메뉴 건너뛰기




Volumn 10, Issue 7, 1996, Pages 826-835

Tissue-specific inactivation of p53 tumor suppression in the mouse

Author keywords

apoptosis; cancer; cell specificity; p53; transgenic mice

Indexed keywords

PROTEIN P53;

EID: 0029916320     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.7.826     Document Type: Article
Times cited : (71)

References (44)
  • 1
    • 0026039802 scopus 로고
    • Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens
    • Chen, J. and T. Van Dyke. 1991. Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens. Mol Cell Biol. 11: 5968-5976.
    • (1991) Mol Cell Biol. , vol.11 , pp. 5968-5976
    • Chen, J.1    Van Dyke, T.2
  • 2
    • 0026578113 scopus 로고
    • T Antigen mutant activities in transgenic mice: Roles of p53 and pRB-binding in tumorigenesis of the choroid plexus
    • Chen, J., G. Tobin, J.M. Pipas, and T.A. Van Dyke. 1992. T Antigen mutant activities in transgenic mice: Roles of p53 and pRB-binding in tumorigenesis of the choroid plexus. Oncogene 7: 1167-1175.
    • (1992) Oncogene , vol.7 , pp. 1167-1175
    • Chen, J.1    Tobin, G.2    Pipas, J.M.3    Van Dyke, T.A.4
  • 4
    • 0019474723 scopus 로고
    • A monoclonal antibody that recognizes B cells and B cell precursors in mice
    • Coffmann, R.L. and I.L. Weissman. 1981. A monoclonal antibody that recognizes B cells and B cell precursors in mice. J. Exp. Med. 153: 269-279.
    • (1981) J. Exp. Med. , vol.153 , pp. 269-279
    • Coffmann, R.L.1    Weissman, I.L.2
  • 5
    • 0025800127 scopus 로고
    • Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region
    • Costa, R.H. and D.R. Grayson. 1991. Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region. Nucleic Acids Res. 19: 4139-4145.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 4139-4145
    • Costa, R.H.1    Grayson, D.R.2
  • 6
    • 0009802608 scopus 로고
    • A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes
    • Costa, R.H., D.R. Grayson, K.G. Xanthopoulos, and J.E. Darnell. 1988. A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes. Proc. Natl. Acad. Sci. 85: 3840-3844.
    • (1988) Proc. Natl. Acad. Sci. , vol.85 , pp. 3840-3844
    • Costa, R.H.1    Grayson, D.R.2    Xanthopoulos, K.G.3    Darnell, J.E.4
  • 9
    • 0028294898 scopus 로고
    • Down-regulation of wild-type p53 activity interfers with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal
    • Gottlieb, E., R. Haffner, T. von Ruden, E. Wagner, and M. Oren. 1994. Down-regulation of wild-type p53 activity interfers with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. EMBO J. 13: 1368-1374.
    • (1994) EMBO J. , vol.13 , pp. 1368-1374
    • Gottlieb, E.1    Haffner, R.2    Von Ruden, T.3    Wagner, E.4    Oren, M.5
  • 10
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt, M.S., W.P. Bennett, M Hollstein, and C.C. Harris. 1994. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res. 54: 4855-4878.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 11
    • 0028899283 scopus 로고
    • Biochemical properties and biological effects of p53
    • Haffner, R. and M. Oren. 1995. Biochemical properties and biological effects of p53. Curr. Opin. Genet. Dev. 5(1): 84-94.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , Issue.1 , pp. 84-94
    • Haffner, R.1    Oren, M.2
  • 12
    • 0019401161 scopus 로고
    • Monoclonal antibodies specific for simian virus 40 tumor antigens
    • Harlow, E., L.V. Crawford, D.C. Pim, and N.M. Williamson. 1981. Monoclonal antibodies specific for simian virus 40 tumor antigens. J. Virol. 39: 861-869.
    • (1981) J. Virol. , vol.39 , pp. 861-869
    • Harlow, E.1    Crawford, L.V.2    Pim, D.C.3    Williamson, N.M.4
  • 14
    • 0028842340 scopus 로고
    • A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice
    • Harvey, M., H. Vogel, D. Morris, A. Bradley, A. Bernstein, and L.A. Donehower. 1995. A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice. Nature Genet. 9: 305-311.
    • (1995) Nature Genet. , vol.9 , pp. 305-311
    • Harvey, M.1    Vogel, H.2    Morris, D.3    Bradley, A.4    Bernstein, A.5    Donehower, L.A.6
  • 15
    • 0028066774 scopus 로고
    • Tumor suppressor genes
    • Hinds, P.W. and R.A. Weinberg. 1994. Tumor suppressor genes. Curr. Biol. 4: 135-141.
    • (1994) Curr. Biol. , vol.4 , pp. 135-141
    • Hinds, P.W.1    Weinberg, R.A.2
  • 17
