Esterolytic antibodies as mechanistic and structural models of hydrolases - A quantitative analysis

Journal of Molecular Biology

Volumn 320, Issue 3, 2002, Pages 559-572

  Lindner, Ariel B ^a   Kim, Se Ho ^a   Schindler, Dan G ^a   Eshhar, Zelig ^a   Tawfik, Dan S ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Catalytic antibodies; Chemical rescue; Conformational changes; Oxyanion hole; nucleophile

Indexed keywords

ANTIBODY; CARBOXYLESTERASE; HYDROLASE; HYDROXIDE; PEROXIDE; SERINE PROTEINASE; TYROSINE;

ARTICLE; CATALYSIS; CATALYST; CONFORMATIONAL TRANSITION; HYDROGEN BOND; HYDROLYSIS; KINETICS; MUTAGENESIS; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

EID: 0036314854     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00418-7     Document Type: Article

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