-
1
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
M. Serrano, H. Lee, L. Chin, C. Cordon-Cardo, D. Beach, R.A. DePinho, Role of the INK4a locus in tumor suppression and cell mortality, Cell 85 (1996) 27-37.
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
DePinho, R.A.6
-
2
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
T. Kamijo, F. Zindy, M.F. Roussel, D.E. Quelle, J.R. Downing, R.A. Ashmun, G. Grosveld, C.J. Sherr, Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF, Cell 91 (1997) 649-659.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
3
-
-
0034660892
-
The Pezcoller lecture: Cancer cell cycles revisited
-
C.J. Sherr, The Pezcoller lecture: cancer cell cycles revisited, Cancer Res. 60 (2000) 3689-3695.
-
(2000)
Cancer Res.
, vol.60
, pp. 3689-3695
-
-
Sherr, C.J.1
-
4
-
-
0035487104
-
The INK4a/ARF network in tumour suppression
-
C.J. Sherr, The INK4a/ARF network in tumour suppression, Nat. Rev. Mol. Cell. Biol. 2 (2001) 731-737.
-
(2001)
Nat. Rev. Mol. Cell. Biol.
, vol.2
, pp. 731-737
-
-
Sherr, C.J.1
-
5
-
-
0032504783
-
ARF links the tumor suppressors pRB and p53
-
S. Bates, A.C. Phillips, P.A. Clarke, F. Stott, G. Peters, R.L. Ludwig, K.H. Vousden, p14ARF links the tumor suppressors pRB and p53, Nature 395 (1998) 124-125.
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
Phillips, A.C.2
Clarke, P.A.3
Stott, F.4
Peters, G.5
Ludwig, R.L.6
Vousden, K.H.7
-
6
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Y. Zhang, Y. Xiong, W.G. Yarbrough, ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways, Cell 92(1998) 725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
7
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
J. Pomerantz, N. Schreiber-Agus, N.J. Liegeois, A. Silverman, L. Alland, L. Chin, J. Potes, K. Chen, I. Orlow, H.W. Lee, C. Cordon-Cardo, R.A. DePinho, The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53, Cell 92 (1998) 713-723.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
8
-
-
0034064361
-
The INK4a/ARF locus in murine tumorigenesis
-
M. Serrano, The INK4a/ARF locus in murine tumorigenesis, Carcinogenesis 21 (2000) 865-869.
-
(2000)
Carcinogenesis
, vol.21
, pp. 865-869
-
-
Serrano, M.1
-
9
-
-
0033403839
-
Induction of the human ARF protein by serum starvation
-
R. Inoue, C. Asker, U. Klangby, P. Pisa, K.G. Wiman, Induction of the human ARF protein by serum starvation, Anticancer Res.
-
(1999)
Anticancer Res.
, vol.19
, pp. 2939-2943
-
-
Inoue, R.1
Asker, C.2
Klangby, U.3
Pisa, P.4
Wiman, K.G.5
-
10
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
D.E. Quelle, F. Zindy, R.A. Ashmun, C.J. Sherr, Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest, Cell 83 (1995) 993-1000.
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
11
-
-
85047700405
-
Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways
-
H.O. Weber, T. Samuel, P. Rauch, J.O. Funk, Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways, Oncogene 21 (2002) 3207-3212.
-
(2002)
Oncogene
, vol.21
, pp. 3207-3212
-
-
Weber, H.O.1
Samuel, T.2
Rauch, P.3
Funk, J.O.4
-
12
-
-
0032573088
-
p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation
-
A. Radfar, I. Unnikrishnan, H.W. Lee, R.A. DePinho, N. Rosenberg, p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation, Proc. Natl. Acad. Sci. USA 95 (1998) 13194-13199.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13194-13199
-
-
Radfar, A.1
Unnikrishnan, I.2
Lee, H.W.3
DePinho, R.A.4
Rosenberg, N.5
-
13
-
-
0034685531
-
Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells
-
C.T. Yang, L. You, C.C. Yeh, J.W. Chang, F. Zhang, F. McCormick, D.M. Jablons, Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells, J. Natl. Cancer Inst. 92 (2000) 636-641.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 636-641
-
-
Yang, C.T.1
You, L.2
Yeh, C.C.3
Chang, J.W.4
Zhang, F.5
McCormick, F.6
Jablons, D.M.7
-
14
-
-
85047698445
-
Adenovirus-mediated overex-pression of p14(ARF) induces p53 and Bax-independent apopto-sis
-
P.G. Hemmati, B. Gillissen, C. Von Haefen, J. Wendt, L. Starck, D. Guner, B. Dorken, P.T. Daniel, Adenovirus-mediated overex-pression of p14(ARF) induces p53 and Bax-independent apopto-sis, Oncogene 21 (2002) 3149-3161.