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • Howes, K.A., N. Ransom, D.S. Papermaster, J.G.H. Lasudry, D.M. Albert, and J.J. Windle. 1994. Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes & Dev. 8: 1300-1310.
    • (1994) Genes & Dev. , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, N.2    Papermaster, D.S.3    Lasudry, J.G.H.4    Albert, D.M.5    Windle, J.J.6
  • 19
    • 0028927179 scopus 로고
    • P53, cell cycle control and apoptosis: Implications for cancer
    • Kastan, M.B., C.E. Canman, and C.J. Leonard. 1995. P53, cell cycle control and apoptosis: Implications for cancer. Cancer Metastasis Rev. 14: 3-15.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 3-15
    • Kastan, M.B.1    Canman, C.E.2    Leonard, C.J.3
  • 20
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane, D.P. 1992. p53, guardian of the genome. Nature 358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 21
    • 0027326586 scopus 로고
    • The tumor suppressor genes
    • Levine A.J. 1993. The tumor suppressor genes. Annu. Rev. Biochem. 62: 623-651.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 623-651
    • Levine, A.J.1
  • 22
    • 0025876591 scopus 로고
    • The p53 tumour suppressor gene
    • Levine, A.J., J. Momand, and C.A. Finlay. 1991. The p53 tumour suppressor gene. Nature 351: 453-456.
    • (1991) Nature , vol.351 , pp. 453-456
    • Levine, A.J.1    Momand, J.2    Finlay, C.A.3
  • 23
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S.W., E.M. Schmitt, S.W. Smith, B.A. Osborne, and T. Jacks. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 24
    • 0026060757 scopus 로고
    • The tumour suppressor p53: Analysis of wild type and mutant p53 complexes
    • Milner, J., E.A. Medcalf, and A.C. Cook. 1991. The tumour suppressor p53: Analysis of wild type and mutant p53 complexes. Mol. Cell. Biol. 11: 12-19.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 12-19
    • Milner, J.1    Medcalf, E.A.2    Cook, A.C.3
  • 25
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S., B. Williams, T. Jacks, and R. DePinho. 1994. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371: 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.1    Williams, B.2    Jacks, T.3    DePinho, R.4
  • 26
    • 0028334011 scopus 로고
    • Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
    • Pan, H and A E. Griep. 1994 Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development. Genes & Dev. 8: 1285-1299.
    • (1994) Genes & Dev. , vol.8 , pp. 1285-1299
    • Pan, H.1    Griep, A.E.2
  • 27
    • 0029093605 scopus 로고
    • Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
    • _. 1995. Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes & Dev. 9: 2157-2169.
    • (1995) Genes & Dev. , vol.9 , pp. 2157-2169
  • 28
    • 0028172574 scopus 로고
    • p53 and Rb: Their cellular roles
    • Picksley, S.M. and D.P. Lane. 1994. p53 and Rb: Their cellular roles. Curr. Opin. Cell Biol. 6(6): 853-858.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , Issue.6 , pp. 853-858
    • Picksley, S.M.1    Lane, D.P.2
  • 29
    • 0020625930 scopus 로고
    • Mutational analysis of simian virus 40 T antigen: Isolation and characterization of mutants with deletions in the T-antigen gene
    • Pipas, J.M., K.W. Peden, and D. Nathans. 1983. Mutational analysis of simian virus 40 T antigen: Isolation and characterization of mutants with deletions in the T-antigen gene Mol Cell. Biol. 3: 203-213.
    • (1983) Mol Cell. Biol. , vol.3 , pp. 203-213
    • Pipas, J.M.1    Peden, K.W.2    Nathans, D.3
  • 30
    • 0028226679 scopus 로고
    • Induction versus progression of brain tumor development. Differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen
    • Saenz-Robles, M T., H. Symonds, J. Chen, and T. Van Dyke. 1994. Induction versus progression of brain tumor development. Differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen. Mol. Cell. Biol. 14(41): 2686-2698.
    • (1994) Mol. Cell. Biol. , vol.14 , Issue.41 , pp. 2686-2698
    • Saenz-Robles, M.T.1    Symonds, H.2    Chen, J.3    Van Dyke, T.4
  • 31
    • 0026446686 scopus 로고
    • Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding
    • Shaulian, E., A. Zauberman, D. Ginsberg, and M. Oren. 1992. Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding. Mol. Cell. Biol. 12: 5581-5592.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5581-5592
