메뉴 건너뛰기




Volumn 19, Issue 8, 2002, Pages 553-560

Gene therapy for renal disorders: What are the benefits for the elderly?

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOMEDULLIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSINOGEN; ARACHIDONATE 15 LIPOXYGENASE; ATRIAL NATRIURETIC FACTOR; BETA ADRENERGIC RECEPTOR; CYCLIN DEPENDENT KINASE 2; CYCLINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DECORIN; DIPEPTIDYL CARBOXYPEPTIDASE; FAS LIGAND; FIBROBLAST GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE 1; KALLIKREIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NITRIC OXIDE SYNTHASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; TRANSCRIPTION FACTOR E2F; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; VASCULOTROPIN;

EID: 0036388629     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-200219080-00001     Document Type: Review
Times cited : (16)

References (54)
  • 1
    • 0003402592 scopus 로고    scopus 로고
    • Bethesda (MD): National Institutes of Health, National Institutes of Diabetes and Digestive and Kidney Diseases
    • US renal data system. USRDS 2000 annual data report: atlas of end stage renal disease in the United States. Bethesda (MD): National Institutes of Health, National Institutes of Diabetes and Digestive and Kidney Diseases, 2000
    • (2000) USRDS 2000 Annual Data Report: Atlas of End Stage Renal Disease in the United States
  • 2
    • 0002431499 scopus 로고    scopus 로고
    • Gene therapy for renal diseases
    • Lien YH, Lai L. Gene therapy for renal diseases. Kidney Int 1997; 52 Suppl. 61: S 85-8
    • (1997) Kidney Int , vol.52 , Issue.SUPPL. 61
    • Lien, Y.H.1    Lai, L.2
  • 4
    • 0031910363 scopus 로고    scopus 로고
    • Strategies of gene transfer to the kidney
    • Imai E, Isaka Y. Strategies of gene transfer to the kidney. Kidney Int 1998; 53: 264-72
    • (1998) Kidney Int , vol.53 , pp. 264-272
    • Imai, E.1    Isaka, Y.2
  • 5
    • 0034864995 scopus 로고    scopus 로고
    • Gene therapy approach in renal disease in the 21st century
    • Imai E. Gene therapy approach in renal disease in the 21st century. Nephrol Dial Transplant 2001; 16 Suppl. 5: 26-34
    • (2001) Nephrol Dial Transplant , vol.16 , Issue.SUPPL. 5 , pp. 26-34
    • Imai, E.1
  • 6
    • 0034650348 scopus 로고    scopus 로고
    • Cardiovascular gene therapy
    • Ylä-Herttuala S, Martin JF. Cardiovascular gene therapy. Lancet 2000; 355: 213-22
    • (2000) Lancet , vol.355 , pp. 213-222
    • Ylä-Herttuala, S.1    Martin, J.F.2
  • 7
    • 0035810911 scopus 로고    scopus 로고
    • Therapeutic potential of nitric oxide synthase gene manipulation
    • von der Leyen HE, Dzau VJ. Therapeutic potential of nitric oxide synthase gene manipulation. Circulation 2001; 103: 2760-5
    • (2001) Circulation , vol.103 , pp. 2760-2765
    • Von der Leyen, H.E.1    Dzau, V.J.2
  • 8
    • 0035459161 scopus 로고    scopus 로고
    • Gene therapy for hypertension: The preclinical data
    • Phillips MI. Gene therapy for hypertension: the preclinical data. Hypertension 2001; 38: 543-8
    • (2001) Hypertension , vol.38 , pp. 543-548
    • Phillips, M.I.1
  • 10
    • 0003071676 scopus 로고    scopus 로고
    • Application of gene therapy to diabetic nephropathy
    • Isaka Y, Akagi Y, Ando Y, et al. Application of gene therapy to diabetic nephropathy. Kidney Int 1997; 52 Suppl. 60: S 100-3
    • (1997) Kidney Int , vol.52 , Issue.SUPPL. 60
    • Isaka, Y.1    Akagi, Y.2    Ando, Y.3
  • 11
    • 0035093075 scopus 로고    scopus 로고
    • Attenuation of hypertension and heart hypertrophy by adeno-associated virus delivering angiotensinogen antisense
