메뉴 건너뛰기




Volumn 46, Issue 4 SPEC., 2002, Pages 375-384

The role of the Eph-ephrin signalling system in the regulation of developmental patterning

Author keywords

Eph receptor; Ephrin; Mouse knockout; Signalling; Zebrafish

Indexed keywords

EPHRIN; PROTEIN; PROTEIN EPH; UNCLASSIFIED DRUG; EPHRIN RECEPTOR; LIGAND;

EID: 0036356054     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (55)

References (103)
  • 1
    • 0035846911 scopus 로고    scopus 로고
    • The cytoplasmic domain of the ligand EphrinB2 is required for vascular morphogenesis but not cranial neural crest migration
    • ADAMS, R.H., DIELLA, F., HENNIG, S., HELMBACHER, F., DEUTSCH, U. and KLEIN, R. (2001). The Cytoplasmic Domain of the Ligand EphrinB2 Is Required for Vascular Morphogenesis but Not Cranial Neural Crest Migration. Cell 104: 57-69.
    • (2001) Cell , vol.104 , pp. 57-69
    • Adams, R.H.1    Diella, F.2    Hennig, S.3    Helmbacher, F.4    Deutsch, U.5    Klein, R.6
  • 2
    • 0033082959 scopus 로고    scopus 로고
    • Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
    • ADAMS, R.H., WILKINSON, G.A., WEISS, C., DIELLA, F., GALE, N.W., DEUTSCH, U., RISAU, W. and KLEIN, R. (1999). Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev. 13: 295-306.
    • (1999) Genes Dev. , vol.13 , pp. 295-306
    • Adams, R.H.1    Wilkinson, G.A.2    Weiss, C.3    Diella, F.4    Gale, N.W.5    Deutsch, U.6    Risau, W.7    Klein, R.8
  • 4
    • 0033966557 scopus 로고    scopus 로고
    • Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation
    • BECKER, E., HUYNH-DO, U., HOLLAND, S., PAWSON, T., DANIEL, T.O. and SKOLNIK, E.Y. (2000). Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation. Mol Cell Biol 20: 1537-1545.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1537-1545
    • Becker, E.1    Huynh-Do, U.2    Holland, S.3    Pawson, T.4    Daniel, T.O.5    Skolnik, E.Y.6
  • 5
    • 0028336810 scopus 로고
    • Cloning and characterisation of HTK a novel transmembrane tyrosine kinase of the EPH subfamily
    • BENNETT, BD., WANG, Z., KUANG, W.-J., WANG, A., GROOPMAN, J., GOEDDEL, DV. and SCADDEN, DT. (1994). Cloning and characterisation of HTK a novel transmembrane tyrosine kinase of the EPH subfamily. J. Biol Chem. 269: 14211-14218.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14211-14218
    • Bennett, B.D.1    Wang, Z.2    Kuang, W.-J.3    Wang, A.4    Groopman, J.5    Goeddel, D.V.6    Scadden, D.T.7
  • 6
    • 0034034802 scopus 로고    scopus 로고
    • Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina
    • BIRGBAUER, E., COWAN, C.A., SRETAVAN, D.W. and HENKEMEYER, M. (2000). Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development 127: 1231-1241.
    • (2000) Development , vol.127 , pp. 1231-1241
    • Birgbauer, E.1    Cowan, C.A.2    Sretavan, D.W.3    Henkemeyer, M.4
  • 7
    • 0034890255 scopus 로고    scopus 로고
    • Retinal axon growth cones respond to EphB extracellular domains as inhibitory axon guidance cues
    • BIRGBAUER, E., OSTER, S.F., SEVERIN, C.G. and SRETAVAN, D.W. (2001). Retinal axon growth cones respond to EphB extracellular domains as inhibitory axon guidance cues. Development 128: 3041-3048.
    • (2001) Development , vol.128 , pp. 3041-3048
    • Birgbauer, E.1    Oster, S.F.2    Severin, C.G.3    Sretavan, D.W.4
  • 8
    • 0029773888 scopus 로고    scopus 로고
    • Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 and the EPH-related receptor HEK2 promotes tyrosine kinase activity
    • BOHME, B., VANDENBOS, T., CERRETTI, D.P., PARK, L., HOTRICH, U., RUBSAMEN-WAIGMANN, H. and AND STREBHARD, K. (1996). Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 and the EPH-related receptor HEK2 promotes tyrosine kinase activity. J. Biol. Chem. 271: 24727-24752.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24727-24752
    • Bohme, B.1    Vandenbos, T.2    Cerretti, D.P.3    Park, L.4    Hotrich, U.5    Rubsamen-Waigmann, H.6    Strebhard, K.7
  • 9
    • 0031042791 scopus 로고    scopus 로고
    • Two Eph receptor tyrosine kinase ligands control axon growth and may be involved in the creation of the retinotectal map in the zebrafish
    • BRENNAN, C., MONSCHAU, B., LINDBERG, R., GUTHRIE, B., DRESCHER, U., BONHOEFFER, F. and HOLDER, N. (1997). Two Eph receptor tyrosine kinase ligands control axon growth and may be involved in the creation of the retinotectal map in the zebrafish. Development 124: 655-664.
