-
1
-
-
0028895654
-
Modular binding domains in signal transduction proteins
-
Cohen, G. B., Ren, R. & Baltimore, D. (1995). Modular binding domains in signal transduction proteins. Cell, 80, 237-248.
-
(1995)
Cell
, vol.80
, pp. 237-248
-
-
Cohen, G.B.1
Ren, R.2
Baltimore, D.3
-
2
-
-
0036143825
-
Domain alternation switches B(12)-dependent methionine synthase to the activation conformation
-
Bandarian, V., Pattridge, K. A., Lennon, B. W., Huddler, D. P., Matthews, R. G. & Ludwig, M. L. (2002). Domain alternation switches B(12)-dependent methionine synthase to the activation conformation. Nature Struct. Biol. 9, 53-56.
-
(2002)
Nature Struct. Biol.
, vol.9
, pp. 53-56
-
-
Bandarian, V.1
Pattridge, K.A.2
Lennon, B.W.3
Huddler, D.P.4
Matthews, R.G.5
Ludwig, M.L.6
-
3
-
-
0032560616
-
Carbamoyl phosphate synthetase: Caught in the act of glutamine hydrolysis
-
Thoden, J. B., Miran, S. G., Phillips, J. C., Howard, A. J., Raushel, F. M. & Holden, H. M. (1998). Carbamoyl phosphate synthetase: Caught in the act of glutamine hydrolysis. Biochemistry, 37, 8825-8831.
-
(1998)
Biochemistry
, vol.37
, pp. 8825-8831
-
-
Thoden, J.B.1
Miran, S.G.2
Phillips, J.C.3
Howard, A.J.4
Raushel, F.M.5
Holden, H.M.6
-
4
-
-
0034887171
-
Polyketide biosynthesis: A millennium review
-
Staunton, J. & Weissman, K. J. (2001). Polyketide biosynthesis: A millennium review. Nature Prod. Rep. 18, 380-416.
-
(2001)
Nature Prod. Rep.
, vol.18
, pp. 380-416
-
-
Staunton, J.1
Weissman, K.J.2
-
5
-
-
9444278428
-
Modular peptide synthetases involved in nonribosomal peptide synthesis
-
Marahiel, M. A., Stachelhaus, T. & Mootz, H. D. (1997). Modular peptide synthetases involved in nonribosomal peptide synthesis. Chem. Rev. 97, 2651-2674.
-
(1997)
Chem. Rev.
, vol.97
, pp. 2651-2674
-
-
Marahiel, M.A.1
Stachelhaus, T.2
Mootz, H.D.3
-
6
-
-
0001296027
-
Multifunctional peptide synthetases
-
von Dohren, H., Keller, U., Vater, J. & Zocher, R. (1997). Multifunctional peptide synthetases. Chem. Rev. 97, 2675-2706.
-
(1997)
Chem. Rev.
, vol.97
, pp. 2675-2706
-
-
Von Dohren, H.1
Keller, U.2
Vater, J.3
Zocher, R.4
-
7
-
-
0036523418
-
Combinatorial biosynthesis of antibiotics: Challenges and opportunities
-
Walsh, C. T. (2002). Combinatorial biosynthesis of antibiotics: Challenges and opportunities. ChemBioChem., 3, 124-134.
-
(2002)
ChemBioChem.
, vol.3
, pp. 124-134
-
-
Walsh, C.T.1
-
8
-
-
0034552096
-
Natural product biosynthesis: A new interface between enzymology and medicine
-
Khosla, C. (2000). Natural product biosynthesis: A new interface between enzymology and medicine. J. Org. Chem. 65, 8127-8133.
-
(2000)
J. Org. Chem.
, vol.65
, pp. 8127-8133
-
-
Khosla, C.1
-
9
-
-
0031259902
-
Structural studies of natural product biosynthetic proteins
-
Townsend, C. A. (1997). Structural studies of natural product biosynthetic proteins. Chem. Biol. 4, 721-730.
-
(1997)
Chem. Biol.
, vol.4
, pp. 721-730
-
-
Townsend, C.A.1
-
10
-
-
0037155595
-
Bioengineering. Working outside the protein-synthesis rules
-
Gewolb, J. (2002). Bioengineering. Working outside the protein-synthesis rules. Science, 295, 2205-2207.
-
(2002)
Science
, vol.295
, pp. 2205-2207
-
-
Gewolb, J.1
-
11
-
-
0021112860
-
The architecture of the animal fatty acid synthetase. I. Proteolytic dissection and peptide mapping
-
Mattick, J. S., Tsukamoto, Y., Nickless, J. & Wakil, S. J. (1983). The architecture of the animal fatty acid synthetase. I. Proteolytic dissection and peptide mapping. J. Biol. Chem. 258, 15291-15299.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 15291-15299
-
-
Mattick, J.S.1
Tsukamoto, Y.2
Nickless, J.3
Wakil, S.J.4
-
12
-
-
0014708426
-
Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis
-
Klenow, H. & Hennigsen, I. (1970). Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis. Proc. Natl. Acad. Sci. USA, 65, 168.