-
(2002)
Oncogene
, vol.21
, pp. 3149-3161
-
-
Hemmati, P.G.1
Gillissen, B.2
Von Haefen, C.3
Wendt, J.4
Starck, L.5
Guner, D.6
Dorken, B.7
Daniel, P.T.8
-
15
-
-
0036311122
-
p53-Independent apoptosis is induced by the p19(ARF) tumor suppressor
-
K. Tsuji, K. Mizumoto, H. Sudo, K. Kouyama, E. Ogata, M. Matsuoka, p53-Independent apoptosis is induced by the p19(ARF) tumor suppressor, Biochem. Biophys. Res. Commun. 295 (2002) 621-629.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.295
, pp. 621-629
-
-
Tsuji, K.1
Mizumoto, K.2
Sudo, H.3
Kouyama, K.4
Ogata, E.5
Matsuoka, M.6
-
16
-
-
0033569423
-
INK4a/ARF mutations accelerate lympho-magenesis and promote chemoresistance by disabling p53
-
C.A. Schmitt, M.E. McCurrach, E. de Stanchina, R.R. Wallace-Brodeur, S.W. Lowe, INK4a/ARF mutations accelerate lympho-magenesis and promote chemoresistance by disabling p53, Genes Dev. 13 (1999) 2670-2677.
-
(1999)
Genes Dev.
, vol.13
, pp. 2670-2677
-
-
Schmitt, C.A.1
McCurrach, M.E.2
De Stanchina, E.3
Wallace-Brodeur, R.R.4
Lowe, S.W.5
-
18
-
-
0031439355
-
Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27
-
Y. Katayose, M. Kim, A.N. Rakkar, Z. Li, K.H. Cowan, P. Seth, Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27, Cancer Res. 57 (1997) 5441-5445.
-
(1997)
Cancer Res.
, vol.57
, pp. 5441-5445
-
-
Katayose, Y.1
Kim, M.2
Rakkar, A.N.3
Li, Z.4
Cowan, K.H.5
Seth, P.6
-
19
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
F.J. Stott, S. Bates, M.C. James, B.B. McConnell, M. Starborg, S. Brookes, I. Palmero, K. Ryan, E. Hara, K.H. Vousden, G. Peters, The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2, EMBO J. 17 (1998) 5001-5014.
-
(1998)
EMBO J.
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
20
-
-
0029028881
-
Cytotoxic effects of adenovirus-mediated wt p53 protein expression in normal and tumor mammary epithelial cells
-
D. Katayose, J. Gudas, H. Nguyen, S. Srivastava, K.H. Cowan, P. Seth, Cytotoxic effects of adenovirus-mediated wt p53 protein expression in normal and tumor mammary epithelial cells, Clin. Cancer Res. 1 (1995) 889-897.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 889-897
-
-
Katayose, D.1
Gudas, J.2
Nguyen, H.3
Srivastava, S.4
Cowan, K.H.5
Seth, P.6
-
21
-
-
14444284332
-
Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells
-
C. Craig, M. Kim, E. Ohri, R. Wersto, D. Katayose, Z. Li, Y.H. Choi, B. Mudahar, S. Srivastava, P. Seth, K. Cowan, Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells, Oncogene 16 (1998) 265-272.
-
(1998)
Oncogene
, vol.16
, pp. 265-272
-
-
Craig, C.1
Kim, M.2
Ohri, E.3
Wersto, R.4
Katayose, D.5
Li, Z.6
Choi, Y.H.7
Mudahar, B.8
Srivastava, S.9
Seth, P.10
Cowan, K.11
-
22
-
-
0028821895
-
Effects of a recombinant adenovirus expressing WAF1/Cip1 on cell growth, cell cycle, and apoptosis
-
D. Katayose, R. Wersto, K.H. Cowan, P. Seth, Effects of a recombinant adenovirus expressing WAF1/Cip1 on cell growth, cell cycle, and apoptosis, Cell. Growth Differ. 6 (1995) 1207-1212.
-
(1995)
Cell. Growth Differ.
, vol.6
, pp. 1207-1212
-
-
Katayose, D.1
Wersto, R.2
Cowan, K.H.3
Seth, P.4
-
23
-
-
8244262438
-
A recombinant adenovirus expressing p27Kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells
-
C. Craig, R. Wersto, M. Kim, E. Ohri, Z. Li, D. Katayose, S.J. Lee, J. Trepel, K. Cowan, P. Seth, A recombinant adenovirus expressing p27Kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells, Oncogene 14 (1997) 2283-2289.
-
(1997)
Oncogene
, vol.14
, pp. 2283-2289
-
-
Craig, C.1
Wersto, R.2
Kim, M.3
Ohri, E.4
Li, Z.5
Katayose, D.6
Lee, S.J.7
Trepel, J.8
Cowan, K.9
Seth, P.10
-
24
-
-
0035843123
-
Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53
-
S.S. Bacus, A.V. Gudkov, M. Lowe, L. Lyass, Y. Yung, A.P. Komarov, K. Keyomarsi, Y. Yarden, R. Seger, Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53, Oncogene 20 (2001) 147-155.