    • (1997) Development , vol.124 , pp. 655-664
    • Brennan, C.1    Monschau, B.2    Lindberg, R.3    Guthrie, B.4    Drescher, U.5    Bonhoeffer, F.6    Holder, N.7
  • 10
    • 0033103887 scopus 로고    scopus 로고
    • EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains
    • BRUCKNER, K., PABLO, L.J., SCHEIFFELE, P., HERB, A., SEEBURG, P.H. and KLEIN, R. (1999). EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron 22: 511-524.
    • (1999) Neuron , vol.22 , pp. 511-524
    • Bruckner, K.1    Pablo, L.J.2    Scheiffele, P.3    Herb, A.4    Seeburg, P.H.5    Klein, R.6
  • 12
    • 0029961757 scopus 로고    scopus 로고
    • Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion
    • CHEN, J., NACHABAH, A., SCHERER, C., GANJU, P., REITH, A., BRONSON, R. and RULEY, H.E. (1996). Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion. Oncogene 12: 979-88.
    • (1996) Oncogene , vol.12 , pp. 979-988
    • Chen, J.1    Nachabah, A.2    Scherer, C.3    Ganju, P.4    Reith, A.5    Bronson, R.6    Ruley, H.E.7
  • 13
    • 0029086140 scopus 로고
    • Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map
    • CHENG, H.J., NAKAMOTO, M., BERGEMANN, A.D. and FLANAGAN, J.G. (1995). Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell 82: 371-81.
    • (1995) Cell , vol.82 , pp. 371-381
    • Cheng, H.J.1    Nakamoto, M.2    Bergemann, A.D.3    Flanagan, J.G.4
  • 14
    • 0033599042 scopus 로고    scopus 로고
    • The ephrin VAB-2/EFN-1 functions in neuronal signaling to regulate epidermal morphogenesis in C. elegans
    • CHIN-SANG, I.D., GEORGE, S.E., DING, M., MOSELEY, S.L., LYNCH, A.S. and CHISHOLM, A.D. (1999). The ephrin VAB-2/EFN-1 functions in neuronal signaling to regulate epidermal morphogenesis in C. elegans. Cell 99: 781-790.
    • (1999) Cell , vol.99 , pp. 781-790
    • Chin-Sang, I.D.1    George, S.E.2    Ding, M.3    Moseley, S.L.4    Lynch, A.S.5    Chisholm, A.D.6
  • 15
    • 0033598383 scopus 로고    scopus 로고
    • Phosphorylation at tyr-838 in the kinase domain of EphA8 modulates fyn binding to the tyr-615 site by enhancing tyrosine kinase activity
    • CHOI, S. and PARK, S. (1999). Phosphorylation at tyr-838 in the kinase domain of EphA8 modulates fyn binding to the tyr-615 site by enhancing tyrosine kinase activity [In Process Citation]. Oncogene 18: 5413-5422.
    • (1999) Oncogene , vol.18 , pp. 5413-5422
    • Choi, S.1    Park, S.2
  • 16
    • 0029416971 scopus 로고
    • Genomic organization and alternatively processed forms of Cek5, a receptor protein-tyrosine kinase of the Eph subfamily
    • CONNOR, R.J. and PASQUALE, E.B. (1995). Genomic organization and alternatively processed forms of Cek5, a receptor protein-tyrosine kinase of the Eph subfamily. Oncogene 11: 2429-38.
    • (1995) Oncogene , vol.11 , pp. 2429-2438
    • Connor, R.J.1    Pasquale, E.B.2
  • 18
    • 0035097270 scopus 로고    scopus 로고
    • Eph signalling functions downstream of Val to regulate cell sorting and boundary formation in the caudal hindbrain
    • COOKE, J.E., MOENS, C.B., ROTH, L.W., DURBIN, L., SHIOMI, K., BRENNAN, C., KIMMEL, C.B., WILSON, S.W. and HOLDER, N. (2001). Eph signalling functions downstream of Val to regulate cell sorting and boundary formation in the caudal hindbrain. Development 128: 571-580.
    • (2001) Development , vol.128 , pp. 571-580
    • Cooke, J.E.1    Moens, C.B.2    Roth, L.W.3    Durbin, L.4    Shiomi, K.5    Brennan, C.6    Kimmel, C.B.7    Wilson, S.W.8    Holder, N.9
  • 20
    • 0034981049 scopus 로고    scopus 로고
    • Morpholino antisense oligonucleotides: Tools for investigating vertebrate development
    • Reviews 1015
    • COREY, D.R. and ABRAMS, J.M. (2001). Morpholino antisense oligonucleotides: tools for investigating vertebrate development. Genome Biol. 2: REVIEWS 1015.
    • (2001) Genome Biol. , vol.2
    • Corey, D.R.1    Abrams, J.M.2
  • 22
    • 0035855819 scopus 로고    scopus 로고
    • The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals
    • COWAN, C.A. and HENKEMEYER, M. (2001). The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals. Nature 413: 174-179.
    • (2001) Nature , vol.413 , pp. 174-179
    • Cowan, C.A.1    Henkemeyer, M.2
  • 23
    • 0033715818 scopus 로고    scopus 로고
    • EphB2 guides axons at the midline and is necessary for normal vestibular function
    • COWAN, C.A., YOKOYAMA, N., BIANCHI, L.M., HENKEMEYER, M. and FRITZSCH, B. (2000). EphB2 guides axons at the midline and is necessary for normal vestibular function. Neuron 26: 417-430.