-
(1970)
Proc. Natl. Acad. Sci. USA
, vol.65
, pp. 168
-
-
Klenow, H.1
Hennigsen, I.2
-
13
-
-
0033079834
-
Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase
-
Gokhale, R. S., Hunziker, D., Cane, D. E. & Khosla, C. (1999). Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase. Chem. Biol. 6, 117-125.
-
(1999)
Chem. Biol.
, vol.6
, pp. 117-125
-
-
Gokhale, R.S.1
Hunziker, D.2
Cane, D.E.3
Khosla, C.4
-
14
-
-
0036008847
-
Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae
-
Yoon, Y. J., Beck, B. J., Kim, B. S., Kang, H. Y., Reynolds, K. A. & Sherman, D. H. (2002). Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae. Chem. Biol. 9, 203-214.
-
(2002)
Chem. Biol.
, vol.9
, pp. 203-214
-
-
Yoon, Y.J.1
Beck, B.J.2
Kim, B.S.3
Kang, H.Y.4
Reynolds, K.A.5
Sherman, D.H.6
-
15
-
-
0035957047
-
Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules
-
Tsuji, S. Y., Cane, D. E. & Khosla, C. (2001). Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules. Biochemistry, 40, 2326-2331.
-
(2001)
Biochemistry
, vol.40
, pp. 2326-2331
-
-
Tsuji, S.Y.1
Cane, D.E.2
Khosla, C.3
-
16
-
-
0034730091
-
Control of directionality in nonribosomal peptide synthesis: Role of the condensation domain in preventing misinitiation and timing of epimerization
-
Linne, U. & Marahiel, M. A. (2000). Control of directionality in nonribosomal peptide synthesis: Role of the condensation domain in preventing misinitiation and timing of epimerization. Biochemistry, 39, 10439-10447.
-
(2000)
Biochemistry
, vol.39
, pp. 10439-10447
-
-
Linne, U.1
Marahiel, M.A.2
-
17
-
-
0035853039
-
Human fatty acid synthase: Role of inter-domain in the formation of catalytically active synthase dimer
-
Chirala, S. S., Jayakumar, A., Gu, Z. W. & Wakil, S. J. (2001). Human fatty acid synthase: Role of inter-domain in the formation of catalytically active synthase dimer. Proc. Natl. Acad. Sci. USA, 98, 3104-3108.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3104-3108
-
-
Chirala, S.S.1
Jayakumar, A.2
Gu, Z.W.3
Wakil, S.J.4
-
18
-
-
0025024567
-
Nonribosomal biosynthesis of peptide antibiotics
-
Kleinkauf, H. & von Dohren, H. (1990). Nonribosomal biosynthesis of peptide antibiotics. Eur. J. Biochem. 192, 1-15.
-
(1990)
Eur. J. Biochem.
, vol.192
, pp. 1-15
-
-
Kleinkauf, H.1
Von Dohren, H.2
-
19
-
-
0035156443
-
Exploring the domain structure of modular nonribosomal peptide synthetases
-
Weber, T. & Marahiel, M. A. (2001). Exploring the domain structure of modular nonribosomal peptide synthetases. Structure, 9, R3-R9.
-
(2001)
Structure
, vol.9
-
-
Weber, T.1
Marahiel, M.A.2
-
20
-
-
0030756031
-
Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S
-
Conti, E., Stachelhaus, T., Marahiel, M. A. & Brick, P. (1997). Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S. EMBO J. 16, 4174-4183.
-
(1997)
EMBO J.
, vol.16
, pp. 4174-4183
-
-
Conti, E.1
Stachelhaus, T.2
Marahiel, M.A.3
Brick, P.4
-
21
-
-
0034013269
-
Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains
-
Challis, G. L., Ravel, J. & Townsend, C. A. (2000). Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains. Chem. Biol. 7, 211-224.
-
(2000)
Chem. Biol.
, vol.7
, pp. 211-224
-
-
Challis, G.L.1
Ravel, J.2
Townsend, C.A.3
-
22
-
-
0033179468
-
The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases
-
Stachelhaus, T., Mootz, H. D. & Marahiel, M. A. (1999). The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases. Chem. Biol. 6, 493-505.
-
(1999)
Chem. Biol.
