A bipartite yeast SSRP1 analog comprised of Pob3 and Nhp6 proteins modulates transcription

Molecular and Cellular Biology

Volumn 21, Issue 10, 2001, Pages 3491-3502

  Brewster, N K ^a   Johnston, G C ^a   Singer, R A ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AZAURACIL; HIGH MOBILITY GROUP PROTEIN; HYBRID PROTEIN; NUCLEAR PROTEIN; PROTEIN;

ARTICLE; IMMUNOPRECIPITATION; NONHUMAN; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

CARRIER PROTEINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HIGH MOBILITY GROUP PROTEINS; NUCLEAR PROTEINS; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE; VERTEBRATA;

EID: 0035027953     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.10.3491-3502.2001     Document Type: Article

References (62)

1. Molecular analysis of SNF2 and SNF5, genes required for expression of glucose-repressible genes in Saccharomyces cerevisiae
2. Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding
3. Continuous and widespread roles for the Swi-Snf complex in transcription
4. Evidence that Spt6p controls chromatin structure by a direct interaction with histones
5. Characterization of the CP complex, an abundant dimer of Cdc68 and Pob3 proteins that regulates yeast transcriptional activation and chromatin repression
6. TFG3/TAF30/ANC1, a component of the yeast SWI/SNF complex that is similar to the leukemogenic proteins ENL and AF-9
7. Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF
8. The H3/H4 tetramer blocks transcript elongation by RNA polymerase II in vitro
9. Multifunctional yeast high-copy-number shuttle vectors
10. NHP6A and NHP6B, which encode HMG1-like proteins, are candidates for downstream components of the yeast SLT2 mitogen-activated protein kinase pathway
11. 'Marker swap' plasmids: Convenient tools for budding yeast molecular genetics
12. The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae
13. The yeast protein complex containing Cdc68 and Pob3 mediates core-promoter repression through the Cdc68 N-terminal domain
14. Mutation and modeling analysis of the Saccharomyces cerevisiae Swi6 ankyrin repeats
15. 6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae
16. Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: Characterization of an Ada complex and the SAGA (Spt/Ada) complex
17. IIs are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation
18. Chromatin remodelling at the PHO8 promoter requires SWI-SNF and SAGA at a step subsequent to activator binding
19. Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae
20. TFIIF-TAF-RNA polymerase II connection
21. Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure
22. II30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex
23. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity
24. Duplicated NHP6 genes of Saccharomyces cerevisiae encode proteins homologous to bovine high mobility group protein 1
25. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations
26. Positive DNA supercoiling generates a chromatin conformation characteristic of highly active genes
27. Requirement of RSF and FACT for transcription of chromatin templates in vitro
28. Characterization of a high mobility group 1/2 homolog in yeast
29. Differential effects of Cdc68 on cell cycle-regulated promoters in Saccharomyces cerevisiae
30. Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promoter function in Saccharomyces cerevisiae
31. Purification, gene cloning, and gene disruption of the transcription factor SII in Saccharomyces cerevisiae
32. A DNA unwinding factor involved in DNA replication in cell-free extracts of Xenopus eggs
33. FACT, a factor that facilitates transcript elongation through nucleosomes
34. The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins
35. DNA looping by Saccharomyces cerevisiae high mobility group proteins NHP6A/B
36. Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro
37. Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement
38. Role for ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression
39. Mutations that suppress the deletion of an upstream activating sequence in yeast: Involvement of a protein kinase and histone H3 in repressing transcription in vivo
40. DNA-binding properties of the yeast SWI/SNF complex
41. Mutations in both the structured domain and N-terminus of histone H2B bypass the requirement for Swi-Snf in yeast
42. Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes
43. CDC68, a yeast gene that affects regulation of cell proliferation and transcription, encodes a protein with a highly acidic carboxyl terminus
44. Tra1p is a component of the yeast Ada-Spt transcriptional regulatory complexes
45. POB3 is required for both transcription and replication in the yeast Saccharomyces cerevisiae
46. The MSN1 and NHP6A genes suppress SW16 defects in Saccharomyces cerevisiae
47. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
48. The nucleosome remodeling complex, Snf/Swi, is required for the maintenance of transcription in vivo and is partially redundant with the histone acetyltransferase, Gcn5
49. SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat
50. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
51. FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH
52. Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes
53. Analysis of SPT genes: A genetic approach toward analysis of TFIID, histones, and other transcription factors of yeast
54. Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection
55. The Saccharomyces cerevisiae DNA polymerase α catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein
56. Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase α
57. Alteration of nucleosome structure as a mechanism of transcriptional regulation
58. The Saccharomyces cerevisiae Cdc68 transcription activator is antagonized by San1, a protein implicated in transcriptional silencing
59. Sug1 modulates yeast transcription activation by Cdc68
60. NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
61. Determinants of DNA binding and bending by the Saccharomyces cerevisiae high mobility group protein NHP6A that are important for its biological activities
62. Architectural transcription factors and the SAGA complex function in parallel pathways to activate transcription