메뉴 건너뛰기




Volumn 3, Issue 6, 1996, Pages 463-469

Demonstration of the catalytic roles and evidence for the physical association of type I fatty acid synthases and a polyketide synthase in the biosynthesis of aflatoxin B1

Author keywords

Aflatoxin biosynthesis; Fatty acid synthase; Polyketide synthase; Protein association

Indexed keywords

ASPERGILLUS;

EID: 0030155688     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(96)90094-0     Document Type: Article
Times cited : (73)

References (36)
  • 1
    • 0025606149 scopus 로고
    • Molecular genetics of polyketides and its comparison to fatty acid biosynthesis
    • Hopwood, DA & Sherman, D.H. (1990). Molecular genetics of polyketides and its comparison to fatty acid biosynthesis. Annu. Rev. Genet. 24, 37-66.
    • (1990) Annu. Rev. Genet. , vol.24 , pp. 37-66
    • Hopwood, D.A.1    Sherman, D.H.2
  • 2
    • 0028811381 scopus 로고
    • Polyketide synthase gene manipulation: A structure-function approach in engineering novel antibiotics
    • Hutchinson, C.R. & Fujii, I. (1995). Polyketide synthase gene manipulation: a structure-function approach in engineering novel antibiotics. Annu. Rev. Microbiol. 49, 201-238.
    • (1995) Annu. Rev. Microbiol. , vol.49 , pp. 201-238
    • Hutchinson, C.R.1    Fujii, I.2
  • 3
    • 0027382486 scopus 로고
    • Polyketide synthesis: Prospects for hybrid antibiotics
    • Katz, L. & Donadio, S. (1993). Polyketide synthesis: prospects for hybrid antibiotics. Annu. Rev. Microbiol. 47, 875-912.
    • (1993) Annu. Rev. Microbiol. , vol.47 , pp. 875-912
    • Katz, L.1    Donadio, S.2
  • 4
    • 17944390314 scopus 로고
    • Biosynthesis von 6-methylsalicylsäure
    • Dimroth, P., Walter, H. & Lynen, F. (1970). Biosynthesis von 6-methylsalicylsäure. Eur. J. Biochem. 13, 98-110.
    • (1970) Eur. J. Biochem. , vol.13 , pp. 98-110
    • Dimroth, P.1    Walter, H.2    Lynen, F.3
  • 5
    • 0016739536 scopus 로고
    • Enzymic synthesis of an aromatic ring from acetate units
    • Kreuzaler, F. & Hahlbrock, K. (1975). Enzymic synthesis of an aromatic ring from acetate units. Eur. J. Biochem. 56, 205-213.
    • (1975) Eur. J. Biochem. , vol.56 , pp. 205-213
    • Kreuzaler, F.1    Hahlbrock, K.2
  • 6
    • 0029027352 scopus 로고
    • Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage
    • Cortes, J., Wiesmann, K.E.H., Roberts, G.A., Brown, M.J.B., Staunton, J. & Leadlay, P.F. (1995). Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage. Science 268, 1487-1489.
    • (1995) Science , vol.268 , pp. 1487-1489
    • Cortes, J.1    Wiesmann, K.E.H.2    Roberts, G.A.3    Brown, M.J.B.4    Staunton, J.5    Leadlay, P.F.6
  • 8
    • 0028784464 scopus 로고
    • Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases
    • Pieper, R., Luo, G., Cane, D.E. & Khosla, C. (1995). Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases. Nature 378, 263-266.
    • (1995) Nature , vol.378 , pp. 263-266
    • Pieper, R.1    Luo, G.2    Cane, D.E.3    Khosla, C.4
  • 9
    • 0030049982 scopus 로고    scopus 로고
    • Erythromycin biosynthesis: Kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates
    • Pieper, R., Ebert-Khosla, S., Cane, D. & Khosla, C. (1996). Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates. Biochemistry 35, 2054-2060.
    • (1996) Biochemistry , vol.35 , pp. 2054-2060
    • Pieper, R.1    Ebert-Khosla, S.2    Cane, D.3    Khosla, C.4
  • 13
    • 0027337609 scopus 로고
    • 1 induces the transversion of G→T in codon 249 of the p53 tumor gene in human hepatocytes
    • 1 induces the transversion of G→T in codon 249 of the p53 tumor gene in human hepatocytes. Proc. Natl. Acad. Sci. USA 90, 8586-8590.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8586-8590