, vol.6
, pp. 493-505
-
-
Stachelhaus, T.1
Mootz, H.D.2
Marahiel, M.A.3
-
23
-
-
0035909913
-
Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel
-
Tsai, S. C., Miercke, L. J., Krucinski, J., Gokhale, R., Chen, J. C., Foster, P. G. et al. (2001). Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel. Proc. Natl. Acad. Sci. USA, 98, 14808-14813.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14808-14813
-
-
Tsai, S.C.1
Miercke, L.J.2
Krucinski, J.3
Gokhale, R.4
Chen, J.C.5
Foster, P.G.6
-
24
-
-
0030972114
-
Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2)
-
Crump, M. P., Crosby, J., Dempsey, C. E., Parkinson, J. A., Murray, M., Hopwood, D. A. & Simpson, T. J. (1997). Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2). Biochemistry, 36, 6000-6008.
-
(1997)
Biochemistry
, vol.36
, pp. 6000-6008
-
-
Crump, M.P.1
Crosby, J.2
Dempsey, C.E.3
Parkinson, J.A.4
Murray, M.5
Hopwood, D.A.6
Simpson, T.J.7
-
25
-
-
0001038483
-
Enzymology and molecular biology of aflatoxin biosynthesis
-
Minto, R. E. & Townsend, C. A. (1997). Enzymology and molecular biology of aflatoxin biosynthesis. Chem. Rev. 97, 2537-2555.
-
(1997)
Chem. Rev.
, vol.97
, pp. 2537-2555
-
-
Minto, R.E.1
Townsend, C.A.2
-
26
-
-
0019874608
-
Location of domains in globular proteins
-
Rashin, A. A. (1981). Location of domains in globular proteins. Nature, 291, 85-87.
-
(1981)
Nature
, vol.291
, pp. 85-87
-
-
Rashin, A.A.1
-
27
-
-
0023680201
-
Vectors that facilitate the expression and purification of foreign peptides in Escherichia coli by fusion to maltose-binding protein
-
di Guan, C., Li, P., Riggs, P. D. & Inouye, H. (1988). Vectors that facilitate the expression and purification of foreign peptides in Escherichia coli by fusion to maltose-binding protein. Gene, 67, 21-30.
-
(1988)
Gene
, vol.67
, pp. 21-30
-
-
Di Guan, C.1
Li, P.2
Riggs, P.D.3
Inouye, H.4
-
28
-
-
0024296676
-
Chelating peptide-immobilized metal ion affinity chromatography. A new concept in affinity chromatography for recombinant proteins
-
Smith, M. C., Furman, T. C., Ingolia, T. D. & Pidgeon, C. (1988). Chelating peptide-immobilized metal ion affinity chromatography. A new concept in affinity chromatography for recombinant proteins. J. Biol. Chem. 263, 7211-7215.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 7211-7215
-
-
Smith, M.C.1
Furman, T.C.2
Ingolia, T.D.3
Pidgeon, C.4
-
29
-
-
0025370815
-
Dominant forces in protein folding
-
Dill, K. A. (1990). Dominant forces in protein folding. Biochemistry, 29, 7133-7155.
-
(1990)
Biochemistry
, vol.29
, pp. 7133-7155
-
-
Dill, K.A.1
-
30
-
-
0026458378
-
Amino acid substitution matrices from protein blocks
-
Henikoff, S. & Henikoff, J. G. (1992). Amino acid substitution matrices from protein blocks. Proc. Natl. Acad. Sci. USA, 89, 10915-10919.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10915-10919
-
-
Henikoff, S.1
Henikoff, J.G.2
-
31
-
-
0034518144
-
Iterative sequence/secondary structure search for protein homologs: Comparison with amino acid sequence alignments and application to fold recognition in genome databases
-
Wallqvist, A., Fukunishi, Y., Murphy, L. R., Fadel, A. & Levy, R. M. (2000). Iterative sequence/secondary structure search for protein homologs: Comparison with amino acid sequence alignments and application to fold recognition in genome databases. Bioinformatics, 16, 988-1002.
-
(2000)
Bioinformatics
, vol.16
, pp. 988-1002
-
-
Wallqvist, A.1
Fukunishi, Y.2
Murphy, L.R.3
Fadel, A.4
Levy, R.M.5
-
32
-
-
0020475449
-
A simple method for displaying the hydropathic character of a protein
-
Kyte, J. & Doolittle, R. F. (1982). A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157, 105-132.
-
(1982)
J. Mol. Biol.
, vol.157
, pp. 105-132
-
-
Kyte, J.1
Doolittle, R.F.2
-
33
-
-
0027968068
-
CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
-
Thompson, J. D., Higgins, D. G. & Gibson, T. J. (1994). CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucl. Acids Res. 22, 4673-4680.
-
(1994)
Nucl. Acids Res.
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
34
-
-
0033168097
-
A comprehensive comparison of multiple sequence alignment programs
-
Thompson, J. D., Plewniak, F. & Poch, O. (1999). A comprehensive comparison of multiple sequence alignment programs. Nucl. Acids Res. 27, 2682-2690.
-
(1999)
Nucl. Acids Res.
