Atrial natriuretic peptide gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in salt-sensitive rats

Human Gene Therapy

Volumn 9, Issue 10, 1998, Pages 1429-1438

  Lin, Kuei Fu ^a   Chao, Julie ^a   Chao, Lee ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CYCLIC GMP; SODIUM CHLORIDE;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; EXPRESSION VECTOR; GENE TARGETING; GLOMERULUS FILTRATION RATE; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; HYPERTENSION; IMMUNOREACTIVITY; KIDNEY BLOOD FLOW; KIDNEY INJURY; MALE; NONHUMAN; RAT; SODIUM EXCRETION; URINE LEVEL;

EID: 0032126984     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.10-1429     Document Type: Article

References (9)

1. AKABANE, S., IMANISHI, M., MATSUSHIMA, Y., KAWAMURA, M., KURAMOCHI, M., ITO, K., and OMAE, T. (1988). Renal actions of atrial natriuretic peptide on the postischemic kidney. Can. J. Physiol. Pharmacol. 66, 601-607.
2. ATLAS, S., and MAACK, T. (1992). Atrial natriuretic factor. In: Handbook of Physiology: Renal Physiology. E.E. Windhager, ed. (Oxford University Press, New York) pp. 1577-1673.
3. BOUHNIK, J., RICHOUX, J.P., HUANG, H., SAVOIE, F., BAUSSANT, T., ALHENC-GELAS, F., and CORVOL, P. (1992). Hypertension in Dahl salt-sensitive rats: Biochemical and immunohistochemical studies. Clin. Sci. 83, 13-22.
4. BRENNER, B.M., BALLERMANN, B.J., GUNNING, M.E., and ZEIDEL, M.L. (1990). Diverse biological actions of atrial natriuretic peptide. Physiol. Rev. 70, 665-699.
5. CANTIN, M., and GENEST, J. (1985). The heart and the atrial natriuretic factor. Endocr. Rev. 6, 107-127.
6. CHEN, L.M., CHAO, L., and CHAO, J. (1997). Adenovirus-mediated delivery of human kallikrein-binding gene reduces blood pressure of spontaneously hypertensive rats. Hum. Gene Ther. 8, 341-347.
7. CUSSON, J.R., THIBAULT, G., CANTIN, M., and LAROCHELLE, P. (1990). Prolonged low dose infusion of atrial natriuretic factor in essential hypertension. Exp. Hypertens. 12, 111-135.
8. DE BOLD, A.J. (1985). Atrial natriuretic factor: A hormone produced by the heart. Science 230, 767-770.
9. DE BOLD, A.J., BORENSTEIN, H.B., VERESS, A.T., and SONNENBERG, H. (1981). A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats. Life Sci. 28, 89-94.