-
1
-
-
15144355572
-
6-OHDA neurotoxicity is prevented by selegiline and its metabolites
-
Ahola T, Haapalinna A, Heinonen E, Suhonen J and Hervonen A (1993) 6-OHDA neurotoxicity is prevented by selegiline and its metabolites. Soc Neurosci Abstr 20:674.2.
-
(1993)
Soc Neurosci Abstr
, vol.20
, pp. 6742
-
-
Ahola, T.1
Haapalinna, A.2
Heinonen, E.3
Suhonen, J.4
Hervonen, A.5
-
2
-
-
0029658081
-
Absorption and presystemic metabolism of selegiline hydrochloride at different regions in the gastrointestinal tract in healthy males
-
Barrett JS, Szego P, Rohatagi S, Morales RJ, DeWitt KE, Rajewski G and Ireland J (1996) Absorption and presystemic metabolism of selegiline hydrochloride at different regions in the gastrointestinal tract in healthy males. Pharm Res 13:1535-1540.
-
(1996)
Pharm Res
, vol.13
, pp. 1535-1540
-
-
Barrett, J.S.1
Szego, P.2
Rohatagi, S.3
Morales, R.J.4
DeWitt, K.E.5
Rajewski, G.6
Ireland, J.7
-
3
-
-
0003079139
-
Lactic dehydrogenase
-
Bergmeyer H-U, ed Academic Press, New York
-
Bergmeyer H-U, Bernt E and Hess B (1963) Lactic dehydrogenase, in Methods of Enzymatic Analysis (Bergmeyer H-U, ed) pp 736-741, Academic Press, New York.
-
(1963)
Methods of Enzymatic Analysis
, pp. 736-741
-
-
Bergmeyer, H.-U.1
Bernt, E.2
Hess, B.3
-
4
-
-
0030057990
-
Age-dependent sensitivity of cultured peripheral sympathetic neurons to 1-methyl-4-phenylpyridinium: Role of glutathione
-
Bhave SV, Johannessen JN, Lash LH, Wakade TD and Wakade AR (1996) Age-dependent sensitivity of cultured peripheral sympathetic neurons to 1-methyl-4-phenylpyridinium: role of glutathione. J Neurochem 67:557-565.
-
(1996)
J Neurochem
, vol.67
, pp. 557-565
-
-
Bhave, S.V.1
Johannessen, J.N.2
Lash, L.H.3
Wakade, T.D.4
Wakade, A.R.5
-
5
-
-
0025583426
-
Kinetic evaluation of MAO-B-activity following oral administration of selegiline and desmethyl-selegiline in rat
-
Borbe HO, Niebch G and Nickel B (1990) Kinetic evaluation of MAO-B-activity following oral administration of selegiline and desmethyl-selegiline in rat. J Neural Transm 32(Suppl.):131-137.
-
(1990)
J Neural Transm
, vol.32
, Issue.SUPPL.
, pp. 131-137
-
-
Borbe, H.O.1
Niebch, G.2
Nickel, B.3
-
6
-
-
0026745490
-
Effect of ethylcholine mustard aziridinium (AF64A) and of the monoamine oxidase-B-inhibitor L-deprenyl on the morphology of the rat hippocampus
-
Bronzetti E, Felici L, Ferrante F and Valsecchi B (1992) Effect of ethylcholine mustard aziridinium (AF64A) and of the monoamine oxidase-B-inhibitor L-deprenyl on the morphology of the rat hippocampus. Int J Tissue React XIV:175-182.
-
(1992)
Int J Tissue React
, vol.14
, pp. 175-182
-
-
Bronzetti, E.1
Felici, L.2
Ferrante, F.3
Valsecchi, B.4
-
7
-
-
0028212032
-
The effect of a long-term (6 months) treatment with (-)deprenyl on antioxidant enzyme activities in selective brain regions in old female Fischer 344 rats
-
Carrillo MC, Kitani K, Kanai S, Sato Y, Miyasaka K and Ivy GO (1994a) The effect of a long-term (6 months) treatment with (-)deprenyl on antioxidant enzyme activities in selective brain regions in old female Fischer 344 rats. Biochem Pharmacol 47:1333-1338.
