Endotoxin shock: Thermoregulatory mechanisms

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 270, Issue 4 39-4, 1996, Pages

  Romanovsky, Andrej A ^a,b   Shido, Osamu ^a   Sakurada, Sohtaro ^a   Sugimoto, Naotoshi ^a   Nagasaka, Tetsuo ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b LEGACY RESEARCH   (United States)

Author keywords

behavioral thermoregulation; fever; hypothermia; rats; thermoeffector thresholds; thermogenesis; vasodilation; wide dead band control

Indexed keywords

ESCHERICHIA COLI ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE;

ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BODY TEMPERATURE; BRAIN OXYGEN CONSUMPTION; CONTROLLED STUDY; FEVER; HYPOTHALAMUS; HYPOTHERMIA; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTIC SHOCK; SKIN TEMPERATURE; THERMOGENESIS; THERMOREGULATION; VASODILATATION;

EID: 0029966703     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1996.270.4.r693     Document Type: Article

References (31)

1. Allen, F. M. Theory and therapy of shock: reduced temperatures in shock treatment. Am. J. Surg. 60: 335-348, 1943.
2. Blair, E., G. Henning, R. Hornick, and R. A. Cowley. Hypothermia in bacteremic shock. Arch. Surg. 89: 619-629, 1964.
3. Blalock, A., and M. F. Mason. A comparison of the effects of heat and those of cold in the prevention and treatment of shock. Arch. Surg. 42: 1054-1059, 1941.
4. Blatteis, C. M. Thermal response of hamsters to endotoxin. J. Therm. Biol. 8: 195-197, 1983.
5. Bone, R. C. Sepsis, the sepsis syndrome, multi-organ failure: a plea for comparable definitions. Ann. Intern. Med. 114: 332-333, 1991.
6. Centers for Disease Control. Increase in National Hospital Discharge Survey rates for septicemia-United States. 1979-1987. Morb. Mortal. Wkly. Rep. 39: 31-34, 1990.
7. Clemmer, T. P., C. J. Fisher, Jr., R. C. Bone, G. J. Slotman, C. A. Metz, F. O. Thomas, and The Methylprednisolone Severe Sepsis Study Group. Hypothermia in the sepsis syndrome and clinical outcome. Crit. Care Med. 20: 1395-1401, 1992.
8. DeRijk, R. H., M. Van Kampen, N. Van Rooijen, and F. Berkenbosch. Hypothermia to endotoxin involves reduced thermogenesis, macrophage-dependent mechanisms, and prostaglandins. Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R1-R8, 1994.
9. Gordon, C. J. Toxic-induced hypothermia and hypometabolism: do they increase uncertainty in the extrapolation of toxicological data from experimental animals to humans? Neurosci. Biobehav. Rev. 15: 95-98, 1991.
10. Gordon, C. J., K.-L. A. Lee, T.-L. A. Chen, P. Killough, and J. S. Ali. Dynamics of behavioral thermoregulation in the rat. Am. J. Physiol. 261 (Regulatory Integrative Comp. Physiol. 30): R705-R711, 1991.
11. Harris, R. L., D. M. Musher, K. Bloom, J. Gathe, L. Rice, B. Sugarman, T. W. Williams, Jr., and E. J. Young. Manifestations of sepsis. Arch. Intern. Med. 147: 1895-1906, 1987.
12. Hazinski, M. F., T. J. Iberti, N. R. MacIntyre, M. P. Parker, D. Tribett, S. Prion, and H. Chmel. Epidemiology, pathophysiology, and clinical presentation of gram-negative sepsis. Am. J. Crit. Care 2: 224-235, 1993.
13. Iriki, M., M. Hashimoto, and T. Saigusa. Threshold dissociation of thermoregulatory effector responses in febrile rabbits. Can. J. Physiol. Pharmacol. 65: 1304-1311, 1987.
14. Kluger, M. J. Fever: role of pyrogens and cryogens. Physiol. Rev. 71: 93-127, 1991.