    • (2000) Neuron , vol.26 , pp. 417-430
    • Cowan, C.A.1    Yokoyama, N.2    Bianchi, L.M.3    Henkemeyer, M.4    Fritzsch, B.5
  • 24
    • 0033385502 scopus 로고    scopus 로고
    • Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion
    • DAVY, A., GALE, N.W., MURRAY, E.W., KLINGHOFFER, R.A., SORIANO, P., FEUERSTEIN, C. and ROBBINS, S.M. (1999). Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion. Genes Dev. 13: 3125-3135.
    • (1999) Genes Dev. , vol.13 , pp. 3125-3135
    • Davy, A.1    Gale, N.W.2    Murray, E.W.3    Klinghoffer, R.A.4    Soriano, P.5    Feuerstein, C.6    Robbins, S.M.7
  • 25
    • 0034676025 scopus 로고    scopus 로고
    • Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner
    • DAVY, A. and ROBBINS, S.M. (2000). Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner. EMBO J. 19: 5396-5405.
    • (2000) EMBO J. , vol.19 , pp. 5396-5405
    • Davy, A.1    Robbins, S.M.2
  • 26
    • 0034693857 scopus 로고    scopus 로고
    • Eph receptors and ephrin ligands: Embryogenesis to tumorigenesis
    • DODELET, V.C. and PASQUALE, E.B. (2000). Eph receptors and ephrin ligands: embryogenesis to tumorigenesis. Oncogene 19: 5614-5619.
    • (2000) Oncogene , vol.19 , pp. 5614-5619
    • Dodelet, V.C.1    Pasquale, E.B.2
  • 27
    • 0033527649 scopus 로고    scopus 로고
    • A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A
    • DODELET, V.C., PAZZAGLI, C., ZISCH, A.H., HAUSER, C.A. and PASQUALE, E.B. (1999). A Novel Signaling Intermediate, SHEP1, Directly Couples Eph Receptors to R-Ras and Rap1A. J. Biol. Chem. 274: 31941-31946.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31941-31946
    • Dodelet, V.C.1    Pazzagli, C.2    Zisch, A.H.3    Hauser, C.A.4    Pasquale, E.B.5
  • 29
    • 0029082312 scopus 로고
    • In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases
    • DRESCHER, U., KREMOSER, C., HANDWERKER, C., LOSCHINGER, J., NODA, M. and BONHOEFFER, F. (1995). In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases. Cell 82: 359-70.
    • (1995) Cell , vol.82 , pp. 359-370
    • Drescher, U.1    Kremoser, C.2    Handwerker, C.3    Loschinger, J.4    Noda, M.5    Bonhoeffer, F.6
  • 32
    • 0029867243 scopus 로고    scopus 로고
    • A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high affinity interaction with p59fyn
    • ELLIS, C., KASMI, F., GANJU, P., WALLS, E., PANAYOTOU, G. and REITH, A.D. (1996). A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high affinity interaction with p59fyn. Oncogene 12: 1727-36.
    • (1996) Oncogene , vol.12 , pp. 1727-1736
    • Ellis, C.1    Kasmi, F.2    Ganju, P.3    Walls, E.4    Panayotou, G.5    Reith, A.D.6
  • 33
    • 0034790653 scopus 로고    scopus 로고
    • Downregulation of the ras-mitogen-activated protein kinase pathway by the ephb2 receptor tyrosine kinase is required for ephrin-induced neurite retraction
    • ELOWE, S., HOLLAND, S.J., KULKARNI, S. and PAWSON, T. (2001). Downregulation of the ras-mitogen-activated protein kinase pathway by the ephb2 receptor tyrosine kinase is required for ephrin-induced neurite retraction. Mol. Cell Biol. 21: 7429-7441.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7429-7441
    • Elowe, S.1    Holland, S.J.2    Kulkarni, S.3    Pawson, T.4
  • 34
    • 0033681554 scopus 로고    scopus 로고
    • Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping
    • FELDHEIM, D.A., KIM, Y.I., BERGEMANN, A.D., FRISEN, J., BARBACID, M. and FLANAGAN, J.G. (2000). Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping [see comments]. Neuron 25: 563-574.
    • (2000) Neuron , vol.25 , pp. 563-574
    • Feldheim, D.A.1    Kim, Y.I.2    Bergemann, A.D.3    Frisen, J.4    Barbacid, M.5    Flanagan, J.G.6
  • 35
    • 0033757699 scopus 로고    scopus 로고
    • Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers
    • FENG, G., LASKOWSKI, M.B., FELDHEIM, D.A., WANG, H., LEWIS, R., FRISEN, J., FLANAGAN, J.G. and SANES, J.R. (2000). Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers. Neuron 25: 295-306.
    • (2000) Neuron , vol.25 , pp. 295-306
    • Feng, G.1    Laskowski, M.B.2    Feldheim, D.A.3    Wang, H.4    Lewis, R.5    Frisen, J.6    Flanagan, J.G.7    Sanes, J.R.8
  • 36
    • 0031922119 scopus 로고    scopus 로고
    • The ephrins and Eph receptors in neural development
    • FLANAGAN, J.G. and VANDERHAEGHEN, P. (1998). The ephrins and Eph receptors in neural development. Annu Rev Neurosci 21: 309-45.
