Nimesulide and diclofenac inhibit lipopolysaccharide-induced hypothermia and tumour necrosis factor-α elevation in rats

Fundamental and Clinical Pharmacology

Volumn 16, Issue 4, 2002, Pages 303-309

  Dogan, Muberra Devrim ^a   Ataoglu, Haluk ^a   Akarsu, Eyup S ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Cyclooxygenase inhibitors; Fever; Proinflammatory cytokines; Systemic inflammation

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; NIMESULIDE; PROSTAGLANDIN SYNTHASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; FEVER; INDUCED HYPOTHERMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; RECTUM TEMPERATURE;

ANALYSIS OF VARIANCE; ANIMALS; BODY TEMPERATURE REGULATION; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DICLOFENAC; DOSE-RESPONSE RELATIONSHIP, DRUG; FEVER; HYPOTHERMIA; ISOENZYMES; LIPOPOLYSACCHARIDES; MALE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR; RECTUM; SULFONAMIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036399277     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1472-8206.2002.00093.x     Document Type: Article

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