Aggresome formation in liver cells in response to different toxic mechanisms: Role of the ubiquitin-proteasome pathway and the frameshift mutant of ubiquitin

Experimental and Molecular Pathology

Volumn 71, Issue 3, 2001, Pages 241-246

  French, Barbara A ^a   Van Leeuwen, Fred ^d   Riley, Nora E ^a   Yuan, Qi X ^a   Bardag Gorce, Fawzia ^a   Gaal, Karl ^c   Lue, Yan He ^a   Marceau, Norman ^b   French, Samuel W ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b UNIVERSITÉ LAVAL   (Canada)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^d NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; COLCHICINE; GALACTOSAMINE; OKADAIC ACID; PROTEASOME; PROTEASOME INHIBITOR; TAUTOMYCIN; THIOACETAMIDE; UBIQUITIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONFOCAL MICROSCOPY; FRAMESHIFT MUTATION; IMMUNOFLUORESCENCE MICROSCOPY; LIVER CELL; LIVER DISEASE; LIVER INJURY; MALE; MALLORY BODY; MOUSE; NONHUMAN; PATHOGENESIS; SIGNAL TRANSDUCTION; THERMAL EXPOSURE;

EID: 0035680611     PISSN: 00144800     EISSN: None     Source Type: Journal    
DOI: 10.1006/exmp.2001.2401     Document Type: Article

References (38)

1. Proteasome inhibitors: A novel class of potent and effective antitumor agents
2. Intracellular localization on proteasomal degradation of a viral antigen
3. The role of the ubiquitin-proteasome pathway in Mallory body formation. An immunohistochemical study
4. Nuclear factor-KB. A pivotal transcription factor in chronic inflammatory diseases
5. Selective accumulation of IF proteins at a focal juxtanuclear site in COS-1 cells transfected with mouse keratin 18 cDNA
6. Aggresome formation by anti-Ras intracellular scFu fragments. The fate of the antigen-antibody complex
7. Conformational disease
8. Biologically active products of stimulated liver macrophages (Kupffer cells)
9. Colchicine-induced Mallory body formation in the mouse
10. Relationship between genomic DNA ploidy and parameters of liver damage during necrosis and regeneration induced by thioacetamide
11. Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF T cells treated with calyculin-A, okadaic acid and tautomycin
12. A new inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (20S proteasome) induces accumulation of ubiquitin-protein conjugates in a neural cell
13. Experimental Mallory body formation: In drug induced cytokeratin aggregation
14. Characterization and dynamics of aggresome formation by cytosolic GFP-chimera
15. Aggresomes: A cellular response to misfolded proteins
16. Biosynthesis of surfactant protein C: Characterization of aggresome formation by EGFP chimers containing propeptide mutants lacking conserved cysteine residues
17. Molecular structure changes in Mallory body protein in human and mouse livers: An infrared spectroscopy study
18. Selective rearrangement of cytokeratin filaments in cultured liver epithelium cells induced by nickel
19. Conformational disease
20. Inhibition of the ubiquitin-proteasome system in Alzheimer's disease
21. Frameshift mutant of ubiquitin-B in Mallory body formation in human liver
22. PMP22 accumulation in aggresomes: Implications for CMTIA pathology
23. Ubiquitin is present on the cytokeratin intermediate filaments and Mallory bodies of hepatocytes
24. Mechanisms of oxidative stress-induced acute tissue injury
25. Frameshift mutants of β amyloid processor protein and ubiquitin-B in Alzheimer's and Down' patients
26. Molecular misreading: A new type of transcript mutation expressed during aging
27. Intracellular transport, assembly and degradation of wild type and diseased-linked mutant gap junction proteins
28. Dynamic association of proteasome machinery with the centrosome
29. On the spatial organization ubiquitin-dependent proteolysis in HeLa cells
30. Ubiquitin-mediated proteolysis centers in HeLa cells: Indication from studies of an inhibitor of the chymotrypsin-like activity of the proteasome
31. Role of the proteasome in Mallory body formation in drug primed mice
32. Tautomycin induces extensive Mallory body formation in drug primed mouse livers
33. Heat shock in vivo induces Mallory body formation in drug primed mouse liver
34. Mallory body induction in drug primed mouse liver
35. Ethanol okadaic acid and D-galactosamine induced Mallory bodies in drug primed mice: Role of NF-KB
36. Mechanisms of Mallory body formation induced by okadaic acid in drug primed mice
37. Effect of ethanol and thioacetamide on Mallory body and tumor formation in drug-primed mouse liver
38. Alcohol induces Mallory body formation in drug primed mice