Functional diversity of protein C-termini: More than zipcoding?

Trends in Cell Biology

Volumn 12, Issue 3, 2002, Pages 146-150

  Chung, Jean Ju ^a   Shikano, Sojin ^a   Hanyu, Yoshiro ^b   Li, Min ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYL GROUP; EPITOPE; LIPID; PROTEIN;

AMINO ACID SEQUENCE; CARBOXY TERMINAL SEQUENCE; CELL ACTIVITY; CELL ANCHORAGE; CELL FUNCTION; CELL SPECIFICITY; COMPLEX FORMATION; CYTOLOGY; MACROMOLECULE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NERVE CELL; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROKARYOTE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN TARGETING; PROTEOMICS; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; TERMINAL SEQUENCE;

AMINO ACID MOTIFS; ANIMALS; HUMANS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; PROTEINS;

MAMMALIA; PROKARYOTA;

EID: 0036498862     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0962-8924(01)02241-3     Document Type: Review

References (55)

1. The N-end rule: Functions, mysteries, uses
2. Prediction of N-terminal protein sorting signals
3. Structure of the C-terminal end of the nascent peptide influences translation termination
4. Applications of display technology in protein analysis
5. PDZ domains and the organization of supramolecular complexes
6. PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences
7. Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
8. TRP trapped in fly signaling web
9. Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity
10. PDZ domains: More than just a glue
11. TAZ: A novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
12. Substrate recognition through a PDZ domain in tail-specific protease
13. The PDZ domain of the spoivb serine peptidase facilitates multiple functions
14. Sequence determinants of C-terminal substrate recognition by the Tsp protease
15. Tsp: A tail-specific protease that selectively degrades proteins with nonpolar C termini
16. SMART: A web-based tool for the study of genetically mobile domains
17. Tetratrico peptide repeat interactions: To TPR or not to TPR?
18. Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: Evidence that PTS1 protein import is mediated by a cycling receptor
19. ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway
20. Solution structure of a Nedd4 WW domain-ENaC peptide complex
21. A novel ligand-binding site in the zeta-form 14-3-3 protein recognizing the platelet glycoprotein Ibα and distinct from the c-Raf-binding site
22. Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide
23. Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex
24. Protein lipidation in cell signaling
25. Acylation of Escherichia coli hemolysin: A unique protein lipidation mechanism underlying toxin function
26. Protein prenylation: Molecular mechanisms and functional consequences
27. Binding of the delta subunit to rod phosphodiesterase catalytic subunits requires methylated, prenylated C-termini of the catalytic subunits
28. Regulation of specific DNA binding by p53: Evidence for a role for O-glycosylation and charged residues at the carboxy-terminus
29. Regulation of the specific DNA binding function of p53
30. Regulation of Mdm2-directed degradation by the C terminus of p53
31. Protein interactions at the carboxyl terminus of p53 result in the induction of its in vitro transactivation potential
32. p300/CBP/p53 interaction and regulation of the p53 response
33. A TPR motif cofactor contributes to p300 activity in the p53 response
34. Carboxy-terminal determinants of intracellular protein degradation
35. Degradation of carboxy-terminal-tagged cytoplasmic proteins by the Escherichia coli protease HflB (FtsH)
36. PDZ-like domains mediate binding specificity in the Clp/Hsp100 family of chaperones and protease regulatory subunits
37. Stability of the Escherichia coli division inhibitor protein MinC requires determinants in the carboxy-terminal region of the protein
38. Functional dissection of a cell-division inhibitor, SulA, of Escherichia coli and its negative regulation by Lon
39. Assembly, intracellular targeting and cell surface expression of the human N-methyl-D-aspartate receptor subunits NR1a and NR2A in transfected cells
40. An additional serine residue at the C terminus of rhodanese destabilizes the enzyme
41. Regulation of ubiquitination and degradation of p53 in unstressed cells through C-terminal phosphorylation
42. Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking
43. Regulation of neuronal function by protein trafficking: A role for the endosomal pathway
44. Tight junction, a platform for trafficking and signaling protein complexes
45. G protein-coupled receptor (GPCR) trafficking in the central nervous system: Relevance for drugs of abuse
46. Signal-dependent membrane protein trafficking in the endocytic pathway
47. Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus
48. Different fate of a single reporter protein containing KDEL or KKXX targeting signals stably expressed in mammalian cells
49. A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels
50. A di-acidic signal required for selective export from the endoplasmic reticulum
51. Efficient export of the vesicular stomatitis virus G protein from the endoplasmic reticulum requires a signal in the cytoplasmic tail that includes both tyrosine-based and di-acidic motifs
52. Role of ER export signals in controlling surface potassium channel numbers
53. Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein
54. Peroxisome biogenesis and peroxisome biogenesis disorders
55. A proposed model for the PEX5-peroxisomal targeting signal-1 recognition complex