    • Aguilar, F.1    Hussain, S.P.2    Cerutti, P.3
  • 14
    • 0025732215 scopus 로고
    • Mutational hotspot in the p53 gene in human hepatocellular carcinomas
    • Hsu, I.C., Metcalf, R.A., Sun, T., Wesh, J.A., Wang, N.J. & Harris, C.C. (1991). Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature 350, 427-428.
    • (1991) Nature , vol.350 , pp. 427-428
    • Hsu, I.C.1    Metcalf, R.A.2    Sun, T.3    Wesh, J.A.4    Wang, N.J.5    Harris, C.C.6
  • 16
    • 0003178418 scopus 로고
    • Evidence for the final steps in aflatoxin biosynthesis
    • Chatterjee, M. & Townsend, C.A. (1994). Evidence for the final steps in aflatoxin biosynthesis. J. Org. Chem. 59, 4424-4429.
    • (1994) J. Org. Chem. , vol.59 , pp. 4424-4429
    • Chatterjee, M.1    Townsend, C.A.2
  • 17
    • 0346033931 scopus 로고
    • Examination of tetrahydro- and dihydrobisfuran formation in aflatoxin biosynthesis: From whole cells to purified enzymes
    • (Petroski, R.J. & McCormick, S.P., eds), Plenum Press, New York
    • Townsend, C.A., McGuire, S.M., Brobst S.W., Graybill, T.L., Pal, K. & Barry, C.E. (1992). Examination of tetrahydro- and dihydrobisfuran formation in aflatoxin biosynthesis: from whole cells to purified enzymes. In Secondary-Metabolite Biosynthesis and Metabolism. (Petroski, R.J. & McCormick, S.P., eds), pp. 141-153, Plenum Press, New York.
    • (1992) Secondary-Metabolite Biosynthesis and Metabolism , pp. 141-153
    • Townsend, C.A.1    McGuire, S.M.2    Brobst, S.W.3    Graybill, T.L.4    Pal, K.5    Barry, C.E.6
  • 21
    • 0028115352 scopus 로고
    • The potential role of fatty acid initiation in the biosynthesis of the fungal aromatic polyketide aflatoxin B1
    • Brobst, S.W. & Townsend, C.A. (1994). The potential role of fatty acid initiation in the biosynthesis of the fungal aromatic polyketide aflatoxin B1. Can. J. Chem. 72, 200-207.
    • (1994) Can. J. Chem. , vol.72 , pp. 200-207
    • Brobst, S.W.1    Townsend, C.A.2
  • 22
    • 0021063709 scopus 로고
    • Stable isotope studies of anthraquinone intermediates in the aflatoxin pathway
    • Townsend, C.A. & Christensen, S.B. (1983). Stable isotope studies of anthraquinone intermediates in the aflatoxin pathway. Tetrahedron 21, 3575-3583.
    • (1983) Tetrahedron , vol.21 , pp. 3575-3583
    • Townsend, C.A.1    Christensen, S.B.2
  • 23
    • 0000543572 scopus 로고
    • Hexanoate as a starter unit in polyketide biosynthesis
    • Townsend, C.A., Christensen, S.B. & Trautwein, K. (1984). Hexanoate as a starter unit in polyketide biosynthesis. J. Am. Chem. Soc. 106, 3868-3869.
    • (1984) J. Am. Chem. Soc. , vol.106 , pp. 3868-3869
    • Townsend, C.A.1    Christensen, S.B.2    Trautwein, K.3
  • 24
    • 0023928338 scopus 로고
    • Stereochemical features of enoyl thiol ester reductase in averufin and fatty acid biosynthesis in Aspergillus parasiticus
    • Townsend, C.A., Brobst, S.W., Ramer, S.E. & Vederas, J.C. (1988). Stereochemical features of enoyl thiol ester reductase in averufin and fatty acid biosynthesis in Aspergillus parasiticus. J. Am. Chem. Soc. 110, 318-319.
    • (1988) J. Am. Chem. Soc. , vol.110 , pp. 318-319
    • Townsend, C.A.1    Brobst, S.W.2    Ramer, S.E.3    Vederas, J.C.4
  • 25
    • 0000595393 scopus 로고
    • Incorporation of labelled compounds into aflatoxin
    • Adye, J. & Mateles, R.I. (1964). Incorporation of labelled compounds into aflatoxin. Biochim. Biophys. Acta 86, 418-420.
    • (1964) Biochim. Biophys. Acta , vol.86 , pp. 418-420
    • Adye, J.1    Mateles, R.I.2
  • 27
    • 0028802415 scopus 로고