    • Kimura B, Mohuczy D, Tang X, et al. Attenuation of hypertension and heart hypertrophy by adeno-associated virus delivering angiotensinogen antisense. Hypertension 2001; 37: 376-80
    • (2001) Hypertension , vol.37 , pp. 376-380
    • Kimura, B.1    Mohuczy, D.2    Tang, X.3
  • 12
    • 0010752221 scopus 로고    scopus 로고
    • Gene therapy for hypertension: Recombinant adeno-associated virus vector delivery of angiotensin type I receptor antisense in hypertensive double transgenic mice
    • Phillips MI, Kimura B, Zhang YC, et al. Gene therapy for hypertension: recombinant adeno-associated virus vector delivery of angiotensin type I receptor antisense in hypertensive double transgenic mice [abstract]. Hypertension 2000; 36: 204
    • (2000) Hypertension , vol.36 , pp. 204
    • Phillips, M.I.1    Kimura, B.2    Zhang, Y.C.3
  • 13
    • 0031944079 scopus 로고    scopus 로고
    • Kallikrein gene delivery attenuates hypertension and cardiac hypertrophy and enhances renal function in Goldblatt hypertensive rats
    • Yayama K, Wang C, Chao L, et al. Kallikrein gene delivery attenuates hypertension and cardiac hypertrophy and enhances renal function in Goldblatt hypertensive rats. Hypertension 1998; 31: 1104-10
    • (1998) Hypertension , vol.31 , pp. 1104-1110
    • Yayama, K.1    Wang, C.2    Chao, L.3
  • 14
    • 0033670493 scopus 로고    scopus 로고
    • Adrenomedullin gene delivery attenuates hypertension cardiac remodeling and renal injury in deoxycorticosterone acetate-salt hypertensive rats
    • Dobrzynski E, Wang C, Chao J, et al. Adrenomedullin gene delivery attenuates hypertension cardiac remodeling and renal injury in deoxycorticosterone acetate-salt hypertensive rats. Hypertension 2000; 36: 995-1001
    • (2000) Hypertension , vol.36 , pp. 995-1001
    • Dobrzynski, E.1    Wang, C.2    Chao, J.3
  • 15
    • 0031454520 scopus 로고    scopus 로고
    • Adrenomedullin gene delivery reduces blood pressure in spontaneously hypertensive rats
    • Chao J, Jin L, Lin KF, et al. Adrenomedullin gene delivery reduces blood pressure in spontaneously hypertensive rats. Hypertens Res 1997; 20: 269-77
    • (1997) Hypertens Res , vol.20 , pp. 269-277
    • Chao, J.1    Jin, L.2    Lin, K.F.3
  • 16
    • 0032126984 scopus 로고    scopus 로고
    • Atrial natriuretic peptide gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in salt-sensitive rats
    • Lin KF, Chao J, Chao L. Atrial natriuretic peptide gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in salt-sensitive rats. Hum Gene Ther 1998; 9: 1429-38
    • (1998) Hum Gene Ther , vol.9 , pp. 1429-1438
    • Lin, K.F.1    Chao, J.2    Chao, L.3
  • 17
    • 0030793748 scopus 로고    scopus 로고
    • Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery
    • Lin KF, Chao J, Chao L. Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery. Hypertension 1997; 30: 307-13
    • (1997) Hypertension , vol.30 , pp. 307-313
    • Lin, K.F.1    Chao, J.2    Chao, L.3
  • 18
    • 0033954747 scopus 로고    scopus 로고
    • New β-blocker: Prolonged reduction in high blood pressure with β 1 antisense oligodeoxy-nucleotides
    • Zhang YC, Kimura B, Shen L, et al. New β-blocker: prolonged reduction in high blood pressure with β 1 antisense oligodeoxy-nucleotides. Hypertension 2000; 35: 219-24
    • (2000) Hypertension , vol.35 , pp. 219-224
    • Zhang, Y.C.1    Kimura, B.2    Shen, L.3
  • 19
    • 0033966179 scopus 로고    scopus 로고
    • Angiotensin I converting enzyme antisense gene therapy causes permanent antihy-pertensive effects in the SHR
    • Wang H, Reaves PY, Gardon ML, et al. Angiotensin I converting enzyme antisense gene therapy causes permanent antihy-pertensive effects in the SHR. Hypertension 2000; 35: 202-8