15. MacKenzie, M. A., A. R. M. M. Hermus, H. C. H. Wollersheim, G. F. F. M. Pieters, A. G. H. Smals, R. A. Binkhorst, T. Thien, and P. W. C. Kloppenborg. Poikilothermia in man: pathophysiology and clinical implications. Medicine 70: 257-268, 1991.
16. Members of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit. Care Med. 20: 864-874, 1992.
17. Meyer, D. M., and J. W. Horton. Effect of moderate hypothermia in the treatment of canine hemorrhagic shock. Ann. Surg. 207: 462-469, 1988.
18. Parillo, J. E. (Moderator), M. M. Parker, C. Natanson, A. S. Suffredini, R. L. Danner, R. E. Cunnion, and F. P. Ognibene (Discussants). Septic shock in humans. Advances in understanding of pathogenesis, cardiovascular dysfunction, and therapy. Ann. Intern. Med. 113: 227-242, 1990.
19. Rips, R., J. Bellemin, and G. Boschi. Hypothermic effects of "pyrogens" in the mouse and interaction with lysine acetylsalicylate. In: Thermoregulation: Research and Clinical Applications, edited by P. Lomax and E Shonbaum. Basel. Karger, 1989, p. 153-155.
20. Romanovsky, A. A., and C. M. Blatteis. Body temperature elevation per se induces the late phase syndrome. In: Temperature Regulation: Recent Physiological and Pharmacological Advances, edited by A. S. Milton. Basel: Birkhauser, 1994, p. 41-46.
21. Romanovsky, A. A., and C. M. Blatteis. Thermoregulatory vasomotor responses of the guinea pig ear (Abstract). FASEB J. 8: A66, 1994.
22. Romanovsky, A. A., and C. M. Blatteis. Biphasic fever: what triggers the second temperature rise? Am. J. Physiol. 269 (Regulatory Integrative Cornp. Physiol. 38): R280-R286, 1995.
23. Romanovsky, A. A., E. K. Karman, and V. N. Gourine. Febrile response of the ferret to bacterial pyrogen: hypo- and hyperthermic phases. Zh. Evol. Biokhim. Fiziol. 28: 678-684, 1992.
24. Sakurada, S., O. Shido, K. Fujikake, and T. Nagasaka. Relationship between body core and peripheral temperatures at the onset of thermoregulatory responses in rats. Jpn. J. Physiol. 43: 659-667, 1993.
25. Shido, O., and T. Nagasaka. Metabolic and blood pressure response to feeding activity is enhanced in freely moving spontaneously hypertensive rats. Jpn. J. Physiol. 39: 537-548, 1989.
26. 25a.Shido, O., A. A. Romanovsky, S. Sakurada, N. Sugimoto, and T. Nagasaka. Behavioral and autonomic thermoregulation of rats injected with a large dose of LPS. In: Body Temperature and Metabolism, edited by T. Nagasaka and A. S. Milton. Tokyo: IPEC, 1995, p. 71-73.
27. Shido, O., N. Sugimoto, S. Sakurada, K. Fujikake, and T. Nagasaka. Behavioral and autonomic febrile responses to endotoxin in rats (Abstract). Pathophysiology 1, Suppl.: 182, 1994.
28. Stoner, H. B. The burned patient's response to the environment: the 1991 Everett Idris Evans Memorial Lecture. J. Burn Care Rehab. 12: 402-410, 1991.
29. Székely, M., and Z. Szelényi. The pathophysiology of fever in the neonate. In: Handbook of Experimental Pharmacology. Pyretics and Antipyretics, edited by A. S. Milton. Berlin: Springer, 1982, vol. 60, p. 479-528.
30. Tuchschmidt, J., D. Oblitas, and J. S. Fried. Oxygen consumption in sepsis and septic shock. Crit. Care Med. 19: 664-671, 1991.
31. Vybíral, S., M. Székely, L,. Janský, and L. Černý. Thermoregulation of the rabbit during the late phase of endotoxin fever. Pfluegers Arch. 410: 220-222, 1987.