    • (1998) Annu. Rev. Neurosci. , vol.21 , pp. 309-345
    • Flanagan, J.G.1    Vanderhaeghen, P.2
  • 37
    • 0032006223 scopus 로고    scopus 로고
    • Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system
    • FRISEN, J., YATES, P.A., MCLAUGHLIN, T., FRIEDMAN, G.C., O'LEARY, D.D. and BARBACID, M. (1998). Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system. Neuron 20: 235-43.
    • (1998) Neuron , vol.20 , pp. 235-243
    • Frisen, J.1    Yates, P.A.2    Mclaughlin, T.3    Friedman, G.C.4    O'Leary, D.D.5    Barbacid, M.6
  • 39
    • 0032489430 scopus 로고    scopus 로고
    • The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans
    • GEORGE, S.E., SIMOKAT, K., HARDIN, J. and CHISHOLM, A.D. (1998). The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans. Cell 92: 633-43.
    • (1998) Cell , vol.92 , pp. 633-643
    • George, S.E.1    Simokat, K.2    Hardin, J.3    Chisholm, A.D.4
  • 40
    • 0033197535 scopus 로고    scopus 로고
    • Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development
    • GERETY, S.S., WANG, H.U., CHEN, Z.F. and ANDERSON, D.J. (1999). Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol. Cell 4: 403-414.
    • (1999) Mol. Cell , vol.4 , pp. 403-414
    • Gerety, S.S.1    Wang, H.U.2    Chen, Z.F.3    Anderson, D.J.4
  • 41
    • 0033485972 scopus 로고    scopus 로고
    • Retinotectal maps: Molecules, models and misplaced data
    • GOODHILL, G.J. and RICHARDS, L.J. (1999). Retinotectal maps: molecules, models and misplaced data. Trends Neurosci. 22: 529-534.
    • (1999) Trends Neurosci. , vol.22 , pp. 529-534
    • Goodhill, G.J.1    Richards, L.J.2
  • 42
    • 0034960682 scopus 로고    scopus 로고
    • The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent manner
    • GU, C. and PARK, S. (2001). The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent manner. Mol. Cell Biol. 21: 4579-4597.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4579-4597
    • Gu, C.1    Park, S.2
  • 43
    • 0029780534 scopus 로고    scopus 로고
    • A new member of the Eph family of receptors that lacks protein tyrosine kinase activity
    • GURNIAK, C.B. and BERG, L.J. (1996). A new member of the Eph family of receptors that lacks protein tyrosine kinase activity. Oncogene 13: 777-86.
    • (1996) Oncogene , vol.13 , pp. 777-786
    • Gurniak, C.B.1    Berg, L.J.2
  • 44
    • 0034714357 scopus 로고    scopus 로고
    • Regulated cleavage of a contact-mediated axon repellent
    • HATTORI, M., OSTERFIELD, M. and FLANAGAN, J.G. (2000). Regulated cleavage of a contact-mediated axon repellent. Science 289: 1360-1365.
    • (2000) Science , vol.289 , pp. 1360-1365
    • Hattori, M.1    Osterfield, M.2    Flanagan, J.G.3
  • 45
    • 0033845946 scopus 로고    scopus 로고
    • Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons
    • HELMBACHER, F., SCHNEIDER-MAUNOURY, S., TOPILKO, P., TIRET, L. and CHARNAY, P. (2000). Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons. Development 127: 3313-3324.
    • (2000) Development , vol.127 , pp. 3313-3324
    • Helmbacher, F.1    Schneider-Maunoury, S.2    Topilko, P.3    Tiret, L.4    Charnay, P.5
  • 46
    • 0344816258 scopus 로고    scopus 로고
    • Nuk controls pathfinding of commissural axons in the mammalian central nervous system
    • HENKEMEYER, M., ORIOLI, D., HENDERSON, J.T., SAXTON, T.M., RODER, J., PAWSON, T. and KLEIN, R. (1996). Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell 86: 35-46.
    • (1996) Cell , vol.86 , pp. 35-46
    • Henkemeyer, M.1    Orioli, D.2    Henderson, J.T.3    Saxton, T.M.4    Roder, J.5    Pawson, T.6    Klein, R.7
  • 47
    • 0023607638 scopus 로고
    • A novel putative tyrosine kinase receptor encoded bythe eph gene
    • HIRAI, H., MARU, Y., HAGIWARA, K., NISHIDA, J. and TAKAKU, F. (1987). A novel putative tyrosine kinase receptor encoded bythe eph gene. Science 238: 1717-20.
    • (1987) Science , vol.238 , pp. 1717-1720
    • Hirai, H.1    Maru, Y.2    Hagiwara, K.3    Nishida, J.4    Takaku, F.5
  • 48
    • 0034892013 scopus 로고    scopus 로고
    • Identification of ephrin-A3 and novel genes specific to the midbrain-MHB in embryonic zebrafish by ordered differential display
    • HIRATE, Y., MIEDA, M., HARADA, T., YAMASU, K. and OKAMOTO, H. (2001). Identification of ephrin-A3 and novel genes specific to the midbrain-MHB in embryonic zebrafish by ordered differential display. Mech. Dev. 107: 83-96.
