Amino acids in a region of ataxin-1 outside of the polyglutamine tract influence the course of disease in SCA1 transgenic mice

NeuroMolecular Medicine

Volumn 1, Issue 1, 2002, Pages 33-42

  Skinner, Pamela J ^a   Vierra Green, Cynthia A ^a   Emamian, Effat ^a   Zoghbi, Huda Y ^c   Orr, Harry T ^a,b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Ataxia; Disease progression; Polyglutamine; SCA1

Indexed keywords

AMINO ACID; ATAXIN 1; BRAIN PROTEIN; POLYGLUTAMINE; UNCLASSIFIED DRUG; ATAXIN-1; NERVE PROTEIN; NUCLEAR PROTEIN; PEPTIDE;

ALLELE; AMINO ACID SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE ACTIVITY; DISEASE COURSE; GENE IDENTIFICATION; GENE MUTATION; GENE OVEREXPRESSION; MOLECULAR BIOLOGY; MOUSE; NEUROPATHOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PURKINJE CELL; SCA1 GENE; SPINOCEREBELLAR DEGENERATION; TRANSGENIC MOUSE; AMINO ACID SUBSTITUTION; ANIMAL; CEREBELLUM; CHEMISTRY; GENETICS; MUTATION; PATHOLOGY; TIME;

ANIMALIA; MUS MUSCULUS;

AMINO ACID SUBSTITUTION; ANIMALS; CEREBELLUM; DISEASE PROGRESSION; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PURKINJE CELLS; SPINOCEREBELLAR ATAXIAS; TIME FACTORS;

EID: 0036364453     PISSN: 15351084     EISSN: None     Source Type: Journal    
DOI: 10.1385/NMM:1:1:33     Document Type: Article

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