, vol.27
, pp. 2682-2690
-
-
Thompson, J.D.1
Plewniak, F.2
Poch, O.3
-
38
-
-
0001854796
-
Cobalamin-dependent methionine synthase
-
Banerjee, R., ed., Wiley, New York
-
Matthews, R. G. (1999). Cobalamin-dependent methionine synthase. In Chemistry and Biochemistry of B12 (Banerjee, R., ed.), pp. 681-706, Wiley, New York.
-
(1999)
Chemistry and Biochemistry of B12
, pp. 681-706
-
-
Matthews, R.G.1
-
39
-
-
0027485897
-
Electrospray mass spectrometric analysis of the domains of a large enzyme: Observation of the occupied cobalamin-binding domain and redefinition of the carboxyl terminus of methionine synthase
-
Drummond, J. T., Loo, R. R. & Matthews, R. G. (1993). Electrospray mass spectrometric analysis of the domains of a large enzyme: Observation of the occupied cobalamin-binding domain and redefinition of the carboxyl terminus of methionine synthase. Biochemistry, 32, 9282-9289.
-
(1993)
Biochemistry
, vol.32
, pp. 9282-9289
-
-
Drummond, J.T.1
Loo, R.R.2
Matthews, R.G.3
-
40
-
-
0030829339
-
Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine
-
Goulding, C. W., Postigo, D. & Matthews, R. G. (1997). Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine. Biochemistry, 36, 8082-8091.
-
(1997)
Biochemistry
, vol.36
, pp. 8082-8091
-
-
Goulding, C.W.1
Postigo, D.2
Matthews, R.G.3
-
41
-
-
0028769662
-
How a protein binds B12: A 3.0 Å X-ray structure of B12-binding domains of methionine synthase
-
Drennan, C. L., Huang, S., Drummond, J. T., Matthews, R. G. & Lidwig, M. L. (1994). How a protein binds B12: A 3.0 Å X-ray structure of B12-binding domains of methionine synthase. Science, 266, 1669-1674.
-
(1994)
Science
, vol.266
, pp. 1669-1674
-
-
Drennan, C.L.1
Huang, S.2
Drummond, J.T.3
Matthews, R.G.4
Lidwig, M.L.5
-
42
-
-
0030589146
-
The structure of the C-terminal domain of methionine synthase: Presenting S-adenosylmethionine for reductive methylation of B12
-
Dixon, M. M., Huang, S., Matthews, R. G. & Ludwig, M. (1996). The structure of the C-terminal domain of methionine synthase: Presenting S-adenosylmethionine for reductive methylation of B12. Structure, 4, 1263-1275.
-
(1996)
Structure
, vol.4
, pp. 1263-1275
-
-
Dixon, M.M.1
Huang, S.2
Matthews, R.G.3
Ludwig, M.4
-
43
-
-
0003903343
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Sambrook, J., Fristch, E. & Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Sambrook, J.1
Fristch, E.2
Maniatis, T.3
-
44
-
-
0032571245
-
Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates
-
Brautigam, C. A. & Steitz, T. A. (1998). Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates. J. Mol. Biol. 277, 363-377.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 363-377
-
-
Brautigam, C.A.1
Steitz, T.A.2
-
45
-
-
0021984004
-
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP
-
Ollis, D. L., Brick, P., Hamlin, R., Xuong, N. G. & Steitz, T. A. (1985). Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP. Nature, 313, 762-766.
-
(1985)
Nature
, vol.313
, pp. 762-766
-
-
Ollis, D.L.1
Brick, P.2
Hamlin, R.3
Xuong, N.G.4
Steitz, T.A.5
-
46
-
-
0027231782
-
Structure of DNA polymerase I Klenow fragment bound to duplex DNA
-
Beese, L. S., Derbyshire, V. & Steitz, T. A. (1993). Structure of DNA polymerase I Klenow fragment bound to duplex DNA. Science, 260, 352-355.
-
(1993)
Science
, vol.260
, pp. 352-355
-
-
Beese, L.S.1
Derbyshire, V.2
Steitz, T.A.3
-
47
-
-
0032101892
-
Identification of a gene involved in the generation of 4-thiouridine in tRNA
-
Mueller, E. G., Buck, C. J., Palenchar, P. M., Barnhart, L. E. & Paulson, J. L. (1998). Identification of a gene involved in the generation of 4-thiouridine in tRNA. Nucl. Acids Res. 26, 2606-2610.
-
(1998)
Nucl. Acids Res.
, vol.26
, pp. 2606-2610
-
-
Mueller, E.G.1
Buck, C.J.2
Palenchar, P.M.3
Barnhart, L.E.4
Paulson, J.L.5
-
48
-
-
0030878532
-
Characterization of thiI, a new gene involved in thiazole biosynthesis in Salmonella typhimurium
-
Webb, E., Claas, K. & Downs, D. M. (1997). Characterization of thiI, a new gene involved in thiazole biosynthesis in Salmonella typhimurium. J. Bacteriol. 179, 4399-4402.