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 1333-1338
-
-
Carrillo, M.C.1
Kitani, K.2
Kanai, S.3
Sato, Y.4
Miyasaka, K.5
Ivy, G.O.6
-
8
-
-
0028175742
-
(-)Deprenyl increases activities of Superoxide dismutase and catalase in certain brain regions in old male mice
-
Carrillo MC, Kitani K, Kanai S, Sato Y, Miyasaka K and Ivy GO (1994b) (-)Deprenyl increases activities of Superoxide dismutase and catalase in certain brain regions in old male mice. Life Sci 54:975-981.
-
(1994)
Life Sci
, vol.54
, pp. 975-981
-
-
Carrillo, M.C.1
Kitani, K.2
Kanai, S.3
Sato, Y.4
Miyasaka, K.5
Ivy, G.O.6
-
9
-
-
0028181102
-
(-)-Deprenyl increases activities of superoxide dismutase (SOD) in striatum of dog brain
-
Carrillo MC, Ivy GO, Milgram NW, Head E, Wu P and Kitani K (1994c) (-)-Deprenyl increases activities of superoxide dismutase (SOD) in striatum of dog brain. Life Sci 54:1483-1489.
-
(1994)
Life Sci
, vol.54
, pp. 1483-1489
-
-
Carrillo, M.C.1
Ivy, G.O.2
Milgram, N.W.3
Head, E.4
Wu, P.5
Kitani, K.6
-
10
-
-
0028182741
-
Suppression of hydroxyl radical formation by MAO inhibitors: A novel possible neuroprotective mechanism in dopaminergic neurotoxicity
-
Chiueh CC, Huang S-J and Murphy DL (1994) Suppression of hydroxyl radical formation by MAO inhibitors: A novel possible neuroprotective mechanism in dopaminergic neurotoxicity. J Neural Trans 41(Suppl.) :189-196.
-
(1994)
J Neural Trans
, vol.41
, Issue.SUPPL.
, pp. 189-196
-
-
Chiueh, C.C.1
Huang, S.-J.2
Murphy, D.L.3
-
11
-
-
0021009820
-
The pathobiology of Parkinson's disease: Biochemical aspects of dopamine neuron senescence
-
Cohen G (1983) The pathobiology of Parkinson's disease: Biochemical aspects of dopamine neuron senescence. J Neural Transm 19(Suppl.):89-103.
-
(1983)
J Neural Transm
, vol.19
, Issue.SUPPL.
, pp. 89-103
-
-
Cohen, G.1
-
12
-
-
0028091176
-
Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease
-
Dexter DT, Sian J, Rose S, Hindmarsh JG, Mann VM, Cooper JM, Wells FR, Daniel SE, Lees AJ, Schapira MD, Jenner P and Marsden CD (1994) Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease. Ann Neurol 35:38-44.
-
(1994)
Ann Neurol
, vol.35
, pp. 38-44
-
-
Dexter, D.T.1
Sian, J.2
Rose, S.3
Hindmarsh, J.G.4
Mann, V.M.5
Cooper, J.M.6
Wells, F.R.7
Daniel, S.E.8
Lees, A.J.9
Schapira, M.D.10
Jenner, P.11
Marsden, C.D.12
-
13
-
-
0028176919
-
Effect of L-deprenyl, its structural analogs and some monoamine oxidase inhibitors on dopamine uptake
-
Fang J and Yu PH (1994) Effect of L-deprenyl, its structural analogs and some monoamine oxidase inhibitors on dopamine uptake. Neuropharmacol 33:763-768.