    • (2000) Hypertension , vol.35 , pp. 202-208
    • Wang, H.1    Reaves, P.Y.2    Gardon, M.L.3
  • 20
    • 17944393912 scopus 로고    scopus 로고
    • Permanent cardiovascular protection from hypertension by the AT(1) receptor antisense gene therapy in hypertensive rat offspring
    • Reaves PY, Gelband CH, Wang H, et al. Permanent cardiovascular protection from hypertension by the AT(1) receptor antisense gene therapy in hypertensive rat offspring. Circ Res 1999; 85: e44-50
    • (1999) Circ Res , vol.85
    • Reaves, P.Y.1    Gelband, C.H.2    Wang, H.3
  • 21
    • 0032583951 scopus 로고    scopus 로고
    • Constitutive expression of VEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia
    • Baumgartner I, Pieczek A, Manor O, et al. Constitutive expression of VEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 1998; 97: 1114-23
    • (1998) Circulation , vol.97 , pp. 1114-1123
    • Baumgartner, I.1    Pieczek, A.2    Manor, O.3
  • 22
    • 0035004884 scopus 로고    scopus 로고
    • Improvement in chronic ischemic neuropathy after intramuscular phVEGF165 gene transfer in patients with critical limb ischemia
    • Simovic D, Isner JM, Ropper AH, et al. Improvement in chronic ischemic neuropathy after intramuscular phVEGF165 gene transfer in patients with critical limb ischemia. Arch Neurol 2001; 58: 761-8
    • (2001) Arch Neurol , vol.58 , pp. 761-768
    • Simovic, D.1    Isner, J.M.2    Ropper, A.H.3
  • 23
    • 0028798793 scopus 로고
    • Gene therapy inhibiting neointimal vascular lesion: In vivo transfer for endothelial-cell nitric oxide synthase gene
    • von der Leyen HE, Gibbons GH, Morishita R, et al. Gene therapy inhibiting neointimal vascular lesion: in vivo transfer for endothelial-cell nitric oxide synthase gene. Proc Natl Acad Sci U S A 1995; 92: 1137-41
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1137-1141
    • Von der Leyen, H.E.1    Gibbons, G.H.2    Morishita, R.3
  • 24
    • 0030850447 scopus 로고    scopus 로고
    • DNA transfer into vascular smooth muscle using fusogenic Sendai virus (HVJ)-liposomes
    • Mann MJ, Morishita R, Gibbons GH, et al. DNA transfer into vascular smooth muscle using fusogenic Sendai virus (HVJ)-liposomes. Mol Cell Biochem 1997; 172: 3-12
    • (1997) Mol Cell Biochem , vol.172 , pp. 3-12
    • Mann, M.J.1    Morishita, R.2    Gibbons, G.H.3
  • 25
    • 0000660514 scopus 로고    scopus 로고
    • Inhibition of in-stent plaque formation by inducible nitric oxide synthase-lipoplex-mediated gene therapy in a pig femoral artery stent model
    • von der Leyen HE, Muhs A, Shrader J, et al. Inhibition of in-stent plaque formation by inducible nitric oxide synthase-lipoplex-mediated gene therapy in a pig femoral artery stent model. J Am Coll Cardiol 2000; 35 Suppl A: 280A
    • (2000) J Am Coll Cardiol , vol.35 , Issue.SUPPL. A
    • Von der Leyen, H.E.1    Muhs, A.2    Shrader, J.3
  • 26
    • 0033619428 scopus 로고    scopus 로고
    • Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The prevent single-centre, randomized, controlled trial
    • Mann MJ, Whittemore AD, Donaldson MC, et al. Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the Prevent single-centre, randomized, controlled trial. Lancet 1999; 354: 1493-8
    • (1999) Lancet , vol.354 , pp. 1493-1498
    • Mann, M.J.1    Whittemore, A.D.2    Donaldson, M.C.3
  • 27
    • 0030893643 scopus 로고    scopus 로고
    • Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts
    • Mann MJ, Gibbons GH, Tsao PS, et al. Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts. J Clin Invest 1997; 99: 1295-301
