Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: Role of the KH domain

Molecular and Cellular Biology

Volumn 17, Issue 10, 1997, Pages 5707-5718

  Chen, Taiping ^b,c   Damaj, Bassam B ^a,b,c   Herrera, Constance ^b,c   Lasko, Paul ^c   Richard, Stéphane ^b,c  

^a PHARMACOPEIA INC   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

RNA BINDING PROTEIN;

ANIMAL CELL; ARTEMIA; ARTICLE; CAENORHABDITIS ELEGANS; CELL STRAIN 3T3; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; SACCHAROMYCES CEREVISIAE;

ANIMALIA; ARTEMIA; ARTEMIA SALINA; CAENORHABDITIS ELEGANS; MAMMALIA; SACCHAROMYCES CEREVISIAE; SALINA;

EID: 0030879866     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.10.5707     Document Type: Article

References (47)

1. Arning, S., P. Gruter, G. Bilbe, and A. Kramer. 1996. Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA. RNA 2:794-810.
2. Ashley, C. T., K. D. Wilkinson, D. Reines, and S. T. Warren. 1993. FMR1 protein: conserved RNP family domains and selective RNA binding. Science 262:563-566.
3. Barlat, I., F. Maurier, M. Duchesne, E. Guitard, B. Tocque, and F. Schweighoffer. 1997. A role for Sam68 in cell cycle progression antagonized by a spliced variant within the KH domain. J. Biol. Chem. 272:3129-3132.
4. Bunnell, S. C., P. A. Henry, R. Kolluri, T. Kirchhausen, R. J. Rickles, and L. J. Berg. 1996. Identification of Itk/Tsk Src homology 3 domain ligands. J. Biol. Chem. 271:25646-25656.
5. Burd, C. G., and G. Dreyfuss. 1994. Conserved structures and diversity of functions of RNA-binding proteins. Science 265:615-621.
6. Cruz-Alvarez, M., and A. Pellicer. 1987. Cloning of a full-length complementary cDNA for a Artemia salina glycine-rich protein. J. Biol. Chem. 262:13377-13380.
7. DeBoulle, K., A. J. M. H. Verkerk, E. Reyniers, L. Vits, J. Hendrickx, B. V. Roy, F. V. D. Bos, E. DeGraaff, B. A. Oostra, and P. J. Willems. 1993. A point mutation in the FMR-1 gene associated with fragile X mental retardation. Nat. Genet. 3:31-35.
8. Durfee, T., K. Becherer, P. L. Chen, S. H. Yeh, Y. Yang, A. E. Kilburn, W. H. Lee, and S. J. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7:555-569.
9. Ebersole, T. A., Q. Chen, M. J. Justice, and K. Artzt. 1996. The quaking gene unites signal transduction and RNA binding in the developing nervous system. Nat. Genet. 12:260-265.
10. Evan, G. I., and J. M. Bishop. 1985. Isolation of monoclonal antibodies specific for the human c-myc protooncogene product. Mol. Cell. Biol. 4: 2843-2850.
11. Fields, S., and O. Song. 1989. A novel genetic system to detect protein-protein interactions. Nature 340:245-246.
12. Francis, R., M. K. Barton, J. Kimbel, and T. Schedl. 1995. Control of oogenesis, germline proliferation and sex determination by the C. elegans gene gld-1. Genetics 139:579-606.
13. Francis, R., E. Maine, and T. Schedl. 1995. GLD-1, a cell-type specific tumor suppressor gene in C. elegans. Genetics 139:607-630.
14. Fumagalli, S., N. F. Totty, J. J. Hsuan, and S. A. Courtneidge. 1994. A target for Src in mitosis. Nature 368:867-871.
15. Fusaki, N., A. Iwamatsu, M. Iwahima, and J. Fujisawa. 1997. Interaction between Sam68 and Src family tyrosine kinases, fyn and Ick, in T cell receptor signaling. J. Biol. Chem. 272:6214-6219.
16. Gibson, T. J., J. D. Thompson, and J. Heringa. 1993. The KH domain occurs in a diverse set of RNA-binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid. FEBS Lett. 324: 361-366.
17. Hardy, R. J., C. L. Loushin, V. L. Friedrich, Jr., Q. Chen, T. A. Ebersole, R. A. Lazzarini, and K. Artzt. 1996. Neural cell type-specific expression of QKI proteins is altered in the quaking viable mutant mice. J. Neurosci. 16:7941-7949.
18. Jones, A. R., R. Francis, and T. Schedl. 1996. GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Dev. Biol. 180:165-183.
19. Jones, A. R., and T. Schedl. 1995. Mutations in GLD-1, a female germ cell-specific tumor suppressor gene in C. elegans, affect a conserved domain also found in Sam68. Genes Dev. 9:1491-1504.
20. Lawe, D. C., C. Hahn, and A. J. Wong. 1997. The Nek SH2/SH3 adaptor protein is present in the nucleus with the nuclear protein Sam68. Oncogene 14:223-231.
21. Lock, P., S. Fumagalli, P. Polakis, F. McCormick, and S. A. Courtneidge. 1996. The human p62 cDNA encodes Sam68 and not the ras-GAP-associated p62 protein. Cell 84:23-24.
22. Maa, M.-C., T.-H. Leu, B. J. Trandel, J.-H. Chang, and S. J. Parsons. 1994. A protein that is related to GTPase activating protein-associated p62 complexes with phospholipase Cγ. Mol. Cell. Biol. 14:5466-5473.
