbiol. Methods , vol.46 , pp. 87-97
    • Boyle, M.D.1    Romer, T.G.2    Meeker, A.K.3    Sledjeski, D.D.4
  • 10
    • 0025950370 scopus 로고
    • Debrisoquine/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in European population
    • Broly, F. Gaedigk, A. Heim, M. Eichelbaum, M. Morike, K., and Meyer, U.A. 1991. Debrisoquine/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in European population. DNA Cell. Biol. 10: 545-558.
    • (1991) DNA Cell. Biol , vol.10 , pp. 545-558
    • Broly, F.1    Gaedigk, A.2    Heim, M.3    Eichelbaum, M.4    Morike, K.5    Meyer, U.A.6
  • 11
    • 84984932472 scopus 로고    scopus 로고
    • Exploring the new world of the genome with DNA microarrays
    • Brown, P.O., and Botstein, D. 1999. Exploring the new world of the genome with DNA microarrays. Nature Genet. 21: 33-7.
    • (1999) Nature Genet , vol.21 , pp. 33-37
    • Brown, P.O.1    Botstein, D.2
  • 12
    • 0034164631 scopus 로고    scopus 로고
    • Signal amplification through nucleotide extension and excision on a dendritic DNA platform
    • Capaldi, S. Getts, R.C., and Jayasena, S.D. 2000. Signal amplification through nucleotide extension and excision on a dendritic DNA platform. Nucleic Acids Res. 28: E21.
    • (2000) Nucleic Acids Res , vol.28
    • Capaldi, S.1    Getts, R.C.2    Jayasena, S.D.3
  • 13
    • 0032856945 scopus 로고    scopus 로고
    • Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay
    • Carson, R.T., and Vignali, D.A. 1999. Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay. J. Immunol. Methods. 227: 41-52.
    • (1999) J. Immunol. Methods , vol.227 , pp. 41-52
    • Carson, R.T.1    Vignali, D.A.2
  • 14
    • 0034468690 scopus 로고    scopus 로고
    • A functional complex of adeno-virus proteins E1B-55kDa and E4orf6 is necessary to modulate the expression level of p53 but not its transcriptional activity
    • Cathomen, T., and Weitzman, MD. 2000. A functional complex of adeno-virus proteins E1B-55kDa and E4orf6 is necessary to modulate the expression level of p53 but not its transcriptional activity. J. Virol. 74: 11407-11412.
    • (2000) J. Virol , vol.74 , pp. 11407-11412
    • Cathomen, T.1    Weitzman, M.D.2
  • 15
    • 0031889106 scopus 로고    scopus 로고
    • Microchip systems for immunoassay: An integrated immunoreactor with electrophoretic separation for serum theophylline determination
    • Chiem, N.H., and Harrison, D.J. 1998. Microchip systems for immunoassay: an integrated immunoreactor with electrophoretic separation for serum theophylline determination. Clin. Chem. 44: 591-598.
    • (1998) Clin. Chem , vol.44 , pp. 591-598
    • Chiem, N.H.1    Harrison, D.J.2
  • 16
    • 0035895513 scopus 로고    scopus 로고
    • What if there are only 30,000 human genes?
    • Claverie, J.M. 2001. What if there are only 30,000 human genes? Science. 291: 1255-7.
    • (2001) Science , vol.291 , pp. 1255-1257
    • Claverie, J.M.1
  • 18
    • 0033973925 scopus 로고    scopus 로고
    • Pharmacogenetic methods as a complement to therapeutic monitoring of antidepressants and neuroleptics
    • Dahl, M.L., and Sjoqvist, F. 2000. Pharmacogenetic methods as a complement to therapeutic monitoring of antidepressants and neuroleptics. Ther. Drug. Monit. 22: 114-117.
    • (2000) Ther. Drug. Monit , vol.22 , pp. 114-117
    • Dahl, M.L.1    Sjoqvist, F.2
  • 19
    • 0026610576 scopus 로고
    • Analysis of the CYP2D6 gene in relation to debrisoquine and desipramine hydroxylation in a Swedish population
    • Dahl, M.L. Johansson, I. Porsmyr Palmertz, M. Ingelman-Sundberg, M., and Sjoqvist, F. 1992. Analysis of the CYP2D6 gene in relation to debrisoquine and desipramine hydroxylation in a Swedish population. Clin. Pharmacol. Ther. 51: 12-17.
