Regulation of microvascular permeability by vascular endothelial growth factors

Journal of Anatomy

Volumn 200, Issue 6, 2002, Pages 581-597

  Bates, D O ^a   Hillman, N J ^b   Williams, B ^b   Neal, C R ^a   Pocock, T M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Calcium; Endothelium; Hydraulic conductivity; Transcellular gaps; TRPC channels; Vascular permeability; VEGF; VVO

Indexed keywords

CALCIUM ION; CATION CHANNEL; DIACYLGLYCEROL; PHOSPHOLIPASE C; TYROSINE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; BLOOD VESSEL PERMEABILITY; CALCIUM TRANSPORT; CELL JUNCTION; CELL MEMBRANE TRANSPORT; CELL ORGANELLE; CELL VACUOLE; ENDOTHELIUM CELL; ENZYME ACTIVATION; FATTY ACID SYNTHESIS; HUMAN; HUMAN CELL; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW;

ANIMALS; CAPILLARY PERMEABILITY; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; HUMANS; LYMPHOKINES; MODELS, BIOLOGICAL; NEOVASCULARIZATION, PHYSIOLOGIC; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1; VASCULAR ENDOTHELIAL GROWTH FACTORS;

ANIMALIA;

EID: 0036316243     PISSN: 00218782     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-7580.2002.00066.x     Document Type: Review

References (125)