-
(1997)
J. Bacteriol.
, vol.179
, pp. 4399-4402
-
-
Webb, E.1
Claas, K.2
Downs, D.M.3
-
49
-
-
0034708503
-
Evidence that ThiI, an enzyme shared between thiamin and 4-thiouridine biosynthesis, may be a sulfurtransferase that proceeds through a persulfide intermediate
-
Palenchar, P. M., Buck, C. J., Cheng, H., Larson, T. J. & Mueller, E. G. (2000). Evidence that ThiI, an enzyme shared between thiamin and 4-thiouridine biosynthesis, may be a sulfurtransferase that proceeds through a persulfide intermediate. J. Biol. Chem. 275, 8283-8286.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8283-8286
-
-
Palenchar, P.M.1
Buck, C.J.2
Cheng, H.3
Larson, T.J.4
Mueller, E.G.5
-
50
-
-
0035823572
-
The role of the cysteine residues of ThiI in the generation of 4-thiouridine in tRNA
-
Mueller, E. G., Palenchar, P. M. & Buck, C. J. (2001). The role of the cysteine residues of ThiI in the generation of 4-thiouridine in tRNA. J. Biol. Chem. 276, 33588-33595.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33588-33595
-
-
Mueller, E.G.1
Palenchar, P.M.2
Buck, C.J.3
-
51
-
-
0034646676
-
Evidence for the transfer of sulfane sulfur from IscS to ThiI during the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA
-
Kambampati, R. & Lauhon, C. T. (2000). Evidence for the transfer of sulfane sulfur from IscS to ThiI during the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA. J. Biol. Chem. 275, 10727-10730.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10727-10730
-
-
Kambampati, R.1
Lauhon, C.T.2
-
52
-
-
0037039425
-
Quaternary structure of human fatty acid synthase by electron cryomicroscopy
-
Brink, J., Ludtke, S. J., Yang, C. Y., Gu, Z. W., Wakil, S. J. & Chiu, W. (2002). Quaternary structure of human fatty acid synthase by electron cryomicroscopy. Proc. Natl Acad. Sci. USA, 99, 138-143.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 138-143
-
-
Brink, J.1
Ludtke, S.J.2
Yang, C.Y.3
Gu, Z.W.4
Wakil, S.J.5
Chiu, W.6
-
53
-
-
0035845638
-
Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro
-
Rangan, V. S., Joshi, A. K. & Smith, S. (2001). Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro. Biochemistry, 40, 10792-10799.
-
(2001)
Biochemistry
, vol.40
, pp. 10792-10799
-
-
Rangan, V.S.1
Joshi, A.K.2
Smith, S.3
-
54
-
-
0021112895
-
The architecture of the animal fatty acid synthetase. II. Separation of the core and thioesterase functions and determination of the N-C orientation of the subunit
-
Mattick, J. S., Nickless, J., Mizugaki, M., Yang, C. Y., Uchiyama, S. & Wakil, S. J. (1983). The architecture of the animal fatty acid synthetase. II. Separation of the core and thioesterase functions and determination of the N-C orientation of the subunit. J. Biol. Chem. 258, 15300-15304.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 15300-15304
-
-
Mattick, J.S.1
Nickless, J.2
Mizugaki, M.3
Yang, C.Y.4
Uchiyama, S.5
Wakil, S.J.6
-
55
-
-
0021112850
-
The architecture of the animal fatty acid synthetase. III. Isolation and characterization of beta-ketoacyl reductase
-
Wong, H., Mattick, J. S. & Wakil, S. J. (1983). The architecture of the animal fatty acid synthetase. III. Isolation and characterization of beta-ketoacyl reductase. J. Biol. Chem. 258, 15305-15311.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 15305-15311
-
-
Wong, H.1
Mattick, J.S.2
Wakil, S.J.3
-
56
-
-
0021112906
-
The architecture of the animal fatty acid synthetase complex. IV. Mapping of active centers and model for the mechanism of action
-
Tsukamoto, Y., Wong, H., Mattick, J. S. & Wakil, S. J. (1983). The architecture of the animal fatty acid synthetase complex. IV. Mapping of active centers and model for the mechanism of action. J. Biol. Chem. 258, 15312-15322.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 15312-15322
-
-
Tsukamoto, Y.1
Wong, H.2
Mattick, J.S.3
Wakil, S.J.4
-
57
-
-
0030940841
-
Animal fatty acid synthase: Functional mapping and cloning and expression of the domain I constituent activities
-
Chirala, S. S., Huang, W. Y., Jayakumar, A., Sakai, K. & Wakil, S. J. (1997). Animal fatty acid synthase: Functional mapping and cloning and expression of the domain I constituent activities. Proc. Natl. Acad. Sci. USA, 94, 5588-5593.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5588-5593
-
-
Chirala, S.S.1
Huang, W.Y.2
Jayakumar, A.3
Sakai, K.4
Wakil, S.J.5
-
58
-
-
0023698950
-
Isolation and mapping of the beta-hydroxyacyl dehydratase activity of chicken liver fatty acid synthase
-
Tsukamoto, Y. & Wakil, S. J. (1988). Isolation and mapping of the beta-hydroxyacyl dehydratase activity of chicken liver fatty acid synthase. J. Biol. Chem. 263, 16225-16229.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 16225-16229
-
-
Tsukamoto, Y.1
Wakil, S.J.2
-
59
-
-
0035572966
-
Hexanoate synthase, a specialized type I fatty acid synthase in aflatoxib B1 biosynthesis
-
Hitchman, T. S., Schmidt, E. W., Trail, F., Rarick, M. D., Linz, J. E. & Townsend, C. A. (2001). Hexanoate synthase, a specialized type I fatty acid synthase in aflatoxib B1 biosynthesis. Bioorg. Chem. 29, 293-307.