    • (1992) Clin. Pharmacol. Ther , vol.51 , pp. 12-17
    • Dahl, M.L.1    Johansson, I.2    Porsmyr Palmertz, M.3    Ingelman-Sundberg, M.4    Sjoqvist, F.5
  • 20
    • 0034564420 scopus 로고    scopus 로고
    • The protein chip system from Ciphergen: A new technique for rapid, micro-scale protein biology
    • Davies, H.A. 2000. The protein chip system from Ciphergen: a new technique for rapid, micro-scale protein biology. J. Mol. Med. 78: B29.
    • (2000) J. Mol. Med , vol.78
    • Davies, H.A.1
  • 21
    • 0032833671 scopus 로고    scopus 로고
    • Genomic amplification of the human DHFR/MSH3 locus remodels mismatch recognition and repair activities
    • Drummond, J.T 1999. Genomic amplification of the human DHFR/MSH3 locus remodels mismatch recognition and repair activities. Adv. Enz. Regul. 39: 129-41.
    • (1999) Adv. Enz. Regul , vol.39 , pp. 129-141
    • Drummond, J.T.1
  • 22
    • 0034880019 scopus 로고    scopus 로고
    • The effect of antisense Bcl-2 oligonucleotides on Bcl-2 protein expression and apoptosis in human bladder transitional cell carcinoma
    • Duggan, B.J. Maxwell, P. Kelly, J.D. Canning, P., anderson, N.H. Keane, P.F. Johnston, S.R., and Williamson, K.E. 2001. The effect of antisense Bcl-2 oligonucleotides on Bcl-2 protein expression and apoptosis in human bladder transitional cell carcinoma. J. Urol. 166: 1098-105.
    • (2001) J. Urol , vol.166 , pp. 1098-1105
    • Duggan, B.J.1    Maxwell, P.2    Kelly, J.D.3    Canning, P.4    Anderson, N.H.5    Keane, P.F.6    Johnston, S.R.7    Williamson, K.E.8
  • 23
    • 0026347009 scopus 로고
    • Multianalyte microspot immunoassay-microanalytical 'compact disk'of the future
    • Ekins, R., and Chu, F.W. 1991. Multianalyte microspot immunoassay-microanalytical 'compact disk'of the future. Clin. Chem. 37:1955-1967.
    • (1991) Clin. Chem , vol.37 , pp. 1955-1967
    • Ekins, R.1    Chu, F.W.2
  • 24
    • 0003076974 scopus 로고    scopus 로고
    • 2nd Edn, Eds Price, C. P., and Newman, D. J. Stockton, New York
    • Ekins, R., and Chu, R.W. 1997. In: Principals and Practices of Immunoassays 2nd Edn, Eds Price, C. P., and Newman, D. J. Stockton, New York.p. 625-646.
    • (1997) Principals and Practices of Immunoassays , pp. 625-646
    • Ekins, R.1    Chu, R.W.2
  • 25
    • 0033031592 scopus 로고    scopus 로고
    • Microarrays: Their origins and applications
    • Ekins, R., and Chu, F.W. 1999. Microarrays: their origins and applications. Trends. Biotechnol. 17: 217-218.
    • (1999) Trends. Biotechnol , vol.17 , pp. 217-218
    • Ekins, R.1    Chu, F.W.2
  • 27
    • 26444539817 scopus 로고
    • Genetic control of isoniazid metabolism in man
    • Evans, D.A.P. Manley, K.A., and McKusick, V.A. 1960. Genetic control of isoniazid metabolism in man. Br. Med. J.2:485-491.
    • (1960) Br. Med. J , vol.2 , pp. 485-491
    • Evans, D.A.P.1    Manley, K.A.2    McKusick, V.A.3
  • 28
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans, W.E., and Relling, M.V. 1999. Pharmacogenomics: translating functional genomics into rational therapeutics. Science. 286: 487-491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 29
    • 0347324278 scopus 로고    scopus 로고
    • Screening technologies evolve: Innovations spurred by race to profit from genetic data
    • Flanagan, A. 2000. Screening technologies evolve: innovations spurred by race to profit from genetic data. Genet. Eng. News. 20: 19-20.