    • (2001) Mech. Dev. , vol.107 , pp. 83-96
    • Hirate, Y.1    Mieda, M.2    Harada, T.3    Yamasu, K.4    Okamoto, H.5
  • 50
    • 0029851690 scopus 로고    scopus 로고
    • Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
    • HOLLAND, S.J., GALE, N.W., MBAMALU, G., YANCOPOULOS, G.D., HENKEMEYER, M. and PAWSON, T. (1996). Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands. Nature 383: 722-725.
    • (1996) Nature , vol.383 , pp. 722-725
    • Holland, S.J.1    Gale, N.W.2    Mbamalu, G.3    Yancopoulos, G.D.4    Henkemeyer, M.5    Pawson, T.6
  • 51
    • 0034626791 scopus 로고    scopus 로고
    • Regulation of repulsion versus adhesion by different splice forms of an Eph receptor
    • HOLMBERG, J., CLARKE, D.L. and FRISEN J. (2000). Regulation of repulsion versus adhesion by different splice forms of an Eph receptor. Nature 408: 203-206.
    • (2000) Nature , vol.408 , pp. 203-206
    • Holmberg, J.1    Clarke, D.L.2    Frisen, J.3
  • 52
    • 0035794136 scopus 로고    scopus 로고
    • An ephrinA-dependent signaling pathway controls integrin function and is linked to the tyrosine phosphorylation of a 120 kDa protein
    • HUAI, J. and DRESCHER, U. (2001). An ephrinA-dependent signaling pathway controls integrin function and is linked to the tyrosine phosphorylation of a 120 kDa protein. J. Biol. Chem. 276: 6689-6694.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6689-6694
    • Huai, J.1    Drescher, U.2
  • 53
    • 0033560751 scopus 로고    scopus 로고
    • Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins
    • HUYNH-DO, U., STEIN, E., LANE, A.A., LIU, H., CERRETTI, D.P. and DANIEL, T.O. (1999). Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins. Embo J 18: 2165-2173.
    • (1999) EMBO J. , vol.18 , pp. 2165-2173
    • Huynh-Do, U.1    Stein, E.2    Lane, A.A.3    Liu, H.4    Cerretti, D.P.5    Daniel, T.O.6
  • 54
    • 0030935627 scopus 로고    scopus 로고
    • Selective expression of the receptor tyrosine kinase, HTK, on human erythroid progenitor cells
    • INADA, T., IWAMA, A., SAKANO, S., OHNO, M., SAWADA, K. and SUDA, T. (1997). Selective expression of the receptor tyrosine kinase, HTK, on human erythroid progenitor cells. Blood 89: 2757-65.
    • (1997) Blood , vol.89 , pp. 2757-2765
    • Inada, T.1    Iwama, A.2    Sakano, S.3    Ohno, M.4    Sawada, K.5    Suda, T.6
  • 55
    • 0031906668 scopus 로고    scopus 로고
    • Loss of cell adhesion in Xenopus laevis embryos mediated by the cytoplasmic domain of XLerk, an erythropoietin-producing hepatocellular ligand
    • JONES, T.L., CHONG, L.D., KIM, J., XU, R.H., KUNG, H.F. and DAAR, I.O. (1998). Loss of cell adhesion in Xenopus laevis embryos mediated by the cytoplasmic domain of XLerk, an erythropoietin-producing hepatocellular ligand. Proc Natl Acad Sci USA 95: 576-81.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 576-581
    • Jones, T.L.1    Chong, L.D.2    Kim, J.3    Xu, R.H.4    Kung, H.F.5    Daar, I.O.6
  • 56
    • 0033598224 scopus 로고    scopus 로고
    • Bidirectional signals establish boundaries
    • KLEIN, R. (1999). Bidirectional signals establish boundaries. Curr. Biol. 9: R691-R694.
    • (1999) Curr. Biol. , vol.9
    • Klein, R.1
  • 57
    • 0035313727 scopus 로고    scopus 로고
    • Excitatory Eph receptors and adhesive ephrin ligands
    • KLEIN, R. (2001). Excitatory Eph receptors and adhesive ephrin ligands. Curr. Opin. Cell Biol. 13: 196-203.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 196-203
    • Klein, R.1
  • 59
    • 0035137449 scopus 로고    scopus 로고
    • Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo
    • KULLANDER, K., MATHER, N.K., DIELLA, F., DOTTORI, M., BOYD, A.W. and KLEIN, R. (2001b). Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo. Neuron 29: 73-84.
    • (2001) Neuron , vol.29 , pp. 73-84
    • Kullander, K.1    Mather, N.K.2    Diella, F.3    Dottori, M.4    Boyd, A.W.5    Klein, R.6
  • 62
    • 0034954755 scopus 로고    scopus 로고
    • Expression of Eph receptors in skeketal muscle and their localization at the neuromuscular junction
    • LAI, K.O., IP, F.C., CHEUNG, J., FU, A.K. and IP, N.Y. (2001). Expression of Eph receptors in skeketal muscle and their localization at the neuromuscular junction. Mol. Cell Neurosci. 17: 1034-1047.