23. Mahone, M., E. E. Saffman, and P. F. Lasko. 1995. Localised Bicaudal-C RNA encodes a protein containing a KH domain, the RNA-binding motif for FMR1. EMBO J. 14:2043-2055.
24. McBride, A. E., A. Schlegel, and K. Kirkegaard. 1996. Human protein Sam68 relocalization and interaction with poliovirus RNA polymerase in infected cells. Proc. Natl. Acad. Sci. USA 93:2296-2301.
25. Musco, G., G. Stier, C. Joseph, M. A. Morelli, and A. Pastore. 1996. Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome. Cell 85:237-245.
26. Nussbaum, R. L., and D. H. Ledbetter. 1995. The fragile X syndrome, p. 795-810. In C. R. Scriver, A. Beaudet, W. S. Sly, and D. Valles (ed.), Metabolic basis of inherited disease. McGraw-Hill, New York, N.Y.
27. Pawson, T. 1995. Protein modules and signalling networks. Nature 373:573-580.
28. Pieretti, M., F. Zhang, Y.-H. Fu, S. T. Warren, B. A. Oostra, C. T. Caskey, and D. L. Nelson. 1991. Absence of expression of the FMR-1 gene in fragile X syndrome. Cell 66:817-822.
29. Richard, S., D. Yu, K. J. Blumer, D. Hausladen, M. W. Olszowy, P. A. Connelly, and A. S. Shaw. 1995. Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase Cγ-1. Mol. Cell. Biol. 15:186-197.
30. Richard, S., and H. H. Zingg. 1991. Identification of a retinoic acid response element in the human oxytocin promoter. J. Biol. Chem. 266:21428-21433.
31. Sidman, R. L., M. M. Dickie, and S. H. Appel. 1964. Mutant mice (quaking and jimpy) with deficient myelination in the central nervous system. Science 144:309-311.
32. Siomi, H., M. Choi, M. C. Siomi, R. L. Nussbaum, and G. Dreyfuss. 1994. Essential role for KH domain in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome. Cell 77:33-39.
33. Siomi, H., M. J. Matunis, W. M. Michael, and G. Dreyfuss. 1993. The pre-mRNA binding K protein contains a novel evolutionarily conserved motif. Nucleic Acids Res. 21:1193-1198.
34. Siomi, M. C., Y. Zhang, H. Siomi, and G. Dreyfuss. 1996. Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interaction among them. Mol. Cell. Biol. 16:3825-3832.
35. Taggart, A. K. P., and B. F. Pugh. 1996. Dimerization of TFIID when not bound to DNA. Science 272:1331-1333.
36. Taylor, S. J., M. Anafi, T. Pawson, and D. Shalloway. 1995. Functional interaction between c-src and its mitotic target, Sam68. J. Biol. Chem. 270: 10120-10124.
37. Taylor, S. J., and D. Shalloway. 1994. An RNA-binding protein associated with src through its SH2 and SH3 domains in mitosis. Nature 368:867-871.
38. Toda, T., A. Iida, T. Miwa, Y. Nakamura, and T. Imai. 1994. Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1). Hum. Mol. Genet. 3:465-470.
39. Trub, T., J. D. Frantz, M. Miyazaki, H. Band, and S. E. Shoelson. 1997. The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling. J. Biol. Chem. 272:894-902.
40. Verkerk, A. J. M. H., M. Pieretti, J. S. Sutcliffe, Y.-H. Fu, D. P. Kuhl, A. Pizzuti, O. Reiner, S. Richards, M. F. Victoria, F. Zhang, B. E. Eussen, G. J. B. van Ommen, L. A. J. Blonden, G. J. Riggins, J. L. Chastain, C. B. Kunst, H. Galjaard, C. T. Caskey, D. L. Nelson, B. A. Oostra, and S. T. Warren. 1991. Identification of a gene (FMR1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 65:905-914.
41. Vogel, L. B., and D. J. Fujita. 1995. p70 phosphorylation and binding to p56lck is an early event in interleukin-2 induced onset of cell cycle progression in T-lymphocytes. J. Biol. Chem. 270:2506-2511.
42. Wang, L. L., S, Richard, and A. S. Shaw. 1995. p62 association with RNA is regulated by tyrosine phosphorylation. J. Biol. Chem. 270:2010-2013.
43. Weng, A., S. M. Thomas, R. J. Rickles, J. A. Taylor, A. W. Brauer, C. Seidel-Dugan, W. M. Michael, G. Dreyfuss, and J. S. Brugge. 1994. Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains. Mol. Cell. Biol. 14:4509-4521.
44. Wilson, R., R. Ainscough, K. Anderson, C. Baynes, M. Berks, J. Bonfield, J. Burton, M. Connell, T. Copsey, J. Cooper, et al. 1994. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature 368: 32-38.
45. Wong, G., O. Muller, R. Clark, L. Conroy, M. F. Moran, P. Polakis, and F. McCormick. 1992. Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62. Cell 69:551-558.
46. Zhang, Y., J. P. O'Connor, M. C. Siomi, S. Srinivasan, A. Dutra, R. L. Nussbaum, and G. Dreyfuss. 1995. The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. EMBO J. 14:5358-5366.
47. Zorn, A. M., M. Grow, K. D. Patterson, T. A. Ebersole, Q. Chen, K. Artzt, and P. A. Krieg. 1997. Remarkable sequence conservation of transcripts encoding amphibian and mammalian homologues of quaking, a KH domain RNA-binding protein. Gene 188:199-206.