Neurotrophin-induced transport of a β-actin mRNP complex increases β-actin levels and stimulates growth cone motility

Neuron

Volumn 31, Issue 2, 2001, Pages 261-275

  Zhang, H L ^a   Eom, T ^a   Oleynikov, Y ^b   Shenoy, S M ^b   Liebelt, D A ^a,b   Dictenberg, J B ^a,b   Singer, R H ^b   Bassell, G J ^a  

^a New York State Office of Mental Retardation and Developmental Disabilities   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BETA ACTIN; BINDING PROTEIN; MESSENGER RNA; NEUROTROPHIN; NEUROTROPHIN 3; UNCLASSIFIED DRUG; ZIPCODE BINDING PROTEIN 1;

3' UNTRANSLATED REGION; ANALYTIC METHOD; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; GENE LOCATION; GENE SEQUENCE; GENETIC TRANSFECTION; GROWTH CONE; IMAGING; NERVE CELL; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT;

EID: 0035797518     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(01)00357-9     Document Type: Article

References (55)

1. Transport and localization of exogenous myelin basic protein mRNA microinjected into oligodendrocytes
2. Transport and localization elements in MBP mRNA
3. Neuronal RNA localization and the cytoskeleton
4. Association of poly(A) mRNA with microtubules in cultured neurons
5. Sorting of β-actin mRNA and protein to neurites and growth cones in culture
6. cis-Acting signals and trans-acting proteins are involved in tau mRNA targeting into neurites of differentiating neuronal cells
7. Localization of ASH1 RNA particles in living yeast
8. Identification of a cis-acting dendritic targeting element in MAP2 mRNAs
9. A function for kinesin I in the posterior transport of oskar mRNA
10. Translocation of MBP mRNA in oligodendrocytes requires microtubules and kinesin
11. Molecular characterization of the dendritic growth cone
12. A highly conserved RNA binding protein for cytoplasmic mRNA localization in vertebrates
13. Vg1 RNA binding protein mediates the association of Vg1 RNA with microtubules in Xenopus oocytes
14. Localized sources of neurotrophins initiate axon collateral sprouting
15. Intracellular localization of tropomyosin mRNA and protein is associated with development of neuronal polarity
16. RNA binding protein conserved in both microtubule and microfilament based RNA localization
17. Kinesin and dynein superfamily proteins and the mechanism of organelle transport
18. hnRNPA2 selectively binds the cytoplasmic transport sequence of MBP mRNA
19. Improved lipid mediated gene transfer into primary cultures of hippocampal neurons
20. Molecular insights into mRNA transport and local translation in the mammalian nervous system
21. The mammalian Staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: Implications for its involvement in mRNA transport
22. Sequences responsible for intracellular localization of β-actin messenger RNA also affect cell phenotype
23. Beta-actin messenger RNA localization and protein sythesis augment cell motility
24. Development of subcellular mRNA compartmentation in hippocampal neurons in culture
25. Neurotrophin-3 signals redistribute RNA in neurons
26. Translocation of RNA granules in living neurons
27. Microtubule dependent recruitment of Staufen-GFP into large RNA containing granules and dendritic transport in living hippocampal neurons
28. The cis-acting RNA trafficking signal from myelin basic protein mRNA and its cognate trans-acting ligand hnRNP A2 enhance cap-dependent translation
29. A rho-dependent signaling pathway operating through myosin localizes β-actin mRNA in fibroblasts
30. Subcellular localization of tau mRNA in differentiating neuronal cell culture: Implications for neuronal polarity
31. Microtubules are involved in the localization of tau mRNA in primary neuronal cultures
32. Exogenous tau mRNA is localized in oocytes: Possible evidence for evolutionary conservation of localization mechanisms
33. Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA
34. The 3′UTR of CaMKIIα mRNA is a cis-acting signal for the localization and translation of mRNA in dendrites
35. Two cis-acting elements in the 3′UTR of CaMKIIα regulate its dendritic targeting
36. Mutational analysis of a heterogeneous nuclear ribonucleoprotein A2 response element for RNA trafficking
37. Actin dynamics in growth cones
38. Regulating actin dynamics in neuronal growth cones
39. Neurotrophins as in vitro guidance molecules for embryonic sensory neurons
40. Two trans-acting rat-brain proteins, MARTA1 and MARTA2, interact specifically with the dendritic targeting elment in MAP2 mRNAs
41. CaMKIIα 3′UTR directed mRNA translocation in living neurons: Visualization by GFP linkage
42. Characterization of a β-Actin mRNA zipcode-binding protein
43. The molecular motor dynein is involved in targeting Swallow and bicoid RNA to the anterior pole of Drosophila oocytes
44. Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation
45. The physiological significance of β-actin mRNA localization in determining cell polarity and directional motility
46. Indirect association of ezrin with F-actin: Isoform specificity and calcium sensitivity
47. Protein synthesis at synaptic sites on dendrites
48. Requirement of microfilaments in sorting of actin mRNAs
49. Translational machinery in dendrites of hippocampal neurons in culture
50. RNA, whither goest thou
51. Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles
52. A two-step model for the localization of maternal mRNA in Xenopus oocytes: Involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA
53. Neurotrophin regulation of beta-actin mRNA and protein localization within growth cones
54. A novel cytoplasmic protein with RNA binding motifs is an autoantigen in human hepatocellular carcinoma
55. Vg1 RBP distribution and evolutionarily conserved expression at multiple stages during development