    • (1997) J Clin Invest , vol.99 , pp. 1295-1301
    • Mann, M.J.1    Gibbons, G.H.2    Tsao, P.S.3
  • 28
    • 10144227768 scopus 로고    scopus 로고
    • Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis
    • Akagi Y, Isaka Y, Arai M, et al. Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int 1996; 50: 148-55
    • (1996) Kidney Int , vol.50 , pp. 148-155
    • Akagi, Y.1    Isaka, Y.2    Arai, M.3
  • 29
    • 0032103310 scopus 로고    scopus 로고
    • Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo
    • Maeshima Y, Kashihara N, Yasuda T, et al. Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo. J Clin Invest 1998; 101: 2589-97
    • (1998) J Clin Invest , vol.101 , pp. 2589-2597
    • Maeshima, Y.1    Kashihara, N.2    Yasuda, T.3
  • 30
    • 0034050031 scopus 로고    scopus 로고
    • In vivo administration of a nuclear transcription factor-κB decoy suppresses experimental crescentic glomerulonephritis
    • Tomita N, Morishita R, Lan H, et al. In vivo administration of a nuclear transcription factor-κB decoy suppresses experimental crescentic glomerulonephritis. J Am Soc Nephrol 2000; 11: 1244-52
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1244-1252
    • Tomita, N.1    Morishita, R.2    Lan, H.3
  • 31
    • 0033539695 scopus 로고    scopus 로고
    • Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis
    • Munger KA, Montero A, Fukunaga M, et al. Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis. Proc Natl Acad Sci U S A 1999; 96: 13375-80
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13375-13380
    • Munger, K.A.1    Montero, A.2    Fukunaga, M.3
  • 32
    • 0029905441 scopus 로고    scopus 로고
    • Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney
    • Isaka Y, Brees DK, Ikegaya K, et al. Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nat Med 1996; 2: 418-23
    • (1996) Nat Med , vol.2 , pp. 418-423
    • Isaka, Y.1    Brees, D.K.2    Ikegaya, K.3
  • 33
    • 0032910706 scopus 로고    scopus 로고
    • Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extra-cellular matrix accumulation in experimental glomerulonephritis
    • Isaka Y, Akagi Y, Ando Y, et al. Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extra-cellular matrix accumulation in experimental glomerulonephritis. Kidney Int 1999; 55: 465-75
    • (1999) Kidney Int , vol.55 , pp. 465-475
    • Isaka, Y.1    Akagi, Y.2    Ando, Y.3
  • 34
    • 0035019610 scopus 로고    scopus 로고
    • Electroporation-mediated PDGF receptor-IgG chimera gene transfer ameliorates experimental glomerulonephritis
    • Nakamura H, Isaka Y, Tsujie M, et al. Electroporation-mediated PDGF receptor-IgG chimera gene transfer amelio-rates experimental glomerulonephritis. Kidney Int 2001; 59: 2134-45
    • (2001) Kidney Int , vol.59 , pp. 2134-2145
    • Nakamura, H.1    Isaka, Y.2    Tsujie, M.3
  • 35
    • 0029929229 scopus 로고    scopus 로고
    • In vivo targeting of inducible NO synthase with oligodeoxynucleotides protects rat kidney against ischemia
    • Noiri E, Peresleni T, Miller F, et al. In vivo targeting of inducible NO synthase with oligodeoxynucleotides protects rat kidney against ischemia. J Clin Invest 1996; 97: 2377-83
    • (1996) J Clin Invest , vol.97 , pp. 2377-2383
    • Noiri, E.1    Peresleni, T.2    Miller, F.3
  • 36
    • 0029788947 scopus 로고    scopus 로고
    • Antisense oligonucleotides for ICAM-1 attenuate reperfusion injury and renal failure in the rat
    • Haller H, Dragun D, Miethke A, et al. Antisense oligonucleotides for ICAM-1 attenuate reperfusion injury and renal failure in the rat. Kidney Int 1996; 50: 473-80
    • (1996) Kidney Int , vol.50 , pp. 473-480