-
(1994)
Neuropharmacol
, vol.33
, pp. 763-768
-
-
Fang, J.1
Yu, P.H.2
-
14
-
-
0025171524
-
Protection against DSP-4 induced neurotoxicity by deprenyl is not related to its inhibition of MAO B
-
Finnegan KT, Skratt JJ, Irwin I, DeLanney LE and Langston JW (1990) Protection against DSP-4 induced neurotoxicity by deprenyl is not related to its inhibition of MAO B. Eur J Pharmacol 184:119-126.
-
(1990)
Eur J Pharmacol
, vol.184
, pp. 119-126
-
-
Finnegan, K.T.1
Skratt, J.J.2
Irwin, I.3
DeLanney, L.E.4
Langston, J.W.5
-
15
-
-
0022542218
-
In vivo labeling and axonal transport of monoamine oxidase in the rat basal ganglia using radioactive pargyline
-
Gramsbergen JBP, Sebens JB and Korf J (1986) In vivo labeling and axonal transport of monoamine oxidase in the rat basal ganglia using radioactive pargyline. J Neural Transm 66:21-36.
-
(1986)
J Neural Transm
, vol.66
, pp. 21-36
-
-
Gramsbergen, J.B.P.1
Sebens, J.B.2
Korf, J.3
-
16
-
-
0018666729
-
Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
-
Griffith OW and Meister A (1979) Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J Biol Chem 254:7558-7560.
-
(1979)
J Biol Chem
, vol.254
, pp. 7558-7560
-
-
Griffith, O.W.1
Meister, A.2
-
17
-
-
15144342953
-
The neuroprotective effect of selegiline and its metabolites against DSP-4 is caused without connection to MAO-B inhibition
-
Haapalinna A, MacDonald E, Nyman L and Heinonen E (1997) The neuroprotective effect of selegiline and its metabolites against DSP-4 is caused without connection to MAO-B inhibition. Mou Disord 12(Suppl. 1):P136.
-
(1997)
Mou Disord
, vol.12
, Issue.1 SUPPL.
-
-
Haapalinna, A.1
MacDonald, E.2
Nyman, L.3
Heinonen, E.4
-
18
-
-
0030879007
-
Desmethylselegiline, a metabolite of selegiline, is an irreversible inhibitor of monoamine oxidase B in humans
-
Heinonen EH, Antilla MI, Karnani HL, Nyman LM, Vuorinen JA, Pyykkö KA and Lammintausta RAS (1997) Desmethylselegiline, a metabolite of selegiline, is an irreversible inhibitor of monoamine oxidase B in humans. J Clin Pharmacol 37:602-609.
-
(1997)
J Clin Pharmacol
, vol.37
, pp. 602-609
-
-
Heinonen, E.H.1
Antilla, M.I.2
Karnani, H.L.3
Nyman, L.M.4
Vuorinen, J.A.5
Pyykkö, K.A.6
Lammintausta, R.A.S.7
-
19
-
-
0028577499
-
Pharmacokinetic aspects of 1-deprenyl (selegiline) and its metabolites
-
Heinonen EH, Antilla MI and Lammintausta RA (1994) Pharmacokinetic aspects of 1-deprenyl (selegiline) and its metabolites. Clin Pharmacol Ther 56:742-749.
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 742-749
-
-
Heinonen, E.H.1
Antilla, M.I.2
Lammintausta, R.A.3
-
20
-
-
0025971259
-
Glutathione deficiency leads to mitochondrial damage in brain
-
Jain A, Mårtensson J, Stole E, Auld PAM and Meister A (1991) Glutathione deficiency leads to mitochondrial damage in brain. Proc Natl Acad Sci USA 88:1913-1917.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 1913-1917
-
-
Jain, A.1
Mårtensson, J.2
Stole, E.3
Auld, P.A.M.4
Meister, A.5
-
21
-
-
0029751104
-
Oxidative stress in the pathogenesis of Parkinson's disease
-
Jenner P and Olanow CW (1996) Oxidative stress in the pathogenesis of Parkinson's disease. Neurology 47:161-170.