1. The permeability of blood capillary sprouts and newly formed blood capillaries as compared to that of older capillaries
2. Pathways through the intercellular clefts of frog mesenteric capillaries
3. Role of vascular endothelial growth factor in diabetic vascular complications
4. Permeability characteristics of cultured endothelial cell monolayers
5. Vascular endothelial growth factor increases hydraulic conductivity of isolated perfused microvessels
6. 2+-dependent pathway
7. The chronic effect of vascular endothelial growth factor on individually perfused frog mesenteric microvessels
8. Vascular endothelial growth factor and microvascular permeability
9. Vascular endothelial growth factor increases Rana vascular permeability and compliance by different signalling pathways
10. Inositol trisphosphate and calcium signalling
11. 2+ and von Willebrand factor release in human endothelial cells
12. Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas
13. Intravital video-capillaroscopy for the study of the microcirculation in psoriasis
14. Vascular endothelial growth factor enhances atherosclerotic plaque progression
15. Observations on changes in blood vascular endothelium in the living animal
16. Inflammatory changes in permeability and ultrastructure of single vessels in the frog mesenteric microcirculation
17. Characterization of the increase in vascular permeability induced by vascular permeability factor in vivo
18. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis
19. Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in normal and atherosclerotic human arteries
20. A review of the microcirculation of adipose tissue: Anatomic, metabolic, and angiogenic perspectives
21. Cytosolic calcium changes in endothelial cells induced by a protein product of human gliomas containing vascular permeability factor activity
22. Further characterization of malignant glioma-derived vascular perme-ability factor
23. Techniques in microcirculation: Measurement of permeability, pressure and flow
24. Mechanics and Thermodynamics of Transcapillary Exchange
25. Modulation of venular microvessel permeability by calcium influx into endothelial cells
26. Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms
27. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
28. Interendothelial junctions and their role in the control of angiogenesis, vascular permeability and leukocyte transmigration
29. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
30. VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases
31. The vesiculo-vacuolar organelle (VVO): A distinct endothelial cell structure that provides a transcellular pathway for macromolecular extravasation
32. Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis
33. Vascular Endothelial Growth Factor Induces Endothelial Fenestrations In vitro
34. Purification and biological properties of vasculotropin, a new angiogenic cytokine
35. Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor, histamine, and serotonin
36. Reinterpretation of endothelial cell gaps induced by vasoactive mediators in guinea-pig, mouse and rat: Many are transcellular pores
37. Pathways of macromolecular extravasation across microvascular endothelium in response to VPF/VEGF and other vasoactive mediators
38. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
39. Vascular endothelial growth factor, a specific regulator of angiogenesis
40. Role of vascular endothelial growth factor in regulation of physiological angiogenesis
41. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
42. Structural mechanism of vascular endothelial growth factor (VEGF) induced acute microvessel hyperpermeability
43. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
44. Tyrosine phosphorylation of the vascular endothelial-growth-factor receptor-2 (VEGFR-2) is modulated by Rho proteins
45. Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation
46. Measurement of cytoplasmic calcium in single microvessels with increased permeability
47. Microvessel endothelial cell ultrastructure after vascular endothelial growth factor-C (VEGF-C) induced chronically increased Lp
48. Differential effects on Microvascular Hydraulic Conductivity (Lp) of Vascular Endothelial Growth Factor C (VEGF-C) and Placental Growth Factor-1 (PIGF-1)
49. VEGF induces hyperpermeability by a direct action on endothelial cells
50. VEGF-A induced hyperpermeability of blood-retinal barrier endothelium in vivo is predominantly associated with pinocytotic vesicular transport and not with formation of fenestrations. Vascular endothelial growth factor-A
51. Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
52. The vascular endothelial growth factor family: Identification of a fourth molecular species and characterization of alternative splicing of RNA
53. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
54. Development of the microcirculation: Capillary growth and adaptation
55. Angiogenesis in skeletal and cardiac muscle
56. Ets-1 regulates angiogenesis by inducing the expression of urokinase-type plasminogen activator and matrix metalloproteinase-1 and the migration of vascular endothelial cells
57. 183, a novel spliced variant of vascular endothelial growth factor
58. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
59. Vascular permeability factor, an endothelial cell mitogen related to PDGF
60. Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis
61. The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency
62. Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries
63. Effect of VEGF on retinal microvascular endothelial hydraulic conductivity: The role of NO
64. Exchange of substances through the capillary walls
65. Vascular endothelial growth factor is a secreted angiogenic mitogen
66. An analysis of the permeability of a fenestra
67. Characterization of signal transduction pathways in human bone marrow endothelial cells
68. Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart
69. Endothelial contraction induced by histamine-type mediators: An electron microscopic study
70. A development of the Landis technique for measuring the filtration coefficient of individual capillaries in the frog mesentery
71. Fluid movements through capillary walls
72. Steady-state fluid filtration at different capillary pressures in perfused frog mesenteric capillaries
73. Transport of macromolecules through microvascular walls
74. Microvascular permeability
75. Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea pigs
76. Vascular permeability factor/vascular endothelial growth factor-mediated signaling in mouse mesentery vascular endothelium
77. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
78. Fenestration of tenosynovial capillaries
79. Transcellular openings through microvascular walls in acutely inflamed frog mesentery
80. Vascular endothelial growth factor (VEGF) increases permeability by inducing openings through endothelial cells
81. Differing effects of Vascular Endothelial Growth Factor (VEGF) on the ultrastructure of mesenteric microvessels of frog and rat
82. Ultrastructural changes in microvascular endothelium associated with increased permeability
83. Ferritin as a tracer when used to increase permeability in frog microvessels
84. Vascular Endothelial Growth Factor produces a greater transient increase in hydraulic permeability at lower rather than at higher capillary pressures
85. Vascular endothelial growth factor (VEGF) and its receptors
86. Thromboxane A (2) regulation of endothelial cell migration, angiogenesis, and tumor metastasis
87. Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated Kinase 1/2 activation in postcapillary endothelium
88. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR
89. Effect of indomethacin on capillary growth and microvasculature in chronically stimulated rat skeletal muscles
90. i
91. PTK787/ZK222584, an inhibitor of vascular endothelial growth factor receptors, attenuates VEGF-induced increases in hydraulic conductivity (Lp) in frog mesenteric microvessels in vivo
92. In vivo Mechanisms of Vascular Endothelial Growth Factor Mediated Increased Hydraulic Conductivity of Rana Capillaries
93. i) in frog mesenteric microvessels in vivo
94. VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix
95. Covalent dimerization of vascular permeability factor/vascular endothelial growth factor is essential for its biological activity. Evidence from Cys to Ser mutations
96. Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor
97. Induction of VEGF and VEGF receptor gene expression by hypoxia: Divergent regulation in vivo and in vitro
98. Studies on inflammation. III. Growing capillaries: Their structure and permeability
99. A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF
100. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
101. A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines
102. Purification and NH2-terminal amino acid sequence of guinea pig tumor-secreted vascular permeability factor
103. The distensibility of single capillaries and venules in the cat mesentery
104. Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain
105. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
106. Formation and regression of capillary sprouts in corpora lutea of immature superstimulated golden hamsters
107. Exchange of macromolecules across the microcirculation
108. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
109. The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
110. VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain
111. Expression of vascular permeability factor in glioblastoma specimens: Correlation with tumor vascular endothelial surface and peritumoral edema
112. A three-dimensional junction-pore-matrix model for capillary permeability
113. Hypoxia-inducible factor-1alpha is regulated at the post-mRNA level
114. Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase
115. Heterogeneous vascular endothelial growth factor (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant
116. ZM323881, an inhibitor of vascular endothelial growth factor receptors, attenuates VEGF-induced increases in hydraulic conductivity (Lp) in frog mesenteric microvessels in vivo
117. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
118. VEGF induces NO-dependent hyperpermeability in coronary venules
119. Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation
120. Role of phospholipase C, protein kinase C, and calcium in VEGF-induced venular hyperpermeability
121. Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth
122. Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases
123. Control of hair growth and follicle size by VEGF-mediated angiogenesis
124. Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation
125. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family