The yeast poly(A)-binding protein Pab1p stimulates in vitro poly(A)-dependent and cap-dependent translation by distinct mechanisms

EMBO Journal

Volumn 18, Issue 11, 1999, Pages 3153-3163

  Otero, Lucy J ^a   Ashe, Mark P ^a   Sachs, Alan B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Poly(A); RNA binding protein; Translation; Translation initiation factors; Yeast

Indexed keywords

BINDING PROTEIN; INITIATION FACTOR 4E; POLYADENYLATED RNA; POLYADENYLIC ACID;

ARTICLE; BIOCHEMISTRY; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RNA CAPPING; SACCHAROMYCES CEREVISIAE; TRANSACTIVATION; TRANSLATION INITIATION; YEAST;

ALLELES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CONSERVED SEQUENCE; EUKARYOTIC INITIATION FACTOR-4G; HUMANS; MODELS, GENETIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE INITIATION FACTORS; POLY A; POLY(A)-BINDING PROTEINS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; RNA CAPS; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; TRANS-ACTIVATION (GENETICS);

SACCHAROMYCES CEREVISIAE;

EID: 0033153302     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.11.3153     Document Type: Article

References (29)

1. Adam, S.A., Nakagawa, T., Swanson, M.S., Woodruff, T.K. and Dreyfuss, G.(1986) mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence. Mol. Cell. Biol., 6, 2932-2943.
2. Anderson, J., Paddy, M. and Swanson, M. (1993) PUB1 is a major nuclear and cytoplasmic polyadenylated RNA-binding protein in Saccharomyces cerevisiae. Mol. Cell. Biol., 13, 102-112.
3. Barettino, D., Feigenbutz, M., Valcarcel, R. and Stunnenberg, H.G. (1993) Improved method for PCR-mediated site-directed mutagenesis. Nucleic Acids Res., 22, 541-542.
4. Boeke, J.D., Trueheart, J., Natsoulis, G. and Fink, G. (1987) 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. In Abelson, J. and Simon, M.I. (eds), Methods in Enzymology. Academic Press, San Diego, CA, Vol. 154, pp. 164-175.
5. Deardorff, J.A. and Sachs, A.B. (1997) Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast poly(A)-binding protein. J. Mol. Biol., 269, 67-81.
6. Gallie, D.R. (1991) The cap and the poly(A) tail function synergistically to regulate mRNA translational efficiency. Genes Dev., 5, 2108-2116.
7. Gingras, A.-C., Raught, B. and Sonenberg, N. (1999) eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu. Rev. Biochem., in press.
8. Goyer, C., Altmann, M., Lee, H.S., Blanc, A., Deshmukh, M., Woolford, J.L., Trachsel, H. and Sonenberg, N. (1993) TIF4631 and TIF4632: two genes encoding the high-molecular weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif sequence and carry out an essential function. Mol. Cell. Biol., 13, 4860-4874.
9. Iizuka, N., Najita, L., Franzusoff, A. and Sarnow, P. (1994) Cap-dependent and cap-independent translation by internal initiation of mRNAs in cell extracts prepared from Saccharomyces cerevisiae. Mol. Cell. Biol., 14, 7322-7330.
10. Imataka, H., Gradi, A. and Sonenberg, N. (1998) A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation. EMBO J., 17, 7480-7489.
11. Jackson, M. and Wickens, M. (1997) Translational controls impinging on the 5′-untranslated region and initiation factor proteins. Curr. Opin. Genet. Dev., 7, 233-241.
12. Jacobson, A. (1996) Poly(A) metabolism and translation: the closed-loop model. In Hershey, J.W.B., Mathews, M.B. and Sonenberg, N. (eds), Translational Control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, Vol. 30, pp. 451-480.
13. Jacobson, A. and Favreau, M. (1983) Possible involvement of poly(A) in protein synthesis. Nucleic Acids Res., 11, 6353-6368.
14. Keller, W. and Minvielle-Sebastia, L. (1997) A comparison of mammalian and yeast pre-mRNA 3′-end processing. Curr. Opin. Cell Biol., 9, 329-336.
15. Kenan, D.J., Query, C.C. and Keene, J.D. (1991) RNA recognition: towards identifying determinants of specificity. Trends Biochem. Sci., 16, 214-220.
16. Kessler, S.H. and Sachs, A.B. (1998) RNA recognition motif 2 of yeast Pablp is required for its functional interaction with eukaryotic translation initiation factor 4G. Mol. Cell. Biol., 18, 51-57.
17. Merrick, W.C. and Hershey, J.W.B. (1996) The pathway and mechanism of eukaryotic protein synthesis. In Hershey, J.W.B., Mathews, M.B. and Sonenberg, N. (eds), Translational Control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, Vol. 30, pp. 31-69.
18. Munroe, D. and Jacobson, A. (1990) mRNA poly(A) tail, a 3′ enhancer of translation initiation. Mol. Cell. Biol., 10, 3441-3455.
19. Nagai, K., Oubridge, C., Jessen, T.H., Li, J. and Evans, P.R. (1990) Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A. Nature, 348, 515-520.
20. Piron, M., Vende, P., Cohen, J. and Poncet, D. (1998) Rotavirus RNA-binding protein NSP3 interacts with eIF4G1 and evicts poly(A)-binding protein from eIF4F. EMBO J., 17, 5811-5821.
21. Sachs, A.B. and Davis, R.W. (1989) The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. Cell, 58, 857-867.
22. Sachs, A.B. and Davis, R.W. (1990) Translation initiation and ribosomal biogenesis: involvement of a putative rRNA helicase and RPL46. Science, 247, 1077-1079.
23. Sachs, A.B., Bond, M.W. and Kornberg, R.D. (1986) A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: domain structure and expression. Cell, 45, 827-835.
24. Sachs, A.B., Davis, R.W. and Kornberg, R.D. (1987) A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability. Mol. Cell. Biol., 7, 3268-3276.
25. Sachs, A.B., Sarnow, P. and Hentze, M.W. (1997) Starting at the beginning, middle and end: translation initiation in eucaryotes. Cell, 89, 831-838.
26. Tarun, S. and Sachs, A.B. (1995) A common function for mRNA 5′ and 3′ ends in translation initiation in yeast. Genes Dev., 9. 2997-3007.
27. Tarun, S.Z. and Sachs, A.B. (1996) Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G. EMBO J., 15, 7168-7177.
28. Tarun, S.Z., Wells, S.E., Deardorff, J.A. and Sachs, A.B. (1997) Translation initiation factor eIF-4G mediates in vitro poly(A) tail-dependent translation. Proc. Natl Acad. Sci. USA, 94, 9046-9051.
29. Wells, S.E., Hillner, P., Vale, R. and Sachs, A.B. (1998) Circularization of mRNA by eucaryotic translation initiation factors. Mol. Cell, 2, 135-140.