-
(1996)
Neurology
, vol.47
, pp. 161-170
-
-
Jenner, P.1
Olanow, C.W.2
-
22
-
-
0018128143
-
The possible mechanism of action of (-)-deprenyl in Parkinson's disease
-
Knoll J (1978) The possible mechanism of action of (-)-deprenyl in Parkinson's disease. J Neural Transm 43:177-198.
-
(1978)
J Neural Transm
, vol.43
, pp. 177-198
-
-
Knoll, J.1
-
23
-
-
0015274536
-
Some puzzling pharmacological effects of monoamine oxidase inhibitors
-
Knoll J and Magyar K (1972) Some puzzling pharmacological effects of monoamine oxidase inhibitors. Adv Biochem Psychopharmacol 5:393-408.
-
(1972)
Adv Biochem Psychopharmacol
, vol.5
, pp. 393-408
-
-
Knoll, J.1
Magyar, K.2
-
24
-
-
0028982658
-
L-Deprenyl reduces brain damage in rats exposed to transient hypoxia-ischemia
-
Knollema S, Aukema W, Hom H, Korf J and Ter Horst JG (1995) L-Deprenyl reduces brain damage in rats exposed to transient hypoxia-ischemia. Stroke 26:1883-1887.
-
(1995)
Stroke
, vol.26
, pp. 1883-1887
-
-
Knollema, S.1
Aukema, W.2
Hom, H.3
Korf, J.4
Ter Horst, J.G.5
-
25
-
-
0030582079
-
Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylpyridinium
-
Koutsilieri E, Chen T-S, Rausch W-D and Riederer P (1996) Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylpyridinium. Eur J Pharmacol 306:181-186.
-
(1996)
Eur J Pharmacol
, vol.306
, pp. 181-186
-
-
Koutsilieri, E.1
Chen, T.-S.2
Rausch, W.-D.3
Riederer, P.4
-
26
-
-
0029925613
-
Selegiline and lymphocyte superoxide dismutase activities in Parkinson's disease
-
Kushleika J, Checkoway H, Woods JS, Moon J-D, Smith-Weller T, Franklin GM and Swanson PD (1996) Selegiline and lymphocyte superoxide dismutase activities in Parkinson's disease. Ann Neurol 39:378-381.
-
(1996)
Ann Neurol
, vol.39
, pp. 378-381
-
-
Kushleika, J.1
Checkoway, H.2
Woods, J.S.3
Moon, J.-D.4
Smith-Weller, T.5
Franklin, G.M.6
Swanson, P.D.7
-
28
-
-
0026004832
-
Inhibition of glutathione synthesis in the newborn rat: A model of endogenously produced oxidative stress
-
Mårtensson J, Jain A, Stole E, Frayer W, Auld PA and Meister A (1991) Inhibition of glutathione synthesis in the newborn rat: A model of endogenously produced oxidative stress. Proc Natl Acad Sci USA 88:9360-9364.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 9360-9364
-
-
Mårtensson, J.1
Jain, A.2
Stole, E.3
Frayer, W.4
Auld, P.A.5
Meister, A.6
-
29
-
-
0025754161
-
Glutathione deficiency decreases tissue ascorbate levels in newborn rats: Ascorbate spares glutathione and protects
-
Mårtensson J and Meister A (1991) Glutathione deficiency decreases tissue ascorbate levels in newborn rats: Ascorbate spares glutathione and protects. Proc Natl Acad Sci USA 88:4656-4660.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4656-4660
-
-
Mårtensson, J.1
Meister, A.2
-
30
-
-
0026343403
-
Glutathione deficiency produce by inhibition of its synthesis, and its reversal; applications in research and therapy
-
Meister A (1991) Glutathione deficiency produce by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacol Ther 51:155-194.