    • Haller, H.1    Dragun, D.2    Miethke, A.3
  • 37
    • 0031817101 scopus 로고    scopus 로고
    • Human kallikrein gene delivery protects against gentamycin-induced nephrotoxicity in rats
    • Murakami H, Yayama K, Chao L, et al. Human kallikrein gene delivery protects against gentamycin-induced nephrotoxicity in rats. Kidney Int 1998; 53: 1305-13
    • (1998) Kidney Int , vol.53 , pp. 1305-1313
    • Murakami, H.1    Yayama, K.2    Chao, L.3
  • 38
    • 0033012868 scopus 로고    scopus 로고
    • Atrial natriuretic peptide gene delivery attenuates gentamycin-induced nephrotoxicity in rats
    • Murakami H, Yayama K, Chao J, et al. Atrial natriuretic peptide gene delivery attenuates gentamycin-induced nephrotoxicity in rats. Nephrol Dial Transplant 1999; 14: 1376-84
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 1376-1384
    • Murakami, H.1    Yayama, K.2    Chao, J.3
  • 39
    • 0032572988 scopus 로고    scopus 로고
    • Protection against allograft rejection with intercellular adhesion molecule-1 antisense oligodeoxynucleotides
    • Stepkowski SM, Wang ME, Condon TP, et al. Protection against allograft rejection with intercellular adhesion molecule-1 antisense oligodeoxynucleotides. Transplantation 1998; 66: 699-707
    • (1998) Transplantation , vol.66 , pp. 699-707
    • Stepkowski, S.M.1    Wang, M.E.2    Condon, T.P.3
  • 40
    • 0345628010 scopus 로고    scopus 로고
    • Fas ligand gene transfer to renal allografts in rats: Effect on allograft survival
    • Swenson KM, Ke B, Wang T, et al. Fas ligand gene transfer to renal allografts in rats: effect on allograft survival. Transplantation 1998; 65: 155-60
    • (1998) Transplantation , vol.65 , pp. 155-160
    • Swenson, K.M.1    Ke, B.2    Wang, T.3
  • 41
    • 0034026805 scopus 로고    scopus 로고
    • CTLA4Ig gene transfer prolongs survival and induces donor-specific tolerance in a rat renal allograft
    • Tomasoni S, Azzollini N, Casiraghi F, et al. CTLA4Ig gene transfer prolongs survival and induces donor-specific tolerance in a rat renal allograft. J Am Soc Nephrol 2000; 11: 747-52
    • (2000) J Am Soc Nephrol , vol.11 , pp. 747-752
    • Tomasoni, S.1    Azzollini, N.2    Casiraghi, F.3
  • 42
    • 0035160706 scopus 로고    scopus 로고
    • Tolerance to solid organ transplants through transfer of MHC class II genes
    • Sonntag KC, Emery DW, Yasumoto A, et al. Tolerance to solid organ transplants through transfer of MHC class II genes. J Clin Invest 2001; 107: 65-71
    • (2001) J Clin Invest , vol.107 , pp. 65-71
    • Sonntag, K.C.1    Emery, D.W.2    Yasumoto, A.3
  • 43
    • 0034116631 scopus 로고    scopus 로고
    • Evaluation of the effects of intramyocardial injection of DNA expressing vascular endothelial growth factor (VEGF) in a myocardial infarction model in the rat: Angiogenesis and angioma formation
    • Schwarz ER, Speakman MT, Patterson M, et al. Evaluation of the effects of intramyocardial injection of DNA expressing vascular endothelial growth factor (VEGF) in a myocardial infarction model in the rat: angiogenesis and angioma formation. J Am Coll Cardiol 2000; 35: 1323-30
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1323-1330
    • Schwarz, E.R.1    Speakman, M.T.2    Patterson, M.3
  • 44
    • 0029031549 scopus 로고
    • A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo
    • Morishita R, Gibbons GH, Horiuchi M, et al. A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Proc Natl Acad Sci U S A 1995; 92: 5855-9
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5855-5859
    • Morishita, R.1    Gibbons, G.H.2    Horiuchi, M.3
  • 46
    • 0034640230 scopus 로고    scopus 로고