    • (2000) Genet. Eng. News , vol.20 , pp. 19-20
    • Flanagan, A.1
  • 32
    • 0011322888 scopus 로고    scopus 로고
    • Technologies for the analysis of single-nucleotide polymorphisms: An overview
    • Eds. Kalow, Meyer and Tyndale. Published by Marcel Dekker, Inc. New York
    • Grant, D.M., and Phillips, M.S. 2001. Technologies for the analysis of single-nucleotide polymorphisms: an overview. In: Pharmacogenomics. Eds. Kalow, Meyer and Tyndale. Published by Marcel Dekker, Inc. New York, volume 113, pages 183-190.
    • (2001) Pharmacogenomics , vol.113 , pp. 183-190
    • Grant, D.M.1    Phillips, M.S.2
  • 34
    • 0032875697 scopus 로고    scopus 로고
    • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    • Gygi, S.P. Rist, B. Gerber, S.A. Turecek, F. Gelb, M.H., and Aebersold, R. 1999. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nature Biotechnol. 17: 994-999.
    • (1999) Nature Biotechnol , vol.17 , pp. 994-999
    • Gygi, S.P.1    Rist, B.2    Gerber, S.A.3    Turecek, F.4    Gelb, M.H.5    Aebersold, R.6
  • 35
    • 0029829670 scopus 로고    scopus 로고
    • Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis
    • Hacia, J.G. Brody, L.C. Chee, M.S. Fodor, S.P., and Collins, F.S. 1996. Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis. Nature Genet. 14: 441-7.
    • (1996) Nature Genet , vol.14 , pp. 441-447
    • Hacia, J.G.1    Brody, L.C.2    Chee, M.S.3    Fodor, S.P.4    Collins, F.S.5
  • 37
    • 0025080352 scopus 로고
    • Genotyping of poor metabolizers of debrisoquine by allele specific PCR amplification
    • Heim, M.H., and Meyer, U.A. 1990. Genotyping of poor metabolizers of debrisoquine by allele specific PCR amplification. Lancet. 336: 529-532.
    • (1990) Lancet , vol.336 , pp. 529-532
    • Heim, M.H.1    Meyer, U.A.2
  • 38
    • 0030751010 scopus 로고    scopus 로고
    • Proteome research: Complementarity and limitations with respect to the RNA and DNA worlds
    • Humphery-Smith, I. Cordwell, S.J., and Blackstock, W.P. 1997. Proteome research: Complementarity and limitations with respect to the RNA and DNA worlds. Electrophoresis. 18: 1217-1242.
    • (1997) Electrophoresis , vol.18 , pp. 1217-1242
    • Humphery-Smith, I.1    Cordwell, S.J.2    Blackstock, W.P.3
  • 39
    • 0035289301 scopus 로고    scopus 로고
    • Determinants of prognosis and response to therapy in colorectal cancer
    • Iqbal, S., and Lenz, H.J. 2001. Determinants of prognosis and response to therapy in colorectal cancer. Curr. Oncol. Reports. 3: 102-108
    • (2001) Curr. Oncol. Reports , vol.3 , pp. 102-108
    • Iqbal, S.1    Lenz, H.J.2
  • 40
    • 0032519431 scopus 로고    scopus 로고
    • Genetic predisposition to the metabolism of irinotecan: Role of UGT1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
    • Iyer, L. King, C.D. Whitington, P.F. Roy, S.K. Green, M.D. Tephly, TR. Coffman, B.L., and Ratain, M.J. 1998. Genetic predisposition to the metabolism of irinotecan: role of UGT1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J. Clin. Invest. 101: 847-854.
    • (1998) J. Clin. Invest , vol.101 , pp. 847-854
    • Iyer, L.1    King, C.D.2    Whitington, P.F.3    Roy, S.K.4    Green, M.D.5    Tephly, T.R.6    Coffman, B.L.7    Ratain, M.J.8
  • 41
    • 0028940399 scopus 로고
    • Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
    • Johnston, P. Lenz, H.J. Leichman, C.G. Danenberg, K.D. Allegra, C.J. Danenberg, P.V., and Leichman, L. 1995. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer. Res. 55: 1407-1412.