-
(1991)
Pharmacol Ther
, vol.51
, pp. 155-194
-
-
Meister, A.1
-
32
-
-
0022394212
-
Deprenyl protects dopaminergic neurons from the neurotoxic effects of 1-methyl-4-phenylpyridinium ion
-
Mytilineou C and Cohen G (1985) Deprenyl protects dopaminergic neurons from the neurotoxic effects of 1-methyl-4-phenylpyridinium ion. J Neurochem 45:1951-1953.
-
(1985)
J Neurochem
, vol.45
, pp. 1951-1953
-
-
Mytilineou, C.1
Cohen, G.2
-
33
-
-
0027362832
-
Toxic and protective effects of L-DOPA on mesencephalic cell cultures
-
Mytilineou C, Han SK and Cohen G (1993) Toxic and protective effects of L-DOPA on mesencephalic cell cultures. J Neurochem 61:1470-1478.
-
(1993)
J Neurochem
, vol.61
, pp. 1470-1478
-
-
Mytilineou, C.1
Han, S.K.2
Cohen, G.3
-
34
-
-
0031020650
-
L-Deprenyl protects mesencephalic dopamine neurons from glutamate receptor-mediated toxicity in vitro
-
Mytilineou C, Radcliffe P, Leonardi Kokotos E, Werner P and Olanow WC (1997a) L-Deprenyl protects mesencephalic dopamine neurons from glutamate receptor-mediated toxicity in vitro. J Neurochem 68:33-39.
-
(1997)
J Neurochem
, vol.68
, pp. 33-39
-
-
Mytilineou, C.1
Radcliffe, P.2
Leonardi Kokotos, E.3
Werner, P.4
Olanow, W.C.5
-
35
-
-
0031037786
-
L-(-)-Desmethylselegiline, a metabolite of selegiline, protects mesencephalic dopamine neurons from excitotoxicity in vitro
-
Mytilineou C, Radcliffe PM and Olanow CW (1997b) L-(-)-Desmethylselegiline, a metabolite of selegiline, protects mesencephalic dopamine neurons from excitotoxicity in vitro. J Neurochem 68:434-436.
-
(1997)
J Neurochem
, vol.68
, pp. 434-436
-
-
Mytilineou, C.1
Radcliffe, P.M.2
Olanow, C.W.3
-
36
-
-
0015270743
-
Neuronal monoamine oxidase: Specific enzyme types and their rates of formation
-
Costa E and Sandler M, eds Raven Press, New York
-
Neff NH and Goridis C (1972) Neuronal monoamine oxidase: Specific enzyme types and their rates of formation, in Monoamine Oxidases: New Vistas (Costa E and Sandler M, eds) pp 307-323, Raven Press, New York.
-
(1972)
Monoamine Oxidases: New Vistas
, pp. 307-323
-
-
Neff, N.H.1
Goridis, C.2
-
37
-
-
0026841329
-
Does selegiline monotherapy in Parkinson's disease act by symptomatic or protective mechanisms?
-
Olanow CW and Calne D (1992) Does selegiline monotherapy in Parkinson's disease act by symptomatic or protective mechanisms? Neurology 42:13-26.
-
(1992)
Neurology
, vol.42
, pp. 13-26
-
-
Olanow, C.W.1
Calne, D.2
-
38
-
-
0028858370
-
The effect of deprenyl and levodopa on the progression of Parkinson's disease
-
Olanow CW, Hauser RA, Gauger L, Malapira T, Koller W and Hubble J (1995) The effect of deprenyl and levodopa on the progression of Parkinson's disease. Ann Neurol 38:771-777.
-
(1995)
Ann Neurol
, vol.38
, pp. 771-777
-
-
Olanow, C.W.1
Hauser, R.A.2
Gauger, L.3
Malapira, T.4
Koller, W.5
Hubble, J.6
-
39
-
-
0024456653
-
Effect of deprenyl on the progression of disability in early Parkinson's disease
-
Parkinson Study Group (1989) Effect of deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med 321:1364-1371.
-
(1989)
N Engl J Med
, vol.321
, pp. 1364-1371
-
-
-
40
-
-
0027530638
-
Effect of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
-
Parkinson Study Group (1993) Effect of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med 328:176-183.