    • Characterization of the polyketide synthase gene (pksL1) required for aflatoxin biosynthesis in Aspergillus parasiticus
    • Feng, G.H. & Leonard, T.J. (1995). Characterization of the polyketide synthase gene (pksL1) required for aflatoxin biosynthesis in Aspergillus parasiticus. J. Bacteriol. 177, 6246-6254.
    • (1995) J. Bacteriol. , vol.177 , pp. 6246-6254
    • Feng, G.H.1    Leonard, T.J.2
  • 28
    • 0030040205 scopus 로고    scopus 로고
    • Structure and function of fas-1A, a gene encoding a putative fatty acid synthetase directly involved in aflatoxin biosynthesis in Aspergillus parasiticus
    • Mahanti, N., Bhatnagar, D., Cary, J.W., Joubran, J. & Linz, J.E. (1996). Structure and function of fas-1A, a gene encoding a putative fatty acid synthetase directly involved in aflatoxin biosynthesis in Aspergillus parasiticus. Appl. Eviron. Microbiol. 62, 191-195.
    • (1996) Appl. Eviron. Microbiol. , vol.62 , pp. 191-195
    • Mahanti, N.1    Bhatnagar, D.2    Cary, J.W.3    Joubran, J.4    Linz, J.E.5
  • 29
    • 0029006805 scopus 로고
    • Molecular biology of aflatoxin biosynthesis
    • Trail, F., Mahanti, N. & Linz, J.E. (1995). Molecular biology of aflatoxin biosynthesis. Microbiology 141, 755-765.
    • (1995) Microbiology , vol.141 , pp. 755-765
    • Trail, F.1    Mahanti, N.2    Linz, J.E.3
  • 30
    • 0029059472 scopus 로고
    • Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant
    • Revill, W.P., Bibb, M.J. & Hopwood, D.A. (1995). Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant. J. Bacteriol. 177, 3946-3952.
    • (1995) J. Bacteriol. , vol.177 , pp. 3946-3952
    • Revill, W.P.1    Bibb, M.J.2    Hopwood, D.A.3
  • 31
    • 0029125339 scopus 로고
    • Malonyl-coenzymeA:acyl carrier protein acyltransferase of Streptomyces glaucescens: A possible link between fatty acid and polyketide biosynthesis
    • Summers, R.G., Ali, A., Shen, B., Wessel, W.A. & Hutchinson, C.R. (1995). Malonyl-coenzymeA:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis. Biochemistry 35, 9389-9402.
    • (1995) Biochemistry , vol.35 , pp. 9389-9402
    • Summers, R.G.1    Ali, A.2    Shen, B.3    Wessel, W.A.4    Hutchinson, C.R.5
  • 32
    • 84985596900 scopus 로고
    • Biosynthetic incorporation of labeled tetraketide intermediates into dehydrocurvularin, a phytotoxin from Alternaria cinerariae, with assistance of β-oxidation inhibitors
    • Zhe, L, et al., & Vederas, J.C. (1992). Biosynthetic incorporation of labeled tetraketide intermediates into dehydrocurvularin, a phytotoxin from Alternaria cinerariae, with assistance of β-oxidation inhibitors. J. Am. Chem. Soc. 114, 1531-1533.
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 1531-1533
    • Zhe, L.1    Vederas, J.C.2
  • 33
    • 0015014228 scopus 로고
    • Norsolorinic acid from a mutant strain of Aspergillus parasiticus
    • Lee, L.S., Bennett, J.W., Goldblatt, L.A. & Lundin, R.E. (1971). Norsolorinic acid from a mutant strain of Aspergillus parasiticus. J. Am. Chem. Soc. 48, 93-94.
    • (1971) J. Am. Chem. Soc. , vol.48 , pp. 93-94
    • Lee, L.S.1    Bennett, J.W.2    Goldblatt, L.A.3    Lundin, R.E.4
  • 34
    • 0029039265 scopus 로고
    • Physical and transcriptional map of aflatoxin gene cluster in Aspergillus parasiticus and functional disruption of a gene involved early in the aflatoxin pathway
    • Trail, F., et al., & Linz J.E. (1995). Physical and transcriptional map of aflatoxin gene cluster in Aspergillus parasiticus and functional disruption of a gene involved early in the aflatoxin pathway. Appl. Environ. Microbiol. 61, 2665-2673.
    • (1995) Appl. Environ. Microbiol. , vol.61 , pp. 2665-2673
    • Trail, F.1    Linz, J.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.