    • Gene therapy on trial
    • Balter M. Gene therapy on trial. Science 2000; 288: 951-7
    • (2000) Science , vol.288 , pp. 951-957
    • Balter, M.1
  • 47
    • 0034830365 scopus 로고    scopus 로고
    • Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors
    • Donste A, Volger CA, Muzyczka N, et al. Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors. Gene Ther 2001; 8: 1343-6
    • (2001) Gene Ther , vol.8 , pp. 1343-1346
    • Donste, A.1    Volger, C.A.2    Muzyczka, N.3
  • 48
    • 0030859292 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract
    • Schwartz DA, Quinn TJ, Thorne PS, et al. CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract. J Clin Invest 1997; 100: 68-73
    • (1997) J Clin Invest , vol.100 , pp. 68-73
    • Schwartz, D.A.1    Quinn, T.J.2    Thorne, P.S.3
  • 49
    • 0026878142 scopus 로고
    • Gene transfer in vivo with DNA-liposome complexes: Safety and acute toxicity in mice
    • Stewart MJ, Plautz GE, Buono LD, et al. Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice. Hum Gene Ther 1992; 3: 267-75
    • (1992) Hum Gene Ther , vol.3 , pp. 267-275
    • Stewart, M.J.1    Plautz, G.E.2    Buono, L.D.3
  • 50
    • 0028238877 scopus 로고
    • No lung toxicity after repeated aerosol or intravenous delivery of plasmid-cationic liposome complexes
    • Canonico AE, Plitman JD, Conary JT, et al. No lung toxicity after repeated aerosol or intravenous delivery of plasmid-cationic liposome complexes. J Appl Physiol 1994; 77: 415-9
    • (1994) J Appl Physiol , vol.77 , pp. 415-419
    • Canonico, A.E.1    Plitman, J.D.2    Conary, J.T.3
  • 51
    • 0030806664 scopus 로고    scopus 로고
    • Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice
    • Henry SP, Taylor J, Midgley L, et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice. Antisense Nucleic Acid Drug Dev 1997; 7: 473-81
    • (1997) Antisense Nucleic Acid Drug Dev , vol.7 , pp. 473-481
    • Henry, S.P.1    Taylor, J.2    Midgley, L.3
  • 52
    • 0033060190 scopus 로고    scopus 로고
    • Evaluation of the renal effects of an antisense phosphorothioate oligodeoxynucleotide in monkeys
    • Monteith DK, Horner MJ, Gillett NA, et al. Evaluation of the renal effects of an antisense phosphorothioate oligodeoxynucleotide in monkeys. Toxicol Pathol 1999; 27: 307-17
    • (1999) Toxicol Pathol , vol.27 , pp. 307-317
    • Monteith, D.K.1    Horner, M.J.2    Gillett, N.A.3
  • 53
    • 0033378009 scopus 로고    scopus 로고
    • C-raf-1 depletion and tumor responses in patients treated with c-raf-1 antisense oligodeoxynucleotide ISIS 5132 (CGP 69846A)
    • O'Dwyer PJ, Stevenson JP, Gallagher M, et al. c-raf-1 depletion and tumor responses in patients treated with c-raf-1 antisense oligodeoxynucleotide ISIS 5132 (CGP 69846A). Clin Cancer Res 1999; 5: 3977-82
    • (1999) Clin Cancer Res , vol.5 , pp. 3977-3982
    • O'Dwyer, P.J.1    Stevenson, J.P.2    Gallagher, M.3
  • 54
    • 0032954323 scopus 로고    scopus 로고
    • Hemodynamic changes induced by liposomes and liposome-encapsulated hemoglobin in pigs: A model for pseudoallergic cardiopulmonary reactions to liposomes. Role of complement and inhibition by soluble CR1 and anti-C5a antibody
    • Szebeni J, Fontana JL, Wassef NM, et al. Hemodynamic changes induced by liposomes and liposome-encapsulated hemoglobin in pigs: a model for pseudoallergic cardiopulmonary reactions to liposomes. Role of complement and inhibition by soluble CR1 and anti-C5a antibody. Circulation 1999; 99: 2302-9
    • (1999) Circulation , vol.99 , pp. 2302-2309
    • Szebeni, J.1    Fontana, J.L.2    Wassef, N.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.