-
(1993)
N Engl J Med
, vol.328
, pp. 176-183
-
-
-
41
-
-
0024537271
-
Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depletion action of 6-hydroxydopamine in rat striatum
-
Pileblad E, Magnusson T and Fornstedt B (1989) Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depletion action of 6-hydroxydopamine in rat striatum. J Neurochem 52:978-980.
-
(1989)
J Neurochem
, vol.52
, pp. 978-980
-
-
Pileblad, E.1
Magnusson, T.2
Fornstedt, B.3
-
42
-
-
0024557734
-
Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains
-
Riederer P, Sofic E, Rausch W-D, Schmidt B, Reynolds GP, Jellinger K and Youdim MBH (1989) Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains. J Neurochem 52:515-520.
-
(1989)
J Neurochem
, vol.52
, pp. 515-520
-
-
Riederer, P.1
Sofic, E.2
Rausch, W.-D.3
Schmidt, B.4
Reynolds, G.P.5
Jellinger, K.6
Youdim, M.B.H.7
-
43
-
-
0027292598
-
L-Deprenyl increases survival of rat foetal nigral neurones in culture
-
Roy E and Bedard PJ (1993) L-Deprenyl increases survival of rat foetal nigral neurones in culture. NeuroReport 4:1183-1186.
-
(1993)
NeuroReport
, vol.4
, pp. 1183-1186
-
-
Roy, E.1
Bedard, P.J.2
-
44
-
-
0026514670
-
L-Deprenyl reduces the death of motoneurons caused by axotomy
-
Salo PT and Tatton WG (1992) L-Deprenyl reduces the death of motoneurons caused by axotomy. J Neurosci Res 31:394-400.
-
(1992)
J Neurosci Res
, vol.31
, pp. 394-400
-
-
Salo, P.T.1
Tatton, W.G.2
-
45
-
-
0029876906
-
Monoamine oxidase B inhibitor selegiline protects young and aged rat peripheral sympathetic neurons against 6-hydroxydopamine-induced neurotoxicity
-
Salonen T, Haapalinna A, Heinonen E, Suhonen J and Hervonen A (1996) Monoamine oxidase B inhibitor selegiline protects young and aged rat peripheral sympathetic neurons against 6-hydroxydopamine-induced neurotoxicity. Acta Neuropathol 91:466-474.
-
(1996)
Acta Neuropathol
, vol.91
, pp. 466-474
-
-
Salonen, T.1
Haapalinna, A.2
Heinonen, E.3
Suhonen, J.4
Hervonen, A.5
-
46
-
-
0026469784
-
The antiparkinson efficacy of deprenyl derives from transient improvement that is likely to be symptomatic
-
Schulzer M, Mak E and Calne DB (1992) The antiparkinson efficacy of deprenyl derives from transient improvement that is likely to be symptomatic. Ann Neurol 32:795-798.
-
(1992)
Ann Neurol
, vol.32
, pp. 795-798
-
-
Schulzer, M.1
Mak, E.2
Calne, D.B.3
-
47
-
-
0028075410
-
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
-
Sian J, Dexter DT, Lees AJ, Daniel S, Agid Y, Javoy-Agid F, Jenner P and Marsden CD (1994) Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol 36:348-355.
-
(1994)
Ann Neurol
, vol.36
, pp. 348-355
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Agid, Y.5
Javoy-Agid, F.6
Jenner, P.7
Marsden, C.D.8
-
48
-
-
0011823687
-
Effect of selegiline on the hippocampal CA1 layer following transient ischemia in gerbil
-
Sivenius J, Kuhmonen J, Miettinen R, Haapalinna A and Riekkinen P Jr (1994) Effect of selegiline on the hippocampal CA1 layer following transient ischemia in gerbil. Soc Neurosci Abstr 20:83.5.