-
(2001)
Bioorg. Chem.
, vol.29
, pp. 293-307
-
-
Hitchman, T.S.1
Schmidt, E.W.2
Trail, F.3
Rarick, M.D.4
Linz, J.E.5
Townsend, C.A.6
-
60
-
-
0000543572
-
Hexanoate as a starter unit in polyketide biosynthesis
-
Townsend, C. A., Christensen, S. B. & Trautwein, K. (1984). Hexanoate as a starter unit in polyketide biosynthesis. J. Am. Chem. Soc. 106, 3868-3869.
-
(1984)
J. Am. Chem. Soc.
, vol.106
, pp. 3868-3869
-
-
Townsend, C.A.1
Christensen, S.B.2
Trautwein, K.3
-
61
-
-
0032125904
-
The in vitro conversion of norsolorinic acid to aflatoxin B1. An improved method of cell-free enzyme preparation and stabilization
-
Watanabe, C. M. H. & Townsend, C. A. (1998). The in vitro conversion of norsolorinic acid to aflatoxin B1. An improved method of cell-free enzyme preparation and stabilization. J. Am. Chem. Soc. 120, 6231-6239.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 6231-6239
-
-
Watanabe, C.M.H.1
Townsend, C.A.2
-
62
-
-
0037094126
-
Synthesis of 11-hydroxyl O-methylsterigmatocystin and the role of a cytochrome P-450 in the final step of aflatoxin biosynthesis
-
Udwary, D. W., Casillas, L. K. & Townsend, C. A. (2002). Synthesis of 11-hydroxyl O-methylsterigmatocystin and the role of a cytochrome P-450 in the final step of aflatoxin biosynthesis. J. Am. Chem. Soc. 124, 5294-5303.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 5294-5303
-
-
Udwary, D.W.1
Casillas, L.K.2
Townsend, C.A.3
-
63
-
-
0028865744
-
Refined solution structure of 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the complementary strand of an oligodeoxynucleotide duplex as determined by 1H NMR
-
Johnston, D. S. & Stone, M. P. (1995). Refined solution structure of 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the complementary strand of an oligodeoxynucleotide duplex as determined by 1H NMR. Biochemistry, 34, 14037-14050.
-
(1995)
Biochemistry
, vol.34
, pp. 14037-14050
-
-
Johnston, D.S.1
Stone, M.P.2
-
64
-
-
0030155688
-
Demonstration of the catalytic roles and evidence for the physical association of type I fatty acid synthases and a polyketide synthase in the biosynthesis of aflatoxin B1
-
Watanabe, C. M. H., Wilson, D., Linz, J. E. & Townsend, C. A. (1996). Demonstration of the catalytic roles and evidence for the physical association of type I fatty acid synthases and a polyketide synthase in the biosynthesis of aflatoxin B1. Chem. Biol. 3, 463-469.
-
(1996)
Chem. Biol.
, vol.3
, pp. 463-469
-
-
Watanabe, C.M.H.1
Wilson, D.2
Linz, J.E.3
Townsend, C.A.4
-
65
-
-
0036752689
-
Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of aflatoxin B1
-
Watanabe, C. M. H., Townsend, C. A. (2002). Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of aflatoxin B1. Chem. Biol. 9, 981-988.
-
(2002)
Chem. Biol.
