The KH domains of Xenopus Vg1RBP mediate RNA binding and self-association

RNA

Volumn 8, Issue 10, 2002, Pages 1319-1333

  Git, Anna ^a   Standart, Nancy ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

3 untranslated region; Maternal mRNA; RNA localization; RRM; Vegetal cortex

Indexed keywords

BINDING PROTEIN; MESSENGER RNA; PROTEIN VG1RBP; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; COMPLEX FORMATION; GENE LOCATION; GENE TARGETING; MICROTUBULE; OOCYTE DEVELOPMENT; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; RNA SEQUENCE; RNA STABILITY; SEQUENCE HOMOLOGY; XENOPUS;

3' UNTRANSLATED REGIONS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELLS, CULTURED; FEMALE; GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; OOCYTES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFORMING GROWTH FACTOR BETA; XENOPUS; XENOPUS PROTEINS;

EID: 0036792844     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S135583820202705X     Document Type: Article

References (50)

1. Adinolfi S, Bagni C, Castiglione Morelli MA, Fraternali F, Musco G, Pastore A. 1999. Novel RNA-binding motif: The KH module. Biopolymers 51:153-164.
2. Black DL, Chan R, Min H, Wang J, Bell L. 1998. The electrophoretic mobility shift assay for RNA binding proteins. In Smith CWJ, ed. RNA-protein interactions, a practical approach. Oxford: Oxford University Press.
3. Bubunenko M, Kress TL, Vempati UD, Mowry KL, King ML. 2002. A consensus RNA signal that directs germ layer determinants to the vegetal cortex of Xenopus oocytes. Dev Biol 248:82-92.
4. Chen T, Damaj BB, Herrera C, Lasko P, Richard S. 1997. Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: Role of the KH domain. Mol Cell Biol 17:5707-5718.
5. Chen T, Richard S. 1998. Structure function analysis of Qk1: A lethal point mutation in mouse quaking prevents homodimerization. Mol Cell Biol 18:4863-4871.
6. Conte MR, Grune T, Gluman J, Kelly G, Ladas A, Matthews S, Curry S. 2000. Structure of tandem RNA recognition motifs from polypyrimidine tract binding protein reveals novel features of the RRM fold. EMBO J 19:3132-3141.
7. Cote CA, Gautreau D, Denegre JM, Kress TL, Terry NA, Mowry KL. 1999. A Xenopus protein related to hnRNP I has a role in cytoplasmic RNA localization. Mol Cell 4:431-437.
8. Darnell JC, Jensen KB, Jin P, Brown V, Warren ST, Darnell RB. 2001. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell 107:489-499.
9. Dasso MC, Jackson RJ. 1989. On the fidelity of mRNA translation in the nuclease-treated rabbit reticulocyte lysate system. Nucleic Acids Res 17:3129-3144.
10. Deshler JO, Highett MI, Abramson T, Schnapp BJ. 1998. A highly conserved RNA-binding protein for cytoplasmic mRNA localization in vertebrates. Curr Biol 8:489-496.
11. Deshler JO, Highett MI, Schnapp BJ. 1997. Localization of Xenopus Vg1 mRNA by Vera protein and the endoplasmic reticulum. Science 276:1128-1131.
12. Doyle GA, Betz NA, Leeds PF, Fleisig AJ, Prokipcak RD, Ross J. 1998. The c-myc coding region determinant-binding protein: A member of a family of KH domain RNA-binding proteins. Nucleic Acids Res 26:5036-5044.
13. Elisha Z, Havin L, Ringel I, Yisraeli J. 1995. Vg1 RNA binding protein mediates the association of Vg1 RNA with microtubules in Xenopus oocytes. EMBO J 14:5109-5114.
14. Grishin NV. 2001. KH domain: One motif, two folds. Nucleic Acids Res 29:638-643.
15. Harvey I, Garneau P, Pelletier J. 2002. Forced engagement of a RNA-protein complex by a chemical inducer of dimerization to modulate gene expression. Proc Natl Acad Sci USA 99:1882-1887.
16. Havin L, Git A, Elisha Z, Oberman F, Schwartz SP, Standart N, Yisraeli JK. 1998. RNA binding protein conserved in both microtubule and microfilament-based RNA localization. Genes & Dev 12:1593-1598.
17. Jackson RJ, Hunt T. 1983. Preparation and use of nuclease treated rabbit reticulocyte lysate for the translation of eukaryotic mRNAs. Methods in Enzymol 96:50-72.
18. Kessler SH, Sachs AB. 1998. RNA recognition motif 2 of yeast Pab1p is required for its functional interaction with eukaryotic translation initiation factor 4G. Mol Cell Biol 18:51-57.
19. Kim JH, Hahm B, Kim YK, Choi M, Jang SK. 2000. Protein-protein interaction among hnRNPs shuttling between nucleus and cytoplasm. J Mol Biol 298:395-405.
20. King ML, Zhou Y, Bubunenko M. 1999. Polarizing genetic information in the egg: RNA localization in the frog oocyte. BioEssays 21:546-557.
21. Kloc M, Zearfoss NR, Etkin LD. 2002. Mechanisms of subcellular RNA localization. Cell 108:533-544.
22. Kwon S, Abramson T, Munro TP, John CM, Kohrmann M, Schnapp BJ. 2002. UUCAC and Vera dependent localization of VegT RNA in Xenopus oocytes. Curr Biol 12:558-564
23. Lewis HA, Chen H, Edo C, Buckanovich RJ, Yang YY, Musunuru K, Zhong R, Darnell RB, Burley SK. 1999. Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. Structure Fold Des 7:191-203.