-
(1994)
Soc Neurosci Abstr
, vol.20
, pp. 835
-
-
Sivenius, J.1
Kuhmonen, J.2
Miettinen, R.3
Haapalinna, A.4
Riekkinen Jr., P.5
-
49
-
-
0021889191
-
Tyramine pressor sensitivity changes during deprenyl treatment
-
Sunderland T, Mueller EA, Cohen RM, Jimerson DC, Pickar D and Murphy DL (1985) Tyramine pressor sensitivity changes during deprenyl treatment. Psychopharmacology 86:432-437.
-
(1985)
Psychopharmacology
, vol.86
, pp. 432-437
-
-
Sunderland, T.1
Mueller, E.A.2
Cohen, R.M.3
Jimerson, D.C.4
Pickar, D.5
Murphy, D.L.6
-
50
-
-
0028182782
-
Amphetamine-metabolites of deprenyl involved in protection against neurotoxicity induced by MPTP and 2′-methyl-MPTP
-
Sziráki I, Kardos V, Patthy M, Pátfalusi M, Gaál J, Solti M, Kollár E and Singer J (1994) Amphetamine-metabolites of deprenyl involved in protection against neurotoxicity induced by MPTP and 2′-methyl-MPTP. J Neural Transm 47(Suppl.): 207-219.
-
(1994)
J Neural Transm
, vol.47
, Issue.SUPPL.
, pp. 207-219
-
-
Sziráki, I.1
Kardos, V.2
Patthy, M.3
Pátfalusi, M.4
Gaál, J.5
Solti, M.6
Kollár, E.7
Singer, J.8
-
51
-
-
0029731378
-
Modulation of gene expression rather than monoamine oxidase inhibition: (-)-Deprenyl-related compounds in controlling neurodegeneration
-
Tatton WG and Chalmers-Redman RME (1996) Modulation of gene expression rather than monoamine oxidase inhibition: (-)-Deprenyl-related compounds in controlling neurodegeneration. Neurology 47(Suppl. 3):171-183.
-
(1996)
Neurology
, vol.47
, Issue.3 SUPPL.
, pp. 171-183
-
-
Tatton, W.G.1
Chalmers-Redman, R.M.E.2
-
52
-
-
0026353406
-
Rescue of dying neurons: A new action for L-deprenyl in MPTP parkinsonism
-
Tatton WG and Greenwood CE (1991) Rescue of dying neurons: A new action for L-deprenyl in MPTP parkinsonism. J Neurosci Res 30:666-672.
-
(1991)
J Neurosci Res
, vol.30
, pp. 666-672
-
-
Tatton, W.G.1
Greenwood, C.E.2
-
53
-
-
0027941312
-
(-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis
-
Tatton WG, Ju WYL, Holland DP, Tai C and Kwan M (1994) (-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis. J Neurochem 63:1572-1575.
-
(1994)
J Neurochem
, vol.63
, pp. 1572-1575
-
-
Tatton, W.G.1
Ju, W.Y.L.2
Holland, D.P.3
Tai, C.4
Kwan, M.5
-
54
-
-
0024343466
-
The effect of deprenyl (selegiline) on the natural history of Parkinson's disease
-
Tetrud JW and Langsten JW (1989) The effect of deprenyl (selegiline) on the natural history of Parkinson's disease. Science 245:519-522.
-
(1989)
Science
, vol.245
, pp. 519-522
-
-
Tetrud, J.W.1
Langsten, J.W.2
-
55
-
-
0028971624
-
Effect of MPTP and L-deprenyl on antioxidant enzymes and lipid peroxidation levels in mouse brain
-
Thiffault C, Aumont N, Quirion R and Poirier J (1995) Effect of MPTP and L-deprenyl on antioxidant enzymes and lipid peroxidation levels in mouse brain. J Neurochem 65:2725-2733.