, vol.9
, pp. 981-988
-
-
Watanabe, C.M.H.1
Townsend, C.A.2
-
66
-
-
0029912229
-
Twenty-five co-regulated transcripts define a secondary metabolite gene cluster in Aspergillus nidulans
-
Brown, D. W., Yu, J.-H., Kelkar, H. S., Fernandes, M., Nesbitt, T. C., Keller, N. P. et al. (1996). Twenty-five co-regulated transcripts define a secondary metabolite gene cluster in Aspergillus nidulans. Proc. Natl. Acad. Sci. USA, 93, 1418-1422.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1418-1422
-
-
Brown, D.W.1
Yu, J.-H.2
Kelkar, H.S.3
Fernandes, M.4
Nesbitt, T.C.5
Keller, N.P.6
-
67
-
-
0032532795
-
Product identification of polyketide synthase coded by Aspergillus nidulans wA gene
-
Watanabe, A., Ono, Y., Fujii, I., Sankawa, U., Mayorga, M. E., Timberlake, W. E. & Ebizuka, Y. (1998). Product identification of polyketide synthase coded by Aspergillus nidulans wA gene. Tetrahedron Letters, 39, 7733-7736.
-
(1998)
Tetrahedron Letters
, vol.39
, pp. 7733-7736
-
-
Watanabe, A.1
Ono, Y.2
Fujii, I.3
Sankawa, U.4
Mayorga, M.E.5
Timberlake, W.E.6
Ebizuka, Y.7
-
68
-
-
0032890191
-
Re-identification of Aspergillus nidulans wA gene to code for a polyketide synthase of naphthopyrone
-
Watanabe, A., Fujii, I., Sankawa, U., Mayorga, M. E., Timberlake, W. E. & Ebizuka, Y. (1999). Re-identification of Aspergillus nidulans wA gene to code for a polyketide synthase of naphthopyrone. Tetrahedron Letters, 40, 91-94.
-
(1999)
Tetrahedron Letters
, vol.40
, pp. 91-94
-
-
Watanabe, A.1
Fujii, I.2
Sankawa, U.3
Mayorga, M.E.4
Timberlake, W.E.5
Ebizuka, Y.6
-
69
-
-
0031801247
-
The developmentally regulated alb1 gene of Aspergillus fumigatus: Its role in modulation of conidial morphology and virulence
-
Tsai, H. F., Chang, Y. C., Washburn, R. G., Wheeler, M. H. & Kwon-Chung, K. J. (1998). The developmentally regulated alb1 gene of Aspergillus fumigatus: Its role in modulation of conidial morphology and virulence. J. Bacteriol. 180, 3031-3038.
-
(1998)
J. Bacteriol.
, vol.180
, pp. 3031-3038
-
-
Tsai, H.F.1
Chang, Y.C.2
Washburn, R.G.3
Wheeler, M.H.4
Kwon-Chung, K.J.5
-
70
-
-
0031730240
-
Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence
-
Langfelder, K., Jahn, B., Gehringer, H., Schmidt, A., Wanner, G. & Brakhage, A. A. (1998). Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence. Med. Microbiol. Immunol. 187, 79-89.
-
(1998)
Med. Microbiol. Immunol.
, vol.187
, pp. 79-89
-
-
Langfelder, K.1
Jahn, B.2
Gehringer, H.3
Schmidt, A.4
Wanner, G.5
Brakhage, A.A.6
-
71
-
-
0035114569
-
Molecular cloning and characterization of WdPKS1, a gene involved in dihydroxynaphthalene melanin biosynthesis and virulence in Wangiella (Exophiala) dermatitidis
-
Feng, B., Wang, X., Hauser, M., Kaufmann, S., Jentsch, S., Haase, G. et al. (2001). Molecular cloning and characterization of WdPKS1, a gene involved in dihydroxynaphthalene melanin biosynthesis and virulence in Wangiella (Exophiala) dermatitidis. Infect. Immun. 69, 1781-1794.
-
(2001)
Infect. Immun.
, vol.69
, pp. 1781-1794
-
-
Feng, B.1
Wang, X.2
Hauser, M.3
Kaufmann, S.4
Jentsch, S.5
Haase, G.6
-
72
-
-
0033401325
-
A melanin polyketide synthase (PKS) gene from Nodulisporium sp. that shows homology to the pks1 gene of Colletotrichum lagenarium
-
Fulton, T. R., Ibrahim, N., Losada, M. C., Grzegorski, D. & Tkacz, J. S. (1999). A melanin polyketide synthase (PKS) gene from Nodulisporium sp. that shows homology to the pks1 gene of Colletotrichum lagenarium. Mol. Gen. Genet. 262, 714-720.
-
(1999)
Mol. Gen. Genet.
, vol.262
, pp. 714-720
-
-
Fulton, T.R.1
Ibrahim, N.2
Losada, M.C.3
Grzegorski, D.4
Tkacz, J.S.5
-
73
-
-
0037185614
-
A novel hexaketide naphthalene synthesized by a chimeric polyketide synthase composed of fungal pentaketide and heptaketide synthases
-
Watanabe, A. & Ebizuka, Y. (2002). A novel hexaketide naphthalene synthesized by a chimeric polyketide synthase composed of fungal pentaketide and heptaketide synthases. Tetrahedron Letters, 43, 843-846.