24. Lewis HA, Musunuru K, Jansen KB, Edo C, Chen H, Darnell RB, Burley SK. 2000. Sequence-specific RNA binding by a Nova KH domain: Implications for paraneoplastic disease and the fragile X syndrome. Cell 100:323-332.
25. Mowry K. 1996. Complex formation between stage-specific oocyte factors and a Xenopus mRNA localization element. Proc Natl Acad Sci USA 93:14608-14613.
26. Mowry KL, Melton DA. 1992. Vegetal messenger RNA localization directed by a 340-nt RNA sequence element in Xenopus oocytes. Science 255:991-994.
27. Müeller-Pillasch F, Lacher U, Wallrapp C, Micha A, Zimmerhackl F, Hameister H, Varga G, Friess H, Büchler M, Beger HG, Vila MR, Adler G, Gress TM. 1997. Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein. Oncogene 14:2729-2733.
28. Nielsen FC, Nielsen J, Kristensen MA, Koch G, Christiansen J. 2002. Cytoplasmic trafficking of IGF-II mRNA-binding proteins by conserved KH domains. J Cell Sci 115:2087-2097.
29. Nielsen J, Christiansen J, Lykke-Andersen J, Johnsen AH, Wewer UM, Nielsen FC. 1999. A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development. Mol Cell Biol 9:1262-1270.
30. Nielsen J, Nielsen FC, Jakobsen RK, Christiansen J. 2000. The biphasic expression of IMP/Vg1-RBP is conserved between vertebrates and Drosophila. Mech Dev 96:129-132.
31. Otero LJ, Ashe MP, Sachs AB. 1999. The yeast poly(A)-binding protein Pab1p stimulates in vitro poly (A)-dependent and capdependent translation by distinct mechanisms. EMBO J 18:3153-3163.
32. Otero LJ, Devaux A, Standart N. 2001. A 250-nucleotide UA-rich element in the 3′ untranslated region of Xenopus laevis Vg 1 mRNA represses translation both in vivo and in vitro. RNA 7:1-15.
33. Palacios IM, St Johnston D. 2001. Getting the message across: The intracellular localization of mRNAs in higher eukaryotes. Annu Rev Cell Dev Biol 17:569-614.
34. Perez I, McAfee JG, Patton JG. 1997. Multiple RRMs contribute to RNA binding specificity and affinity for polypyrimidine tract binding protein. Biochemistry 36:11881-11890.
35. Ramos A, Hollingworth D, Major SA, Adinolfi S, Kelly G, Muskett FW, Pastore A. 2002. Role of dimerization in KH/RNA complexes: The example of Nova KH3. Biochemistry 41:4193-201.
36. Ross AF, Oleynikov Y, Kislauskis EH, Taneja KL, Singer RH. 1997. Characterization of a β-actin mRNA zipcode-binding protein. Mol Cell Biol 17:2158-2165.
37. Samuels M, Deshpande G, Schedl P. 1998. Activities of the sex lethal protein in RNA binding and protein: protein interactions. Nucleic Acids Res 26:2625-2637.
38. Siomi H, Choi M, Siomi MC, Nussbaum RL, Dreyfuss G. 1994. Essential role for KH domains in RNA binding: Impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome. Cell 77:33-39.
39. Siomi M, Zhang Y, Siomi H, Dreyfuss G. 1996. Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them. Mol Cell Biol 16:3825-3832.
40. Thomas JO. 1989. Chemical cross-linking of histones. Methods Enzymol 170:549-571.
41. Varani G, Nagai K. 1998. RNA recognition by RNP proteins during RNA processing. Annu Rev Biophys Biomol Struct 27:407-445.
42. Walker J, Dale M, Standart N. 1996. Unmasking mRNA in clam oocytes: Role of phosphorylation of a 3′ UTR masking elementbinding protein at fertilization. Dev Biol 173:292-305.
43. Wilhelm J, Vale R, Hegde R. 2000. Coordinate control of translation and localization of Vg1 mRNA in Xenopus oocytes. Proc Natl Acad Sci USA 97:13132-13137.
44. Worbs M, Bourakev GP, Bartunik HD, Huber R, Wahl MC. 2001. An extended RNA binding surface through arrayed S1 and KH domains in transcription factor NusA. Mol Cell 7:1177-1189.
45. Yaniv K, Yisraeli JK. 2001. Defining cis-acting elements and transacting factors in RNA localization. Int Rev Cytol 203:521-539.
46. Yaniv K, Yisraeli JK. 2002. The involvement of a conserved family of RNA binding proteins in embryonic development and carcinogenesis. Gene 287:49-54.
47. Yisraeli JK, Sokol S, Melton DA. 1990. A two-step model for the localization of maternal mRNA in Xenopus oocytes: Involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA. Development 108:289-298.
48. Zhang HL, Eom T, Oleynikov Y, Shenoy SM, Liebelt DA, Dictenberg JB, Singer RH, Bassell GJ. 2001. Neurotrophin-induced transport of a β-actin mRNP complex increases β-actin levels and stimulates growth cone motility. Neuron 31:261-275.
49. Zhang Q, Yaniv K, Oberman F, Wolke U, Git A, Fromer M, Taylor WL, Meyer D, Standart N, Raz E, Yisraeli JK. 1999. Vg1 RBP intracellular distribution and evolutionarily conserved expression at multiple stages during development. Mech Dev 88:101-106.
50. Zhao WM, Jiang C, Kroll TT, Huber PW. 2001. A proline-rich protein binds to the localization element of Xenopus Vg1 mRNA and to ligands involved in actin polymerization. EMBO J 20:2315-2325.