    • Shaulian, E.1    Zauberman, A.2    Ginsberg, D.3    Oren, M.4
  • 32
    • 0028930859 scopus 로고
    • Transcriptional repression by the C-terminal domain of p53
    • Shaulian, E., I. Haviv, Y. Shaul, and M. Oren. 1995. Transcriptional repression by the C-terminal domain of p53. Oncogene 10(4): 671-680.
    • (1995) Oncogene , vol.10 , Issue.4 , pp. 671-680
    • Shaulian, E.1    Haviv, I.2    Shaul, Y.3    Oren, M.4
  • 33
    • 0026560995 scopus 로고
    • Formation of stable p53 homotetramers and multiples of tetramers
    • Stenger, J.E., G.A. Mayr, K. Mann, and P. Tegtmeyer. 1992. Formation of stable p53 homotetramers and multiples of tetramers. Mol. Carcinog. 5: 102-106.
    • (1992) Mol. Carcinog. , vol.5 , pp. 102-106
    • Stenger, J.E.1    Mayr, G.A.2    Mann, K.3    Tegtmeyer, P.4
  • 34
    • 0026637484 scopus 로고
    • A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization
    • Sturzbecher, H.W., R. Brain, C. Addison, K. Rudge, M. Remm, M. Gnmaldi, E. Keenan, and J.R. Jenkins. 1992. A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization. Oncogene 7(8): 1513-1523.
    • (1992) Oncogene , vol.7 , Issue.8 , pp. 1513-1523
    • Sturzbecher, H.W.1    Brain, R.2    Addison, C.3    Rudge, K.4    Remm, M.5    Gnmaldi, M.6    Keenan, E.7    Jenkins, J.R.8
  • 35
    • 0027269675 scopus 로고
    • Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant
    • Symonds, H.S., S.A. McCarthy, J. Chen, J.M. Pipas, and T. Van Dyke. 1993. Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant. Mol Cell. Biol. 13: 3255-3265.
    • (1993) Mol Cell. Biol. , vol.13 , pp. 3255-3265
    • Symonds, H.S.1    McCarthy, S.A.2    Chen, J.3    Pipas, J.M.4    Van Dyke, T.5
  • 38
    • 0026535237 scopus 로고
    • p53: A transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer
    • Unger, T., M.M. Nau, S. Segal, and J.D. Minna. 1992. p53: A transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer. EMBO J. 11: 1383-1390.
    • (1992) EMBO J. , vol.11 , pp. 1383-1390
    • Unger, T.1    Nau, M.M.2    Segal, S.3    Minna, J.D.4
  • 39
    • 0027182946 scopus 로고
    • Functional domains of wild-type and mutant proteins involved in transcriptonal regulation, transdominant inhibition, and transformation suppression
    • Unger, T., J.A. Mietz, M. Scheffner, C.L. Yee, and P.M. Howley. 1993. Functional domains of wild-type and mutant proteins involved in transcriptonal regulation, transdominant inhibition, and transformation suppression. Mol Cell Biol. 13: 5186-5194.
    • (1993) Mol Cell Biol. , vol.13 , pp. 5186-5194
    • Unger, T.1    Mietz, J.A.2    Scheffner, M.3    Yee, C.L.4    Howley, P.M.5
  • 40
    • 0022033631 scopus 로고
    • Precise epitope mapping of the murine transformation-associated protein, p53
    • Wade Evans, A. and J.R Jenkins. 1985. Precise epitope mapping of the murine transformation-associated protein, p53. EMBO J. 4: 699-706.
    • (1985) EMBO J. , vol.4 , pp. 699-706
    • Wade Evans, A.1    Jenkins, J.R.2
  • 42
    • 0030067581 scopus 로고    scopus 로고
    • Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21, halts hepatocyte cell cycle progression, postnatal liver development, and regeneration
    • Wu, H., M. Wade, L. Krall, J. Grisham, Y. Xiong, and T. Van Dyke. 1996. Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21, halts hepatocyte cell cycle progression, postnatal liver development, and regeneration. Genes &. Dev. 10: 245-260.
    • (1996) Genes &. Dev. , vol.10 , pp. 245-260
    • Wu, H.1    Wade, M.2    Krall, L.3    Grisham, J.4    Xiong, Y.5    Van Dyke, T.6
  • 43
    • 0025008962 scopus 로고
    • Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice
    • Yan, C., R.H. Costa, J.E. Darnell, J.D. Chen, and T.A. Van Dyke. 1990. Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice. EMBO J. 9: 869-878.
    • (1990) EMBO J. , vol.9 , pp. 869-878
    • Yan, C.1    Costa, R.H.2    Darnell, J.E.3    Chen, J.D.4    Van Dyke, T.A.5
  • 44
    • 0027234492 scopus 로고
    • A comparison of the biological activities of wild-type and mutant p53
    • Zambetti, G. and A. Levine. 1993. A comparison of the biological activities of wild-type and mutant p53. FASEB J. 7: 855-865.
    • (1993) FASEB J. , vol.7 , pp. 855-865
    • Zambetti, G.1    Levine, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.