    • (1995) Cancer Res , vol.55 , pp. 1407-1412
    • Johnston, P.1    Lenz, H.J.2    Leichman, C.G.3    Danenberg, K.D.4    Allegra, C.J.5    Danenberg, P.V.6    Leichman, L.7
  • 42
    • 0032040253 scopus 로고    scopus 로고
    • Microminiaturized immunoassays using atomic force microscopy and compositionally patterned antigen arrays
    • Jones, V.W. Kenseth, J.R. Porter, M.D. Mosher, C.L., and Henderson, E. 1998. Microminiaturized immunoassays using atomic force microscopy and compositionally patterned antigen arrays. Anal. Chem. 70: 1233-1241.
    • (1998) Anal. Chem , vol.70 , pp. 1233-1241
    • Jones, V.W.1    Kenseth, J.R.2    Porter, M.D.3    Mosher, C.L.4    Henderson, E.5
  • 43
    • 0035061867 scopus 로고    scopus 로고
    • Tissue microarray technology for high-throughput molecular profiling of cancer
    • Kallioniemi, O.P. Wagner, U. Kononen, J., and Sauter, G. 2001. Tissue microarray technology for high-throughput molecular profiling of cancer. Human Molecular Genetics. 10: 657-62.
    • (2001) Human Molecular Genetics , vol.10 , pp. 657-662
    • Kallioniemi, O.P.1    Wagner, U.2    Kononen, J.3    Sauter, G.4
  • 44
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • Lazarou, J. Pomeranz, B.H., and Corey, P.N. 1998. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. J. A. M. A. 279: 1200-1205.
    • (1998) J. A. M. A , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 45
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted infusion fluorouracil and weekly leucovorin
    • Leichman, C.G. Lenz, H.J. Danenberg, K.D. Leichman, L. Danenberg, K.D. Baranda, J. Groshen, S. Boswell, W. Metzger, R. Tan, M., and Danenberg, P.V. 1997. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted infusion fluorouracil and weekly leucovorin. J. Clin. Oncol. 15: 3223-3229.
    • (1997) J. Clin. Oncol , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Danenberg, K.D.3    Leichman, L.4    Danenberg, K.D.5    Baranda, J.6    Groshen, S.7    Boswell, W.8    Metzger, R.9    Tan, M.10    Danenberg, P.V.11
  • 47
    • 0026674886 scopus 로고
    • Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
    • Liang, P., and Pardee, A.B. 1992. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 257: 967-971.
    • (1992) Science , vol.257 , pp. 967-971
    • Liang, P.1    Pardee, A.B.2
  • 51
    • 0034622925 scopus 로고    scopus 로고
    • Printing Proteins as Microarrays for High-Throughput Function Determination
    • MacBeath, G., and Schreiber, S. L. 2000 Printing Proteins as Microarrays for High-Throughput Function Determination. Science. 289: 1760-1763.
    • (2000) Science , vol.289 , pp. 1760-1763
    • MacBeath, G.1    Schreiber, S.L.2
  • 54
    • 0034638766 scopus 로고    scopus 로고
    • Pharmacogenetics and adverse drug reactions
    • Meyer, U.A. 2000. Pharmacogenetics and adverse drug reactions. Lancet 356, 1667-1671.
    • (2000) Lancet , vol.356 , pp. 1667-1671
    • Meyer, U.A.1
  • 55
    • 0035027648 scopus 로고    scopus 로고
    • A novel method for detecting HIV-1 by non-radioactive in situ hybridization: Application of a peptide nucleic acid probe and catalysed signal amplification
    • Murakami, T Hagiwara, T. Yamamoto, K. Hattori, J. Kasami, M. Utsumi, M., and Kaneda, T. 2001. A novel method for detecting HIV-1 by non-radioactive in situ hybridization: application of a peptide nucleic acid probe and catalysed signal amplification. J. Pathol. 194: 130-5.