-
(2001)
Oncogene
, vol.20
, pp. 147-155
-
-
Bacus, S.S.1
Gudkov, A.V.2
Lowe, M.3
Lyass, L.4
Yung, Y.5
Komarov, A.P.6
Keyomarsi, K.7
Yarden, Y.8
Seger, R.9
-
25
-
-
0032191393
-
Tumor surveillance via the ARF-p53 pathway
-
C.J. Sherr, Tumor surveillance via the ARF-p53 pathway, Genes Dev. 12 (1998) 2984-2991.
-
(1998)
Genes Dev.
, vol.12
, pp. 2984-2991
-
-
Sherr, C.J.1
-
26
-
-
0029094704
-
Cell cycle arrest and inhibition of tumor cell proliferation by the p16INK4 gene mediated by an adenovirus vector
-
X. Jin, D. Nguyen, W.W. Zhang, A.P. Kyritsis, J.A. Roth, Cell cycle arrest and inhibition of tumor cell proliferation by the p16INK4 gene mediated by an adenovirus vector, Cancer Res. 55 (1995) 3250-3253.
-
(1995)
Cancer Res.
, vol.55
, pp. 3250-3253
-
-
Jin, X.1
Nguyen, D.2
Zhang, W.W.3
Kyritsis, A.P.4
Roth, J.A.5
-
27
-
-
0030614944
-
Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death
-
V. Sandig, K. Brand, S. Herwig, J. Lukas, J. Bartek, M. Strauss, Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death, Nat. Med. 3 (1997) 313-319.
-
(1997)
Nat. Med.
, vol.3
, pp. 313-319
-
-
Sandig, V.1
Brand, K.2
Herwig, S.3
Lukas, J.4
Bartek, J.5
Strauss, M.6
-
28
-
-
0032543305
-
Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression
-
S.P. Frizelle, J. Grim, J. Zhou, P. Gupta, D.T. Curiel, J. Geradts, R.A. Kratzke, Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression, Oncogene 16 (1998) 3087-3095.
-
(1998)
Oncogene
, vol.16
, pp. 3087-3095
-
-
Frizelle, S.P.1
Grim, J.2
Zhou, J.3
Gupta, P.4
Curiel, D.T.5
Geradts, J.6
Kratzke, R.A.7
-
29
-
-
0040298568
-
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
-
R.U. Janicke, M.L. Sprengart, M.R. Wati, A.G. Porter, Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis, J. Biol. Chem. 273 (1998) 9357-9360.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9357-9360
-
-
Janicke, R.U.1
Sprengart, M.L.2
Wati, M.R.3
Porter, A.G.4
-
30
-
-
0037181478
-
Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6
-
M.M. Mc Gee, E. Hyland, G. Campiani, A. Ramunno, V. Nacci, D.M. Zisterer, Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6, FEBS Lett. 515 (2002) 66-70.
-
(2002)
FEBS Lett.
, vol.515
, pp. 66-70
-
-
Mc Gee, M.M.1
Hyland, E.2
Campiani, G.3
Ramunno, A.4
Nacci, V.5
Zisterer, D.M.6
-
31
-
-
0036494469
-
Expression of p14ARF overcomes tumor resistance to p53
-
W. Lu, J. Lin, J. Chen, Expression of p14ARF overcomes tumor resistance to p53, Cancer Res. 62 (2002) 1305-1310.
-
(2002)
Cancer Res.
, vol.62
, pp. 1305-1310
-
-
Lu, W.1
Lin, J.2
Chen, J.3
-
32
-
-
0035756435
-
Recombinant adenovirus vectors for gene therapy and clinical trials
-
I. Nasz, E. Adam, Recombinant adenovirus vectors for gene therapy and clinical trials, Acta Microbiol. Immunol. Hung. 48 (2001) 323-348.
-
(2001)
Acta Microbiol. Immunol. Hung.
, vol.48
, pp. 323-348
-
-
Nasz, I.1
Adam, E.2
-
33
-
-
0030710592
-
Insights into potential cellular mechanisms of cisplatin nephrotoxicity and their clinical application
-
M.K. Kuhlmann, G. Burkhardt, H. Kohler, Insights into potential cellular mechanisms of cisplatin nephrotoxicity and their clinical application, Nephrol. Dial. Transplant. 12 (1997) 2478-2480.
-
(1997)
Nephrol. Dial. Transplant.
, vol.12
, pp. 2478-2480
-
-
Kuhlmann, M.K.1
Burkhardt, G.2
Kohler, H.3
-
34
-
-
0026764141
-
Cisplatin and its analogues in the treatment of advanced breast cancer: A review
-
I.E. Smith, D.C. Talbot, Cisplatin and its analogues in the treatment of advanced breast cancer: a review, Br. J. Cancer 65 (1992) 787-793.
-
(1992)
Br. J. Cancer
, vol.65
, pp. 787-793
-
-
Smith, I.E.1
Talbot, D.C.2
|