-
(1995)
J Neurochem
, vol.65
, pp. 2725-2733
-
-
Thiffault, C.1
Aumont, N.2
Quirion, R.3
Poirier, J.4
-
56
-
-
0031019340
-
Hydroxyl and peroxyl radical trapping by the monoamine oxidase-B inhibitors deprenyl and MDL 72,974A: Implications for protection of biological amines
-
Thomas CE, Huber EW and Ohlweiler DF (1997) Hydroxyl and peroxyl radical trapping by the monoamine oxidase-B inhibitors deprenyl and MDL 72,974A: Implications for protection of biological amines. Free Rad Biol Med 22:733-737.
-
(1997)
Free Rad Biol Med
, vol.22
, pp. 733-737
-
-
Thomas, C.E.1
Huber, E.W.2
Ohlweiler, D.F.3
-
57
-
-
0014481378
-
Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
-
Tietze F (1969) Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues. Anal Biochem 27:502-522.
-
(1969)
Anal Biochem
, vol.27
, pp. 502-522
-
-
Tietze, F.1
-
59
-
-
0029949789
-
+ toxicity in nigral dopaminergic neurons
-
+ toxicity in nigral dopaminergic neurons. NeuroReport 7:921-923.
-
(1996)
NeuroReport
, vol.7
, pp. 921-923
-
-
Wüllner, U.1
Löschmann, P.-A.2
Schulz, J.B.3
Schmidt, A.4
Dringen, R.5
Eblen, F.6
Turski, L.7
Klockgether, T.8
-
60
-
-
0022638352
-
Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: Relationship of metabolism to MAO-B inhibitory activity
-
Yoshida T, Yamada Y, Yamamoto T and Kuroiwa Y (1986) Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: Relationship of metabolism to MAO-B inhibitory activity. Xenobiotica 16:129-136.
-
(1986)
Xenobiotica
, vol.16
, pp. 129-136
-
-
Yoshida, T.1
Yamada, Y.2
Yamamoto, T.3
Kuroiwa, Y.4
-
61
-
-
0031025395
-
Energy stress-induced dopamine loss in glutathione peroxidase-overexpressing transgenic mice and in glutathione-depleted mesencephalic cultures
-
Zeevalk GD, Bernard LP, Albers DS, Mirochnitchenko O, Nicklas WJ and Sonsalla PK (1997) Energy stress-induced dopamine loss in glutathione peroxidase-overexpressing transgenic mice and in glutathione-depleted mesencephalic cultures. J Neurochem 68:426-429.
-
(1997)
J Neurochem
, vol.68
, pp. 426-429
-
-
Zeevalk, G.D.1
Bernard, L.P.2
Albers, D.S.3
Mirochnitchenko, O.4
Nicklas, W.J.5
Sonsalla, P.K.6
-
62
-
-
0027318190
-
Bcl-2 inhibits death of central neural cells induced by multiple agents
-
Zhong L-T, Sarafinn T, Kane DJ, Charles AC, Mah SP, Edwards RH and Bredesen DE (1993) Bcl-2 inhibits death of central neural cells induced by multiple agents. Proc Nat Acad Sci USA 90:4533-4537.
-
(1993)
Proc Nat Acad Sci USA
, vol.90
, pp. 4533-4537
-
-
Zhong, L.-T.1
Sarafinn, T.2
Kane, D.J.3
Charles, A.C.4
Mah, S.P.5
Edwards, R.H.6
Bredesen, D.E.7
-
63
-
-
0022495911
-
The effect of repeated doses of (-)-deprenyl on the dynamics of monoaminergic transmission. Comparison with clorgyline
-
Zsilla G, Földi P, Held G, Székely AM and Knoll J (1986) The effect of repeated doses of (-)-deprenyl on the dynamics of monoaminergic transmission. Comparison with clorgyline. Pol J Pharmacol Pharm 38:57-67.
-
(1986)
Pol J Pharmacol Pharm
, vol.38
, pp. 57-67
-
-
Zsilla, G.1
Földi, P.2
Held, G.3
Székely, A.M.4
Knoll, J.5
|