    • (2001) Mol. Cell. Neurosci. , vol.17 , pp. 1034-1047
    • Lai, K.O.1    Ip, F.C.2    Cheung, J.3    Fu, A.K.4    Ip, N.Y.5
  • 63
    • 0030693356 scopus 로고    scopus 로고
    • A coherent nomenclature for Eph receptors and their ligands
    • LEMKE, G. (1997). A Coherent Nomenclature for Eph Receptors and Their Ligands. Mol Cell Neurosci 9: 331-2.
    • (1997) Mol. Cell. Neurosci. , vol.9 , pp. 331-332
    • Lemke, G.1
  • 65
    • 0033525063 scopus 로고    scopus 로고
    • The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif
    • LIN, D., GISH, G.D., SONGYANG, Z. and PAWSON, T. (1999). The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif. J. Biol. Chem. 274: 3726-3733.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3726-3733
    • Lin, D.1    Gish, G.D.2    Songyang, Z.3    Pawson, T.4
  • 66
    • 0035815305 scopus 로고    scopus 로고
    • Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction
    • LU, Q., SUN, E.E., KLEIN, R.S. and FLANAGAN, J.G. (2001). Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell 105: 69-79.
    • (2001) Cell , vol.105 , pp. 69-79
    • Lu, Q.1    Sun, E.E.2    Klein, R.S.3    Flanagan, J.G.4
  • 68
    • 0023741167 scopus 로고
    • Evolution, expression, and chromosomal location of a novel receptor tyrosine kinase gene, eph
    • MARU, Y., HIRAI, H., YOSHIDA, M.C. and TAKAKU, F. (1988). Evolution, expression, and chromosomal location of a novel receptor tyrosine kinase gene, eph. Molecular & Cellular Biology 8: 3770-6.
    • (1988) Molecular & Cellular Biology , vol.8 , pp. 3770-3776
    • Maru, Y.1    Hirai, H.2    Yoshida, M.C.3    Takaku, F.4
  • 69
    • 0033168047 scopus 로고    scopus 로고
    • Eph receptors and ephrins restrict cell intermingling and communication
    • MELLITZER, G., XU, Q. and WILKINSON, D.G. (1999). Eph receptors and ephrins restrict cell intermingling and communication. Nature 400: 77-81.
    • (1999) Nature , vol.400 , pp. 77-81
    • Mellitzer, G.1    Xu, Q.2    Wilkinson, D.G.3
  • 70
    • 0035253399 scopus 로고    scopus 로고
    • Ephrin-A6, a new ligand for EphA receptors in the developing visual system
    • MENZEL, P., VALENCIA, F., GODEMENT, P., DODELET, V.C. and PASQUALE, E.B. (2001). Ephrin-A6, a New Ligand for EphA Receptors in the Developing Visual System. Dev. Biol. 230: 74-88.
    • (2001) Dev. Biol. , vol.230 , pp. 74-88
    • Menzel, P.1    Valencia, F.2    Godement, P.3    Dodelet, V.C.4    Pasquale, E.B.5
  • 71
    • 0033785409 scopus 로고    scopus 로고
    • Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation
    • MIAO, H., BURNETT, E., KINCH, M., SIMON, E. and WANG, B. (2000). Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation. Nat. Cell Biol. 2: 62-69.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 62-69
    • Miao, H.1    Burnett, E.2    Kinch, M.3    Simon, E.4    Wang, B.5
  • 74
    • 0035060608 scopus 로고    scopus 로고
    • Involvement of EphA2 in the formation of the tail notochord via interaction with ephrinA1
    • NARUSE-NAKAJIMA, C., ASANO, M. and IWAKURA, Y. (2001). Involvement of EphA2 in the formation of the tail notochord via interaction with ephrinA1. Mech. Dev. 102: 95-105.
    • (2001) Mech. Dev. , vol.102 , pp. 95-105
    • Naruse-Nakajima, C.1    Asano, M.2    Iwakura, Y.3
  • 75
    • 0031786126 scopus 로고    scopus 로고
    • Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrin-B2 during mammary gland morphogenesis
    • NIKOLOVA, Z., DJONOV, V., ZUERCHER, G., ANDRES, A.C. and ZIEMIECKI, A. (1998). Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrin-B2 during mammary gland morphogenesis. J Cell Sci 111: 2741-51.
    • (1998) J. Cell Sci. , vol.111 , pp. 2741-2751
    • Nikolova, Z.1    Djonov, V.2    Zuercher, G.3    Andres, A.C.4    Ziemiecki, A.5
  • 77
    • 0029858435 scopus 로고    scopus 로고
    • Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation
    • ORIOLI, D., HENKEMEYER, M., LEMKE, G., KLEIN, R. and PAWSON, T. (1996). Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 15: 6035-6049.
    • (1996) EMBO J. , vol.15 , pp. 6035-6049
    • Orioli, D.1    Henkemeyer, M.2    Lemke, G.3    Klein, R.4    Pawson, T.5
  • 78
    • 0034072748 scopus 로고    scopus 로고
    • Expression of Eph receptors and ephrins is differentially regulated by E-cadherin
    • ORSULIC, S. and KEMLER, R. (2000). Expression of Eph receptors and ephrins is differentially regulated by E-cadherin. J. Cell Sci. 113: 1793-1802.