    • (2001) J. Pathol , vol.194 , pp. 130-135
    • Murakami, T.1    Hagiwara, T.2    Yamamoto, K.3    Hattori, J.4    Kasami, M.5    Utsumi, M.6    Kaneda, T.7
  • 56
    • 0031974212 scopus 로고    scopus 로고
    • Multianalyte detection using a capillary-based flow immunosensor
    • Narang, U. Gauger, P.R. Kusterbeck, A.W., and Ligler, F.S. 1998. Multianalyte detection using a capillary-based flow immunosensor. Anal. Biochem. 255: 13-19.
    • (1998) Anal. Biochem , vol.255 , pp. 13-19
    • Narang, U.1    Gauger, P.R.2    Kusterbeck, A.W.3    Ligler, F.S.4
  • 57
    • 0011370830 scopus 로고    scopus 로고
    • Adverse drug reactions: Harnessing experiential data to promote patient welfare
    • Noah, B.A. 2000. Adverse drug reactions: harnessing experiential data to promote patient welfare. Catholic U. Law Rev. 49: 449-504.
    • (2000) Catholic U. Law Rev , vol.49 , pp. 449-504
    • Noah, B.A.1
  • 59
    • 0034063779 scopus 로고    scopus 로고
    • (SELDI) Biomarker profiling of stages of cancer progression directly from human tissue using a protein biochip
    • Paweletz, C.P. 2000. (SELDI) Biomarker profiling of stages of cancer progression directly from human tissue using a protein biochip. Drug Develop. Res. 49: 34-42.
    • (2000) Drug Develop. Res , vol.49 , pp. 34-42
    • Paweletz, C.P.1
  • 61
    • 0033651234 scopus 로고    scopus 로고
    • The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer
    • Pegram, M.D. Konecny, G., and Slamon, D.J. 2000. The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer. Cancer Treatment and Research. 103: 57-75.
    • (2000) Cancer Treatment and Research , vol.103 , pp. 57-75
    • Pegram, M.D.1    Konecny, G.2    Slamon, D.J.3
  • 62
    • 0035054387 scopus 로고    scopus 로고
    • Deficient DNA mismatch repair: A common etiologic factor for colon cancer. Deficient DNA mismatch repair: A common etiologic factor for colon cancer
    • Peltomaki, P. 2001. Deficient DNA mismatch repair: a common etiologic factor for colon cancer. Deficient DNA mismatch repair: a common etiologic factor for colon cancer. Hum. Mol. Genet. 10: 735-40.
    • (2001) Hum. Mol. Genet , vol.10 , pp. 735-740
    • Peltomaki, P.1
  • 63
  • 64
    • 0035884143 scopus 로고    scopus 로고
    • High-resolution and high-throughput protocols for measuring drug/human serum albumin interactions using BIACORE
    • Rich, R.L. Day, Y.S. Morton, T.A., and Myszka, D.G. 2001. High-resolution and high-throughput protocols for measuring drug/human serum albumin interactions using BIACORE. Anal Biochem. 296:197-207.
    • (2001) Anal Biochem , vol.296 , pp. 197-207
    • Rich, R.L.1    Day, Y.S.2    Morton, T.A.3    Myszka, D.G.4
  • 65
    • 0003606153 scopus 로고
    • PCR: Clinical diagnostics and research
    • Springer-Verlag, Berlin
    • Rolfs, A. Schuller, I. Finckh, U., and Weber-Rolfs, I. 1992. PCR: Clinical diagnostics and research. Springer-Verlag, Berlin. p. 1-271.
    • (1992) , pp. 1-271
    • Rolfs, A.1    Schuller, I.2    Finckh, U.3    Weber-Rolfs, I.4
  • 66
    • 0032533513 scopus 로고    scopus 로고
    • Comparative genomic hybridization analysis of chromosomal alterations induced by the development of resistance to thymidylate synthase inhibitors
    • Rooney, P.H. Stevenson, D.A. Marsh, S. Johnston, P.G. Haites, N.E. Cassidy, J., and McLeod, H.L. 1998. Comparative genomic hybridization analysis of chromosomal alterations induced by the development of resistance to thymidylate synthase inhibitors. Cancer Res. 58: 5042-5045.