-
(2002)
Tetrahedron Letters
, vol.43
, pp. 843-846
-
-
Watanabe, A.1
Ebizuka, Y.2
-
74
-
-
0034711399
-
Dissecting the chain length specificity in bacterial aromatic polyketide synthases using chimeric genes
-
Burson, K. K. & Khosla, C. (2000). Dissecting the chain length specificity in bacterial aromatic polyketide synthases using chimeric genes. Tetrahedron, 56, 940-9408.
-
(2000)
Tetrahedron
, vol.56
, pp. 940-9408
-
-
Burson, K.K.1
Khosla, C.2
-
75
-
-
0035068075
-
Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans
-
Fujii, I., Watanabe, A., Sankawa, U. & Ebizuka, Y. (2001). Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans. Chem. Biol. 8, 189-197.
-
(2001)
Chem. Biol.
, vol.8
, pp. 189-197
-
-
Fujii, I.1
Watanabe, A.2
Sankawa, U.3
Ebizuka, Y.4
-
76
-
-
0034705130
-
Construction of hybrid peptide synthetases by module and domain fusions
-
Mootz, H. D., Schwarzer, D. & Marahiel, M. A. (2000). Construction of hybrid peptide synthetases by module and domain fusions. Proc. Natl. Acad. Sci. USA, 97, 5848-5853.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5848-5853
-
-
Mootz, H.D.1
Schwarzer, D.2
Marahiel, M.A.3
-
77
-
-
0035782925
-
Review: Protein secondary structure prediction continues to rise
-
Rost, B. (2001). Review: Protein secondary structure prediction continues to rise. J. Struct. Biol. 134, 204-218.
-
(2001)
J. Struct. Biol.
, vol.134
, pp. 204-218
-
-
Rost, B.1
-
78
-
-
0031576355
-
Do aligned sequences share the same fold?
-
Abagyan, R. A. & Batalov, S. (1997). Do aligned sequences share the same fold? J. Mol. Biol. 273, 355-368.
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 355-368
-
-
Abagyan, R.A.1
Batalov, S.2
-
79
-
-
0031854952
-
DIALIGN: Finding local similarities by multiple sequence alignment
-
Morgenstern, B., Frech, K., Dress, A. & Werner, T. (1998). DIALIGN: Finding local similarities by multiple sequence alignment. Bioinformatics, 14, 290-294.
-
(1998)
Bioinformatics
, vol.14
, pp. 290-294
-
-
Morgenstern, B.1
Frech, K.2
Dress, A.3
Werner, T.4
-
80
-
-
0032962457
-
Twilight zone of protein sequence alignments
-
Rost, B. (1999). Twilight zone of protein sequence alignments. Protein Eng. 12, 85-94.
-
(1999)
Protein Eng.
, vol.12
, pp. 85-94
-
-
Rost, B.1
-
81
-
-
0025183708
-
Basic local alignment search tool
-
Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman, D. J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
-
(1990)
J. Mol. Biol.
, vol.215
, pp. 403-410
-
-
Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
-
82
-
-
0036087630
-
CDD: A database of conserved domain alignments with links to domain three-dimensional structure
-
Marchler-Bauer, A., Panchenko, A. R., Shoemaker, B. A., Thiessen, P. A., Geer, L. Y. & Bryant, S. H. (2002). CDD: A database of conserved domain alignments with links to domain three-dimensional structure. Nucl. Acids Res. 30, 281-283.
-
(2002)
Nucl. Acids Res.
, vol.30
, pp. 281-283
-
-
Marchler-Bauer, A.1
Panchenko, A.R.2
Shoemaker, B.A.3
Thiessen, P.A.4
Geer, L.Y.5
Bryant, S.H.6
-
83
-
-
0029889988
-
Predicting one-dimensional protein structure by profile-based neural networks
-
Rost, B. (1996). Predicting one-dimensional protein structure by profile-based neural networks. Methods Enzymol. 266, 525-539.
-
(1996)
Methods Enzymol.
, vol.266
, pp. 525-539
-
-
Rost, B.1
-
84
-
-
0027169638
-
Improved prediction of protein secondary structure by use of sequence profiles and neural networks
-
Rost, B. & Sander, C. (1993). Improved prediction of protein secondary structure by use of sequence profiles and neural networks. Proc. Natl. Acad. Sci. USA, 90, 7558-7562.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7558-7562
-
-
Rost, B.1
Sander, C.2
-
85
-
-
0018735516
-
Statistical analysis of enzyme kinetic data
-
Cleland, W. W. (1975). Statistical analysis of enzyme kinetic data. Methods Enzymol. 63, 103-139.
-
(1975)
Methods Enzymol.
, vol.63
, pp. 103-139
-
-
Cleland, W.W.1
|