    • (2000) J. Cell Sci. , vol.113 , pp. 1793-1802
    • Orsulic, S.1    Kemler, R.2
  • 79
    • 0033152926 scopus 로고    scopus 로고
    • Genomic structure of the EPHA1 receptor tyrosine kinase gene
    • OWSHALIMPUR, D. and KELLEY, M.J. (1999). Genomic structure of the EPHA1 receptor tyrosine kinase gene. Mol. Cell Probes 13: 169-173.
    • (1999) Mol. Cell. Probes , vol.13 , pp. 169-173
    • Owshalimpur, D.1    Kelley, M.J.2
  • 80
    • 0030957996 scopus 로고    scopus 로고
    • Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors
    • PARK, S., FRISEN, J. and BARBACID, M. (1997). Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors. Embo J 16: 3106-14.
    • (1997) EMBO J. , vol.16 , pp. 3106-3114
    • Park, S.1    Frisen, J.2    Barbacid, M.3
  • 81
    • 0032808087 scopus 로고    scopus 로고
    • Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection
    • PICKER, A., BRENNAN, C., REIFERS, F., CLARKE, J.D., HOLDER, N. and BRAND, M. (1999). Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection. Development 126: 2967-2978.
    • (1999) Development , vol.126 , pp. 2967-2978
    • Picker, A.1    Brennan, C.2    Reifers, F.3    Clarke, J.D.4    Holder, N.5    Brand, M.6
  • 82
    • 0034255005 scopus 로고    scopus 로고
    • Malformation of the functional organization of somatosensory cortex in adult ephrin-A5 knock-out mice revealed by in vivo functional imaging
    • PRAKASH, N., VANDERHAEGHEN, P., COHEN-CORY, S., FRISEN, J., FLANAGAN, J.G. and FROSTIG, R.D. (2000). Malformation of the functional organization of somatosensory cortex in adult ephrin-A5 knock-out mice revealed by in vivo functional imaging. J. Neurosci. 20: 5841-5847.
    • (2000) J. Neurosci. , vol.20 , pp. 5841-5847
    • Prakash, N.1    Vanderhaeghen, P.2    Cohen-Cory, S.3    Frisen, J.4    Flanagan, J.G.5    Frostig, R.D.6
  • 83
    • 0035875044 scopus 로고    scopus 로고
    • Signaling downstream of Eph receptors and ephrin ligands
    • SCHMUCKER, D. and ZIPURSKY, S.L. (2001). Signaling downstream of Eph receptors and ephrin ligands. Cell 105: 701-704.
    • (2001) Cell , vol.105 , pp. 701-704
    • Schmucker, D.1    Zipursky, S.L.2
  • 85
    • 0029844406 scopus 로고    scopus 로고
    • Developmental expression and distinctive tyrosine phosphorylation of the Eph-related receptor tyrosine kinase Cek9
    • SOANS, C., HOLASH, J.A., PAVLOVA, Y. and PASQUALE, E.B. (1996). Developmental expression and distinctive tyrosine phosphorylation of the Eph-related receptor tyrosine kinase Cek9. J. Cell Biol. 135: 781-95.
    • (1996) J. Cell Biol. , vol.135 , pp. 781-795
    • Soans, C.1    Holash, J.A.2    Pavlova, Y.3    Pasquale, E.B.4
  • 86
    • 0032031705 scopus 로고    scopus 로고
    • Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses
    • STEIN, E., LANE, A.A., CERRETTI, D.P., SCHOECKLMANN, H.O., SCHROFF, A.D., VAN ETTEN, R.L. and DANIEL, T.O. (1998). Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses. Genes Dev 12: 667-78.
    • (1998) Genes Dev. , vol.12 , pp. 667-678
    • Stein, E.1    Lane, A.A.2    Cerretti, D.P.3    Schoecklmann, H.O.4    Schroff, A.D.5    Van Etten, R.L.6    Daniel, T.O.7
  • 87
    • 0031952696 scopus 로고    scopus 로고
    • Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under direct transcriptional control of Krox-20
    • THEIL, T., FRAIN, M., GILARDI-HEBENSTREIT, P., FLENNIKEN, A., CHARNAY, P. and WILKINSON, D.G. (1998). Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under direct transcriptional control of Krox-20. Development 125: 443-52.
    • (1998) Development , vol.125 , pp. 443-452
    • Theil, T.1    Frain, M.2    Gilardi-Hebenstreit, P.3    Flenniken, A.4    Charnay, P.5    Wilkinson, D.G.6
  • 89
    • 0034678363 scopus 로고    scopus 로고
    • Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase
    • WAHL, S., BARTH, H., CIOSSEK, T., AKTORIES, K. and MUELLER, B.K. (2000). Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase. J. Cell Biol 149: 263-270.
    • (2000) J. Cell Biol. , vol.149 , pp. 263-270
    • Wahl, S.1    Barth, H.2    Ciossek, T.3    Aktories, K.4    Mueller, B.K.5
  • 90
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • WANG, H.U., CHEN, Z.F. and ANDERSON, D.J. (1998). Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93: 741-53.
    • (1998) Cell , vol.93 , pp. 741-753
    • Wang, H.U.1    Chen, Z.F.2    Anderson, D.J.3
  • 91
    • 0033400803 scopus 로고    scopus 로고
    • Multiple ephrins control cell organization in C. elegans using kinase-dependent and -independent functions of the VAB-1 Eph receptor
    • WANG, X., ROY, P.J., HOLLAND, S.J., ZHANG, L.W., CULOTTI, J.G. and PAWSON, T. (1999). Multiple ephrins control cell organization in C. elegans using kinase-dependent and -independent functions of the VAB-1 Eph receptor. Mol. Cell 4: 903-913.