    • (1998) Cancer Res , vol.58 , pp. 5042-5045
    • Rooney, P.H.1    Stevenson, D.A.2    Marsh, S.3    Johnston, P.G.4    Haites, N.E.5    Cassidy, J.6    McLeod, H.L.7
  • 67
    • 0032148838 scopus 로고    scopus 로고
    • Genetic privacy and confidentiality: Why they are so hard to protect
    • Rothstein, M.A. 1998 Genetic privacy and confidentiality: why they are so hard to protect. J. Law Med. Ethics 26: 198-204.
    • (1998) J. Law Med. Ethics , vol.26 , pp. 198-204
    • Rothstein, M.A.1
  • 70
    • 0027560888 scopus 로고
    • A fiber optic evanescent-wave immunosensor for large molecules
    • Shriver-Lake, L.C. Ogert, R.A., and Ligler, F.S. 1993. A fiber optic evanescent-wave immunosensor for large molecules. Sensors Actuators. 11: 239-243.
    • (1993) Sensors Actuators , vol.11 , pp. 239-243
    • Shriver-Lake, L.C.1    Ogert, R.A.2    Ligler, F.S.3
  • 71
    • 0031751340 scopus 로고    scopus 로고
    • Mass-sensing multianalyte microarray immunoassay with imaging detection
    • Silzel, J.W. Cercek, B. Dodson, C. Tsay, T., and Obremski, R.J. 1998. Mass-sensing multianalyte microarray immunoassay with imaging detection. Clin. Chem. 44: 2036-2043.
    • (1998) Clin. Chem , vol.44 , pp. 2036-2043
    • Silzel, J.W.1    Cercek, B.2    Dodson, C.3    Tsay, T.4    Obremski, R.J.5
  • 72
    • 0016700864 scopus 로고
    • Detection of specific sequences among DNA fragments separated by gel electrophoresis
    • Southern, E.M. 1975. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98: 503-17.
    • (1975) J. Mol. Biol , vol.98 , pp. 503-517
    • Southern, E.M.1
  • 74
    • 0035865087 scopus 로고    scopus 로고
    • A physical map of the human genome
    • The international human genome mapping consortium
    • The international human genome mapping consortium. 2001. A physical map of the human genome. Nature. 409, 934-941.
    • (2001) Nature , vol.409 , pp. 934-941
  • 76
    • 0034114654 scopus 로고    scopus 로고
    • Downstream molecular determinants of response to 5 fluorouracil and antifolate thymidylate synthase inhibition
    • Van Triest, B. Pinedo, H.M. Giaccone, G., and Peters, G.J. 2000. Downstream molecular determinants of response to 5 fluorouracil and antifolate thymidylate synthase inhibition. Annals Oncol. 11:385-391.
    • (2000) Annals Oncol , vol.11 , pp. 385-391
    • Van Triest, B.1    Pinedo, H.M.2    Giaccone, G.3    Peters, G.J.4
  • 79
    • 0032030297 scopus 로고    scopus 로고
    • Biosensors and bioelectronics: Detection of multiple toxic agents using a planar array
    • Wadkins, R.M. 1998. Biosensors and bioelectronics: detection of multiple toxic agents using a planar array. Immunosensor. 13: 407-415.
    • (1998) Immunosensor , vol.13 , pp. 407-415
    • Wadkins, R.M.1
  • 80
    • 0035056404 scopus 로고    scopus 로고
    • Thiopurine pharmacogenetics: Clinical and molecular studies of thiopurine methyl transferase
    • Weinshilboum, R. 2001. Thiopurine pharmacogenetics: clinical and molecular studies of thiopurine methyl transferase. Drug Metabolism and Dispos. 29: 601-605.
    • (2001) Drug Metabolism and Dispos , vol.29 , pp. 601-605
    • Weinshilboum, R.1
  • 82
    • 0034621009 scopus 로고    scopus 로고
    • Science, medicine and the future: Pharmacogenetics
    • Wolf, C.R. Smith, G., and Smith, R.L. 2000. Science, medicine and the future: pharmacogenetics. Brit. Med. J. 320: 987-990.
    • (2000) Brit. Med. J , vol.320 , pp. 987-990
    • Wolf, C.R.1    Smith, G.2    Smith, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.