    • (1999) Mol. Cell , vol.4 , pp. 903-913
    • Wang, X.1    Roy, P.J.2    Holland, S.J.3    Zhang, L.W.4    Culotti, J.G.5    Pawson, T.6
  • 92
    • 0026500682 scopus 로고
    • Molecular cloning of HEK, the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines
    • WICKS, I.P., WILKINSON, D., SALVARIS, E. and BOYD, A.W. (1992). Molecular cloning of HEK, the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines. Proc. Natl. Acad. Sci. USA 89:1611-5.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1611-1615
    • Wicks, I.P.1    Wilkinson, D.2    Salvaris, E.3    Boyd, A.W.4
  • 93
    • 0035287473 scopus 로고    scopus 로고
    • Multiple roles of EPH receptors and ephrins in neural development
    • WILKINSON, D.G. (2001). Multiple roles of EPH receptors and ephrins in neural development. Nat. Rev. Neurosci. 2: 155-164.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 155-164
    • Wilkinson, D.G.1
  • 94
    • 0030296507 scopus 로고    scopus 로고
    • Disruption of cell adhesion in Xenopus embryos by Pagliaccio, an Eph-class receptor tyrosine kinase
    • WINNING, R.S., SCALES, J.B. and SARGENT, T.D. (1996). Disruption of cell adhesion in Xenopus embryos by Pagliaccio, an Eph-class receptor tyrosine kinase. Dev. Biol. 179: 309-319.
    • (1996) Dev. Biol. , vol.179 , pp. 309-319
    • Winning, R.S.1    Scales, J.B.2    Sargent, T.D.3
  • 95
    • 0035929146 scopus 로고    scopus 로고
    • Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase bythe unphosphorylatedjuxtamembrane region
    • WYBENGA-GROOT, L.E., BASKIN, B., ONG, S.H., TONG, J., PAWSON, T. and SICHERI, F. (2001). Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase bythe unphosphorylatedjuxtamembrane region. Cell 106: 745-757.
    • (2001) Cell , vol.106 , pp. 745-757
    • Wybenga-Groot, L.E.1    Baskin, B.2    Ong, S.H.3    Tong, J.4    Pawson, T.5    Sicheri, F.6
  • 96
    • 13344261393 scopus 로고
    • Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain
    • XU, Q., ALLDUS, G., HOLDER, N. and WILKINSON, D.G. (1995). Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain. Development 121: 4005-16.
    • (1995) Development , vol.121 , pp. 4005-4016
    • Xu, Q.1    Alldus, G.2    Holder, N.3    Wilkinson, D.G.4
  • 98
    • 0034256340 scopus 로고    scopus 로고
    • Laminar specificity of local circuits in barrel cortex of ephrin-A5 knockout mice
    • YABUTA, N.H., BUTLER, A.K. and CALLAWAY, E.M. (2000). Laminar Specificity of Local Circuits in Barrel Cortex of Ephrin-A5 Knockout Mice. J. Neurosci. (Online.) 20: RC88
    • (2000) J. Neurosci. (Online) , vol.20
    • Yabuta, N.H.1    Butler, A.K.2    Callaway, E.M.3
  • 99
    • 0035132793 scopus 로고    scopus 로고
    • Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline
    • YOKOYAMA, N., ROMERO, M.I., COWAN, C.A., GALVAN, P., HELMBACHER, F., CHARNAY, P., PARADA, L.F. and HENKEMEYER, M. (2001). Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline. Neuron 29: 85-97.
    • (2001) Neuron , vol.29 , pp. 85-97
    • Yokoyama, N.1    Romero, M.I.2    Cowan, C.A.3    Galvan, P.4    Helmbacher, F.5    Charnay, P.6    Parada, L.F.7    Henkemeyer, M.8
  • 100
    • 0035811562 scopus 로고    scopus 로고
    • Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor
    • YU, H.H., ZISCH, A.H., DODELET, V.C. and PASQUALE, E.B. (2001). Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor. Oncogene 20: 3995-4006.
    • (2001) Oncogene , vol.20 , pp. 3995-4006
    • Yu, H.H.1    Zisch, A.H.2    Dodelet, V.C.3    Pasquale, E.B.4
  • 101
    • 0033559449 scopus 로고    scopus 로고
    • Specification of distinct dopaminergic neural pathways: Roles of the Eph family receptor EphB1 and ligand ephrin-B2
    • YUE, Y., WIDMER, D.A., HALLADAY, A.K., CERRETTI, D.P., WAGNER, G.C., DREYER, J.L. and ZHOU, R. (1999). Specification of distinct dopaminergic neural pathways: roles of the Eph family receptor EphB1 and ligand ephrin-B2. J. Neurosci. 19: 2090-2101.
    • (1999) J. Neurosci. , vol.19 , pp. 2090-2101
    • Yue, Y.1    Widmer, D.A.2    Halladay, A.K.3    Cerretti, D.P.4    Wagner, G.C.5    Dreyer, J.L.6    Zhou, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.